HIRASHIMA TSUYOSHI 平島剛志

Researcher Number	10620198
Other IDs	https://orcid.org/0000-0001-7323-9627
Affiliation *help	2017 – 2018 : 京都大学, 医学研究科, 講師 2017 : 京都大学, 医学(系)研究科(研究院), 講師 2016 : 京都大学, ウイルス・再生医科学研究所, 特定助教 2015 : 京都大学, 再生医科学研究所, 特定助教 2012 – 2013 : 京都大学, ウイルス研究所, 特別研究員(PD) 2010 : 九州大学, 大学院・理学研究院, 特別研究員(DC2) 2009 : Kyushu University, 理学研究院, 特別研究員(DC2)
Review Section/Research Field	Principal Investigator Constructive Systems Biology / Developmental biology Except Principal Investigator Biophysics / Developmental biology / Biological Sciences
Keywords	Principal Investigator 数理モデル / メカノバイオロジー / ライブイメージング / 形態形成 / サイズ維持 / 肺上皮 / バーテクスモデル / 多細胞力学応答 / 多細胞動態の数理モデル / 多細胞ライブイメージング … More Except Principal Investigator イメージング / 精巣上体細管の発生 / 細胞生物学 / 腎管芽発生 / 器官形成 / 分岐形態形成 / Cellular Potts Model / シグナル制御 / 数理モデル / 蛍光タンパク質 / 分子プローブ / 多細胞動態 / 尿管芽 / タンパク質リン酸化酵素 / 蛍光バイオセンサー / ライブイメージング / FRETバイオセンサー / レトロアクティビティ / 内臓の形態形成 / FRET / 肺発生 / 遺伝子制御ネットワーク / MAPK / 再生 / 数理モデリング / 蛍光共鳴エネルギー移動 Less

管径の恒常性維持に働く細胞力覚システムの応答特性の解明Principal InvestigatorOngoing
- Principal Investigator
  
  平島剛志
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Constructive Systems Biology
- Research Institution
  Kyoto University
Elucidation of a force-dependent mechanism for maintaining radial size of epithelial tubesPrincipal Investigator
- Principal Investigator
  
  平島剛志
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Developmental biology
- Research Institution
  Kyoto University
Live imaging of cell-to-cell communicationOngoing
- Principal Investigator
  
  松田道行
- Project Period (FY)
  2015 – 2019
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Kyoto University
分岐器官の形態形成過程における細胞運動の測定と数理モデリングResearch Fellow
- Research Fellow
  
  平島剛志
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Biophysics
- Research Institution
  Kyoto University
分岐形態形成のダイナミックモデリングResearch Fellow
- Research Fellow
  
  平島剛志
- Project Period (FY)
  2009 – 2010
- Research Category
  
  Grant-in-Aid for JSPS Fellows
- Research Field
  
  Developmental biology
- Research Institution
  Kyushu University

All 2017 2016 2015 2014 2013 2012 2010 2009

All Journal Article Presentation

[Journal Article] Cellular Potts Modeling of Complex Multicellular Behaviors in Tissue Morphogenesis2017
- Author(s)
  Tsuyoshi Hirashima, Elisabeth G. Rens, and Roeland M.H. Merks
- Journal Title
  
  Development, Growth & Differentiation
  
  Volume : 59 Pages : 329-339
- DOI
  10.1111/dgd.12358
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Journal Article] In vitro tubulogenesis of Madin-Darby canine kidney (MDCK) spheroids occurs depending on constituent cell number and scaffold gel concentration2017
- Author(s)
  Tsuyoshi Hirashima, Miho Hoshuyama, and Taiji Adachi
- Journal Title
  
  Journal of Theoretical Biology
  
  Volume : 435 Pages : 110-115
- DOI
  10.1016/j.jtbi.2017.09.009
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18541
[Journal Article] 上皮管組織の異方的な成長を支える協調的な多細胞動態と力学2016
- Author(s)
  平島剛志
- Journal Title
  
  生体の科学
  
  Volume : 67
- Data Source
  KAKENHI-PROJECT-15K18541
[Journal Article] Mathematical Study on Robust Tissue Pattern Formation in Growing Epididymal Tubule2016
- Author(s)
  Hirashima Tsuyoshi
- Journal Title
  
  Journal of Theoretical Biology
  
  Volume : 407 Pages : 71-80
- DOI
  10.1016/j.jtbi.2016.07.005
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K18541
[Journal Article] Procedures for the Quantification of Whole-Tissue Immunofluorescence Images Obtained at Single-Cell Resolution during Murine Tubular Organ Development2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Journal Title
  
