Watanabe Masashi 渡部昌

… Alternative Names

WATANABE masashi 渡部昌

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Researcher Number	10632424
Other IDs
Affiliation (Current)	2025: 北海道大学, 医学研究院, 講師
Affiliation (based on the past Project Information) *help	2018 – 2024: 北海道大学, 医学研究院, 講師 2017: 北海道大学, 医学研究院, 助教 2016: 北海道大学, 医学研究科, 助教 2012 – 2015: 北海道大学, 医学(系)研究科(研究院), 助教
Review Section/Research Field	Principal Investigator General medical chemistry / Basic Section 49010:Pathological biochemistry-related / Medium-sized Section 44:Biology at cellular to organismal levels, and related fields / Complex systems / Environmental physiology(including physical medicine and nutritional physiology) Except Principal Investigator Biomedical structure and function and related fields / General medical chemistry
Keywords	Principal Investigator ユビキチン / ユビキチンリガーゼ / プロテオミクス / がん / PPARガンマー / 医化学 / プローブ / ポリユビキチン鎖 / TRIMタンパク質 / 自然免疫 … More / クロマチン / ゲノム / Ufm1 / UFM1 / ユビキチン様修飾分子 … More Except Principal Investigator シグナル伝達 / ユビキチン / 生体分子 / プロテオーム / 蛋白質 / Parkin / TUBE / TRIM型E3 / 転写 / タンパク質修飾 / タンパク質分解 Less

がんドライバーユビキチンリガーゼの網羅的基質探索による創薬基盤の確立Principal Investigator
- Principal Investigator
  
  渡部昌
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Hokkaido University
Functional analysis of cancer driver ubiquitin ligase using a newly developed substrate identification method.Principal Investigator
- Principal Investigator
  
  Watanabe Masashi
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49010:Pathological biochemistry-related
- Research Institution
  Hokkaido University
Comprehensive identification of polyubiquitinated substrates for elucidation of the "ubiquitin code"Principal Investigator
- Principal Investigator
  
  watanabe masashi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 44:Biology at cellular to organismal levels, and related fields
- Research Institution
  Hokkaido University
自然免疫シグナルにおけるユビキチン化基質の網羅的同定と解析Principal Investigator
- Principal Investigator
  
  渡部昌
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Establishment of method for identification of ubiquitinated protein
- Principal Investigator
  
  Hatakeyama Shigetsugu
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Research Field
  
  Biomedical structure and function and related fields
- Research Institution
  Hokkaido University
Defense mechanism against lifestyle diseases by ubiquitin-like modifier UFM1Principal Investigator
- Principal Investigator
  
  watanabe masashi
- Project Period (FY)
  2016 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  Environmental physiology(including physical medicine and nutritional physiology)
- Research Institution
  Hokkaido University
Devolopment of a novel method to identify E3 ligase substratesPrincipal Investigator
- Principal Investigator
  
  WATANABE MASASHI
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
Regulation of signal transduction by TRIM family proteins
- Principal Investigator
  
  Hatakeyama Shigetsugu
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARgammaPrincipal Investigator
- Principal Investigator
  
  WATANABE masashi
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University
ユビキチン化による脂質代謝制御転写因子PPARガンマーの活性化制御機構の解明Principal Investigator
- Principal Investigator
  
  渡部昌
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General medical chemistry
- Research Institution
  Hokkaido University

