Hayashi Yoshitaka 林義剛

Researcher Number	10631567
Other IDs
Affiliation (Current)	2025: 滋賀医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2017 – 2023: 滋賀医科大学, 医学部, 助教 2014 – 2016: 滋賀医科大学, 医学部, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related / Laboratory animal science / Neurochemistry/Neuropharmacology
Keywords	Principal Investigator オリゴデンドロサイト / エピジェネティクス / 気分障害 / 大うつ病 / カニクイザル / RNA-seq / RRBS / DNAメチル化 / オリゴデンドロサイト前駆細胞 / うつ病モデル … More / 非ヒト霊長類 / エピゲノム / モデル動物 / インターフェロンα / うつ病モデル動物 Less

自殺者死後脳の細胞種特異的エピジェネティクス異常とRNA発現変化の相互解析Principal Investigator
- Principal Investigator
  
  林義剛
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Shiga University of Medical Science
Analysis of the relationship between oligodendrocyte epigenetics and the pathogenesis of mood disorders.Principal Investigator
- Principal Investigator
  
  Hayashi Yoshitaka
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Shiga University of Medical Science
Cell type-specific epigenomic analysis of brain in a non-human primate model of depressionPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshitaka
- Project Period (FY)
  2017 – 2020
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Laboratory animal science
- Research Institution
  Shiga University of Medical Science
Establishment of interferon induced depression model monkey and analysis of brain cell abnormalityPrincipal Investigator
- Principal Investigator
  
  Hayashi Yoshitaka
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Neurochemistry/Neuropharmacology
- Research Institution
  Shiga University of Medical Science

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Fut9 Deficiency Causes Abnormal Neural Development in the Mouse Cerebral Cortex and Retina2022
- Author(s)
  Abdullah Asmaa、Hayashi Yoshitaka、Morimura Naoko、Kumar Akhilesh、Ikenaka Kazuhiro、Togayachi Akira、Narimatsu Hisashi、Hitoshi Seiji
- Journal Title
  
  Neurochemical Research
  
  Volume: 47 Issue: 9 Pages: 2793-2804
- DOI
  10.1007/s11064-022-03651-8
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07758, KAKENHI-PROJECT-22K06429
[Journal Article] 精神科ブレインバンク死後脳を用いたうつ病研究2022
- Author(s)
  林義剛、等誠司
- Journal Title
  
  月刊精神科
  
  Volume: 40 Pages: 441-447
- Data Source
  KAKENHI-PROJECT-20K07758
[Journal Article] Life-Long Neural Stem Cells Are Fate-Specified at an Early Developmental Stage2020
- Author(s)
  Tanaka Aoi、Ishida Shohei、Fuchigami Takahiro、Hayashi Yoshitaka、Kuroda Anri、Ikenaka Kazuhiro、Fukazawa Yugo、Hitoshi Seiji
- Journal Title
  
  Cerebral Cortex
  
  Volume: 30 Issue: 12 Pages: 6415-6425
- DOI
  10.1093/cercor/bhaa200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07758, KAKENHI-PUBLICLY-20H05058, KAKENHI-PROJECT-19H03323, KAKENHI-PROJECT-17K17815
[Journal Article] Adult neurogenesis and its role in brain injury and psychiatric diseases2018
- Author(s)
  Hayashi Yoshitaka、Jinnou Hideo、Sawamoto Kazunobu、Hitoshi Seiji
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 147 Issue: 5 Pages: 584-594
- DOI
  10.1111/jnc.14557
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K17815, KAKENHI-PROJECT-17K18007, KAKENHI-PUBLICLY-17H05512, KAKENHI-PUBLICLY-17H05750, KAKENHI-PROJECT-17H01392, KAKENHI-PROJECT-16K14578, KAKENHI-PROJECT-16H06280
[Journal Article] 特集大脳皮質-成り立ちから機能へグリア細胞の分化･発生の時期と関連因子2017
- Author(s)
  林義剛, 等誠司.
- Journal Title
  