  PLOS ONE
  
  Volume : 10 Issue : 8
- Publisher
  Public Library of Science
- DOI
  10.1371/journal.pone.0135343
- PMID
  26258587
- Year and Date
  2015-08-10
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K18541
[Journal Article] On Fundamental Cellular Processes for Emergence of Collective Epithelial Movement.2013
- Author(s)
  Isuyoshi Hirashima, Yoichiroh Hosokawa, Takanori Iino, Masaharu Nagavama
- Journal Title
  
  Biology Open
  
  Volume : (印刷中)
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03338
[Journal Article] Cellular Potts Model on Collective Cell Movement.2013
- Author(s)
  Tsuyoshi Hirashima
- Journal Title
  
  RIMS KokyQroku
  
  Volume : (印刷中)
- Data Source
  KAKENHI-PROJECT-12J03338
[Journal Article] Cellular Potts Model on Collective Cell Movement2013
- Author(s)
  T. Hirashima
- Journal Title
  
  RIMS Kôkyûroku
  
  Volume : 1853 Pages : 49-55
- Data Source
  KAKENHI-PROJECT-12J03338
[Journal Article] On fundamental cellular processes for emergence of collective epithelial movement2013
- Author(s)
  T. Hirashima, Y. Hosokawa, T. Iino, M. Nagayama
- Journal Title
  
  Biology Open
  
  Volume : 0 Pages : 1-7
- DOI
  10.1242/bio.20134523
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03338, KAKENHI-PROJECT-24360027
[Journal Article] A Kinetic Model of ERK Cyclic Pathway on Substrate Control.2012
- Author(s)
  Tsuyoshi Hirashima
- Journal Title
  
  Mathematical Biosciences
  
  Volume : 239 Pages : 207-212
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03338
[Journal Article] Mathematical Study of the Role of Delta/Notch Lateral Inhibition during Primary Branching of Drosophila Trachea Development.2012
- Author(s)
  Yoshiki Koizumi, Yoh Iwasa, Tsuyoshi Hirashima
- Journal Title
  
  Biophysical Journal
  
  Volume : 103 Pages : 2549-2559
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-12J03338
[Journal Article] Mechanisms for Split Localization of Fgf10 Expression in Early Lung Development2009
- Author(s)
  Hirashima T., et al.
- Journal Title
  
