INAOKA Ken Daniel 稲岡健ダニエル

… Alternative Names

INAOKA KEN DANIEL 稲岡健ダニエル

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Researcher Number	10623803
Other IDs
Affiliation (Current)	2025: 長崎大学, 熱帯医学研究所, 教授
Affiliation (based on the past Project Information) *help	2019 – 2024: 長崎大学, 熱帯医学研究所, 准教授 2023: 長崎大学, 熱帯医学研究所, 教授 2016 – 2018: 長崎大学, 熱帯医学・グローバルヘルス研究科, 助教 2014 – 2016: 東京大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator Basic Section 49040:Parasitology-related / Parasitology (including sanitary zoology) / Tumor biology Except Principal Investigator Basic Section 49050:Bacteriology-related / Medium-sized Section 62:Applied informatics and related fields / Basic Section 49040:Parasitology-related / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields / Functional biochemistry / Parasitology (including sanitary zoology)
Keywords	Principal Investigator 寄生虫 / 創薬 / ミトコンドリア / 呼吸鎖 / 構造生物学 / 生化学 / 感染現象 / 硫化水素代謝 / 住血吸虫 / 環境適応 … More / イオウ代謝 / 細胞小器官 / 細胞内寄生 / トリパノソーマ科原虫 / グリコソーム / Ateam / MaLion / ATeam / トリパノソーマ原虫 / 代謝 / FRET / ATPバイオセンサー / ATEAM / ATP動態 / バイオセンサー / エネルギー代謝 / 特殊環境 / 生体分子 / 蛋白質 / 酵素 / 感染症 / 寄生虫学 / ミトコンドリア様オルガネラ / 結晶構造解析 / 生化学的解析 / ASCT / ATP合成 / ケミカルバイオロジー / 新規薬剤標的 / ピリミジン生合成経路 / フマル酸呼吸 / 癌微小環境 … More Except Principal Investigator ミトコンドリア / X線結晶構造解析 / リンゴ酸・キノン酸化還元酵素 (MQO) / リンゴ酸脱水素酵素(MDH) / リンゴ酸代謝 / カンピロバクター / 自動合成 / ロボット / 抗規制原虫薬 / AI創薬 / 寄生原虫 / 分子動力学シミュレーション / 創薬 / スーパーコンピュータ / IT創薬 / 機械学習 / バイオインフォマティクス / ケモインフォマティクス / 翻訳 / アフィニティ精製 / リボソームタンパク質 / ミトコンドリアリボソーム / TAP法 / 翻訳機構 / リボソーム / マラリア原虫 / 代謝経路 / 代謝 / 代替経路 / 酸化的リン酸化 / 呼吸鎖 / ミトコンドリア病 / 低酸素 / ミトコンドリア呼吸鎖 / 海産線虫 / 底生線虫 / 呼吸鎖機能 / 低酸素適応 / 嫌気呼吸 / 貧酸素適応 / 自由生活性線虫 / 結晶構造解析 / 薬剤標的分子 / フラボプロテイン / 酵素の触媒機構 / ユビキノン / 基質結合部位 / 阻害剤 / 共結晶 / ユビキノン結合部位 / NADH dehydrogenase / シアン耐酸化酵素 / 生合成 / アスコフラノン / トリパノソーマ / シアン耐性酸化酵素 Less

Drug development targeting Campylobacter's malate metabolic pathway
- Principal Investigator
  
  志波智生
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49050:Bacteriology-related
- Research Institution
  Kyoto Institute of Technology
Investigation of sulfide metabolism pathway from Schistosoma mansoniPrincipal Investigator
- Principal Investigator
  
  稲岡健ダニエル
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Nagasaki University
A study on a low-cost translation mechanism in the mitochondrial ribosome of the malaria parasite
- Principal Investigator
  
  Hikosaka Kenji
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Chiba University
Development of an in silico and Robotic-Assisted Drug Discovery System and Its Application to the Search for Therapeutic Agents against Chagas Disease
- Principal Investigator
  
  Masakazu Sekijima
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 62:Applied informatics and related fields
- Research Institution
  Tokyo Institute of Technology
Imaging the ATP metabolism in Trypanosoma cruzi intracellular amastigotesPrincipal Investigator
- Principal Investigator
  
  Inaoka Ken Daniel
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49040:Parasitology-related
- Research Institution
  Nagasaki University
Insights on the mechanism of mitochondrial diseases
- Principal Investigator
  
  Kita Kiyoshi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Nagasaki University
Adaptation of free living marine nematode to deoxygenation: comparative study of nematode mitochondrial respiratory chain
- Principal Investigator
  
  WADA Minoru
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 40:Forestry and forest products science, applied aquatic science, and related fields
- Research Institution
  Nagasaki University
Molecular basis of ATP synthesis machinery from parasite living under microenvironmentPrincipal Investigator
- Principal Investigator
  
  INAOKA Ken Daniel
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Nagasaki University
Study on the reaction mechanism of type II NADH dehydrogenase by structural and biochemical analyses of the enzyme-inhibitor interaction.
- Principal Investigator
  
  Yamashita Tetsuo
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Functional biochemistry
- Research Institution
  Kagawa University
Chemical biology of cyanide-insensitive Trypanosome alternative oxidase.
- Principal Investigator
  
  KITA Kiyoshi
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Parasitology (including sanitary zoology)
- Research Institution
  Nagasaki University
  The University of Tokyo
Pyrimidine biosynthesis and energy metabolism in cancer microenvironmentPrincipal Investigator
- Principal Investigator
  
  INAOKA KEN DANIEL
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  The University of Tokyo

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation Book Patent Other

[Book] Kala Azar in South Asia2017
- Author(s)
  Nozomu Nihashi, Daniel Ken Inaoka, Chiaki Tsuge, Emmanuel Oluwadare Balogun, Yasutaka Osada, Yasuyuki Goto, Yoshitsugu Matsumoto, Takeshi Nara, Tatsushi Mogi, Shigeharu Harada, Kita Kiyoshi
- Total Pages
  309
- Publisher
  Springer International Publishing
- Data Source
  KAKENHI-PROJECT-26253025
[Book] Cytochrome Complexes:Evolution, Structures, Energy Transduction, and Signaling2016
- Author(s)
  Luke Young, Benjamin May, Tomoo Shiba, Shigeharu Harada, Daniel Ken Inaoka, Kiyoshi Kita, Anthony L. Moore
- Total Pages
  739
- Publisher
  Springer Netherlands
- Data Source
  KAKENHI-PROJECT-26253025
[Journal Article] Fumarate respiration of Fasciola flukes as a potential drug target2024
- Author(s)
  Tashibu Atsushi、Inaoka Daniel Ken、Sakamoto Kimitoshi、Murakami Kenji、Zannatul Ferdoush、Kita Kiyoshi、Ichikawa-Seki Madoka
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 13 Pages: 1302114-1302114
- DOI
  10.3389/fcimb.2023.1302114
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K05954, KAKENHI-PROJECT-20H00620
[Journal Article] Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni2023
- Author(s)
  Kabongo Augustin Tshibaka、Acharjee Rajib、Sakura Takaya、Bundutidi Gloria Mavinga、Hartuti Endah Dwi、Davies Cadi、Gundogdu Ozan、Kita Kiyoshi、Shiba Tomoo、Inaoka Daniel Ken
- Journal Title
  