All 2023 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation Book

[Book] Advances in Medicine and Biology. Volume 1202017
- Author(s)
  Masashi Watanabe and Shigetsugu Hatakeyama
- Total Pages
  23
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-15K15058
[Book] Advances in Medicine and Biology. Volume 1202017
- Author(s)
  Masashi Watanabe and Shigetsugu Hatakeyama
- Total Pages
  23
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-16H06221
[Book] Ubiquitin-conjugating enzymes (E2s): Adnances in Medicine and Biology Vol 1202017
- Author(s)
  Watanabe, M. and Hatakeyama, S.
- Total Pages
  23
- Publisher
  Nova Science Publishers
- Data Source
  KAKENHI-PROJECT-15H04690
[Journal Article] FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA2023
- Author(s)
  Kasuga Yusuke、Ouda Ryota、Watanabe Masashi、Sun Xin、Kimura Miki、Hatakeyama Shigetsugu、Kobayashi Koichi S.
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 24
- DOI
  10.1073/pnas.2218955120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19415, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-21H02690
[Journal Article] TRIM27 expression is associated with poor prognosis in sinonasal mucosal melanoma2023
- Author(s)
  Kimura S、Suzuki M、Nakamaru Y、Kano S、Watanabe M、Honma A、Nakazono A、Tsushima N、Hatakeyama S、Homma A
- Journal Title
  
  Rhinology Journal
  
  Volume: - Issue: 0 Pages: 0-0
- DOI
  10.4193/rhin22.405
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H02690, KAKENHI-PROJECT-18K16871, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-22K16923, KAKENHI-PROJECT-18KK0444, KAKENHI-PROJECT-22K19415, KAKENHI-PROJECT-21H02674
[Journal Article] TRIM22 negatively regulates MHC-II expression2022
- Author(s)
  Inoue Ayano、Watanabe Masashi、Kondo Takeshi、Hirano Satoshi、Hatakeyama Shigetsugu
- Journal Title
  
  Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  
  Volume: 1869 Issue: 10 Pages: 119318-119318
- DOI
  10.1016/j.bbamcr.2022.119318
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19415, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-21H02690, KAKENHI-PUBLICLY-21H00266
[Journal Article] Role of intracellular zinc in molecular and cellular function in allergic inflammatory diseases2021
- Author(s)
  Suzuki Masanobu、Suzuki Takayoshi、Watanabe Masashi、Hatakeyama Shigetsugu、Kimura Shogo、Nakazono Akira、Honma Aya、Nakamaru Yuji、Vreugde Sarah、Homma Akihiro
- Journal Title
  
  Allergol. Int.
  
  Volume: 70 Issue: 2 Pages: 190-200
- DOI
  10.1016/j.alit.2020.09.007
- NAID
  130008024307
- ISSN
  1323-8930, 1440-1592
- Language
  English
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-19H05280, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-18KK0444
[Journal Article] Loss of FAM83H promotes cell migration and invasion in cutaneous squamous cell carcinoma via impaired keratin distribution2021
- Author(s)
  Tokuchi Keiko、Kitamura Shinya、Maeda Takuya、Watanabe Masashi、Hatakeyama Shigetsugu、Kano Satoshi、Tanaka Shinya、Ujiie Hideyuki、Yanagi Teruki
- Journal Title
  
  Journal of Dermatological Science
  
  Volume: 104 Issue: 2 Pages: 112-121
- DOI
  10.1016/j.jdermsci.2021.09.007
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-21H02690, KAKENHI-PROJECT-21K16201
[Journal Article] Fluticasone Propionate Suppresses Poly(I:C)-Induced ACE2 in Primary Human Nasal Epithelial Cells2021
- Author(s)
  Nakazono Akira、Nakamaru Yuji、Ramezanpour Mahnaz、Kondo Takeshi、Watanabe Masashi、Hatakeyama Shigetsugu、Kimura Shogo、Honma Aya、Wormald P. J.、Vreugde Sarah、Suzuki Masanobu、Homma Akihiro
- Journal Title
  
