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Sugahara Izumi  菅原 泉

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SUGAHARA IZUMI  菅原 泉

Yamashita Yzumi

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Researcher Number 10633000
Affiliation (Current) 2022: 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員
Affiliation (based on the past Project Information) *help 2016 – 2017: 国立研究開発法人国立国際医療研究センター, その他部局等, 研究員
2015: 埼玉医科大学, 医学部, 研究員
2015: 埼玉医科大, 医学部, 研究員
Review Section/Research Field
Principal Investigator
Life / Health / Medical informatics / Biomedical engineering/Biomaterial science and engineering
Except Principal Investigator
Orthopaedic surgery / Regenerative medicine
Keywords
Principal Investigator
beta cell / single cell analysis / hiPS / single cell / β細胞 / hiPSダブルノックイン
Except Principal Investigator
骨代謝 / 糖代謝 / エピジェネティック / 転写因子 … More / 破骨細胞 / 骨芽細胞 / ロコモティブ / エピジェネティクス / Pax6 / 分化 / 遺伝子調節 / 膵β細胞分化 / hiPSレポーター / ケミカルスクリーニング / β細胞 / single cell / double KI hiPSC / iPS細胞 / 膵β細胞 / 化合物スクリーニング Less
  • Research Projects

    (3 results)
  • Research Products

    (10 results)
  • Co-Researchers

    (8 People)
  •  Development and finding the mechanism of pancreatic beta cell differentiation from hiPS cells through Single cell analysisPrincipal Investigator

    • Principal Investigator
      Sugahara Izumi
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Life / Health / Medical informatics
      Biomedical engineering/Biomaterial science and engineering
    • Research Institution
      National Center for Global Health and Medicine
      Saitama Medical University
  •  Molecular insights of the crosstalk between locomotive and metabolic syndromes

    • Principal Investigator
      Matsumoto Masahito
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Orthopaedic surgery
    • Research Institution
      Saitama Medical University
  •  Chemical screening of novel factor to promote beta cell differentiation from hiPS cells

    • Principal Investigator
      Okazaki Yasushi
    • Project Period (FY)
      2013 – 2015
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Regenerative medicine
    • Research Institution
      Saitama Medical University

All 2017 2015 2013

All Journal Article Presentation Patent

  • [Journal Article] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

    • Author(s)
      Yamashita-Sugahara Y, Matsumoto M, Ohtaka M, Nishimura K, Nakanishi M, Mitani K, Okazaki Y
    • Journal Title

      Scientific Reports

      Volume: 6 Pages: 335908-335908

    • DOI

      10.1038/srep35908

    • NAID

      120007129280

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K15624, KAKENHI-PROJECT-15K21333
  • [Journal Article] Family with sequence familarity 57, member B (Fam57b), a novel peroxisome proliferator-activated receptor g target gene that regulates adipogenesis through ceramide synthesis.2013

    • Author(s)
      Yamashita-Sugahara Y., Tokuzawa, Y., Nakachi, Y., Knesaki-Yatsuka, Y., Matsumoto, M., Mizuno, Y., Okazaki, Y.
    • Journal Title

      J. Biol. Chem.

      Volume: 288 Pages: 4522-4537

    • DOI

      10.1074/jbc.m112.440792

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Patent] 膵内分泌細胞及びその製造方法、並びに分化転換剤2015

    • Inventor(s)
      松本征仁、岡﨑康司、菅原泉
    • Industrial Property Rights Holder
      松本征仁、岡﨑康司、菅原泉
    • Industrial Property Rights Type
      特許
    • Filing Date
      2015-07-03
    • Overseas
    • Data Source
      KAKENHI-PROJECT-25462380
  • [Presentation] FGFR1阻害剤は膵内分泌前駆細胞(NGN3+)から内分泌細胞への分化を促進する2017

    • Author(s)
      Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
    • Organizer
      2016日本再生医療学会
    • Place of Presentation
      仙台
    • Year and Date
      2017-03-07
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

    • Author(s)
      Yzumi Yamashita-Sugahara, Masahito Matsumoto,Manami Ohtaka,Ken Nishimura Mahito Nakanishi,Kohnosuke Mitani & Yasushi Okazaki
    • Organizer
      2017 Miami winter Symposium: Diabetes
    • Place of Presentation
      Miami
    • Year and Date
      2017-01-22
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] An inhibitor of fibroblast growth factor receptor-1 (FGFR1) promotes late-stage terminal differentiation from NGN3+ pancreatic endocrine progenitors2017

    • Author(s)
      Yzumi Yamshita-Sugahara
    • Organizer
      Miami Winter Symposium 2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] FGFR1 阻害剤は膵内分泌前駆細胞(NGN3+)から内分泌細胞への分化を促進する2017

    • Author(s)
      菅原 泉
    • Organizer
      第14回RCGM国際シンポジウム 埼玉医科大学
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] FGFR1 阻害剤は膵内分泌前駆細胞(NGN3+)から内分泌細胞への分化を促進する2017

    • Author(s)
      菅原 泉
    • Organizer
      第16回日本再生医療学会総会
    • Data Source
      KAKENHI-PROJECT-15K21333
  • [Presentation] Insulin promoter-Venus/NGN3 promoter-mCherry ダブルノックインhiPS細胞を用いたβ細胞分化誘導の解析2015

    • Author(s)
      菅原 泉, 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
    • Organizer
      第13回RCGMフロンティアシンポジウム
    • Place of Presentation
      埼玉医科大学 創立30周年記念講堂 (埼玉県 日高市)
    • Year and Date
      2015-10-30
    • Data Source
      KAKENHI-PROJECT-25505003
  • [Presentation] ヒトiPS細胞におけるヘルパー依存型アデノウィルスを用いたInsulin promoter-Venusレポーター細胞の作製とその解析2013

    • Author(s)
      菅原泉 松村瞭、佐藤達也、松谷智子、相澤絵美、岩長ゆずる、松本征仁、三谷幸之介、岡崎康司
    • Organizer
      第11回 RCGMシンポジウム
    • Place of Presentation
      埼玉日高市
    • Data Source
      KAKENHI-PROJECT-25462380
  • 1.  Okazaki Yasushi (80280733)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 2.  Matsumoto Masahito (90321819)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 6 results
  • 3.  Nakachi Yutaka (10522097)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 1 results
  • 4.  Watanabe Ami (40611421)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  Nikaido Itoshi (00383290)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  SUDA TATSUO (90014034)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 7.  YASUNAMI YOICHI (00166521)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  SATO TSUYOSHI (60406494)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results

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