  Frontiers in Molecular Biosciences
  
  Volume: 10 Pages: 1095026-1095026
- DOI
  10.3389/fmolb.2023.1095026
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-20H00620
[Journal Article] Discovery of a Hidden Trypanosoma cruzi Spermidine Synthase Binding Site and Inhibitors through In Silico, In Vitro, and X-ray Crystallography2023
- Author(s)
  Yoshino Ryunosuke、Yasuo Nobuaki、Hagiwara Yohsuke、Ishida Takashi、Inaoka Daniel Ken、Amano Yasushi、Tateishi Yukihiro、Ohno Kazuki、Namatame Ichiji、Niimi Tatsuya、Orita Masaya、Kita Kiyoshi、Akiyama Yutaka、Sekijima Masakazu
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 29 Pages: 25850-25860
- DOI
  10.1021/acsomega.3c01314
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H00620
[Journal Article] Siccanin is a dual-target inhibitor of Plasmodium falciparum mitochondrial complex II and complex III.2022
- Author(s)
  Komatsuya K, Sakura T, Shiomi K, Omura S, Hikosaka K, Nozaki T, Kita K, Inaoka DK.
- Journal Title
  
  Pharmaceuticals
  
  Volume: 15 Issue: 7 Pages: 903-903
- DOI
  10.3390/ph15070903
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07520, KAKENHI-PROJECT-22K07045, KAKENHI-PROJECT-20K07461
[Journal Article] Identification of 3,4-Dihydro-2H,6H-pyrimido[1,2-c][1,3]benzothiazin-6-imine Derivatives as Novel Selective Inhibitors of Plasmodium falciparum Dihydroorotate Dehydrogenase2021
- Author(s)
  Hartuti Endah Dwi、Sakura Takaya、Tagod Mohammed S. O.、Yoshida Eri、Wang Xinying、Mochizuki Kota、Acharjee Rajib、Matsuo Yuichi、Tokumasu Fuyuki、Mori Mihoko、Waluyo Danang、Shiomi Kazuro、Nozaki Tomoyoshi、Hamano Shinjiro、Shiba Tomoo、Kita Kiyoshi、Inaoka Daniel Ken
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 13 Pages: 7236-7236
- DOI
  10.3390/ijms22137236
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436
[Journal Article] Biochemical Studies of Mitochondrial Malate: Quinone Oxidoreductase from Toxoplasma gondii2021
- Author(s)
  Acharjee Rajib、Talaam Keith、Hartuti Endah、Matsuo Yuichi、Sakura Takaya、Gloria Bundutidi、Hidano Shinya、Kido Yasutoshi、Mori Mihoko、Shiomi Kazuro、Sekijima Masakazu、Nozaki Tomoyoshi、Umeda Kousuke、Nishikawa Yoshifumi、Hamano Shinjiro、Kita Kiyoshi、Inaoka Daniel
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Issue: 15 Pages: 7830-7830
- DOI
  10.3390/ijms22157830
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-18KK0454, KAKENHI-PROJECT-20H00620, KAKENHI-PROJECT-19H03436
[Journal Article] Weak O2 binding and strong H2O2 binding at the non-heme diiron center of Trypanosome Alternative Oxidase2021
- Author(s)
  S.Yamasaki, M.Shoji, M.Kayanuma, V.Sladek, D.K.Inaoka, Y.Matsuo, T.Shiba, L.Young, A.L.Moore, K.Kita, Y.Shigeta
- Journal Title
  
  Biochimica et Biophysica Acta - Bioenergetics
  
  Volume: 1862 Issue: 4 Pages: 148356-9
- DOI
  10.1016/j.bbabio.2020.148356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-20H05088, KAKENHI-PLANNED-20H05453, KAKENHI-PROJECT-19K07523, KAKENHI-PUBLICLY-20H05497, KAKENHI-PROJECT-19H03436
[Journal Article] Mitochondria as a Potential Target for the Development of Prophylactic and Therapeutic Drugs against Schistosoma mansoni Infection2021
- Author(s)
  Talaam Keith Kiplangat、Inaoka Daniel Ken、Hatta Takeshi、Tsubokawa Daigo、Tsuji Naotoshi、Wada Minoru、Saimoto Hiroyuki、Kita Kiyoshi、Hamano Shinjiro
- Journal Title
  
  Antimicrobial Agents and Chemotherapy
  
  Volume: 65 Issue: 10
- DOI
  10.1128/aac.00418-21
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436, KAKENHI-PROJECT-21K06996, KAKENHI-PROJECT-17H01684, KAKENHI-PROJECT-21H04852
[Journal Article] Structural and Biochemical Features of Eimeria tenella Dihydroorotate Dehydrogenase, a Potential Drug Target2020
- Author(s)
  Sato D, Hartuti ED, Inaoka DK, Sakura T, Amalia E, Nagahama M, Yoshioka Y, Tsuji N, Nozaki T, Kita K, Harada S, Matsubayashi M, Shiba T.
- Journal Title
  
  Genes (Basel)
  
  Volume: 11(12) Issue: 12 Pages: 1468-1468
- DOI
  10.3390/genes11121468
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19K16719
[Journal Article] The ASCT/SCS cycle fuels mitochondrial ATP and acetate production in Trypanosoma brucei.2020
- Author(s)
  Mochizuki K, Inaoka DK, Mazet M, Shiba T, Fukuda K, Kurasawa H, Millerioux Y, Boshart M, Balogun EO, Harada S, Hirayama K, Bringaud F, Kita K.
- Journal Title
  