  Frontiers in Cellular and Infection Microbiology
  
  Volume: 11 Pages: 655666-655666
- DOI
  10.3389/fcimb.2021.655666
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-21H00266, KAKENHI-PROJECT-21H02674, KAKENHI-PROJECT-21H02690, KAKENHI-PROJECT-18K16871, KAKENHI-PROJECT-19K18718, KAKENHI-PROJECT-18KK0444
[Journal Article] A substrate-trapping strategy to find E3 ubiquitin ligase substrates identifies Parkin and TRIM28 targets2020
- Author(s)
  Watanabe Masashi、Saeki Yasushi、Takahashi Hidehisa、Ohtake Fumiaki、Yoshida Yukiko、Kasuga Yusuke、Kondo Takeshi、Yaguchi Hiroaki、Suzuki Masanobu、Ishida Hiroki、Tanaka Keiji、Hatakeyama Shigetsugu
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 592-592
- DOI
  10.1038/s42003-020-01328-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K22408, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-19H00997, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-19K22401, KAKENHI-PLANNED-18H05498, KAKENHI-PROJECT-17H03986, KAKENHI-ORGANIZER-18H05497
[Journal Article] The role of Mediator and Little Elongation Complex in transcription termination2020
- Author(s)
  Takahashi H, Ranjan A, Chen S, Suzuki H, Shibata M, Hirose T, Hirose H, Sasaki K, Abe R, Chen K, He Y, Zhang Y, Takigawa I, Tsukiyama T, Watanabe M, Fujii S, Iida M, Yamamoto J, Yamaguchi Y, Suzuki Y, Matsumoto M, Nakayama KI, Washburn P, Saraf A, Florens L, Sato S, Tomomori-Sato C, Conaway RC, Conaway JW, Hatakeyama S
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 1-20
- DOI
  10.1038/s41467-020-14849-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07633, KAKENHI-PROJECT-19K22408, KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-19H04969, KAKENHI-PUBLICLY-19H05243, KAKENHI-PROJECT-17H06112, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-16K07105, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-19H05280, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-20H03182, KAKENHI-PROJECT-19K22401
[Journal Article] Mutations in bassoon in individuals with familial and sporadic progressive supranuclear palsy-like syndrome2018
- Author(s)
  Yabe I, Yaguchi H, Kato Y, Miki Y, Takahashi H, Tanikawa S, Shirai S, Takahashi I, Kimura M, Hama Y, Matsushima M, Fujioka S, Kano T, Watanabe M, Nakagawa S, Kunieda Y, Ikeda Y, Hasegawa M, Nishihara H, Ohtsuka T, Tanaka S, Tsuboi Y, Hatakeyama S, Wakabayashi K, Sasaki H
- Journal Title
  
  Sci Rep
  
  Volume: 8 Issue: 1 Pages: 819-819
- DOI
  10.1038/s41598-018-19198-0
- NAID
  120006377499
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K09663, KAKENHI-PROJECT-16K09665, KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05560, KAKENHI-PUBLICLY-17H05741, KAKENHI-PUBLICLY-17H05989, KAKENHI-PLANNED-26117005, KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-15H04272, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-17K19578
[Journal Article] Brain-Derived Neurotrophic Factor Improves Limited Exercise Capacity in Mice With Heart Failure2018
- Author(s)
  Matsumoto Junichi、et al. Hatakeyama Shigetsugu、Matsumoto Masaki、Nakayama Keiichi I.、Otsuka Yutaro、Sabe Hisataka、Tsutsui Hiroyuki、Anzai Toshihisa
- Journal Title
  
  Circulation
  
  Volume: 138 Issue: 18 Pages: 2064-2066
- DOI
  10.1161/circulationaha.118.035212
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18H05215, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-18H03187, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17H04758, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] Anti-Sez6l2 antibody, detected in a patient with immune-mediated cerebellar ataxia, inhibits complex formation of GluR1 and Sez6l22018
- Author(s)
  Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Watanabe, M. and Hatakeyama, S.
- Journal Title
  
  J. Neurol.
  
  Volume: 265 Issue: 4 Pages: 962-965
- DOI
  10.1007/s00415-018-8785-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-16H06221, KAKENHI-PUBLICLY-17H05784, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-17K19578
[Journal Article] Loss of TRIM29 Alters Keratin Distribution to Promote Cell Invasion in Squamous Cell Carcinoma.2018
- Author(s)
  Yanagi T, Watanabe M, Hata H, Kitamura S, Imafuku K, Yanagi H, Homma A, Wang L, Takahashi H, Shimizu H, Hatakeyama S.
- Journal Title
  
  Cancer Res
  
  Volume: 78 Issue: 24 Pages: 6795-6806
- DOI
  10.1158/0008-5472.can-18-1495
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08259, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-18H02378, KAKENHI-PROJECT-18H02607, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578
[Journal Article] Fine-tuning of thymocyte development by ubiquitination-mediated stability control of the ESCRT protein CHMP52017
- Author(s)
  Watanabe, M. and Hatakeyama, S.
- Journal Title
  
  Cell. Moll. Immnol.
  