  生体の科学
  
  Volume: 68 Issue: 1 Pages: 24-28
- DOI
  10.11477/mf.2425200568
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2017-02-15
- Data Source
  KAKENHI-PROJECT-26870282, KAKENHI-PROJECT-17K17815
[Journal Article] Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasiticity of the deveroping, mature, and diseased brain.2016
- Author(s)
  Yamaguchi M, Seki T, Imayoshi I, Tamamaki N, Hayashi Y, Tatebayashi Y, Hitoshi S.
- Journal Title
  
  Journal of Physiological Science
  
  Volume: 66(3) Issue: 3 Pages: 197-206
- DOI
  10.1007/s12576-015-0421-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26870282, KAKENHI-PUBLICLY-26115506, KAKENHI-PROJECT-15H04256, KAKENHI-PROJECT-25430041, KAKENHI-PUBLICLY-15H01443, KAKENHI-PROJECT-16H04671, KAKENHI-PROJECT-16K07033, KAKENHI-PROJECT-16K14578
[Journal Article] Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body2016
- Author(s)
  Seita Y, Tsukiyama T, Iwatani C, Tsuchiya H, Matsushita J, Azami T, Okahara J, Nakamura S, Hayashi Y, Hitoshi S, Itoh Y, Imamura T, Nishimura M, Tooyama I, Miyoshi H, Saitou M, Ogasawara K, Sasaki E, Ema M
- Journal Title
  
