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Nakahara Naoya  中原 直哉

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NAKAHARA Naoya  中原 直哉

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Researcher Number 10632193
Other IDs
Affiliation (Current) 2023: 東京慈恵会医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2019 – 2022: 東京慈恵会医科大学, 医学部, 助教
2012: 東京慈恵会医科大学, 医学部, 助教
Review Section/Research Field
Principal Investigator
Basic Section 52040:Radiological sciences-related / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 59010:Rehabilitation science-related / Mechanobiology / Basic Section 56060:Ophthalmology-related
Keywords
Principal Investigator
骨格筋 / DSC / 水 / MR信号 / 筋タンパク / X線回折法 / in vivo
Except Principal Investigator
骨格筋 / X線回折 / 横紋筋 … More / エックス線回折 / 収縮 / 筋節 / スキンドファイバー / 心筋 / ゲルゾリン / ミオシン / サルコメア / アクチン / Spring8 / ブタンジオンモノオキシム / 伸張性収縮 / 筋肥大 / 筋原性前駆細胞 / 斜視 / 術後の戻り / DNAマイクロアレイ / 筋節長 / 外眼筋 / 筋損傷 / 胎児型ミオシン / サテライト細胞 / 筋線維 Less
  • Research Projects

    (6 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (13 People)
  •  筋萎縮過程の解明を目指した構造・機能同時測定~in vivo骨格筋2次元X線回折Principal Investigator

    • Principal Investigator
      中原 直哉
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Jikei University School of Medicine
  •  血流と代謝状態を維持した骨格筋のX線回折法による伸張性収縮後の筋節内微細構造評価

    • Principal Investigator
      平野 和宏
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Jikei University School of Medicine
  •  筋原性前駆細胞に対する伸展誘導信号の抑制による「戻り」のない新規斜視治療法の開発

    • Principal Investigator
      飯田 貴絵
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 56060:Ophthalmology-related
    • Research Institution
      Jikei University School of Medicine
  •  新生筋線維の機能獲得過程:サテライト細胞が胎児型筋線維を経て成熟筋線維になるまで

    • Principal Investigator
      山口 眞紀
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59010:Rehabilitation science-related
    • Research Institution
      Jikei University School of Medicine
  •  Evaluation of interaction enthalpy between water and myoproteins in skeletal muscle for theoretical interpretation of MR signalsPrincipal Investigator

    • Principal Investigator
      Nakahara Naoya
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52040:Radiological sciences-related
    • Research Institution
      Jikei University School of Medicine
  •  Stretch of muscle sarcomere induces protrusion of myosinheads toward actin so as to facilitate formation of contractile cross-bridges.

    • Principal Investigator
      TAKEMORI Shigeru
    • Project Period (FY)
      2010 – 2012
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Mechanobiology
    • Research Institution
      Jikei University School of Medicine

All 2022 2021 2020 2019 2012 2011

All Journal Article Presentation

  • [Journal Article] Gene Transfer of Skeletal Muscle-Type Myosin Light Chain Kinase via Adeno-Associated Virus 6 Improves Muscle Functions in an Amyotrophic Lateral Sclerosis Mouse Model2022

    • Author(s)
      Oya Ryohei、Tsukamoto Osamu、Hitsumoto Tatsuro、Nakahara Naoya、Okamoto Chisato、Matsuoka Ken、Kato Hisakazu、Inohara Hidenori、Takashima Seiji
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Pages: 1747-1747

    • DOI

      10.3390/ijms23031747

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17180, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20K07338
  • [Journal Article] X-ray Diffraction Analysis to Explore Molecular Traces of Eccentric Contraction on Rat Skeletal Muscle Parallelly Evaluated with Signal Protein Phosphorylation Levels2021

    • Author(s)
      Hirano Kazuhiro、Yamauchi Hideki、Nakahara Naoya、Kinoshita Kazuo、Yamaguchi Maki、Takemori Shigeru
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 22 Pages: 12644-12644

