Harada Takeshi 原田武志

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HARADA Takeshi 原田武志

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Researcher Number	10618359
Other IDs
Affiliation (Current)	2025: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授
Affiliation (based on the past Project Information) *help	2021 – 2024: 徳島大学, 大学院医歯薬学研究部(医学域), 准教授 2020: 徳島大学, 大学院医歯薬学研究部(医学域), 助教 2018 – 2019: 徳島大学, 病院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 54010:Hematology and medical oncology-related Except Principal Investigator Basic Section 57060:Surgical dentistry-related / Basic Section 57020:Oral pathobiological science-related / Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related / Basic Section 90140:Medical technology assessment-related / Basic Section 90130:Medical systems-related / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 血液腫瘍学 / 二本鎖RNA / ADAR / HDAC1 / ADAR1 / 多発性骨髄腫 / TAK1 / HTLV-1 / PIM1 / NF-kB … More / 成人T細胞白血病リンパ腫 / Cancer metabolism / HDAC / 腫瘍メタボリズム … More Except Principal Investigator 骨髄腫 / 骨芽細胞 / 多発性骨髄腫 / 骨細胞 / 骨転移 / PP2A / 骨髄間質細胞 / 破骨細胞 / 脱リン酸化 / CIP2A / 画像情報 / 遺伝情報 / 肺がんCT検診 / 細胞外基質小胞 / PIM2 / 骨代謝 / 貧血 / TAK1 / バイオマーカー Less

骨形成環境による腫瘍排他的ニッチの分子機序の解明：新たながん治療戦略の可能性
- Principal Investigator
  
  寺町順平
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  Okayama University
肺がんCT検診の性能向上のための遺伝情報と画像情報の融合研究
- Principal Investigator
  
  河田佳樹
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 90130:Medical systems-related
  Basic Section 90140:Medical technology assessment-related
  Sections That Are Subject to Joint Review: Basic Section90130:Medical systems-related , Basic Section90140:Medical technology assessment-related
- Research Institution
  The University of Tokushima
骨細胞保護によるがんの骨転移新規治療戦略の開発
- Principal Investigator
  
  日浅雅博
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57060:Surgical dentistry-related
- Research Institution
  The University of Tokushima
分泌蛋白の網羅解析による骨髄腫の未知の病態形成/予後因子の探索と新規治療の開発
- Principal Investigator
  
  安倍正博
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  The University of Tokushima
RNA編集酵素ADARが司る骨髄腫の進展様式と免疫逃避機構の解明Principal Investigator
- Principal Investigator
  
  原田武志
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  The University of Tokushima
骨破壊腫瘍進展と骨病変形成における細胞内情報伝達系の恒常的活性化機構の解明と制御
- Principal Investigator
  
  寺町順平
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 57020:Oral pathobiological science-related
- Research Institution
  Okayama University
Development of a novel treatment toward prevention of HTLV-1 transmission and ATL disease onsetPrincipal Investigator
- Principal Investigator
  
  HARADA Takeshi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  The University of Tokushima
Roles of HDAC1/3 effecting on metabolic shift in myeloma cells; Development of a novel treatment strategy targeting metabolic shiftPrincipal Investigator
- Principal Investigator
  
