Makino Tsukasa 牧野司

… Alternative Names

牧野司マキノツカサ

Tsukasa Makino 牧野司

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Researcher Number	10632896
Other IDs
Affiliation (Current)	2026: 東京大学, 大学院医学系研究科(医学部), 特任助教
Affiliation (based on the past Project Information) *help	2023 – 2024: 東京大学, 大学院医学系研究科(医学部), 助教 2015: 東京大学, 医学(系)研究科(研究院), 助教 2014: 独立行政法人理化学研究所, 脳科学総合研究センター, 研究員
Review Section/Research Field	Principal Investigator Basic Section 48010:Anatomy-related / Structural biochemistry
Keywords	Principal Investigator 分子モーター / キネシン / 精子形成 / 男性不妊症 / マンシェット輸送 / 男性不妊 / 鞭毛運動異常 / 細胞骨格・運動 / 構造生物学 / 結晶構造解析 / チューブリン / 微小管 / チューブリン組換え体

Uncovering the 'Manchette motor': A novel transport system for sperm development.Principal Investigator
- Principal Investigator
  
  牧野司
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48010:Anatomy-related
- Research Institution
  The University of Tokyo
Structural basis for the movement of kinesin on microtubulePrincipal Investigator
- Principal Investigator
  
  Tsukasa Makino
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Structural biochemistry
- Research Institution
  The University of Tokyo
  The Institute of Physical and Chemical Research

All 2025 2024 2023 2015

All Journal Article Presentation

[Journal Article] Dimerization of GAS2 mediates crosslinking of microtubules and F-actin2025
- Author(s)
  An Jiancheng、Imasaki Tsuyoshi、Narita Akihiro、Niwa Shinsuke、Sasaki Ryohei、Makino Tsukasa、Nitta Ryo、Kikkawa Masahide
- Journal Title
  
  The EMBO Journal
  
  Volume: - Issue: 10 Pages: 2997-3024
- DOI
  10.1038/s44318-025-00415-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-ORGANIZER-21H05247, KAKENHI-PLANNED-21H05248, KAKENHI-PROJECT-21H04762, KAKENHI-PROJECT-22K06809, KAKENHI-PROJECT-23K27145, KAKENHI-PROJECT-23K06315
[Journal Article] Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping2025
- Author(s)
  Tsukasa Makino、Ryo Kanada、Teppei Mori、Ken-ichi Miyazono、Yuta Komori、Haruaki Yanagisawa、Shoji Takada、Masaru Tanokura、Masahide Kikkawa、Michio Tomishige
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 224 Issue: 7
- DOI
  10.1083/jcb.202501253
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-22H04850, KAKENHI-PROJECT-21H04762, KAKENHI-PROJECT-23K06315
[Journal Article] Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-12024
- Author(s)
  Makino Tsukasa、Kanada Ryo、Mori Teppei、Miyazono Ken-ichi、Komori Yuta、Yanagisawa Haruaki、Takada Shoji、Tanokura Masaru、Kikkawa Masahide、Tomishige Michio
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.09.19.613825
- Open Access
- Data Source
  KAKENHI-PROJECT-23K06315
[Journal Article] Dimerization GAS2 mediates microtubule and F-actin crosslinking2024
- Author(s)
  An Jiancheng、Imasaki Tsuyoshi、Narita Akihiro、Niwa Shinsuke、Sasaki Ryohei、Makino Tsukasa、Nitta Ryo、Kikkawa Masahide
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2024.08.19.608523
- Open Access
- Data Source
  KAKENHI-PROJECT-23K06315
[Journal Article] 増大特集細胞シグナル操作法 Ⅱ.機能からみたシグナル操作法 3.細胞の動態細胞骨格(微小管系)2015
- Author(s)
  牧野司、吉川雅英
- Journal Title
  