    • DOI

      10.3390/ijms222312644

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Journal Article] Crossbridge Recruitment Capacity of Wild-Type and Hypertrophic Cardiomyopathy-Related Mutant Troponin-T Evaluated by X-ray Diffraction and Mechanical Study of Cardiac Skinned Fibers2020

    • Author(s)
      Yamaguchi Maki、Kimura Masako、Ohno Tetsuo、Nakahara Naoya、Akiyama Nobutake、Takemori Shigeru、Yagi Naoto
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Pages: 3520-3520

    • DOI

      10.3390/ijms21103520

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation] In vivo skeletal muscle x-ray diffraction study on the cause of reduced contractility after blood flow interruption2022

    • Author(s)
      中原直哉、山内秀樹、山口眞紀、林友則、平野和宏、竹森重
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation] X線回折法による血流を保った骨格筋の除神経後の変化2021

    • Author(s)
      中原直哉、山内秀樹、山口眞紀、平野和宏、竹森重
    • Organizer
      2020年度量子ビームサイエンスフェスタ
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation] Strategy of extraocular muscle to achieve super-fast shortening velocity: an x-ray diffraction study.2021

    • Author(s)
      Maki Yamaguchi, Toru Kurihara, Naoya Nakahara, Hideki Yamauchi, Kazuhiro Hirano, Tetsuo Ohno, Toshiko Yamazawa, Mai Yamaguchi, Shigeru Takemori.
    • Organizer
      第99回日本生理学会大会
    • Data Source
      KAKENHI-PROJECT-21K11249
  • [Presentation] Development of x-ray diffraction methods for in vivo skeletal muscle with maintained blood supply2021

    • Author(s)
      中原直哉、山内秀樹、山口眞紀、平野和宏、竹森重
    • Organizer
      第126回日本解剖学会総会・全国学術集会、第98回日本生理学会大会 合同大会
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation] 眼位の安定を左右する安静時外眼筋群の力学作用~斜視手術後を含む検討2021

    • Author(s)
      飯田貴絵、山口眞紀、中原直哉、山澤徳志子,竹森重,久保寛之,仲泊聡,中野匡
    • Organizer
      第125回日本眼科学会総会
    • Data Source
      KAKENHI-PROJECT-21K09755
  • [Presentation] Actin filaments render considerable heat capacity to skeletal muscle sa陀omere2020

    • Author(s)
      中原直哉
    • Organizer
      日本生理学会
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation] 熱測定で評価した骨格筋内の水と筋タンパクの相互作用2019

    • Author(s)
      中原直哉、大野哲生、木村雅子、木村澄子、竹森重
    • Organizer
      成医会
    • Data Source
      KAKENHI-PROJECT-19K17180
  • [Presentation]2012

    • Author(s)
      Takemori S, Kimura M, Yamaguchi M, Ohno T, Nakahara N, Yokomizo S
    • Organizer
      日本生物物理学会
    • Place of Presentation
      名古屋
    • Year and Date
      2012-09-23
    • Data Source
      KAKENHI-PROJECT-22616008
  • [Presentation] 細いフィラメント除去筋線維内でのミオシン頭部の振る舞い2011

    • Author(s)
      山口眞紀,竹森 重,木村雅子,大野哲生,中原直哉,八木直人
    • Organizer
      日本生理学会大会・日本解剖学会総会合同大会
    • Place of Presentation
      紙上開催
    • Data Source
      KAKENHI-PROJECT-22616008
  • 1.  YAMAGUCHI Maki (30271315)
    # of Collaborated Projects: 5 results
    # of Collaborated Products: 4 results
  • 2.  TAKEMORI Shigeru (20179675)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 3 results
  • 3.  山内 秀樹 (60220224)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 1 results
  • 4.  平野 和宏 (40874821)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 0 results
  • 5.  山澤 徳志子 (00282616)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 0 results
  • 6.  KIMURA Masako (30328314)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 7.  OHNO Tetsuo (30233224)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 8.  飯田 貴絵 (00897168)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 9.  秋山 暢丈 (00338865)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 10.  TAKASHIMA Seiji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 11.  KATO Hisakazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 12.  松岡 研
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 13.  高橋 徳志子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results

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