Nakahama Taisuke 中濱泰祐

… Alternative Names

中濱泰祐ナカハマタイスケ

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Researcher Number	10636187
Other IDs
Affiliation (Current)	2023: 大阪大学, 大学院医学系研究科, 助教
Affiliation (based on the past Project Information) *help	2016 – 2021: 大阪大学, 医学系研究科, 助教 2015: 大阪大学, 医学(系)研究科(研究院), 特別研究員(PD) 2013: 大阪大学, 学内共同利用施設等, その他 2012: 大阪大学, 免疫学フロンティア研究センター, 特任研究員
Review Section/Research Field	Principal Investigator Immunology / Basic Section 49070:Immunology-related
Keywords	Principal Investigator RNA編集 / 自己免疫疾患 / microRNA / Th17 / AHR / autoimmune disease / T細胞 / RNA編集酵素 / T細胞成熟 / Adar1 … More / 獲得免疫 / ADAR1 / AGS / 脳症 / MDA5 / エカルディ・グティエール症候群 Less

RNA編集不全によって引き起こされる遺伝性脳症の病態形成機構の解明Principal Investigator
- Principal Investigator
  
  中濱泰祐
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
Elucidation of the mechanism underlying the regulation of adaptive immunity by endogenous double-stranded RNAPrincipal Investigator
- Principal Investigator
  
  Nakahama Taisuke
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 49070:Immunology-related
- Research Institution
  Osaka University
The role of RNA editing in Th17 cell differentiationPrincipal Investigator
- Principal Investigator
  
  Nakahama Taisuke
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Immunology
- Research Institution
  Osaka University
AhrによるmicroRNAの発現調節を介したTh17細胞の分化制御機構の解析Principal Investigator
- Principal Investigator
  
  中濱泰祐
- Project Period (FY)
  2012 – 2013
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Immunology
- Research Institution
  Osaka University

All 2021 2020 2019 2018 2017 2016 2012

All Journal Article Presentation

[Journal Article] Deciphering the Biological Significance of ADAR1-Z-RNA Interactions2021
- Author(s)
  Nakahama Taisuke、Kawahara Yukio
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 22 Pages: 11435-11435
- DOI
  10.3390/ijms222111435
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-21K07080
[Journal Article] An Aicardi-Goutieres syndrome-causative point mutation in Adar1 gene invokes multi-organ inflammation and late-onset encephalopathy in mice2021
- Author(s)
  Inoue Maal、Nakahama Taisuke、Yamasaki Ryuichiro、Shibuya Toshiharu、Kim Jung In、Todo Hiroyuki、Xing Yanfang、Kato Yuki、Morii Eiichi、Kawahara Yukio
- Journal Title
  
  The Journal of Immunology
  
  Volume: 207 Pages: 3016-3027
- DOI
  10.4049/jimmunol.2100526
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-20J11266, KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-21K12109
[Journal Article] RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.2021
- Author(s)
  Jung In Kim, Taisuke Nakahama, Ryuichiro Yamasaki, Pedro Henrique Costa Cruz, Tuangtong Vongpipatana, Maal Inoue, Nao Kanou, Yanfang Xing, Hiroyuki Todo, Toshiharu Shibuya, Yuki Kato, Yukio Kawahara.
- Journal Title
  
  PLoS Genet
  
  Volume: 未定(In Press)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K15186
[Journal Article] Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA editing induce Aicardi-Goutieres syndrome-like encephalopathy2021
- Author(s)
  Nakahama Taisuke、Kato Yuki、Shibuya Toshiharu、Inoue Maal、Kim Jung In、Vongpipatana Tuangtong、Todo Hiroyuki、Xing Yanfang、Kawahara Yukio
- Journal Title
  