  Volume: 14 Issue: 12 Pages: 957-959
- DOI
  10.1038/cmi.2017.91
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19506, KAKENHI-PUBLICLY-17H05784, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-16H06221
[Journal Article] TRIM proteins and diseases.2017
- Author(s)
  Watanabe, M. and Hatakeyama, S
- Journal Title
  
  J. Biochem.
  
  Volume: 161 Pages: 135-144
- DOI
  10.1093/jb/mvw087
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-15K15058
[Journal Article] Sez6l2 regulates phosphorylation of ADD and neuritogenesis2017
- Author(s)
  Yaguchi, H., Yabe, I., Takahashi, H., Watanabe, M., Nomura, T., Kano, T., Matsumoto, M., Nakayama, K.I., Watanabe, M. and Hatakeyama, S.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 494 Issue: 1-2 Pages: 234-241
- DOI
  10.1016/j.bbrc.2017.10.047
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K19506, KAKENHI-PROJECT-17K19578, KAKENHI-PUBLICLY-17H05989, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221
[Journal Article] Regulation of intestinal homeostasis by theulcerative colitis-associated gene RNF186.2017
- Author(s)
  Fujimoto K, Kinoshita M, Tanaka H, Okuzaki D, Shimada Y, Kayama H, Okumura R, Furuta Y, Narazaki M, Tamura A, Hatakeyama S, Ikawa M, Tsuchiya K, Watanabe M, Kumanogoh A, Tsukita S, Takeda K
- Journal Title
  
  Mucosal Immunol.
  
  Volume: 10 Issue: 2 Pages: 446-459
- DOI
  10.1038/mi.2016.58
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26221307, KAKENHI-PROJECT-15H02511, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04808, KAKENHI-PROJECT-15K15152, KAKENHI-ORGANIZER-25112001, KAKENHI-PLANNED-24113002
[Journal Article] p53 represses the transcription of snRNA genes by preventing the formation of little elongation complex2016
- Author(s)
  Anwar, D., Takahashia, H., Watanabe, M., Suzuki, M., Fukuda, S., Hatakeyama, S.
- Journal Title
  
  Biochim. Biophys. Acta-Gene Regul. Mech.
  
  Volume: 1859 Issue: 8 Pages: 975-982
- DOI
  10.1016/j.bbagrm.2016.06.001
- NAID
  120006328999
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-15K15058
[Journal Article] The novel heart-specific RING finger protein 207 is involved in energy metabolism in cardiomyocytes.2016
- Author(s)
  Mizushima, W., Takahashi , H., Watanabe, M., Kinugawa, S., Matsushima, S., Takada, S., Yokota, T., Furihata, T., Matsumoto, J., Tsuda, M., Chiba, I., Nagashima, S., Yanagi, S., Matsumoto, M., Nakayama, K.I., Tsutsui, H. and Hatakeyama, S.
- Journal Title
  
  J. Mol. Cell. Cardiol.
  
  Volume: 100 Pages: 43-53
- DOI
  10.1016/j.yjmcc.2016.09.013
- NAID
  120006360069
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-15H04815, KAKENHI-PROJECT-16H04730, KAKENHI-PROJECT-16H06221, KAKENHI-PROJECT-26350879, KAKENHI-PROJECT-15K15058, KAKENHI-PROJECT-26750331
[Journal Article] TRIM39 negatively regulates the NFκB-mediated signaling pathway through stabilization of Cactin2016
- Author(s)
  Suzuki M, Watanabe M, Nakamaru Y, Takagi D, Takahashi H, Fukuda S, Hatakeyama S.
- Journal Title
  
  Cell Mol Life Sci.
  