  HARADA Takeshi
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation Book

[Book] 骨髄腫細胞におけるエピゲノム異常多発性骨髄腫 update -診断・治療の最新動向-2023
- Author(s)
  原田武志
- Total Pages
  6
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08455
[Book] くすぶり型多発性骨髄腫　別冊日本臨牀領域別症候群シリーズ No.30 血液症候群（第3版）Ｖ　－その他の血液疾患を含めて－2023
- Author(s)
  原田武志, 安倍正博
- Total Pages
  5
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08455
[Book] I章近年承認された抗がん薬-13．ダラツムマブ・ボルヒアルロニダーゼアルファ配合（ダラキューロ）. 最新のがん薬物療法 2023-20242023
- Author(s)
  原田武志, 安倍正博
- Total Pages
  3
- Publisher
  南江堂
- Data Source
  KAKENHI-PROJECT-22K08455
[Book] 骨粗鬆症の類縁疾患の診断と治療. 多発性骨髄腫. 最新の骨粗鬆症学 (第2版) -骨粗鬆症の最新知見-2023
- Author(s)
  原田武志, 安倍正博
- Total Pages
  7
- Publisher
  日本臨牀
- Data Source
  KAKENHI-PROJECT-22K08455
[Journal Article] Acute suppression of translation by hyperthermia enhances anti-myeloma activity of carfilzomib2024
- Author(s)
  Maruhashi Tomoko、Miki Hirokazu、Sogabe Kimiko、Oda Asuka、Sumitani Ryohei、Oura Masahiro、Takahashi Mamiko、Harada Takeshi、Fujii Shiro、Nakamura Shingen、Kurahashi Kiyoe、Endo Itsuro、Abe Masahiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 3 Pages: 291-302
- DOI
  10.1007/s12185-023-03706-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08455
[Journal Article] Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid2024
- Author(s)
  Inoue Yusuke、Oda Asuka、Maeda Yusaku、Sumitani Ryohei、Oura Masahiro、Sogabe Kimiko、Maruhashi Tomoko、Takahashi Mamiko、Fujii Shiro、Nakamura Shingen、Miki Hirokazu、Hiasa Masahiro、Teramachi Jumpei、Harada Takeshi、Abe Masahiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 6 Pages: 626-630
- DOI
  10.1007/s12185-024-03763-7
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K08455
[Journal Article] Acute accumulation of PIM2 and NRF2 and recovery of β5 subunit activity mitigate multiple myeloma cell susceptibility to proteasome inhibitors2024
- Author(s)
  Sogabe K、Nakamura S、Higa Y、Miki H、Oda A、Maruhashi T、Sumitani R、Oura M、Takahashi M、Nakamura M、Maeda Y、Hara T、Yamagami H、Fujii S、Kagawa K、Ozaki S、Kurahashi K、Endo I、Aihara K、Nakaue E、Hiasa M、Teramachi J、Harada T、Abe M
- Journal Title
  
  International Journal of Hematology
  
  Volume: 119 Issue: 3 Pages: 303-315
- DOI
  10.1007/s12185-023-03705-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-22K08455, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K27791
[Journal Article] Mechanisms of preferential bone formation in myeloma bone lesions by proteasome inhibitors2023
- Author(s)
  Nakaue Emiko、Teramachi Jumpei、Tenshin Hirofumi、Hiasa Masahiro、Harada Takeshi、Oda Asuka、Inoue Yusuke、Shimizu So、Higa Yoshiki、Sogabe Kimiko、Oura Masahiro、Hara Tomoyo、Sumitani Ryohei、Maruhashi Tomoko、Yamagami Hiroki、Endo Itsuro、Tanaka Eiji、Abe Masahiro
- Journal Title
  
  International Journal of Hematology
  
  Volume: - Issue: 1 Pages: 88-98
- DOI
  10.1007/s12185-023-03601-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08455, KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-23K15975, KAKENHI-PROJECT-23K19694, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K27791
[Journal Article] Therapeutic efficacy of the resorcylic acid lactone LL‐Z1640‐2 for adult T‐cell leukaemia/lymphoma2023
- Author(s)
  Oura M、Harada T、Oda A、Teramachi J、Nakayama A、Sumitani R、Inoue Y、Maeda Y、Sogabe K、Maruhashi T、Takahashi M、Fujii S、Nakamura S、Miki H、Nakamura M、Hara T、Yamagami H、Kurahashi K、Endo I、Hasegawa H、Fujiwara H、Abe M
- Journal Title
  
  eJHaem
  
  Volume: 4 Issue: 3 Pages: 667-678
- DOI
  10.1002/jha2.758
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K24233, KAKENHI-PROJECT-23K27455
[Journal Article] Myeloma bone disease: pathogenesis and management in the era of new anti-myeloma agents2023
- Author(s)
  Teramachi Jumpei、Miki Hirokazu、Nakamura Shingen、Hiasa Masahiro、Harada Takeshi、Abe Masahiro
- Journal Title
  