  Biochim Biophys Acta Bioenerg
  
  Volume: 1861(11) Issue: 11 Pages: 148283-148283
- DOI
  10.1016/j.bbabio.2020.148283
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07523, KAKENHI-PROJECT-19H03436
[Journal Article] Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region2020
- Author(s)
  Adamu Auwal、Jada Mahmoud Suleiman、Haruna Hauwa Mohammed Sani、Yakubu Bassa Obed、Ibrahim Mohammed Auwal、Balogun Emmanuel Oluwadare、Sakura Takaya、Inaoka Daniel Ken、Kita Kiyoshi、Hirayama Kenji、Culleton Richard、Shuaibu Mohammed Nasir
- Journal Title
  
  Malaria Journal
  
  Volume: 19 Issue: 1
- DOI
  10.1186/s12936-020-03506-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Journal Article] Complete biosynthetic pathways of ascofuranone and ascochlorin in Acremonium egyptiacum2019
- Author(s)
  Araki Yasuko、Awakawa Takayoshi、Matsuzaki Motomichi、Cho Rihe、Matsuda Yudai、Hoshino Shotaro、Shinohara Yasutomo、Yamamoto Masaichi、Kido Yasutoshi、Inaoka Daniel Ken、Nagamune Kisaburo、Ito Kotaro、Abe Ikuro、Kita Kiyoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 未定 Issue: 17 Pages: 8269-8274
- DOI
  10.1073/pnas.1819254116
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15679, KAKENHI-PLANNED-16H06443, KAKENHI-PROJECT-16J01117, KAKENHI-PROJECT-18KK0454, KAKENHI-PUBLICLY-19H04641, KAKENHI-PROJECT-19H03436, KAKENHI-PROJECT-17H04763, KAKENHI-PROJECT-17KT0095
[Journal Article] Ubiquinone binding site of yeast NADH dehydrogenase revealed by structures binding novel competitive- and mixed-type inhibitors2018
- Author(s)
  Yamashita Tetsuo, Inaoka Daniel Ken, Shiba Tomoo, Oohashi Takumi, Iwata So, Yagi Takao, Kosaka Hiroaki, Miyoshi Hideto, Harada Shigeharu, Kita Kiyoshi, Hirano Katsuya
- Journal Title
  
  Scientific Reports
  
  Volume: 8 Issue: 1 Pages: 2427-2427
- DOI
  10.1038/s41598-018-20775-6
- NAID
  120006532084
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17F17420, KAKENHI-PROJECT-15K07005
[Journal Article] In silico, in vitro, X-ray crystallography, and integrated strategies for discovering spermidine synthase inhibitors for Chagas disease2017
- Author(s)
  Yoshino Ryunosuke、Yasuo Nobuaki、Hagiwara Yohsuke、Ishida Takashi、Inaoka Daniel Ken、Amano Yasushi、Tateishi Yukihiro、Ohno Kazuki、Namatame Ichiji、Niimi Tatsuya、Orita Masaya、Kita Kiyoshi、Akiyama Yutaka、Sekijima Masakazu
- Journal Title
  
  Scientific Reports
  
  Volume: 7 Issue: 1 Pages: 1-9
- DOI
  10.1038/s41598-017-06411-9
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H02776, KAKENHI-PROJECT-17H01814, KAKENHI-PROJECT-16J09021, KAKENHI-PROJECT-15K16082, KAKENHI-PROJECT-16K19114
[Journal Article] Design and Synthesis of Potent Substrate-based Inhibitors of the Trypanosoma cruzi Dihydroorotate Dehydrogenase2017
- Author(s)
  D. K. Inaoka, M. Iida, S. Hashimoto, T. Tabuchi,T. Kuranaga, E. O. Balogun, T. Honma, A. Tanaka, S. Harada, T. Nara, K. Kita, M. Inoue
- Journal Title
  
  Bioorg. Med. Chem.
  
  Volume: 25 Issue: 4 Pages: 1465-1470
- DOI
  10.1016/j.bmc.2017.01.009
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01130, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J12403, KAKENHI-PROJECT-16K15268
[Journal Article] Glycerol kinase of African trypanosomes possesses an intrinsic phosphatase activity2017
- Author(s)
  Balogun Emmanuel Oluwadare、Inaoka Daniel Ken、Shiba Tomoo、Tokuoka Suzumi M.、Tokumasu Fuyuki、Sakamoto Kimitoshi、Kido Yasutoshi、Michels Paul A.M.、Watanabe Yoh-Ichi、Harada Shigeharu、Kita Kiyoshi
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - General Subjects
  
  Volume: 1861 Issue: 11 Pages: 2830-2842
- DOI
  10.1016/j.bbagen.2017.07.028
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K15679, KAKENHI-PROJECT-16K19114
[Journal Article] Discovery of New Class of Trypanocidal Compounds Targeting the Energy Metabolism of African Trypanosomes2017
- Author(s)
  Balogun Emmanuel Oluwadare、Inaoka Daniel Ken、Shiba Tomoo、Watanabe Yoh-Ichi、Moore Anthony、Harada Shigeharu、Kita Kiyoshi
- Journal Title
  
  Open Forum Infect. Dis.
  
  Volume: 4 Issue: suppl_1 Pages: S121-S121
- DOI
  10.1093/ofid/ofx163.154
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Journal Article] Expression, purification, and crystallization of type 1 isocitrate dehydrogenase from Trypanosoma brucei brucei2017
- Author(s)
  Wang Xinying、Inaoka Daniel Ken、Shiba Tomoo、Balogun Emmanuel Oluwadare、Allmann Stefan、Watanabe Yoh-ichi、Boshart Michael、Kita Kiyoshi、Harada Shigeharu
- Journal Title
  
  Protein Expr. Purif.
  
  Volume: 138 Pages: 56-62
- DOI
  10.1016/j.pep.2017.06.011
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Journal Article] Conjugates of 2,4-Dihydroxybenzoate and Salicylhydroxamate and Lipocations Display Potent Antiparasite Effects by Efficiently Targeting the Trypanosoma brucei and Trypanosoma congolense Mitochondrion.2017
- Author(s)
  Francisco Jose Fueyo Gonzalez, Godwin U. Ebiloma, Carolina Izquierdo Garcia, Victor Bruggeman, Jose Maria Sanchez Villamanan, Anne Donachie, Emmanuel Oluwadare Balogun, Daniel Ken Inaoka, Tomoo Shiba, Shigeharu Harada, Kiyoshi Kita, Harry P. de Koning, Christophe Dardonville
- Journal Title
  