  Immunity
  
  Volume: 54 Pages: 1976-1988
- DOI
  10.1016/j.immuni.2021.08.022
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03341, KAKENHI-PROJECT-20J11266, KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-21K07080, KAKENHI-PROJECT-21K12109
[Journal Article] Adenosine-to-inosine RNA editing in the immune system: friend or foe?2020
- Author(s)
  Nakahama Taisuke、Kawahara Yukio
- Journal Title
  
  Cellular and Molecular Life Sciences
  
  Volume: -
- DOI
  10.1007/s00018-020-03466-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15186
[Journal Article] A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing2020
- Author(s)
  Pedro Henrique Costa Cruz, Yuki Kato, Taisuke Nakahama, Toshiharu Shibuya, Yukio Kawahara
- Journal Title
  
  RNA
  
  Volume: 26(4) Pages: 454-469
- DOI
  10.1261/rna.072728.119
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22580, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-18K11526
[Journal Article] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2020
- Author(s)
  Vongpipatana T, Nakahama T, Shibuya T, Kato Y, Kawahara Y
- Journal Title
  
  The Journal of Immunology
  
  Volume: 204(8) Pages: 2156-2168
- DOI
  10.4049/jimmunol.1900929
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22580, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-18J11733, KAKENHI-PROJECT-18K11526
[Journal Article] ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity.2018
- Author(s)
  Nakahama T, Kato Y, Kim JI, Vongpipatana T, Suzuki Y, Walkley CR, Kawahara Y.
- Journal Title
  
  EMBO Reports
  
  Volume: 19
- DOI
  10.15252/embr.201846303
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11526, KAKENHI-PROJECT-18K15186, KAKENHI-PROJECT-16H05320, KAKENHI-PROJECT-18J11733, KAKENHI-PROJECT-17K19352, KAKENHI-PROJECT-16H06279
[Journal Article] Expression of aryl hydrocarbon receptor, inflammatory cytokines, and incidence of rheumatoid arthritis in Vietnamese dioxin-exposed people.2017
- Author(s)
  Nguyen CH, Nakahama T, Dang TT, Chu HH, Van Hoang L, Kishimoto T, Nguyen NT.
- Journal Title
  
  J Immunotoxicol
  
  Volume: 14 Pages: 196-203
- DOI
  10.1080/1547691x.2017.1377323
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19126
[Journal Article] Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblon via suppression of the TRIF/IRF3 pathway2016
- Author(s)
  Millrine D, Haruhiko M, Tei M, Dubey P, Kishan N, Nakahama T, Gemechu Y, Ripley B, Kishimoto T.
- Journal Title
  