  Developmental Dynamics 238
  
  Pages : 2813-2822
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-09J03815
[Presentation] 多細胞動態・形態の定量による恒常的な管径維持システムの解明2017
- Author(s)
  平島剛志
- Organizer
  定量生物の会第８回年会
- Place of Presentation
  岡崎コンファレンスセンター
- Year and Date
  2017-01-08
- Invited
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] How to encounter endothelial cells in deep tissues - mechanical interaction between endothelial cells and epithelial tube.2017
- Author(s)
  Tsuyoshi Hirashima amd Taiji Adachi
- Organizer
  第50回日本発生生物学会年
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 上皮管の形態形成に働く細胞の力学応答システム2017
- Author(s)
  平島剛志、安達泰治
- Organizer
  第69回日本細胞生物学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Anisotropic Cellular Mechanoresponse Maintains the Radial Size of Developing Epididymal Tubules2017
- Author(s)
  平島剛志、安達泰治
- Organizer
  第55回日本生物物理学会
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Adaptive Multicellular Behaviors as Mechanoresponse for Radial Size Maintenance of Epithelial Tube2017
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  18th International Congress of Developmental Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 生体外培養下における管形成の誘導について2017
- Author(s)
  平島剛志、寳珠山美歩、安達泰治
- Organizer
  日本メカノバイオロジー学会第２回
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 増殖する上皮管の径サイズ恒常維持に働く適応的な多細胞動態システム2016
- Author(s)
  平島剛志、安達泰治
- Organizer
  日本発生生物学会秋季シンポジウム2016
- Place of Presentation
  三島市民文化会館
- Year and Date
  2016-10-19
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 増殖する上皮管の径サイズ恒常維持に働く適応的な多細胞動態システムについて2016
- Author(s)
  平島剛志、安達泰治
- Organizer
  第68回日本細胞生物学会・日本ケミカルバイオロジー学会第11回年回　合同大会
- Place of Presentation
  京都テルサ
- Year and Date
  2016-06-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 臓器の形態形成を支える細胞動態機構の解明に向けて2016
- Author(s)
  平島剛志、安達泰治
- Organizer
  生命動態システム科学四拠点・CREST・PREST合同シンポジウム
- Place of Presentation
  シャラトンホテル広島
- Year and Date
  2016-03-25
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Adaptive Cellular Behavior for Homeostatic Radial Size in Proliferating Tube2016
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  RIKEN CDB Symposium 2016- Size in Development
- Place of Presentation
  理研CDB、神戸
- Year and Date
  2016-03-28
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 組織の異方成長に関与する新たな細胞力覚システム2016
- Author(s)
  平島剛志、安達泰治
- Organizer
  第１回日本メカノバイオロジー学会学術大会
- Place of Presentation
  北海道大学
- Year and Date
  2016-03-01
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Adaptive Multicellular Dynamics via Directional Mechanosensing for Homeostatic Radial Size of Proliferating Tube2016
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  Mechanobiology from molecules to tissues, theory and applications
- Place of Presentation
  Quy Nhon, Vietnam
- Year and Date
  2016-06-26
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] On a Mechanism of Adaptive Cellular Behavior Achieving Stable Radial Size of a Developing Epithelial Tubule2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  第48回日本発生生物学会年会
- Place of Presentation
  つくば国際会議場
- Year and Date
  2015-06-03
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] 伸びてねじれる精巣上体細管のかたち作り2015
- Author(s)
  平島剛志
- Organizer
  第79回形の科学会シンポジウム「生物にみられるねじれ構造」
- Place of Presentation
  千葉工業大学
- Year and Date
  2015-06-13
- Invited
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] On Dynamic Cellular Behaviors Realizing Stable Radial Size in Developing Epithelial Tubule2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  第53回日本生物物理学会
- Place of Presentation
  金沢大学
- Year and Date
  2015-09-14
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Adaptive Cellular Behaviors Realizing Homeostatic Radial Size in Developing Epithelial Tubule2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  Commemorative Symposium for the 31st International Prize for Biology
- Place of Presentation
  京都国際会議場
- Year and Date
  2015-12-05
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Modeling Apical Surface Dynamics in Elongating Tubule Morphogenesis2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  2015年日本数理生物学会/日中韓数理生物学コロキウム合同大会
- Place of Presentation
  同志社大学
- Year and Date
  2015-08-26
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] Cellular Surface Dynamics of Biological Tube for Homeostatic Radial Size2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  iCeMS International Symposium - Hierarchical Dynamics in Soft Materials and Biological Matter
- Place of Presentation
  京都大学
- Year and Date
  2015-09-24
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] On Dynamic Cellular Behaviors Realizing Homeostatic Radial Size in Developing Epithelial Tubule2015
- Author(s)
  Tsuyoshi Hirashima and Taiji Adachi
- Organizer
  EMBL symposium - Physics of Cells and Tissues
- Place of Presentation
  EMBL, Heidelberg
- Year and Date
  2015-09-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K18541
[Presentation] On the formation of localized folding of epithelial tube in epididymis development2014
- Author(s)
  T. Hirashima
- Organizer
  Workshop on Mechanics and Growth of Tissue from Development to Cancer
- Place of Presentation
  Paris, France
- Year and Date
  2014-01-14
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] Pattern formation of epithelial tube by mechanical instability in murine epi didymis development2014
- Author(s)
  T. Hirashima
- Organizer
  RIKEN CDB Symposium 2014
- Place of Presentation
  Kobe, Japan
- Year and Date
  2014-03-11
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] How To Achieve Sequential Local Folding of Epithelial Tube in Epididymis Development : Experimental and Mathematical Study2013
- Author(s)
  T. Hirashima and R. Kageyama
- Organizer
  日本生物物理学会第51回年会
- Place of Presentation
  国立京都国際会館
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] 実験と計算で探る細胞の自己組織化過程2013
- Author(s)
  平島剛志
- Organizer
  第4回グリーンフォトニクスセミナー
- Place of Presentation
  京都
- Year and Date
  2013-12-12
- Invited
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] マウスの精巣上体管の折れたたみ形態形成2013
- Author(s)
  平島剛志
- Organizer
  定量生物学の会第五回年会
- Place of Presentation
  大阪大学
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] 精巣上体発生過程における管の折れ畳み形成の数理モデル2013
- Author(s)
  平島剛志
- Organizer
  第23回日本数理生物学会大会
- Place of Presentation
  静岡大学
- Year and Date
  2013-09-11
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] 細胞集団の運動を扱うCellular Potts Model - 皮膚細胞を用いた実験観察とともに2012
- Author(s)
  平島剛志
- Organizer
  RIMS研究集会
- Place of Presentation
  京都大学
- Year and Date
  2012-11-14
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] Larger Intercellular Adhesion Strength Generates More Coherent and Directional Multicellular Movement2012
- Author(s)
  平島剛志
- Organizer
  第50回日本生物物理学会
- Place of Presentation
  名古屋大学
- Year and Date
  2012-09-22
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] Higher Ca2^+ Concentration Triggers More Coherent and Directional Movement of Collective Skin Cell2012
- Author(s)
  平島剛志
- Organizer
  Joint Meeting of The 45th Annual Meeting of the Japanese Society of Developmental Biologists & The 64th Annual Meet ing of the Japan Society for Cell Biology
- Place of Presentation
  Kobe International Conference Center
- Year and Date
  2012-05-29
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] Collective Cell Movement of Skin Cells -Measurements and Simulation2012
- Author(s)
  Tsuyoshi Hirashima
- Organizer
  2012 Asia Pacific Developmental Biology Confercnce
- Place of Presentation
  Taipei, Taiwan
- Year and Date
  2012-10-07
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] Strong Intercellular Adhesion Is Sufficient for Generating Coherent and Directional Movement of Skin Cells2012
- Author(s)
  Tsuyoshi Hirashima
- Organizer
  EMBO Conference Series- Morphogenesis and Dynamics of Multicellular Systems
- Place of Presentation
  Heidelberg, Germany
- Year and Date
  2012-07-08
- Data Source
  KAKENHI-PROJECT-12J03338
[Presentation] MAPK経路におけるシグナル遡及効果の数理モデル2010
- Author(s)
  平島剛志, Yoosik Kim, Stanislav Y.Shvartsman
- Organizer
  日本数理生物学会第20回大会
- Place of Presentation
  北海道大学
- Year and Date
  2010-09-15
- Data Source
  KAKENHI-PROJECT-09J03815
[Presentation] The signaling properties on ERK cyclic pathway are modulated by its downstream substrates2010
- Author(s)
  Tsuyoshi Hirashima, Yoosik Kim, Stanislav Y.Shvartsman
- Organizer
  A Joint Meeting with the Japanese Society of Developmental Biologists
- Place of Presentation
  Albuquerque Convention Center, Albuquerque, NM, USA
- Year and Date
  2010-08-08
- Data Source
  KAKENHI-PROJECT-09J03815
[Presentation] Mechanisms for Split Localization of Fgf10 Observed in Lung Bud Branching2009
- Author(s)
  平島剛志
- Organizer
  International Conference on Mathematical Biology and Annual Meeting of The Society for Mathematical Biology.
- Place of Presentation
  バンクーバー・カナダ
- Data Source
  KAKENHI-PROJECT-09J03815
[Presentation] Mechanisms for Split Localization of Fgf10 Observed in Lung Bud Branching2009
- Author(s)
  平島剛志
- Organizer
  日本発生生物学会第42回大会
- Place of Presentation
  新潟
- Data Source
  KAKENHI-PROJECT-09J03815