  Volume: ７３ Issue: 5 Pages: 1085-1101
- DOI
  10.1007/s00018-015-2040-x
- NAID
  120005981342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26462575, KAKENHI-PROJECT-15K15058, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130
[Journal Article] The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipocyte activator PPAR gamma.2015
- Author(s)
  Watanabe, M., Takahashi, H., Saeki, Y., Ozaki, T., Itoh, S., Suzuki, M., Mizushima, W., Tanaka, K. and Hatakeyama, S.
- Journal Title
  
  eLIFE
  
  Volume: 4
- DOI
  10.7554/elife.05615
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-15K15058, KAKENHI-PLANNED-24112006, KAKENHI-PLANNED-24112008, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04690, KAKENHI-PROJECT-15H04701, KAKENHI-PROJECT-26670130, KAKENHI-PROJECT-26000014
[Journal Article] MED26 regulates the transcription of snRNA genes through the recruitment of little elongation complex2015
- Author(s)
  Takahashi, H., Takigawa, I., Watanabe, M., Anwar, D., Shibata, M., Tomomori-Sato, C., Sato, S., Ranjan, A., Seidel, C.W., Tsukiyama, T., Mizushima, W., Hayashi, M., Ohkawa, Y., Conaway, J.W., Conaway, R.C. and Hatakeyama, S
- Journal Title
  
  Nature Commun.
  
  Volume: 5 Issue: 1 Pages: 5941-5941
- DOI
  10.1038/ncomms6941
- NAID
  120005621881
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-24689016, KAKENHI-PLANNED-25116010, KAKENHI-PUBLICLY-25118501, KAKENHI-PROJECT-25280079, KAKENHI-PROJECT-25430102, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-26290064, KAKENHI-PROJECT-26670130, KAKENHI-PLANNED-24118002, KAKENHI-PROJECT-15H04701
[Journal Article] Pathology of frontotemporal dementia with limb girdle muscular dystrophy caused by DNAJB6 mutation2014
- Author(s)
  Yabe, I., Tanino, M., Yaguchi, H., Takiyama, A., Cai, H., Kanno, H., Takahashi, I., Hayashi, Y., Watanabe, M., Takahashi, H., Hatakeyama, S., Tanaka, S. and Sasaki, H.
- Journal Title
  
  Clin. Neurol. Neurosur.
  
  Volume: 127 Pages: 10-12
- DOI
  10.1016/j.clineuro.2014.09.013
- NAID
  120005540291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25860201, KAKENHI-PROJECT-26310209
[Journal Article] TRIM29 as a novel prostate basal cell marker for diagnosis of prostate cancer2014
- Author(s)
  Kanno, Y., Watanabe, M., Kimura, T., Nonomura, K., Tanaka, S. and Hatakeyama, S
- Journal Title
  
  Acta Histochem
  
  Volume: 116 Issue: 5 Pages: 708-712
- DOI
  10.1016/j.acthis.2013.12.009
- NAID
  120005472205
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PLANNED-24112006, KAKENHI-PROJECT-24390065, KAKENHI-PROJECT-25460471, KAKENHI-PROJECT-25670134, KAKENHI-PROJECT-25860201
[Journal Article] TRIM型ユビキチンリガーゼと癌2012
- Author(s)
  渡部　昌
- Journal Title
  