  Journal of Bone and Mineral Metabolism
  
  Volume: - Issue: 3 Pages: 388-403
- DOI
  10.1007/s00774-023-01403-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08455, KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-23K21485
[Journal Article] Novel antimyeloma therapeutic option with inhibition of the HDAC1-IRF4 axis and PIM kinase2023
- Author(s)
  Harada Takeshi、Ohguchi Hiroto、Oda Asuka、Nakao Michiyasu、Teramachi Jumpei、Hiasa Masahiro、Sumitani Ryohei、Oura Masahiro、Sogabe Kimiko、Maruhashi Tomoko、Takahashi Mamiko、Fujii Shiro、Nakamura Shingen、Miki Hirokazu、Kagawa Kumiko、Ozaki Shuji、Sano Shigeki、Hideshima Teru、Abe Masahiro
- Journal Title
  
  Blood Advances
  
  Volume: 7 Issue: 6 Pages: 1019-1032
- DOI
  10.1182/bloodadvances.2022007155
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-20K08734, KAKENHI-PROJECT-23K21485
[Journal Article] The Xanthine Oxidase Inhibitor Febuxostat Suppresses Adipogenesis and Activates Nrf22023
- Author(s)
  Higa Y, Hiasa M, Tenshin H, Nakaue E, Tanaka M, Kim S, Nakagawa M, Shimizu S, Tanimoto K, Teramachi J, Harada T, Oda A, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Yamagami H, Endo I, Matsumoto T, Tanaka E, Abe M
- Journal Title
  
  Antioxidants
  
  Volume: 12 Issue: 1 Pages: 133-133
- DOI
  10.3390/antiox12010133
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K08455, KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-22H03104, KAKENHI-PROJECT-21K21016, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K15975, KAKENHI-PROJECT-23K16151, KAKENHI-PROJECT-23K19694
[Journal Article] The importance of retaining physical functions to prevent skeletal-related events in multiple myeloma patients with bone disease2022
- Author(s)
  Hirokazu Miki,Shingen Nakamura,Masahiro Oura,Masafumi Nakamura,Ryohei Sumitani,Kimiko Sogabe,Mamiko Takahashi,Tomoko Maruhashi,Takeshi Harada,Shiro Fujii,Hirofumi Hamano,Masateru Kondo,Naoto Okada,Itsuro Endo,Masahiro Abe
- Journal Title
  
  eJHaem
  
  Volume: － Issue: 2 Pages: 480-483
- DOI
  10.1002/jha2.402
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08712, KAKENHI-PROJECT-21K16244, KAKENHI-PROJECT-22H03104
[Journal Article] TGF‐β‐activated kinase‐1 inhibitor LL‐Z1640‐2 reduces joint inflammation and bone destruction in mouse models of rheumatoid arthritis by inhibiting NLRP3 inflammasome, TACE, TNF‐α and RANKL expression2022
- Author(s)
  Tenshin H, Teramachi J, Ashtar M, Hiasa M, Inoue Y, Oda A, Tanimoto K, Shimizu S, Higa Yi, Harada T, Oura M, Sogabe K, Hara T, Sumitani R, Maruhashi T, Sebe M, Tsutsumi R, Sakaue H, Endo I, Matsumoto T, Tanaka E, Abe M
- Journal Title
  
  Clinical & Translational Immunology
  
  Volume: 11 Issue: 1
- DOI
  10.1002/cti2.1371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22719, KAKENHI-PROJECT-20K18784, KAKENHI-PROJECT-17KK0169, KAKENHI-PROJECT-19H04055, KAKENHI-PROJECT-22K19626, KAKENHI-PROJECT-23K21485, KAKENHI-PROJECT-23K24792
[Journal Article] Myeloma-Bone Interaction: A Vicious Cycle via TAK1-PIM2 Signaling2021
- Author(s)
  1. Harada T, Hiasa M, Teramachi J, Abe M
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 17 Pages: 4441-4441
- DOI
  10.3390/cancers13174441
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K08329, KAKENHI-PROJECT-19K22719, KAKENHI-PROJECT-20K17402, KAKENHI-PROJECT-17KK0169
[Journal Article] Targeting histone deacetylase 3 (HDAC3) in the bone marrow microenvironment inhibits multiple myeloma proliferation by modulating exosomes and IL-6 trans-signaling2019
- Author(s)
  Ho Matthew、Chen Tianzeng、Liu Jiye、Dowling Paul、Hideshima Teru、Zhang Li、Morelli Eugenio、Camci-Unal Gulden、Wu Xinchen、Tai Yu-Tzu、Wen Kenneth、Samur Mehmet、Schlossman Robert L.、Mazitschek Ralph、Kavanagh Emma L.、Lindsay Sinead、Harada Takeshi、McCann Amanda、Anderson Kenneth C.、O’Gorman Peter、Bianchi Giada
- Journal Title
  