1. 松田道行 (10199812)

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2. 隅山健太 (00370114)

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3. 築地真也 (40359659)

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4. 平塚拓也 (90641639)

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5. 細川陽一郎

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HIRASHIMA TSUYOSHI 平島 剛志

Research Projects

Research Products

Co-Researchers

管径の恒常性維持に働く細胞力覚システムの応答特性の解明Principal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of a force-dependent mechanism for maintaining radial size of epithelial tubesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Live imaging of cell-to-cell communicationOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

分岐器官の形態形成過程における細胞運動の測定と数理モデリングResearch Fellow

Research Fellow

Project Period (FY)

Research Category

Research Field

Research Institution

分岐形態形成のダイナミックモデリングResearch Fellow

Research Fellow

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cellular Potts Modeling of Complex Multicellular Behaviors in Tissue Morphogenesis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vitro tubulogenesis of Madin-Darby canine kidney (MDCK) spheroids occurs depending on constituent cell number and scaffold gel concentration2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 上皮管組織の異方的な成長を支える協調的な多細胞動態と力学2016

Author(s)

Journal Title

Data Source

[Journal Article] Mathematical Study on Robust Tissue Pattern Formation in Growing Epididymal Tubule2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Procedures for the Quantification of Whole-Tissue Immunofluorescence Images Obtained at Single-Cell Resolution during Murine Tubular Organ Development2015

Author(s)

Journal Title

Publisher

DOI

PMID

Year and Date

Language

Data Source

[Journal Article] On Fundamental Cellular Processes for Emergence of Collective Epithelial Movement.2013

Author(s)

Journal Title

Data Source

[Journal Article] Cellular Potts Model on Collective Cell Movement.2013

Author(s)

Journal Title

Data Source

[Journal Article] Cellular Potts Model on Collective Cell Movement2013

Author(s)

Journal Title

Data Source

[Journal Article] On fundamental cellular processes for emergence of collective epithelial movement2013

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A Kinetic Model of ERK Cyclic Pathway on Substrate Control.2012

HIRASHIMA TSUYOSHI 平島剛志