  Scientific Reports
  
  Volume: 2 Issue: 1 Pages: 24868-24868
- DOI
  10.1038/srep24868
- NAID
  130007023590
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26640053, KAKENHI-PROJECT-15K21080, KAKENHI-PROJECT-16H04671, KAKENHI-PROJECT-26430070, KAKENHI-PROJECT-26870282, KAKENHI-PROJECT-16K14578
[Presentation] DNA methylation states of neurons and oligodendrocyte lineage cells in human postmortem brain.2023
- Author(s)
  Yoshitaka Hayashi，Kazuhiko Nakabayashi，Yasuhiro Go，Masahito Hitosugi，Seiji Hitoshi.
- Organizer
  第64回日本神経病理学会総会学術研究会・第66回日本神経化学会 2023
- Data Source
  KAKENHI-PROJECT-20K07758
[Presentation] Glial cells missing 1 induce glial cells and angiogenesis in the injured region of brain.2023
- Author(s)
  Yoshitaka Hayashi, Yasuhiro Go, Kazuhiko Nakabayashi, Asmaa Abdullah, Mohd Azrah, Mohd Zakiyyah, Seiji Hitoshi
- Organizer
  第100回日本生理学会
- Data Source
  KAKENHI-PROJECT-20K07758
[Presentation] Glial cells missing 1 induce glial cells and angiogenesis in the core region of brain injury.2022
- Author(s)
  Yoshitaka Hayashi, Yasuhiro Go, Kazuhiko Nakabayashi, Asmaa Abdullah, Mohd Zakiyyah, Seiji Hitoshi
- Organizer
  Neuro2022
- Data Source
  KAKENHI-PROJECT-20K07758
[Presentation] ヒト死後脳における神経細胞とオリゴデンドロサイト系譜細胞の DNAメチル化状態の解析2021
- Author(s)
  林義剛, Kazuhiko Nakabayashi, Yasuhiro Go, Junya Kamiyasuhira, Asmaa Abdullah, Mohd Zakiyyah, Seiji Hitoshi
- Organizer
  第64回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K07758
[Presentation] Glial cells missing 1は損傷脳においてグリア細胞分化と血管新生を促進する.2020
- Author(s)
  林義剛, 福家聡, 郷康広, 中林一彦, Adbullah Asmaa, Mohd Zakiyyah, 守村直子, Daun Kenny, 小山なつ, 等誠司.
- Organizer
  第63回日本神経化学会大会. 2020
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Glial cells missing 1は損傷脳においてグリア細胞分化と血管新生を促進する.2020
- Author(s)
  林義剛, 福家聡, 郷康広, 中林一彦, Adbullah Asmaa, Mohd Zakiyyah, 守村直子, Daun Kenny, 小山なつ, 等誠司.
- Organizer
  第63回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-20K07758
[Presentation] Glial cells missing 1 promote cell differentiation and angiogenesis by growth factor expression.2019
- Author(s)
  Yoshitaka Hayashi, Satoshi Fuke, Yasuhiro Go, Asmaa Abdullah, Takahiro Fuchigami, Naoko Morimura, Natsu Koyama, Seiji Hitoshi
- Organizer
  2019 ASN-ISN
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Gcm1 regulates glial cell differentiation and angiogenesis in the mammalian brain2019
- Author(s)
  Yoshitaka Hayashi
- Organizer
  グリア研究会
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Glial cells missing 1 は成長因子分泌を促進し、細胞の分化・増殖および血管新生を誘導する2019
- Author(s)
  Yoshitaka Hayashi, Satoshi Fuke, Yasuhiro Go, Kazuhiko Nakabayashi, Takahiro Fuchigami, Naoko Morimura, Natsu Koyama, Seiji Hitoshi
- Organizer
  Neuro 2019
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Glial cells missing 1 promote cell differentiation and angiogenesis in the mammalian brain2019
- Author(s)
  Yoshitaka Hayashi, Satoshi Fuke, Takahiro Fuchigami, Naoko Morimura, Natsu Koyama, Seiji Hitoshi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Glial cells missing 1は損傷脳において細胞分化・増殖と血管新生を促進する2018
- Author(s)
  林義剛, 福家聡, 郷康広, 中林一彦, アスマビンティアブドゥラー, 渕上孝裕, 守村直子, 小山なつ, 等誠司
- Organizer
  第15回成体脳ニューロン新生懇談会
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] The oligodendroglial abnormalities in the postmortem brain from human patients and monkey depression model2018
- Author(s)
  Yoshitaka Hayashi, Yasuhiro Go, Natsu Koyama, Seiji Hitoshi
- Organizer
  Towards Understanding “INDIVIDUALITY”
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] Glial cells missing 1 promote cell differentiation, proliferation and angiogenesis in the mammalian brain2018
- Author(s)
  Yoshitaka Hayashi
- Organizer
  15th Meeting of Asian-Pacific Society for Neurochemistry
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] The oligodendroglial abnormalities in the postmortem brain from human patients and monkey depression model.2017
- Author(s)
  Yoshitaka Hayashi, Satoshi Fuke, Kazuhiko Nakabayashi, Takahiro Fuchigami, Naoko Morimura, Yoshitaka Tatebayashi, Seiji Hitoshi
- Organizer
  ISN-ESN 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] The oligodendroglial abnormalities in the postmortem brain from human patients and monkey depression model2017
- Author(s)
  Hayashi Y, Fuke S, Nakabayashi K, Fuchigami T, Morimura N, Tatebayashi Y, Hitoshi S.
- Organizer
  2017 ISN-ESN
- Place of Presentation
  Paris, France
- Year and Date
  2017-08-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] Functional analysis of Glial cell missing 1 in the mammalian brain.2017
- Author(s)
  Yoshitaka Hayashi, Satoshi Fuke, Takahiro Fuchigami, Naoko Morimura, Natsu Koyama, Seiji Hitoshi
- Organizer
  第60回日本神経化学会大会
- Data Source
  KAKENHI-PROJECT-17K17815
[Presentation] インターフェロンα誘発性カニクイザルうつ病モデルの解析2016
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  第38回日本生物学的精神医学会・第59回日本神経化学会大会合同年会
- Place of Presentation
  福岡
- Year and Date
  2016-09-08
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] 胎生期神経前駆細胞に対するGlial cell missingの機能解析2015
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  第38回日本分子生物学会、第88回日本生化学会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] The oligodendoroglial abnormalities in mood disorders: a study of human and monkey post mortem brain2015
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  25th ISN-APSN Joint Biennial Meeting
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-23
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] 前頭葉オリゴデンドロサイト系譜細胞と精神機能2015
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  第92回日本生理学会大会合同大会
- Place of Presentation
  兵庫
- Year and Date
  2015-03-23
- Invited
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] Epigenetic mechanisms underlying the generation and differentiation of neural stem cells.2014
- Author(s)
  等誠司、林義剛、渕上孝裕、福家聡、石野雄吾、池中一裕
- Organizer
  12th International society for stem cell research
- Place of Presentation
  Vancouver, Canada
- Year and Date
  2014-06-19
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] 霊長類研究で探る大脳皮質の細胞新生と気分の関係2014
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  第57回日本神経化学会大会
- Place of Presentation
  奈良
- Year and Date
  2014-10-01
- Invited
- Data Source
  KAKENHI-PROJECT-26870282
[Presentation] The oligodendroglial abnormalities in mood disorders: a study of human and monkey post mortem brain
- Author(s)
  林義剛、福家聡、渕上孝裕、小山なつ、楯林義孝、等誠司
- Organizer
  25th ISN-APSN Joint Biennial Meeting
- Place of Presentation
  Cairns, Australia
- Year and Date
  2015-08-23 – 2015-08-27
- Data Source
  KAKENHI-PROJECT-26870282