  Journal of Medicinal Chemistry
  
  Volume: 60(4) Issue: 4 Pages: 1509-1522
- DOI
  10.1021/acs.jmedchem.6b01740
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-26440027
[Journal Article] Investigation into the ubiquinol-binding site of the trypanosomal alternative oxidase2016
- Author(s)
  Benjamin May, Luke Young, Mary Albury, Daniel Ken Inaoka, Kiyoshi Kita, Anthony L. Moore
- Journal Title
  
  Biochimica et Biophysica Acta (BBA)-Bioenergetics
  
  Volume: 1857 Pages: e41-e41
- DOI
  10.1016/j.bbabio.2016.04.309
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26253025
[Journal Article] The Open Form Inducer Approach for Structure-Based Drug Design2016
- Author(s)
  D. K. Inaoka, M. Iida, T. Tabuchi, T. Honma, N. Lee, S. Hashimoto, S. Matsuoka, T. Kuranaga, K. Sato, T. Shiba, K. Sakamoto, E. O. Balogun, S. Suzuki, T. Nara, J. R. Rocha, C. A. Montanari, A. Tanaka, M. Inoue, K. Kita, S. Harada
- Journal Title
  
  PLoS ONE
  
  Volume: 11 Issue: 11 Pages: e0167078-e0167078
- DOI
  10.1371/journal.pone.0167078
- NAID
  120006987593
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01130, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15J12403, KAKENHI-PROJECT-26304041, KAKENHI-PROJECT-26460504, KAKENHI-PROJECT-16K15268
[Journal Article] Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method2015
- Author(s)
  Ryunosuke Yoshino, Nobuaki Yasuo, Daniel Ken Inaoka, Yohsuke Hagiwara, Kazuki Ohno, Masaya Orita, Masayuki Inoue, Tomoo Shiba, Shigeharu Harada, Teruki Honma, Emmanuel Oluwadare Balogun, Josmar Rodrigues Da Rocha, Carlos Alberto Montanari, Kiyoshi Kita, Masakazu Sekijima
- Journal Title
  
  PLoS One
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870119
[Journal Article] 1.Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria2015
- Author(s)
  Inaoka DK, Shiba T, Sato D, Balogun EO, Sasaki T, Nagahama M, Oda M, Matsuoka S, Ohmori J, Honma T, Inoue M, Kita K, Harada S
- Journal Title
  
  Int. J. Mol. Sci.
  
  Volume: 16 Issue: 7 Pages: 15287-15308
- DOI
  10.3390/ijms160715287
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440027, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26870119
[Journal Article] Structural Insights into the Molecular Design of Flutolanil Derivatives Targeted for Fumarate Respiration of Parasite Mitochondria2015
- Author(s)
  Daniel Ken Inaoka, Tomoo Shiba, Dan Sato, Emmanuel Oluwadare Balogun, Tsuyoshi Sasaki, Madoka Nagahama, Masatsugu Oda, Shigeru Matsuoka, Junko Ohmori, Teruki Honma, Masayuki Inoue, Shigeharu Harada, and Kiyoshi Kita
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 印刷中
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26870119
[Journal Article] 2.Pharmacophore Modeling for Anti-Chagas Drug Design Using the Fragment Molecular Orbital Method2015
- Author(s)
  Yoshino R, Yasuo N, Inaoka DK, Hagiwara Y, Ohno K, Orita M, Inoue M, Shiba T, Harada S, Honma T, Balogun EO, da Rocha JR, Montanari CA, Kita K, Sekijima M
- Journal Title
  