  Int Immunol
  
  Volume: 印刷中 Pages: 307-315
- DOI
  10.1093/intimm/dxw005
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-13J05768, KAKENHI-PROJECT-15K19126
[Presentation] Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice2021
- Author(s)
  Taisuke Nakahama, Yukio Kawahara
- Organizer
  第50回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice2021
- Author(s)
  Taisuke Nakahama, Yuki Kato, Toshiharu Shibuya, Maal Inoue, Jung In Kim, Tuangtong Vongpipatana, Hiroyuki Todo, Yanfang Xing, Yukio Kawahara
- Organizer
  第22回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-21K07080
[Presentation] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2019
- Author(s)
  Taisuke Nakahama, Tuangtong Vogpipatana, Yuki Kato and Yukio Kawahara
- Organizer
  RNA 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2019
- Author(s)
  Taisuke Nakahama, Tuangtong Vogpipatana, Toshiharu Shibuya, Yuki Kato Yukio Kawahara
- Organizer
  第21回日本RNA学会年会
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1-mediated RNA editing is required for thymic self-tolerance and prevention of autoimmunity2019
- Author(s)
  Nakahama Taisuke
- Organizer
  第20回武田科学振興財団生命科学シンポジウム「RNAネオバイオロジー」
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity2019
- Author(s)
  Nakahama Taisuke
- Organizer
  Gordon Research Seminar for RNA editing (イタリア)（国際学会）
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] 中枢性免疫寛容成立におけるRNA編集の役割の解明2018
- Author(s)
  中濱泰祐
- Organizer
  「先進ゲノム支援」2018年度拡大班会議
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] T細胞成熟におけるRNA編集の役割の解明2018
- Author(s)
  中濱泰祐
- Organizer
  先進ゲノム支援　2017年度拡大班会議
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] ADAR1によるRNA編集を介した自己免疫制御機構2018
- Author(s)
  中濱泰祐
- Organizer
  第11回若手フォーラム
- Data Source
  KAKENHI-PROJECT-18K15186
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley, Yukio Kawahara
- Organizer
  Gordon Research Conferences - 2017 Meeting - RNA editing
- Place of Presentation
  Ventura, California, United States
- Year and Date
  2017-03-12
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for e arly T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley and Yukio Kawahara
- Organizer
  The 43rd Naito Conference
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2017
- Author(s)
  Taisuke Nakahama, Carl Walkley and Yukio Kawahara
- Organizer
  RNAフロンティアミーティング 2017
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] RNA editing-mediated prevention of activating MDA5 pathway is required for early T cell development2016
- Author(s)
  Taisuke Nakahama, Carl Walkley, Yukio Kawahara
- Organizer
  第45回日本免疫学会学術集会
- Place of Presentation
  沖縄
- Year and Date
  2016-12-05
- Data Source
  KAKENHI-PROJECT-15K19126
[Presentation] AHR-mediated induction of miR-132/212 cluster enhances TH17 cell differentiation2012
- Author(s)
  Taisuke Nakahama
- Organizer
  日本免疫学会学術集会
- Place of Presentation
  神戸国際展示場
- Data Source
  KAKENHI-PROJECT-24890107

1. KATO Yuki

# of Collaborated Projects: 0 results

# of Collaborated Products: 5 results
2. SUZUKI Hiromu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 河原行郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 6 results
4. KIM JUNG IN

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. 鈴木穣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. VONGPIPATANA TUANGTONG

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 加藤和人

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Nakahama Taisuke 中濱 泰祐

中濱 泰祐 ナカハマ タイスケ

Research Projects

Research Products

Co-Researchers

RNA編集不全によって引き起こされる遺伝性脳症の病態形成機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the mechanism underlying the regulation of adaptive immunity by endogenous double-stranded RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of RNA editing in Th17 cell differentiationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

AhrによるmicroRNAの発現調節を介したTh17細胞の分化制御機構の解析Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Deciphering the Biological Significance of ADAR1-Z-RNA Interactions2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An Aicardi-Goutieres syndrome-causative point mutation in Adar1 gene invokes multi-organ inflammation and late-onset encephalopathy in mice2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.2021

Author(s)

Journal Title

Data Source

[Journal Article] Mutations in the adenosine deaminase ADAR1 that prevent endogenous Z-RNA editing induce Aicardi-Goutieres syndrome-like encephalopathy2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adenosine-to-inosine RNA editing in the immune system: friend or foe?2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A comparative analysis of ADAR mutant mice reveals site-specific regulation of RNA editing2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAR1 regulates early T cell development via MDA5-dependent and -independent pathways2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ADAR1-mediated RNA editing is required for thymic self-tolerance and inhibition of autoimmunity.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Expression of aryl hydrocarbon receptor, inflammatory cytokines, and incidence of rheumatoid arthritis in Vietnamese dioxin-exposed people.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Immunomodulatory drugs inhibit TLR4-induced type-1 interferon production independently of Cereblon via suppression of the TRIF/IRF3 pathway2016

Author(s)

Journal Title

DOI

Data Source

[Presentation] Disruption of Z-RNA-binding of ADAR1 induces Aicardi-Goutieres syndrome-like encephalopathy in mice2021

Author(s)

Nakahama Taisuke 中濱泰祐

中濱泰祐ナカハマタイスケ