1. TSUCHIYA Hideaki

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 伊藤靖

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 依馬正次

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 小笠原一誠

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 佐々木えりか

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hayashi Yoshitaka 林 義剛

Research Projects

Research Products

Co-Researchers

自殺者死後脳の細胞種特異的エピジェネティクス異常とRNA発現変化の相互解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of the relationship between oligodendrocyte epigenetics and the pathogenesis of mood disorders.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Cell type-specific epigenomic analysis of brain in a non-human primate model of depressionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Establishment of interferon induced depression model monkey and analysis of brain cell abnormalityPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Fut9 Deficiency Causes Abnormal Neural Development in the Mouse Cerebral Cortex and Retina2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 精神科ブレインバンク 死後脳を用いたうつ病研究2022

Author(s)

Journal Title

Data Source

[Journal Article] Life-Long Neural Stem Cells Are Fate-Specified at an Early Developmental Stage2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adult neurogenesis and its role in brain injury and psychiatric diseases2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 特集 大脳皮質-成り立ちから機能へ グリア細胞の分化･発生の時期と関連因子2017

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Journal Article] Neural stem cells and neuro/gliogenesis in the central nervous system: understanding the structural and functional plasiticity of the deveroping, mature, and diseased brain.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Generation of transgenic cynomolgus monkeys that express green fluorescent protein throughout the whole body2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] DNA methylation states of neurons and oligodendrocyte lineage cells in human postmortem brain.2023

Author(s)

Organizer

Data Source

[Presentation] Glial cells missing 1 induce glial cells and angiogenesis in the injured region of brain.2023

Author(s)

Organizer

Data Source

[Presentation] Glial cells missing 1 induce glial cells and angiogenesis in the core region of brain injury.2022

Author(s)

Organizer

Data Source

[Presentation] ヒト死後脳における神経細胞とオリゴデンドロサイト系譜細胞の DNAメチル化 状態の解析2021

Author(s)

Organizer

Hayashi Yoshitaka 林義剛

[Journal Article] 精神科ブレインバンク死後脳を用いたうつ病研究2022

[Journal Article] 特集大脳皮質-成り立ちから機能へグリア細胞の分化･発生の時期と関連因子2017

[Presentation] ヒト死後脳における神経細胞とオリゴデンドロサイト系譜細胞の DNAメチル化状態の解析2021

[Presentation] Glial cells missing 1 は成長因子分泌を促進し、細胞の分化・増殖および血管新生を誘導する2019

[Presentation] Glial cells missing 1は損傷脳において細胞分化・増殖と血管新生を促進する2018