  PLoS One
  
  Volume: 10 Issue: 5 Pages: 1-15
- DOI
  10.1371/journal.pone.0125829
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26440027, KAKENHI-PROJECT-24240044, KAKENHI-PROJECT-26253003, KAKENHI-PROJECT-26253025, KAKENHI-PROJECT-15H02776, KAKENHI-PROJECT-26870119
[Patent] 駆虫剤2014
- Inventor(s)
  北　潔、稲岡　健ダニエル、山本　雅一
- Industrial Property Rights Holder
  北　潔、稲岡　健ダニエル、山本　雅一
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-17
- Acquisition Date
  2015-04-23
- Overseas
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Understanding the mechanism of adaptation to environmental sulfide by Schistosoma mansoni2024
- Author(s)
  Ken Daniel Inaoka
- Organizer
  U.S.-Japan Cooperative Medical Sciences Program (USJCMSP) U.S -Japan Parasitic Diseases Joint Panel Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] Expression of an active ASCT/SCS cycle in Mycobacterium smegmatis confers resistance to Bedaquiline2023
- Author(s)
  Mavinga Gloria Bundutidi, Ando Yuri, Matsuo Yuichi, Hayashishita Mizuki, Mochizuki Kota, Cook Gregory M., Sekijima Masakazu, Sakura Takaya, Hamano Shinjiro, Hirayama Kenji, Kita Kiyoshi, Ken Daniel Inaoka
- Organizer
  Gordon Research Conferences on Bioenergetics, Proctor Academy, New Hampshire
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] The trypanosome alternative oxidase as a target for drug development2023
- Author(s)
  Ken Daniel Inaoka
- Organizer
  Seminars in Pharmasciences
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] Structural insights into SCOT activity of TbASCT-D62N mutant2023
- Author(s)
  Ken Daniel Inaoka, Mochizuki Kota, Balogun Emmanuel O., Fukuda Keisuke, Kurasawa Hana, Shiba Tomoo, Harada Shigeharu, Maze Muriel, Millerioux Yoann, Bringaud Frederic, Boshar Michael, Hirayama Kenji, Kita Kiyoshi
- Organizer
  11th Meeting GlycoNov/AdipoTryp
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] Sulfide:quinone oxidoreductase from Schistosoma mansoni forms a long-lived charge transfer complex2023
- Author(s)
  Ken Daniel Inaoka
- Organizer
  International Meeting of the Italian Group of Biomembranes and Bioenergetics (GIBB)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] Characterization of sufite oxidase from the intestinal parasite Schistosoma mansoni2023
- Author(s)
  Ken Daniel Inaoka
- Organizer
  第14回蠕虫研究会
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] マンソン住血吸虫由来sulfite oxidaseの解析2023
- Author(s)
  稲岡　健ダニエル
- Organizer
  2023年度ミトコンドリア・サイエンス・ワークショップ（MSW2023）
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] マンソン住血吸虫sulfite oxidaseの生化学的解析2023
- Author(s)
  稲岡　健ダニエル
- Organizer
  第96回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] 寄生虫の代謝と創薬2023
- Author(s)
  稲岡　健ダニエル
- Organizer
  2022年度日本医学会連合Rising Starリトリート
- Invited
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] Characterization of sufite oxidase from Schistosoma mansoni2023
- Author(s)
  稲岡　健ダニエル
- Organizer
  日本生体エネルギー研究会・第49回討論会
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] マンソン住血吸虫ミトコンドリアに局在する亜硫酸オキシダーゼの解析2023
- Author(s)
  稲岡　健ダニエル
- Organizer
  第29回分子寄生虫学ワークショップ第19回分子寄生虫・マラリア研究フォーラム合同大会
- Data Source
  KAKENHI-PROJECT-23K27402
[Presentation] Trypanosomal ASCT and alternative oxidase as tools to study Mycobacterium bioenergetics2023
- Author(s)
  Mavinga Gloria Bundutidi, Ando Yuri, Matsuo Yuichi, Hayashishita Mizuki, Mochizuki Kota, Cook Gregory M., Sekijima Masakazu, Sakura Takaya, Hamano Shinjiro, Hirayama Kenji, Kita Kiyoshi, Ken Daniel Inaoka
- Organizer
  11th Meeting GlycoNov/AdipoTryp
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] Challenges in isolation of mitochondrial ribosomes from the malaria parasite2022
- Author(s)
  Xioxia Lin, Hirokazu Sakamoto, Rie Kubota, Yoh-Ichi Watanabe, Daniel Ken Inaoka, Naoaki Shinzawa, Kenji Hikosaka
- Organizer
  第92回日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-20K07461
[Presentation] EXPRESSION OF TRYPANOSOMAL ACETATE: SUCCINATE COA TRANSFERASE IS SUFFICIENT TO DEVELOP RESISTANCE TO THE ATP SYNTHASE INHIBITOR BEDAQUILINE IN MYCOBACTERIUM SMEGMATIS2022
- Author(s)
  Bundutidi M. G, Ando Y., Matsuo Y., Nakatani Y., Kiel H., Cook G. M., Sakura T., Hamano S, Hirayama K. and Kita K., Inaoka D. K.
- Organizer
  Spring School “Trypanosomatid Metabolism” 10th Meeting GLYCONOV/ADIPOTRYP
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] 酵母細胞質型ジヒドロオロト酸脱水素酵素遺伝子を導入したげっ歯類マラリア原虫のアトバコン耐性発現パターンの解析2022
- Author(s)
  陳雪、新倉保、坂本寛和、佐倉孝哉、稲岡ダニエル健、彦坂健児
- Organizer
  第92回日本寄生虫学会
- Data Source
  KAKENHI-PROJECT-20K07461
[Presentation] 寄生原虫 Trypanosoma 由来エネルギー代謝酵素を用いた代替エネルギー代謝経路の構築とミトコンドリア病研究への応用2021
- Author(s)
  林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
- Organizer
  日本生体エネルギー研究会第47回討論会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Co-crystal structure analysis of Ferulenol derivatives in complex with human dihydroorotate dehydrogenase: a therapeutic target for cancer cells living under tumor microenvironment2021
- Author(s)
  Mohammed S. O. Tagod, Takaya Sakura, Eri Amalia, Takahiro Sasagawa, Osumi Yukiko, Matsui Hiroki, Masuda Ayuna, Yukiko Miyazaki, Tomoo Shiba, Hiroyuki Saimoto, Kiyoshi Kita, Daniel Ken Inaoka
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Biochemical studies of mitochondrial malate:quinone oxidoreductase from Toxoplasma gondii2021
- Author(s)
  Acharjee R., Talaam K. K., Hartuti E. D., Matsuo Y., Sakura T., Gloria B. M., Hidano S., Kido Y., Mori M., Shiomi K., Sekijima M., Nozaki T., Umeda K., Nishikawa Y., Hamano S., Kita K. and Inaoka D. K.
- Organizer
  日本生体エネルギー研究会第47回討論会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Expression of trypanosomal acetate: succinate CoA transferase is sufficient to develop resistance to the ATP synthase inhibitor bedaquiline in Mycobacterium smegmatis2021
- Author(s)
  Bundutidi M. G, Ando Y., Matsuo Y., Nakatani Y., Kiel H., Cook G. M., Sakura T., Hamano S., Hirayama K. and Kita K., Inaoka D. K.
- Organizer
  日本生体エネルギー研究会第47回討論会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 寄生原虫トリパノソーマ由来エネルギー代謝因子を用いたミトコンドリア呼吸鎖機能破綻の解析2021
- Author(s)
  林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Characterization of putative sulfide:quinone oxidoreductase from an intestinal parasite Schistosoma mansoni2021
- Author(s)
  Talaam Keith Kiplangat, Yuichi Matsuo, Acharjee Rajib, Tetsuo Yamashita, Kawano Tetsuro, Endah Dwi Hartuti, Tomoyoshi Nozaki, Shinjiro Hamano, Kiyoshi Kita, and Daniel Ken Inaoka
- Organizer