  Leukemia
  
  Volume: 34 Issue: 1 Pages: 196-209
- DOI
  10.1038/s41375-019-0493-x
- NAID
  120006999404
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K16118
[Journal Article] PD-L1 upregulation in myeloma cells by panobinostat in combination with interferon-γ.2019
- Author(s)
  Iwasa Masami、Harada Takeshi、Oda Asuka、Bat-Erdene Ariunzaya、Teramachi Jumpei、Tenshin Hirofumi、Ashtar Mohannad、Oura Masahiro、Sogabe Kimiko、Udaka Kengo、Fujii Shiro、Nakamura Shingen、Miki Hirokazu、Kagawa Kumiko、Ozaki Shuji、Abe Masahiro
- Journal Title
  
  Oncotarget
  
  Volume: 10 Issue: 20 Pages: 1903-1917
- DOI
  10.18632/oncotarget.26726
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17KK0169, KAKENHI-PROJECT-16K11504, KAKENHI-PROJECT-17K09956, KAKENHI-PROJECT-18K16118, KAKENHI-PROJECT-19K21382
[Journal Article] Class 1 HDAC and HDAC6 inhibition inversely regulates CD38 induction in myeloma cells via interferon-α and ATRA2018
- Author(s)
  Bat-Erdene Ariunzaya、Nakamura Shingen、Oda Asuka、Iwasa Masami、Teramachi Jumpei、Ashtar Mohannad、Harada Takeshi、Miki Hirokazu、Tenshin Hirofumi、Hiasa Masahiro、Fujii Shiro、Sogabe Kimiko、Oura Masahiro、Udaka Kengo、Kagawa Kumiko、Yoshida Sumiko、Aihara Ken-ichi、Kurahashi Kiyoe、Endo Itsuro、Abe Masahiro
- Journal Title
  