  生体の科学
  
  Volume: 66 Issue: 5 Pages: 506-507
- DOI
  10.11477/mf.2425200330
- ISSN
  0370-9531, 1883-5503
- Year and Date
  2015-10-15
- Data Source
  KAKENHI-PROJECT-26840030
[Presentation] べん毛運動とKIF6: ノックアウト・トランスジェニックマウスからの新たな見解2024
- Author(s)
  牧野　司
- Organizer
  顕微鏡学会第80回学術講演会
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] 精子形成におけるマンシェット輸送をになう新たなキネシンモーターの分子機構2024
- Author(s)
  牧野　司
- Organizer
  第129回日本解剖学会総会・全国学術集会
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] KIF6 is essential for male fertility through the ATP production pathway within sperm flagella2024
- Author(s)
  Tsukasa Makino, Chizuru Ito, Takeshi Masuda, Kazuho Ikeda, Daisuke Takao, Yasushi Okada, Kiyotaka Toshimori and Masahide Kikkawa
- Organizer
  21st IUPAB & 62nd BSJ Joint Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] べん毛運動とKIF6: ノックアウト・トランスジェニックマウスからの新たな見解2024
- Author(s)
  牧野司、伊藤千鶴、増田豪、池田一穂、高尾大輔、岡田康志、年森清隆、吉川雅英
- Organizer
  顕微鏡学会第80回学術講演会
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] 二量体化GAS2は微小管とFアクチンの架橋を媒介する2024
- Author(s)
  Jiancheng An, Tsukasa Makino, Tsuyoshi Imasaki, Ryohei Sasaki, Shinsuke Niwa, Irwin Selvam, Akihiro Narita, Ryo Nitta, Masahide Kikkawa
- Organizer
  顕微鏡学会第80回学術講演会
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] Dimerization GAS2 mediates microtubule and F-actin crosslinking2024
- Author(s)
  Jiancheng An, Tsukasa Makino, Tsuyoshi Imasaki, Ryohei Sasaki, Shinsuke Niwa, Irwin Selvam, Akihiro Narita, Ryo Nitta, Masahide Kikkawa
- Organizer
  21st IUPAB & 62nd BSJ Joint Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] KIF6 is essential for male fertility through the ATP production pathway within sperm flagella2024
- Author(s)
  Tsukasa Makino
- Organizer
  21st IUPAB & 62nd BSJ Joint Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06315
[Presentation] Analysis of a Novel Kinesin Motor Involved in Sperm specific Manchette-Transport2023
- Author(s)
  Tsukasa Makino
- Organizer
  第49回内藤コンファレンス
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K06315

1. NITTA Ryo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. TOMISHIGE Michio

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 吉川雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Makino Tsukasa 牧野 司

牧野 司 マキノ ツカサ

Tsukasa Makino 牧野 司

Research Projects

Research Products

Co-Researchers

Uncovering the 'Manchette motor': A novel transport system for sperm development.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural basis for the movement of kinesin on microtubulePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Dimerization of GAS2 mediates crosslinking of microtubules and F-actin2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tension-induced suppression of allosteric conformational changes coordinates kinesin-1 stepping2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Tension-induced suppression of allosteric conformational changes explains coordinated stepping of kinesin-12024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dimerization GAS2 mediates microtubule and F-actin crosslinking2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] 増大特集 細胞シグナル操作法 Ⅱ.機能からみたシグナル操作法 3.細胞の動態 細胞骨格(微小管系)2015

Author(s)

Journal Title

DOI

ISSN

Year and Date

Data Source

[Presentation] べん毛運動とKIF6: ノックアウト・トランスジェニックマウスからの新たな見解2024

Author(s)

Organizer

Data Source

[Presentation] 精子形成におけるマンシェット輸送をになう新たなキネシンモーターの分子機構2024

Author(s)

Organizer

Data Source

[Presentation] KIF6 is essential for male fertility through the ATP production pathway within sperm flagella2024

Author(s)

Organizer

Data Source

[Presentation] べん毛運動とKIF6: ノックアウト・トランスジェニックマウスからの新たな見解2024

Author(s)

Organizer

Data Source

[Presentation] 二量体化GAS2は微小管とFアクチンの架橋を媒介する2024

Author(s)

Organizer

Data Source

[Presentation] Dimerization GAS2 mediates microtubule and F-actin crosslinking2024

Author(s)

Organizer

Data Source

[Presentation] KIF6 is essential for male fertility through the ATP production pathway within sperm flagella2024

Author(s)

Organizer

Data Source

[Presentation] Analysis of a Novel Kinesin Motor Involved in Sperm specific Manchette-Transport2023

Author(s)

Organizer

Data Source

Makino Tsukasa 牧野司

牧野司マキノツカサ

Tsukasa Makino 牧野司

[Journal Article] 増大特集細胞シグナル操作法 Ⅱ.機能からみたシグナル操作法 3.細胞の動態細胞骨格(微小管系)2015