  日本生体エネルギー研究会第47回討論会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 生薬を用いたクルーズトリパノソーマに対する新規抗原虫薬の探索研究2021
- Author(s)
  田山雄基、水上修作、當銘一文、小松かつ子、稲岡健ダニエル、平山謙二
- Organizer
  第90回日本寄生虫学会大会・第32回日本臨床寄生虫学会大会　合同大会
- Data Source
  KAKENHI-PROJECT-20H00620
[Presentation] Trypanosoma brucei由来シアン耐性酵素TAOのミトコンドリア病研究への応用2021
- Author(s)
  林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
- Organizer
  第九十回日本寄生虫学会・第三十二回日本臨床寄生虫学会・合同大会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Trypanosoma 由来エネルギー代謝因子を用いたミトコンドリア病発症機構の解明2020
- Author(s)
  林下瑞希、小笠原絵美、武田弘資、八谷早紀、稲岡健ダニエル、北潔
- Organizer
  日本生体エネルギー研究会　第46回討論会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 底生線虫の生理・生化学解析に向けた試料調製手法の検討2020
- Author(s)
  吉岡奈美、葭田遼介、伊藤尚斗、山口健一、稲岡健ダニエル、北潔、和田実
- Organizer
  令和2年度日本水産学会
- Data Source
  KAKENHI-PROJECT-18K19236
[Presentation] フィラリアのミトコンドリアを標的にした生化学的解析2019
- Author(s)
  望月恒太、稲岡健ダニエル、Zannatul Ferdoush、大森惇子、福本晋也、濱﨑めぐみ、濱野真二郎、平山健二、北潔
- Organizer
  第13回蠕虫研究会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] がん微小環境におけるピリミジン生合成経路2019
- Author(s)
  稲岡健ダニエル, 宮崎幸子, 志波智夫, 斎本博之, Amalia Eri, 城戸康年, 坂井千香, Moore Anthony L., 原田繁春, 北潔
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 寄生虫はどうやって高濃度硫化水素環境に適応しているのか？2019
- Author(s)
  稲岡健ダニエル、Talaam Keith Kiplangat、松尾祐一、川野哲郎、 Endah Dwi Hartuti、野崎智義、濱野真二郎、北潔
- Organizer
  第13回蠕虫研究会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 肝蛭のミトコンドリア呼吸鎖におけるPlumbaginの作用機序の解明2019
- Author(s)
  田渋敦士、関まどか、稲岡健ダニエル、麻田正仁、北潔
- Organizer
  第13回蠕虫研究会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] 回虫成虫複合体IIを標的にした特異的な抗線虫薬の創出2019
- Author(s)
  志波智生, 稲岡健ダニエル, 北潔, 原田繁春
- Organizer
  第92回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19H03436
[Presentation] Biochemical characterization, site-directed mutagenesis Acetate:succinate CoA transferase from Trypanosoma brucei and T. cruzi and identification of inhibitors2018
- Author(s)
  Kota Mochizuki, Daniel Ken Inaoka, Emmanuel O. Balogun, Tomoo Shiba, Shigeharu Harada, Frederic Bringaud, Kenji Hirayama and Kiyoshi Kita
- Organizer
  8th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Biochemical characterization of in vitro reconstituted Acetate:succinate CoA transferase/Succinyl-CoA synthetase cycle from Trypanosoma brucei and identification of inhibitors2018
- Author(s)
  Kota Mochizuki, Daniel Ken Inaoka, Emmanuel O. Balogun, Tomoo Shiba, Shigeharu Harada, Frederic Bringaud, Kenji Hirayama and Kiyoshi Kita
- Organizer
  The U.S.-Japan Cooperative Medical Science Program the 48th Joint Conference on Parasitic Diseases
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] シアン耐性呼吸を標的とした抗トリパノソーマ薬の臨床試験へむけて2018
- Author(s)
  城戸康年、稲岡健ダニエル、松崎素道、志波智生、原田繁春、斎本博之、山本雅一、上村尚人、北潔
- Organizer
  第87回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Glycerol kinase of African trypanosomes possess additional enzymatic activities that may aid to degrade potential toxic metabolites2018
- Author(s)
  Emmanuel O. Balogun, Daniel Ken Inaoka, Tomoo Shiba, Shigeharu Harada and Kiyoshi Kita
- Organizer
  8th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Insights into the quinol and dioxygen redox cycle of Trypanosome Alternative Oxidase2018
- Author(s)
  Daniel Ken Inaoka, Tomoo Shiba, Yasutoshi Kido, Hiroyuki Saimoto, Anthony L. Moore, Shigeharu Harada and Kiyoshi Kita
- Organizer
  8th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Trypanosoma brucei の Acetate:succinate CoA transferase/Succinyl-CoA synthetase サイクルの in vitro 再構築を用いた生化学的解析及び阻害剤探索2018
- Author(s)
  望月恒太、稲岡健ダニエル、Balogun O. Emmanuel、志波智生、原田繁春、Frederic Bringaud、平山謙二、北潔
- Organizer
  第87回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] 競合および混合阻害剤との共結晶構造解析により明らかとなった出芽酵母由来Type II NADH脱水素酵素のユビキノン結合部位2018
- Author(s)
  山下哲生，稲岡健ダニエル，志波智生，大橋匠，岩田想，矢木隆雄，三芳秀，原田繁春，北潔，平野勝也
- Organizer
  日本農芸化学会中四国支部第51回講演会
- Data Source
  KAKENHI-PROJECT-15K07005
[Presentation] Trypanosoma科原虫のAcetate:succinate CoA transferase /Succinyl-CoA Synthetaseサイクルの生化学的解析2017
- Author(s)
  望月恒太、稲岡ダニエル健、バロガンエマニュエル、志波智生、原田繁春、フレデリックブリンゴード、平山謙二、北潔
- Organizer
  生命科学系学会合同年次大会ConBio2017・第40回日本分子生物学会年会・第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] 抗トリパノソーマ薬アスコフラノンの臨床応用へむけた包括的薬剤開発2017
- Author(s)
  城戸康年、稲岡健ダニエル、松崎素道、志波智生、原田繁春、斎本博之、山本雅一、北潔
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Purification of Leishmania mexicana serine hydroxymethyltransferase and aldehyde dehydrogenase2017
- Author(s)
  Kota Mochizuki, Daniel Ken Inaoka, Frederic Bringaud, Kenji Hirayama and Kiyoshi Kita
- Organizer
  7th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] トリパノソーマ科原虫の ATP 産生と共役した酢酸：コハク酸 CoA 転移酵素とサクシニル CoA 転移酵素の構造生物学的な特徴2017
- Author(s)
  稲岡ダニエル健、バログンエマニュエル、鈴木重雄、志波智生、 Frederic Bringaud 、原田繁春、北潔
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Trypanosoma cruziのピリミジン代謝経路を構成するアスパラギン酸トランスカルバモイラーゼの構造生物学的研究生体エネルギー2017
- Author(s)
  早水僚一、志波智生、的場一晃、奈良武司、北潔、稲岡ダニエル健、原田繁春
- Organizer
  生命科学系学会合同年次大会ConBio2017・第40回日本分子生物学会年会・第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Trypanosoma科原虫のAcetate:succinate CoA transferase/Succinyl-CoA synthetaseサイクルのin vitro再構築及び生化学的解析と阻害剤探索2017
- Author(s)
  望月恒太、稲岡健ダニエル、Balogun O. Emmanuel、志波智生、原田繁春、Frederic Bringaud、平山謙二、北潔
- Organizer
  第70回日本寄生虫学会南日本支部大会・67回日本衛生動物学会南日本支部大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Structural insights into NAD+ and NADP+ recognition from Trypanosoma brucei Glycosomal Isocitrate Dehydrogenase2017
- Author(s)
  Xinying Wang、Daniel Ken Inaoka、Emmanuel O. Balogun、Nicole Ziebart、Stefan Allmann、Michael Boshart、Frederic Bringaud、志波智生、原田繁春、北潔
- Organizer
  第86回日本寄生虫学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] 多様な補酵素特異性を持つアフリカ型トリパノソーマのグリコソームに局在するイソクエン酸脱水素酵素2017
- Author(s)
  Xinying Wang、稲岡ダニエル健、Emmanuel O. Balogun、浜野文三江、Nicole Ziebart、Stefan Allmann、Michael Boshart、Frederic Bringaud、徳舛富由樹、志波智生、原田繁春、北潔
- Organizer
  生命科学系学会合同年次大会ConBio2017・第40回日本分子生物学会年会・第90回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] トリパノソーマ科原虫のミトコンドリアで行われるATP産生と共役した酢酸発酵2017
- Author(s)
  Daniel Ken Inaoka, Balogun O. Emmanuel, Mochizuki Kota, Shigeo Suzuki, Shiba Tomoo, Frederic Bringaud, Shigeharu Harada and Kiyoshi Kita
- Organizer
  ミトコンドリアサイエンスワークショップ2017
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Glycosomal metabolic enzyme Isocitrate Dehydrogenase from Trypanosoma brucei shows dual coenzyme specificity2017
- Author(s)
  Xinying Wang, Daniel Ken Inaoka, Emmanuel O. Balogun, Fumie Hamano, Nicole Ziebart, Stefan Allmann, Michael Boshart, Frederic Bringaud, Fuyuki Tokumasu, Tomoo Shiba, Shigeharu Harada and Kiyoshi Kita