  British Journal of Haematology
  
  Volume: 印刷中 Issue: 5 Pages: 969-974
- DOI
  10.1111/bjh.15673
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K11504, KAKENHI-PROJECT-18K08329, KAKENHI-PROJECT-17KK0169, KAKENHI-PROJECT-17H05104, KAKENHI-PROJECT-19K17858, KAKENHI-PROJECT-18K16118
[Presentation] 1q増幅骨髄腫微小環境でのSLAMF7が介在する炎症ネットワーク2023
- Author(s)
  原田武志、小田明日香、住谷龍平、井上雄介、原倫世、大浦雅博、曽我部公子、丸橋朋子、高橋真美子、藤井志朗、中村信元、三木浩和、日浅雅博、寺町順平、安倍正博
- Organizer
  第85回日本血液学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 骨髄腫の進展における可溶性SLAMF7による炎症惹起の役割2023
- Author(s)
  原田武志、住谷龍平、原倫世、井上雄介、中上絵美子、天眞寛文、小田明日香、大浦雅博、曽我部公子、丸橋朋子、高橋真美子、藤井志朗、中村信元、三木浩和、日浅雅博、寺町順平、菊池次郎、古川雄祐、安倍正博
- Organizer
  第49回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 骨髄腫骨病変由来可溶型 SLAMF7 の骨病変微小環境に及ぼす影響の解明2023
- Author(s)
  原田武志，住谷龍平，原倫世，天眞寛文，中上絵美子，井上雄介，日浅雅博，寺町順平，田中栄二，遠藤逸朗，安倍正博
- Organizer
  第41回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 骨形成誘導による骨髄腫排他的ニッチ形成の分子機序の探索2023
- Author(s)
  金秀河，寺町順平，日浅雅博，天真寛文，中上絵美子，田中茉里子，中川宗純，遠藤逸朗，原田武志，田中栄二，安倍正博
- Organizer
  第41回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 不動は骨髄腫骨病変部 DPP-4 発現増加と骨髄腫の腫瘍進展・髄外播種を加速させる2022
- Author(s)
  田中茉里子，日浅雅博，谷本幸多朗，天真寛文，清水宗，比嘉佳基，中上絵美子，金秀河，寺町順平，原田武志，中村信元，遠藤逸朗，田中栄二，松本俊夫，安倍正博
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 破骨細胞は SLAMF7 を強発現し可溶性 SLAMF7 を産生する2022
- Author(s)
  天真寛文、原田武志、井上雄介、菊池次郎、小田明日香、住谷龍平、大浦雅博、曽我部公子、丸橋朋子、高橋真美子、藤井志朗、中村信元、三木浩和、日浅雅博、寺町順平、鈴木敦、角川学士、峯畑健一、古川雄祐、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] TAK1 阻害は骨髄腫の細胞間相互作用による骨破壊と薬剤耐性を改善する2022
- Author(s)
  寺町順平、天真寛文、原田武志、日浅雅博、小田明日香、清水宗、住谷龍平、大浦雅博、曽我部公子、丸橋朋子、藤井志朗、中村信元、三木浩和、遠藤逸朗、原田武志、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] RNA 編集酵素 ADAR1 を標的にする 1q 増幅骨髄腫細胞に対する治療法の開発2022
- Author(s)
  原田武志、住谷龍平、小田明日香、井上雄介、大浦雅博、曽我部公子、丸橋朋子、高橋真美子、藤井志朗、中村信元、三木浩和、天眞寛文、日浅雅博、寺町順平、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] プロテアソーム阻害薬による骨髄腫骨病変部選択的骨形成誘導活性の検討2022
- Author(s)
  中上絵美子、天真寛文、日浅雅博、寺町順平、原田武志、井上雄介、谷本幸多郎、清水宗、比嘉佳基、遠藤逸郎、田中栄二、松本俊夫、安倍正博
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 破骨細胞による SLAMF7 の産生と骨髄腫関連骨病変に対する SLAMF7 標的療法の開発2022
- Author(s)
  原田武志，天眞寛文，井上雄介，住谷龍平，中上絵美子，寺町順平，日浅雅博，田中栄二，松本俊夫，安倍正博
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 骨髄腫骨髄微小環境の変容におけるキサンチンオキシダーゼ -ROS 経路の重要な役割2022
- Author(s)
  比嘉佳基、日浅雅博、天真寛文、谷本幸多郎、清水宗、寺町順平、原田武志、小田明日香、遠藤逸郎、松本俊夫、田中栄二、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] 骨髄腫に対する抗体免疫療法への Th1 様γδ T 細胞の応用2022
- Author(s)
  井上雄介、原田武志、天眞寛文、小田明日香、住谷龍平、大浦雅博、曽我部公子、丸橋朋子、高橋真美子、藤井志朗、中村信元、三木浩和、日浅雅博、寺町順平、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] キサンチンオキシダーゼ (XO) 阻害薬 febuxostat による脂肪細胞分化と骨芽細胞分化の制御機構2022
- Author(s)
  比嘉佳基、日浅雅博、天真寛文、寺町順平、原田武志、小田明日香、遠藤逸郎、松本俊夫、田中栄二、安倍正博
- Organizer
  第40回日本骨代謝学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] ADAR1-dsRNA metabolism in myeloma cells with 1q amplification: a novel therapeutic target2022
- Author(s)
  Harada T, Oda A, Matsushita Y, Sumitani R, Inoue Y, Hara T, Oura M, Sogabe K, Maruhashi T, Takahashi M, Kurahashi K, Fujii S, Nakamura S, Miki H, Hiasa M, Teramachi J, Katagiri T, Abe M.
- Organizer
  19th International Myeloma Society Annual Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K08455
[Presentation] プロテアソーム阻害薬のパルス投与の骨代謝への影響2022
- Author(s)
  中上絵美子、天真寛文、寺町順平、日浅雅博、原田武志、谷本幸多郎、清水宗、比嘉佳基、住谷龍平、丸橋朋子、大浦雅博、曽我部公子、中村信元、三木浩和、遠藤逸郎、田中栄二、安倍正博
- Organizer
  第47回日本骨髄腫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K21485
[Presentation] The therapeutic potential targeting ADAR1-dsRNA metabolism in myeloma cells with 1q amplification2022
- Author(s)
  Harada T, Sumitani R, Oda A, Inoue Y, Oura M, Sogabe K, Maruhashi T, Takahashi M, Fujii S, Nakamura S, Miki H, Kagawa K, Ozaki S, Tenshin H, Hiasa M, Teramachi J, Abe M.
- Organizer
  The 84th Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-22K08455