  医学のあゆみ
  
  Volume: 243 Pages: 508-514
- Data Source
  KAKENHI-PROJECT-24890002
[Presentation] がん遺伝子産物PPM1Dのタンパク質分解機構2023
- Author(s)
  渡部昌, 高橋正樹, 畠山　鎮次
- Organizer
  第46回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02690
[Presentation] さまざまなユビキチン結合ドメインを用いたTUBEs (Tandem Ubiquitin-Binding Entities)の作製2022
- Author(s)
  渡部　昌, 畠山鎮次
- Organizer
  第95回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02690
[Presentation] A substrate-trapping strategy to find E3 ubiquitin ligase substrates.2021
- Author(s)
  Watanabe Masashi
- Organizer
  Cold Spring Harbor Laboratory Meeting on the Ubiquitin Family
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22408
[Presentation] A substrate-trapping strategy to find E3 ubiquitin ligase substrates.2021
- Author(s)
  Watanabe Masashi
- Organizer
  Cold Spring Harbor Laboratory Meeting on the Ubiquitin Family
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02690
[Presentation] 基質トラップ戦略によるユビキチンリガーゼParkin、TRIM28の網羅的な基質同定2021
- Author(s)
  渡部　昌, 畠山鎮次
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-19K22408
[Presentation] TRIM28はサイクリンA2のユビキチン化を介しS期への早期進行を抑制する2021
- Author(s)
  渡部　昌, 畠山鎮次
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-21H02690
[Presentation] TRIM28はサイクリンA2のユビキチン化を介しS期への早期進行を抑制する2021
- Author(s)
  渡部　昌, 畠山鎮次
- Organizer
  第94回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K22408
[Presentation] 基質トラップ戦略によるユビキチンリガーゼParkin、TRIM28の網羅的な基質同定2021
- Author(s)
  渡部　昌, 畠山鎮次
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-21H02690
[Presentation] ユビキチン様修飾分子UFM1によるロイコトリエン生合成の制御2020
- Author(s)
  渡部　昌
- Organizer
  第93回日本生化学会大会
- Data Source
  KAKENHI-PROJECT-19K22408
[Presentation] 自然免疫シグナルに関わるユビキチンリガーゼ群の網羅的な基質同定と解析2019
- Author(s)
  渡部　昌
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K22408
[Presentation] 自然免疫シグナルに関わるユビキチンリガーゼ群の網羅的な基質同定と解析2019
- Author(s)
  渡部　昌
- Organizer
  第92回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] Comprehensive identification of E3 ubiquitin ligase substrates by fusion of TUBE and ligase trapping methods.2018
- Author(s)
  Watanabe M
- Organizer
  The 2nd GI-CoRE GSQ, GSB, & IGM JOINT SYMPOSIUM Quantum, Informatics, Biology & Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05989
[Presentation] Comprehensive identification of E3 ubiquitin ligase substrates by fusion of TUBE and ligase trapping methods2018
- Author(s)
  Masashi watanabe, Shigetsugu Hatakeyama
- Organizer
  The 2nd GI-CoRE GSQ, GSB & IGM Joint Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K19506
[Presentation] Comprehensive identification of E3 ubiquitin ligase substrates by fusion of TUBE and ligase trapping methods.2018
- Author(s)
  Watanabe M
- Organizer
  The 2nd GI-CoRE GSQ, GSB, & IGM JOINT SYMPOSIUM Quantum, Informatics, Biology & Medicine
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] Identification of E3 ligase substrates by fusion of TR-TUBE and ligase trap methods.2017
- Author(s)
  Watanabe M
- Organizer
  Cold Spring Harbor Laboratory Meeting on the Ubiquitin Family
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] Identification of E3 ligase substrates by fusion of TR-TUBE and ligase trap methods.2017
- Author(s)
  Watanabe M
- Organizer
  Cold Spring Harbor Laboratory Meeting on the Ubiquitin Family
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-17H05989
[Presentation] ユビキチンE3リガーゼTRIM23は非定型ポリユビキチン化によるPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] ユビキチンリガーゼTRIM23はPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター（北海道・札幌市）
- Year and Date
  2016-03-24
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] ユビキチンE3リガーゼTRIM23は非定型ポリユビキチン化によるPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第68回日本細胞生物学会大会
- Place of Presentation
  京都テルサ（京都府・京都市）
- Year and Date
  2016-06-15
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] ユビキチンリガーゼTRIM23は非定型ポリユビキチン化によるPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学川内北キャンパス（宮城県・仙台市）
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] ユビキチンリガーゼTRIM23はPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] ユビキチンリガーゼTRIM23はPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第89回日本内分泌学会学術総会
- Place of Presentation
  国立京都国際会館（京都府・京都市）
- Year and Date
  2016-04-21
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第39回日本分子生物学会年会
- Place of Presentation
  パシフィコ横浜（神奈川県・横浜市）
- Year and Date
  2016-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-16H06221
[Presentation] ユビキチンリガーゼTRIM23は非定型ポリユビキチン化によるPPARγの安定化を介して脂肪細胞分化を制御する2016
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  第89回日本生化学会大会
- Place of Presentation
  東北大学川内北キャンパス（宮城県・仙台市）
- Year and Date
  2016-09-27
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] The ubiquitin E3 ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARγ.2015
- Author(s)
  Masashi Watanabe
- Organizer
  Cold Spring Harbor Laboratory Meeting on the Ubiquitin Family
- Place of Presentation
  New York(USA)
- Year and Date
  2015-04-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15058
[Presentation] Tripartite motif protein 23 regulates adipocyte differentiation via stabilizing PPARγ2014
- Author(s)
  Masashi Watanabe
- Organizer
  Symposium for young ubiquitin researchers in Japan “New Era in the Ubiquitin Research”
- Place of Presentation
  国際高等研究所
- Year and Date
  2014-11-11
- Data Source
  KAKENHI-PROJECT-25860201
[Presentation] TRIM23 is required for expression of peroxisome proliferator-activated receptor-γ and for subsequent adipocyte differentiation2014
- Author(s)
  Masashi Watanabe, Hidehisa Takahashi, Shigetsugu Hatakeyama
- Organizer
  日本分子生物学会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2014-11-25
- Data Source
  KAKENHI-PROJECT-25860201
[Presentation] TRIMタンパク質による脂肪細胞分化制御2014
- Author(s)
  渡部　昌, 高橋秀尚, 畠山鎮次
- Organizer
  日本生化学会
- Place of Presentation
  国立京都国際会館
- Year and Date
  2014-10-18
- Data Source
  KAKENHI-PROJECT-25860201
[Presentation] Involvement of linear polyubiquitylation in PPARg transcriptional activity2013
- Author(s)
  Masashi Watanabe
- Organizer
  Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  Cold Spring Harbor, New York
- Data Source
  KAKENHI-PROJECT-25860201