- Organizer
  第 77 回日本寄生虫学会東日本支部大会
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Structural insights into mechanism of NADP+/NAD+ recognition by Trypanosoma brucei glycosomal isocitrate dehydrogenase2017
- Author(s)
  Xinying Wang, Daniel Ken Inaoka, Emmanuel O. Balogun, Nicole Ziebart, Stefan Allmann, Michael Boshart, Frederic Bringaud, Tomoo Shiba, Shigeharu Harada and Kiyoshi Kita
- Organizer
  7th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Additional enzymatic activities of glycerol kinase from Trypanosoma brucei2017
- Author(s)
  Emmanuel O. Balogun, Daniel Ken Inaoka, Tomoo Shiba, Yoh-Ichi Watanabe, Anthony Moore, Shigeharu Harada and Kiyoshi Kita
- Organizer
  7th Meeting ACETOTRYP/GLYCONOV
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] Biochemical and structural characterization of mitochondrial ATP-coupled acetate:succinate CoA transferase family from Trypanosomal parasites.2016
- Author(s)
  稲岡　健ダニエル
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  仙台国際センター（宮城県仙台市）
- Year and Date
  2016-09-25
- Data Source
  KAKENHI-PROJECT-16K19114
[Presentation] 結晶構造から見たフルトラニルおよびその誘導体化合物の回虫成虫複合体Ⅱに対する特異性2015
- Author(s)
  米愛加, 長濱まどか, 梅本亮, 山本京史, 佐藤暖, 志波智生, 稲岡ダニエル健, 福田智美, 織田雅次, 北潔, 原田繁春
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 寄生線虫類のミトコンドリア酸呼吸と宿主内微小環境適応。2015
- Author(s)
  稲岡ダニエル健, Ferdoush Zannatul, 大森淳子, 福田智美, 福本晋也, 福本真一郎, 志波智生, 原田繁春 , 北潔
- Organizer
  第２３回分子寄生虫学ワークショップ／第１３回分子寄生虫・マラリア研究フォーラム合同大会
- Place of Presentation
  帯広畜産大学
- Year and Date
  2015-08-30
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 抗エキノコックス薬剤標的としてのミトコンドリアのフマル酸呼吸2015
- Author(s)
  遠海重裕、稲岡　健ダニエル、大森惇子、坂本君年、入江陸夫、考口裕一、八木欣平、斎本博之、北潔
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 低酸素環境下で生息する回虫成虫複合体Ⅱの構造・機能相関と特異的阻害剤の開発2015
- Author(s)
  原田繁春、稲岡　ダニエル健、北潔
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 原虫ミトコンドリオンの酢酸代謝2015
- Author(s)
  稲岡ダニエル健、Emmanuel O. Balogun、鈴木重雄、志波智生、原田繁春、Frederic Bringaud、北潔
- Organizer
  YoungMito 2015
- Place of Presentation
  千葉・ホテルシーサイド一宮オーツカ
- Year and Date
  2015-07-09
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 線虫類のフマル酸呼吸と宿主内微小環境適応2015
- Author(s)
  Daniel Ken Inaoka , Zannatul Ferdoush, Ohmori Junko, Fukuda Tomomi, Shinya Fukumoto, Shinichiro Fukumoto, Shiba Tomoo, Harada Shigeharu and Kiyoshi Kita
- Organizer
  第38回日本分子生物学会年会・第88回日本生化学会大会　合同大会
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 犬糸状虫の生活環におけるミトコンドリア呼吸鎖の変動－成虫とミクロフィラリアの比較－2015
- Author(s)
  Daniel Ken Inaoka, Zannatul Ferdoush, Ohmori Junko, Fukumoto Shinya, Shinichiro Fukumoto and Kiyoshi Kita
- Organizer
  第9回蠕虫研究会
- Place of Presentation
  岩手・つなぎ温泉　清温荘
- Year and Date
  2015-07-17
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] 出芽酵母由来Type II NADH dehydrogenase (NDH-2)のユビキノン競合阻害剤との高分解能複合体構造解析2015
- Author(s)
  大橋拓未、稲岡ダニエル健、山下哲生、志波智生、岩田想、原田繁春、北潔
- Organizer
  日本生体エネルギー研究会　第41回討論会
- Place of Presentation
  東京大学医学部1号館講堂
- Year and Date
  2015-12-23
- Data Source
  KAKENHI-PROJECT-15K07005
[Presentation] トリパノソーマ科原虫ミトコンドリアのATP合成における酢酸代謝の役割。
- Author(s)
  稲岡ダニエル健、鈴木重雄、Emmanuel O. Balogun、原田繁春、Frédéric Bringaud、北潔
- Organizer
  日本生体エネルギー研究会、第４０回討論会
- Place of Presentation
  愛媛大学　南加記念ホール
- Year and Date
  2014-12-11 – 2014-12-13
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] ヒトミトコンドリアDHODHを標的とした分子創薬
- Author(s)
  Daniel Ken Inaoka、Hiroyuki Saimoto 、Shigeharu Harada 、Kiyoshi Kita
- Organizer
  第二回　YoungMito
- Place of Presentation
  大阪府箕面・みのお山荘「風の杜」
- Year and Date
  2014-05-22 – 2014-05-23
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Chemical validation of 12-subunits respiratory Complex II from Trypanosomatid as drug target
- Author(s)
  Daniel Ken Inaoka, Nozomu Nihashi, Chiaki Tsuge, Takeshi Nara, Shigeharu Harada, Kiyoshi Kita
- Organizer
  13th International Congress of Parasitology
- Place of Presentation
  Camino Real Hotel, Mexico City
- Year and Date
  2014-08-10 – 2014-08-15
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Structure-based design of potent and selective inhibitors against Trypanosoma cruzi dihydroorotate dehydrogenase
- Author(s)
  Daniel Ken Inaoka, Maiko Iida, Toshiyuki Tabuchi, 中15人、Kiyoshi Kita
- Organizer
  The Asia Hub for e-Drug Discovery Symposium
- Place of Presentation
  Chengdu, Sichuan, China
- Year and Date
  2014-09-11 – 2014-09-12
- Invited
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Dissociation constant (Kd) of Trypanosoma brucei alternative oxidase inhibitors and their trypanocidal activity
- Author(s)
  Daniel Ken Inaoka, Tomoo Shiba, Tsuge Chiaki, Chou Rihe, Gen Takahashi, Satoshi Ueda, Yasutoshi Kido, Emmanuel Oluwadare Balogun, Kimitoshi Sakamoto, Takeshi Nara, Teruki Honma, Akiko Tanaka, Masayuki Inoue, Hiroyuki Saimoto, Anthony Moore, Shigeharu Harada, Kiyoshi Kita
- Organizer
  第84回日本寄生虫学会大会
- Place of Presentation
  杏林大学三鷹キャンパス
- Year and Date
  2015-03-21 – 2015-03-22
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] ブタ回虫、ヘモンカスとディロフィラリアの成虫及びアニサキスのL3幼虫では嫌気的なミトコンドリア呼吸鎖が機能する
- Author(s)
  稲岡　ダニエル健、Zannatul Ferdoush、大森　惇子、福本晋也、福本　奈津子、二橋　望、福本　真一郎、辻　尚利、北　潔
- Organizer
  第8回蠕虫研究会
- Place of Presentation
  ホテル鹿の湯札幌定山渓
- Year and Date
  2014-09-06 – 2014-09-07
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Characterization of Eimeria tenella sporozoite mitochondria
- Author(s)
  稲岡ダニエル健、松林　誠、小松谷啓介、八田岳士、三好猛晴、磯部　尚、川原史也、山岸潤也、彦坂健児、佐藤暖、志波智生、原田繁春、辻　尚利、北　潔
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Eimeria tenellaスポロゾイト呼吸鎖の生化学的解析
- Author(s)
  稲岡ダニエル健、松林　誠、小松谷啓介、八田岳士、三好猛晴、磯部　尚、川原史也、山岸潤也、彦坂健児、佐藤暖、志波智生、原田繁春、辻　尚利、北　潔
- Organizer
  第22回分子寄生虫学ワークショップ／第12回分子寄生虫・マラリア研究フォーラム合同大会
- Place of Presentation
  帯広畜産大学・原虫病研究センター、PKホール
- Year and Date
  2014-08-31 – 2014-09-03
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Pyrimidine de novo biosynthesis under tumor microenvironment
- Author(s)
  Daniel Ken Inaoka, Yukiko Hirota, Takahiro Sasagawa, Eriko Tomitsuka, Chika Sakai, Hiroyuki Saimoto, Shigeharu Harada, Kiyoshi Kita
- Organizer
  第37回日本分子生物学会年会（ワークショップ）
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Invited
- Data Source
  KAKENHI-PROJECT-26870119
[Presentation] Eimeria tenella スポロゾイトのミトコンドリア精製法の確立と呼吸鎖酵素活性
- Author(s)
  松林　誠、稲岡ダニエル健、小松谷啓介、八田岳士、三好猛晴、磯部　尚、川原史也、山岸潤也、彦坂健児、佐藤暖、志波智生、原田繁春、北　潔、辻　尚利
- Organizer
  第157回日本獣医学会学術集会
- Place of Presentation
  北海道大学高等教育推進機構
- Year and Date
  2014-09-09 – 2014-09-12
- Data Source
  KAKENHI-PROJECT-26870119
[]

