SHIMOMURA Atsushi 下村淳

Researcher Number	10625841
Affiliation (based on the past Project Information) *help	2016 – 2017: 大阪大学, 医学系研究科, 助教 2012 – 2015: 大阪大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator General surgery Except Principal Investigator General surgery
Keywords	Principal Investigator 乳癌 / 家族性乳癌 / BRCA1 / BRCA2 / 変異保因者 Except Principal Investigator 乳癌 / 抗癌剤 / 分子標的薬 / 感受性予測 / cell cycle profiling … More / 術前化学療法 / pCR / 乳腺造影MRI / ctDNA / メチレーション / predictive factor / サブタイプ / 予後因子 / cCRとpCRの乖離 / 予測因子 / 造影ＭＲＩ / 造影MRI Less

Development of the prediction of pCR to neoadjuvant chemotherapy in breast cancer patients
- Principal Investigator
  
  KIM Seung Jin
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Management of breast cancer patients with BRCA1 or BRCA2 mutations.Principal Investigator
- Principal Investigator
  
  SHIMOMURA Atsushi
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University
Novel prediction diagnosis for personalized treatment of breast cancer
- Principal Investigator
  
  KIM Seung Jin
- Project Period (FY)
  2012 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General surgery
- Research Institution
  Osaka University

All 2017 2016 2015 2014 2013

All Journal Article Presentation

[Journal Article] Correlation of Methylated Circulating Tumor DNA With Response to Neoadjuvant Chemotherapy in Breast Cancer Patients2017
- Author(s)
  Takahashi Hiroyo、Kagara Naofumi、Tanei Tomonori、Naoi Yasuto、Shimoda Masafumi、Shimomura Atsushi、Shimazu Kenzo、Kim Seung Jin、Noguchi Shinzaburo
- Journal Title
  
  Clinical Breast Cancer
  
  Volume: 17
- DOI
  10.1016/j.clbc.2016.06.006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10052
[Journal Article] Prediction of pathological complete response to neoadjuvant chemotherapy by magnetic resonance imaging in breast cancer patients.2015
- Author(s)
  Michishita S, Kim SJ, Shimazu K, Sota Y, Naoi Y, Maruyama N, Kagara N, Shimoda M, Shimomura A, Noguchi S.
- Journal Title
  
  The Breast
  
  Volume: 24 Pages: 159-165
- DOI
  10.1016/j.breast.2015.01.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K10052
[Journal Article] Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer.2014
- Author(s)
  Sota Y, Naoi Y, Tsunashima R, Kagara N, Shimazu K, Maruyama N, Shimomura A, Shimoda M, Kishi K, Baba Y, Kim SJ, Noguchi S.
- Journal Title
  
  Ann Oncol.
  
  Volume: Jan;25(1) Pages: 100-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24591904
[Journal Article] Significance of TP53 mutations determined by next-generation "deep"sequencing in prognosis of estrogen receptor-positive breast cancer.2014
- Author(s)
  Uji K, Naoi Y, Kagara N, Shimoda M, Shimomura A, Maruyama N, Shimazu K, Kim SJ, Noguchi S.
- Journal Title
  
  Cancer Lett.
  
  Volume: Jan 1;342(1) Pages: 19-26
- DOI
  10.1016/j.canlet.2013.08.028
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591904
[Journal Article] Methylated DNA and high total DNA levels in the serum of patients with breast cancer following neoadjuvant chemotherapy are predictive of a poor prognosis.2014
- Author(s)
  Fujita N, Kagara N, Yamamoto N, Shimazu K, Shimomura A, Shimoda M, Maruyama , Naoi Y, Morimoto K, Oda N, Kim SJ, Noguchi S.
- Journal Title
  
  Oncology Letters
  
  Volume: 8 Pages: 397-403
- DOI
  10.3892/ol.2014.2068
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591904
[Journal Article] BRCA1 promoter methylation of normal breast epithelial cells as a possible precursor for BRCA1-methylated breast cancer.2014
- Author(s)
  Otani Y, Miyake T, Kagara N, Shimoda M, Naoi Y, Maruyama N, Shimomura A, Shimazu K, Kim SJ, Noguchi S.
- Journal Title
  
  Cancer Sci.
  
  Volume: Oct;105(10) Pages: 1369-76
- DOI
  10.1111/cas.12506
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-24591903
[Journal Article] Comparison of efficacy of 95-gene and 21-gene classifier (Oncotype DX) for prediction of recurrence in ER-positive and node-negative breast cancer patients.2013
- Author(s)
  Naoi Y1, Kishi K, Tsunashima R, Shimazu K, Shimomura A, Maruyama N, Shimoda M, Kagara N, Baba Y, Kim SJ, Noguchi S.
- Journal Title
  
  Breast Cancer Res Treat.
  
  Volume: 2013 Jul;140(2) Pages: 299-306
- DOI
  10.1007/s10549-013-2640-9
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24591904
[Presentation] 乳癌術前化学療法による乳房温存手術の適応拡大とバイオマーカーの検討2016
- Author(s)
  金　昇晋、島津研三、下村　淳、他
- Organizer
  第116回日本外科学会定期学術集会
- Place of Presentation
  大阪国際会議場・リーガロイヤルホテル大阪（大阪市）
- Year and Date
  2016-04-14
- Invited
- Data Source
  KAKENHI-PROJECT-15K10052

1. KIM Seung JIN (90346213)

# of Collaborated Projects: 3 results

# of Collaborated Products: 8 results
2. 多根井智紀 (80771518)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

SHIMOMURA Atsushi 下村 淳

Research Projects

Research Products

Co-Researchers

Development of the prediction of pCR to neoadjuvant chemotherapy in breast cancer patients

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Management of breast cancer patients with BRCA1 or BRCA2 mutations.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Novel prediction diagnosis for personalized treatment of breast cancer

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Correlation of Methylated Circulating Tumor DNA With Response to Neoadjuvant Chemotherapy in Breast Cancer Patients2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Prediction of pathological complete response to neoadjuvant chemotherapy by magnetic resonance imaging in breast cancer patients.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of novel immune-related signature for prediction of pathological complete response to neoadjuvant chemotherapy in human breast cancer.2014

Author(s)

Journal Title

Data Source

[Journal Article] Significance of TP53 mutations determined by next-generation "deep"sequencing in prognosis of estrogen receptor-positive breast cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Methylated DNA and high total DNA levels in the serum of patients with breast cancer following neoadjuvant chemotherapy are predictive of a poor prognosis.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BRCA1 promoter methylation of normal breast epithelial cells as a possible precursor for BRCA1-methylated breast cancer.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of efficacy of 95-gene and 21-gene classifier (Oncotype DX) for prediction of recurrence in ER-positive and node-negative breast cancer patients.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] 乳癌術前化学療法による乳房温存手術の適応拡大とバイオマーカーの検討2016

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

SHIMOMURA Atsushi 下村淳