Okuda Hiroshi 奥田博史

… Alternative Names

OKUDA Hiroshi 奥田博史

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Researcher Number	10629215
Other IDs	https://orcid.org/0000-0002-5747-8086
Affiliation (Current)	2025: 横浜市立大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2021 – 2024: 横浜市立大学, 医学部, 助教 2020: 国立研究開発法人国立がん研究センター, 研究所, 外来研究員 2017 – 2018: 国立研究開発法人国立がん研究センター, 研究所, 外来研究員 2016: 京都大学, 医学研究科, 特定助教 2014: 京都大学, 医学(系)研究科(研究院), 助教 2014: 京都大学, 医学研究科, 特定助教 2013: 京都大学, 医学(系)研究科(研究院), 研究員
Review Section/Research Field	Principal Investigator Hematology / Basic Section 49070:Immunology-related / Basic Section 54010:Hematology and medical oncology-related / Tumor biology Except Principal Investigator Hematology / Basic Section 54010:Hematology and medical oncology-related
Keywords	Principal Investigator 白血病 / がん / 転写 / AF4 / MLL / 発がん / 感染症 / 転写因子 / IRF8 / 分化制御 … More / 単球 / RNA結合タンパク質 / 発現制御 / MLL-AF4 / 癌 / MLL白血病 / AEP / SL1 … More Except Principal Investigator エピジェネティクス / 蛋白質 / 内科 / 生体分子 / 発現制御 / 癌 / 転写 / MLL / 白血病 / DNAメチル化 / 転写因子 / 樹状細胞 / 血球分化 / クロマチン / ニッチ / 自己複製 / がん / AF4 Less

単核貪食細胞系の生体内分化における局所的DNA脱メチル化とその生物学的意義の解明
- Principal Investigator
  
  田村智彦
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Yokohama City University
疾病よる転写因子IRF8の発現変化の分子メカニズムの解明Principal Investigator
- Principal Investigator
  
  奥田博史
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Yokohama City University
RNA-binding proteins control the oncogenic activity of MLL-AF4Principal Investigator
- Principal Investigator
  
  OKUDA Hiroshi
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 54010:Hematology and medical oncology-related
- Research Institution
  Yokohama City University
  National Cancer Center Japan
Mechanism of leukemogenesis through MLL-AF4 and its regulatory factorsPrincipal Investigator
- Principal Investigator
  
  Okuda Hiroshi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Hematology
- Research Institution
  National Cancer Center Japan
新規MLL-AEP転写活性化複合体を介した白血病化メカニズムPrincipal Investigator
- Principal Investigator
  
  奥田博史
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Mechanisms of niche-independent self-renewal by MLL fusion proteins
- Principal Investigator
  
  YOKOYAMA Akihiko
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  Hematology
- Research Institution
  Kyoto University
Mechanism of transcriptional activation and leukemogenesis by AF4Principal Investigator
- Principal Investigator
  
  OKUDA HIROSHI
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyoto University
The role of the AEP complex in MLL fusion-dependent leukemogenesis
- Principal Investigator
  
  YOKOYAMA Akihiko
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Hematology
- Research Institution
  Kyoto University

All 2024 2023 2022 2017 2014

All Journal Article Presentation

[Journal Article] RNA-Binding Proteins of KHDRBS and IGF2BP families control the Oncogenic Activity of MLL-AF42022
- Author(s)
  Okuda H, Miyamoto M, Takahashi S, Kawamura T Ichikawa J, Harada I, Tamura T and Yokoyama A.
- Journal Title
  
  Nature Communications
  
  Volume: 13 Issue: 1 Pages: 6688-6688
- DOI
  10.1038/s41467-022-34558-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22KK0119, KAKENHI-PROJECT-20K08722, KAKENHI-PROJECT-23K24368, KAKENHI-PROJECT-21H02954
[Journal Article] Myeloid Progenitor Transformation Assay2017
- Author(s)
  Okuda Hiroshi、Yokoyama Akihiko
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 7 Issue: 23
- DOI
  10.21769/bioprotoc.2626
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07379
[Journal Article] In vivo Leukemogenesis Model Using Retrovirus Transduction2017
- Author(s)
  Okuda Hiroshi、Yokoyama Akihiko
- Journal Title
  
  BIO-PROTOCOL
  
  Volume: 7 Issue: 23
- DOI
  10.21769/bioprotoc.2627
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H07379
[Journal Article] MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters2014
- Author(s)
  Okuda H, Kawaguchi M, Kanai A, Matsui H, Kawamura T, Inaba T, Kitabayashi I, Yokoyama A
- Journal Title
  
  Nucleic Acid Research
  
  Volume: 未定 Issue: 7 Pages: 1-16
- DOI
  10.1093/nar/gkt1394
- NAID
  120005439160
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-22118003, KAKENHI-PROJECT-23689050, KAKENHI-PROJECT-24591397, KAKENHI-PUBLICLY-25118511, KAKENHI-PROJECT-25670450, KAKENHI-PROJECT-25870373
[Presentation] Revised model of interferon regulatory factor 8 (IRF8)-dose dependent myeloid cell differentiation2024
- Author(s)
  Hiroshi Okuda, Juri Ichikawa, Takaya Yamasaki, Hiroaki Kume, Kenichi Asano, Tomohiko Tamura
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-23K06586
[Presentation] RNA結合タンパク質による MLL-AF4の発現制御メカニズム2023
- Author(s)
  奥田博史、宮本亮、高橋慧、市川珠理、原田生起、田村智彦、横山明彦
- Organizer
  第18回血液学若手研究者勉強会（麒麟塾）
- Data Source
  KAKENHI-PROJECT-20K08722
[Presentation] RNA結合タンパク質による MLL-AF4の翻訳阻害メカニズム2022
- Author(s)
  奥田博史、宮本亮、高橋慧、市川珠理、原田生起、田村智彦、横山明彦
- Organizer
  第26回造血器腫瘍研究会
- Data Source
  KAKENHI-PROJECT-20K08722

1. YOKOYAMA Akihiko (10506710)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. 田村智彦 (50285144)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. ラミロフスキージョーダン (10627269)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 西山晃 (80589664)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 川村猛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okuda Hiroshi 奥田 博史

OKUDA Hiroshi 奥田 博史

Research Projects

Research Products

Co-Researchers

単核貪食細胞系の生体内分化における局所的DNA脱メチル化とその生物学的意義の解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

疾病よる転写因子IRF8の発現変化の分子メカニズムの解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

RNA-binding proteins control the oncogenic activity of MLL-AF4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mechanism of leukemogenesis through MLL-AF4 and its regulatory factorsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

新規MLL-AEP転写活性化複合体を介した白血病化メカニズムPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanisms of niche-independent self-renewal by MLL fusion proteins

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Mechanism of transcriptional activation and leukemogenesis by AF4Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of the AEP complex in MLL fusion-dependent leukemogenesis

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] RNA-Binding Proteins of KHDRBS and IGF2BP families control the Oncogenic Activity of MLL-AF42022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Myeloid Progenitor Transformation Assay2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] In vivo Leukemogenesis Model Using Retrovirus Transduction2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] MLL fusion proteins link transcriptional coactivators to previously active CpG-rich promoters2014

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] Revised model of interferon regulatory factor 8 (IRF8)-dose dependent myeloid cell differentiation2024

Author(s)

Organizer

Data Source

[Presentation] RNA結合タンパク質による MLL-AF4の発現制御メカニズム2023

Author(s)

Okuda Hiroshi 奥田博史

OKUDA Hiroshi 奥田博史