1. Hatakeyama Shigetsugu (70294973)

# of Collaborated Projects: 2 results

# of Collaborated Products: 13 results
2. TAKAHASHI Hidehisa (20399819)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
3. 近藤豪 (10712705)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 築山忠維

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
5. 矢部一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 渡辺守

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 土屋輝一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 中丸裕爾

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 高木大

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 秦洋郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 柳輝希

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Watanabe Masashi 渡部 昌

WATANABE masashi 渡部 昌

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がんドライバーユビキチンリガーゼの網羅的基質探索による創薬基盤の確立Principal Investigator

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Functional analysis of cancer driver ubiquitin ligase using a newly developed substrate identification method.Principal Investigator

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Comprehensive identification of polyubiquitinated substrates for elucidation of the "ubiquitin code"Principal Investigator

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自然免疫シグナルにおけるユビキチン化基質の網羅的同定と解析Principal Investigator

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Establishment of method for identification of ubiquitinated protein

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Defense mechanism against lifestyle diseases by ubiquitin-like modifier UFM1Principal Investigator

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Devolopment of a novel method to identify E3 ligase substratesPrincipal Investigator

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Regulation of signal transduction by TRIM family proteins

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The E3 ubiquitin ligase TRIM23 regulates adipocyte differentiation via stabilization of the adipogenic activator PPARgammaPrincipal Investigator

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ユビキチン化による脂質代謝制御転写因子PPARガンマーの活性化制御機構の解明Principal Investigator

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[Book] Advances in Medicine and Biology. Volume 1202017

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[Book] Advances in Medicine and Biology. Volume 1202017

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[Book] Ubiquitin-conjugating enzymes (E2s): Adnances in Medicine and Biology Vol 1202017

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Watanabe Masashi 渡部昌

WATANABE masashi 渡部昌