[Presentation] Therapeutic impact of targeting RNA editing enzyme ADAR1 on myeloma cells with 1q amplification2022
- Author(s)
  Harada T, Sumitani R, Oda A, Inoue Y, Oura M, Sogabe K, Maruhashi T, Takahashi M, Fujii S, Nakamura S, Miki H, Tenshin H, Hiasa M, Teramachi J, Abe M.
- Organizer
  The 47th Annual Meeting of the Japanese Society of Myeloma
- Data Source
  KAKENHI-PROJECT-22K08455
[Presentation] Efficacious therapeutic potential of targeting PIM kinases in ATL2021
- Author(s)
  Oura M, Harada T, Teramachi J, Nakayama A, Oda A, Inoue Y, Sogabe K, Sumitani R, Fujii S, Nakamura S, Miki H, Kagawa K, Hasegawa H, Fujiwara H, Abe M
- Organizer
  The 83rd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-20K17402
[Presentation] Critical roles of the TAK1-c-Myc loop as a novel therapeutic target for ATL2020
- Author(s)
  Oura M, Harada T, Teramachi J, Oda A, Inoue Y, Sogabe K, Sumitani R, Fujii S, Nakamura S, Miki H, Kagawa K, Hasegawa H, Fujiwara H, Abe M
- Organizer
  The 82nd Annual Meeting of the Japanese Society of Hematology
- Data Source
  KAKENHI-PROJECT-20K17402
[Presentation] Novel therapeutic rationale for targeting HDAC1 and PIM2 in multiple myeloma.2019
- Author(s)
  Harada T, Oda A, Ohguchi H, Grondin Y, Tenshin H, Hiasa M, Teramachi J, Oura M, Sogabe K, Fujii S, Nakamura S, Miki H, Kagawa K, Ozaki S, Hideshima T, Anderson KC, Abe M.
- Organizer
  The 61th Annual Meeting of the American Society of Hematology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] 多発性骨髄腫におけるHDACアイソフォームの役割とその選択的阻害による治療法の開発2019
- Author(s)
  原田武志
- Organizer
  第81回日本血液学会学術集会
- Invited
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] Targeting myeloma metabolisoms regulated by HDAC1-IRF4 axis can be a novel therapeutic strategy.2019
- Author(s)
  Harada T, Oda A, Tenshin H, Teramachi J, Oura M, Sogabe K, Fujii S, Nakamura S, Miki H, Kagawa K, Ozaki S, Hideshima T, Anderson KC, Abe M.
- Organizer
  The 17th International Myeloma Workshop
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] The novel therapeutic strategy targeting the HDAC1-IRF4-PIM2 pathway in myeloma cells.2019
- Author(s)
  Harada T, Oda A, Tenshin H, Teramachi J, Oura M, Sogabe K, Iwasa M, Fujii S, Nakamura S, Miki H, Kagawa K, Hideshima T, Anderson KC, Abe M.
- Organizer
  The 44rd Annual Meeting of the Japanese Society of Myeloma
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] The critical role of the HDAC1-IRF4-Pim-2 axis in myeloma cell growth and survival: therapeutic impacts of targeting the HDAC1-IRF4-Pim-2 axis2018
- Author(s)
  Harada T, Oda A, Grondin Y, Teramachi J, Bat-Erdene A, Iwasa M, Oura M, Nakamura S, Kagawa K, Okamoto Y, Sogabe K, Fujii S, Miki H, Ozaki S, Hideshima T, Anderson KC, Abe M
- Organizer
  The 60th ASH Annual Meeting & Exposition
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] Roles of HDAC1 and HDAC3 as therapeutic targets against myeloma cells2018
- Author(s)
  Harada T
- Organizer
  The 80th Annual Meeting of the Japanese Society of Hematology
- Invited
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] Selective inhibition of class-I HDAC induces myeloma cell death through targeting IRF4-Pim-2 axis2018
- Author(s)
  Harada T, Oda A, Teramachi J, Bat-Erdene A, Iwasa M, Oura M, Nakamura S, Kagawa K, Okamoto Y, Sogabe K, Fujii S, Miki H, Ozaki S, Hideshima T, Anderson KC, Abe M
- Organizer
  The 9th JSH International Symposium 2018 in Kyoto
- Data Source
  KAKENHI-PROJECT-18K16118
[Presentation] HDAC1/3 inhibition disrupts the IRF4-Pim-2 pathway to induce effective myeloma cell death2018
- Author(s)
  Harada T, Oda A, Teramachi J, Bat-Erdene A, Iwasa M, Maeda Y, Nakamura S, Oura M, Fujii S, Miki H, Kagawa K, Hideshima T, Anderson KC, Abe M
- Organizer
  The 43rd Annual Meeting of the Japanese Society of Myeloma
- Data Source
  KAKENHI-PROJECT-18K16118