1. KITA Kiyoshi (90134444)

# of Collaborated Projects: 4 results

# of Collaborated Products: 39 results
2. HARADA Shigeharu (80156504)

# of Collaborated Projects: 3 results

# of Collaborated Products: 20 results
3. SAIMOTO Hiroyuki (20186977)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
4. SHIBA Tomoo (80401206)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
5. HONMA Teruki (10466039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. Yamashita Tetsuo (80444727)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. WADA Minoru (70292860)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
8. Hikosaka Kenji (30456933)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. Masakazu Sekijima (80371053)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
10. 山口健一 (90363473)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
11. 小笠原絵美 (70778274)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
12. 渡邊洋一 (90323568)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
13. 庄司満 (30339139)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 平山謙二 (60189868)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
15. 樺島祥介 (80260652)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 松永哲郎 (00723206)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. AKIYAMA Yutaka

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 井上将行

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
19. 城戸康年

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
20. 関まどか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
21. 庄司光男

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
22. 佐倉孝哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

INAOKA Ken Daniel 稲岡 健ダニエル

INAOKA KEN DANIEL 稲岡 健ダニエル

Research Projects

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Drug development targeting Campylobacter's malate metabolic pathway

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Investigation of sulfide metabolism pathway from Schistosoma mansoniPrincipal Investigator

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A study on a low-cost translation mechanism in the mitochondrial ribosome of the malaria parasite

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Development of an in silico and Robotic-Assisted Drug Discovery System and Its Application to the Search for Therapeutic Agents against Chagas Disease

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Imaging the ATP metabolism in Trypanosoma cruzi intracellular amastigotesPrincipal Investigator

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Insights on the mechanism of mitochondrial diseases

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Adaptation of free living marine nematode to deoxygenation: comparative study of nematode mitochondrial respiratory chain

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Molecular basis of ATP synthesis machinery from parasite living under microenvironmentPrincipal Investigator

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Study on the reaction mechanism of type II NADH dehydrogenase by structural and biochemical analyses of the enzyme-inhibitor interaction.

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Chemical biology of cyanide-insensitive Trypanosome alternative oxidase.

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Pyrimidine biosynthesis and energy metabolism in cancer microenvironmentPrincipal Investigator

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[Book] Kala Azar in South Asia2017

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[Book] Cytochrome Complexes:Evolution, Structures, Energy Transduction, and Signaling2016

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INAOKA Ken Daniel 稲岡健ダニエル

INAOKA KEN DANIEL 稲岡健ダニエル