Sugahara Izumi 菅原泉

… Alternative Names

SUGAHARA IZUMI 菅原泉

Yamashita Yzumi

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Researcher Number	10633000
Affiliation (Current)	2023: 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員
Affiliation (based on the past Project Information) *help	2016 – 2017: 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員 2015: 埼玉医科大学, 医学部, 研究員 2015: 埼玉医科大, 医学部, 研究員
Review Section/Research Field	Principal Investigator Life / Health / Medical informatics / Biomedical engineering/Biomaterial science and engineering Except Principal Investigator Orthopaedic surgery / Regenerative medicine
Keywords	Principal Investigator beta cell / single cell analysis / hiPS / single cell / β細胞 / hiPSダブルノックイン Except Principal Investigator 骨代謝 / 糖代謝 / エピジェネティック / 転写因子 … More / 破骨細胞 / 骨芽細胞 / ロコモティブ / エピジェネティクス / Pax6 / 分化 / 遺伝子調節 / 膵β細胞分化 / hiPSレポーター / ケミカルスクリーニング / β細胞 / single cell / double KI hiPSC / iPS細胞 / 膵β細胞 / 化合物スクリーニング Less

Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysisPrincipal Investigator
- Principal Investigator
  
  Sugahara Izumi
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Life / Health / Medical informatics
  Biomedical engineering/Biomaterial science and engineering
- Research Institution
  National Center for Global Health and Medicine
  Saitama Medical University
Molecular insights of the crosstalk between locomotive and metabolic syndromes
- Principal Investigator
  
  Matsumoto Masahito
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Orthopaedic surgery
- Research Institution
  Saitama Medical University
Chemical screening of novel factor to promote beta cell differentiation from hiPS cells
- Principal Investigator
  
  Okazaki Yasushi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Regenerative medicine
- Research Institution
  Saitama Medical University

All 2017 2015 2013

All Journal Article Presentation Patent

[Journal Article] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017
- Author(s)
  Yamashita-Sugahara Y, Matsumoto M, Ohtaka M, Nishimura K, Nakanishi M, Mitani K, Okazaki Y
- Journal Title
  
  Scientific Reports
  
  Volume: 6 Pages: 335908-335908
- DOI
  10.1038/srep35908
- NAID
  120007129280
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K15624, KAKENHI-PROJECT-15K21333
[Journal Article] Family with sequence familarity 57, member B (Fam57b), a novel peroxisome proliferator-activated receptor g target gene that regulates adipogenesis through ceramide synthesis.2013
- Author(s)
  Yamashita-Sugahara Y., Tokuzawa, Y., Nakachi, Y., Knesaki-Yatsuka, Y., Matsumoto, M., Mizuno, Y., Okazaki, Y.
- Journal Title
  
  J. Biol. Chem.
  
  Volume: 288 Pages: 4522-4537
- DOI
  10.1074/jbc.m112.440792
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-25462380
[Patent] 膵内分泌細胞及びその製造方法、並びに分化転換剤2015
- Inventor(s)
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Holder
  松本征仁、岡﨑康司、菅原泉
- Industrial Property Rights Type
  特許
- Filing Date
  2015-07-03
- Overseas
- Data Source
  KAKENHI-PROJECT-25462380
[Presentation] FGFR1阻害剤は膵内分泌前駆細胞（NGN3+)から内分泌細胞への分化を促進する2017
- Author(s)
  Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
- Organizer
  2016日本再生医療学会
- Place of Presentation
  仙台
- Year and Date
  2017-03-07
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017
- Author(s)
  Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
- Organizer
  2017 Miami winter Symposium: Diabetes
- Place of Presentation
  Miami
- Year and Date
  2017-01-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017
- Author(s)
  Yzumi Yamshita-Sugahara
- Organizer
  Miami Winter Symposium 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] FGFR1 阻害剤は膵内分泌前駆細胞（NGN3+）から内分泌細胞への分化を促進する2017
- Author(s)
  菅原　泉
- Organizer
  第14回RCGM国際シンポジウム　埼玉医科大学
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] FGFR1 阻害剤は膵内分泌前駆細胞（NGN3+）から内分泌細胞への分化を促進する2017
- Author(s)
  菅原　泉
- Organizer
  第16回日本再生医療学会総会
- Data Source
  KAKENHI-PROJECT-15K21333
[Presentation] Insulin promoter-Venus/NGN3 promoter-mCherry ダブルノックインhiPS細胞を用いたβ細胞分化誘導の解析2015
- Author(s)
  菅原　泉, 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
- Organizer
  第13回RCGMフロンティアシンポジウム
- Place of Presentation
  埼玉医科大学　創立30周年記念講堂　(埼玉県　日高市）
- Year and Date
  2015-10-30
- Data Source
  KAKENHI-PROJECT-25505003
[Presentation] ヒトiPS細胞におけるヘルパー依存型アデノウィルスを用いたInsulin promoter-Venusレポーター細胞の作製とその解析2013
- Author(s)
  菅原泉　松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
- Organizer
  第11回 RCGMシンポジウム
- Place of Presentation
  埼玉日高市
- Data Source
  KAKENHI-PROJECT-25462380

1. Okazaki Yasushi (80280733)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
2. Matsumoto Masahito (90321819)

# of Collaborated Projects: 3 results

# of Collaborated Products: 6 results
3. Nakachi Yutaka (10522097)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. Watanabe Ami (40611421)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. Nikaido Itoshi (00383290)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. SUDA TATSUO (90014034)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. YASUNAMI YOICHI (00166521)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. SATO TSUYOSHI (60406494)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Sugahara Izumi 菅原 泉

SUGAHARA IZUMI 菅原 泉

Yamashita Yzumi

Research Projects

Research Products

Co-Researchers

Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Molecular insights of the crosstalk between locomotive and metabolic syndromes

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Chemical screening of novel factor to promote beta cell differentiation from hiPS cells

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Family with sequence familarity 57, member B (Fam57b), a novel peroxisome proliferator-activated receptor g target gene that regulates adipogenesis through ceramide synthesis.2013

Author(s)

Journal Title

DOI

Data Source

[Patent] 膵内分泌細胞及びその製造方法、並びに分化転換剤2015

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] FGFR1阻害剤は膵内分泌前駆細胞（NGN3+)から内分泌細胞への分化を促進する2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

Author(s)

Organizer

Data Source

[Presentation] FGFR1 阻害剤は膵内分泌前駆細胞（NGN3+）から内分泌細胞への分化を促進する2017

Author(s)

Organizer

Data Source

[Presentation] FGFR1 阻害剤は膵内分泌前駆細胞（NGN3+）から内分泌細胞への分化を促進する2017

Author(s)

Organizer

Data Source

[Presentation] Insulin promoter-Venus/NGN3 promoter-mCherry ダブルノックインhiPS細胞を用いたβ細胞分化誘導の解析2015

Author(s)

Organizer

Place of Presentation

Year and Date

Data Source

[Presentation] ヒトiPS細胞におけるヘルパー依存型アデノウィルスを用いたInsulin promoter-Venusレポーター細胞の作製とその解析2013

Author(s)

Organizer

Place of Presentation

Data Source

Sugahara Izumi 菅原泉

SUGAHARA IZUMI 菅原泉