1. 寺町順平 (20515986)

# of Collaborated Projects: 3 results

# of Collaborated Products: 19 results
2. 日浅雅博 (90511337)

# of Collaborated Projects: 3 results

# of Collaborated Products: 15 results
3. 安倍正博 (80263812)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 沢禎彦 (70271666)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 冨永辰也 (80425446)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 河田佳樹 (70274264)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 仁木登 (80116847)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 楠本昌彦 (90252767)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 土田敬明 (80256239)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 松元祐司 (00600579)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 井本逸勢 (30258610)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 遠藤逸朗 (10432759)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 米田俊之 (80142313)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 安部正博

# of Collaborated Projects: 0 results

# of Collaborated Products: 15 results
15. 三木浩和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Harada Takeshi 原田 武志

HARADA Takeshi 原田 武志

Research Projects

Research Products

Co-Researchers

骨形成環境による腫瘍排他的ニッチの分子機序の解明：新たながん治療戦略の可能性

Principal Investigator

Project Period (FY)

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Research Institution

肺がんCT検診の性能向上のための遺伝情報と画像情報の融合研究

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

骨細胞保護によるがんの骨転移新規治療戦略の開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分泌蛋白の網羅解析による骨髄腫の未知の病態形成/予後因子の探索と新規治療の開発

Principal Investigator

Project Period (FY)

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RNA編集酵素ADARが司る骨髄腫の進展様式と免疫逃避機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

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骨破壊腫瘍進展と骨病変形成における細胞内情報伝達系の恒常的活性化機構の解明と制御

Principal Investigator

Project Period (FY)

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Research Institution

Development of a novel treatment toward prevention of HTLV-1 transmission and ATL disease onsetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Roles of HDAC1/3 effecting on metabolic shift in myeloma cells; Development of a novel treatment strategy targeting metabolic shiftPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Book] 骨髄腫細胞におけるエピゲノム異常 多発性骨髄腫 update -診断・治療の最新動向-2023

Author(s)

Total Pages

Publisher

Data Source

[Book] くすぶり型多発性骨髄腫 別冊 日本臨牀 領域別症候群シリーズ No.30 血液症候群（第3版）Ｖ －その他の血液疾患を含めて－2023

Author(s)

Total Pages

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Data Source

[Book] I章 近年承認された抗がん薬-13．ダラツムマブ・ボルヒアルロニダーゼ アルファ配合（ダラキューロ）. 最新のがん薬物療法 2023-20242023

Author(s)

Total Pages

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Data Source

[Book] 骨粗鬆症の類縁疾患の診断と治療. 多発性骨髄腫. 最新の骨粗鬆症学 (第2版) -骨粗鬆症の最新知見-2023

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Total Pages

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[Journal Article] Acute suppression of translation by hyperthermia enhances anti-myeloma activity of carfilzomib2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Ex vivo expansion and activation of Vγ9Vδ2 T cells by CELMoDs in combination with zoledronic acid2024

Author(s)

Harada Takeshi 原田武志

HARADA Takeshi 原田武志

[Book] 骨髄腫細胞におけるエピゲノム異常多発性骨髄腫 update -診断・治療の最新動向-2023

[Book] くすぶり型多発性骨髄腫　別冊日本臨牀領域別症候群シリーズ No.30 血液症候群（第3版）Ｖ　－その他の血液疾患を含めて－2023

[Book] I章近年承認された抗がん薬-13．ダラツムマブ・ボルヒアルロニダーゼアルファ配合（ダラキューロ）. 最新のがん薬物療法 2023-20242023