INOUE Hirofumi 井上博文

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Inoue Hirofumi 井上博文

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Researcher Number	10639305
Other IDs
Affiliation (Current)	2025: 東京農業大学, 応用生物科学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 東京農業大学, 応用生物科学部, 准教授 2013 – 2019: 東京農業大学, 応用生物科学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 38050:Food sciences-related / Basic Section 08030:Family and consumer sciences, and culture and living-related / Applied health science / Eating habits Except Principal Investigator Basic Section 08030:Family and consumer sciences, and culture and living-related / Basic Section 38050:Food sciences-related / Eating habits
Keywords	Principal Investigator 鉄欠乏 / 骨代謝 / 老化 / オートファジー / 妊娠胎生期 / 脳内炎症 / 神経伸長 / トリプトファン / 脳機能 / PRMTs … More / タンパク質のメチル化 / PRMT / 肝臓 / メチル基転移酵素 / メチル化 / ビタミンD3 / 脂溶性ビタミン / 細胞老化 / 活性酸素種 / ビタミンD / ビタミンC / 炎症性疾患 / 金属トランスポーター / 活性酸素 / 酸化ストレス … More Except Principal Investigator メタボリックシンドローム / ロコモティブシンドローム / 細胞内小胞輸送 / コレステロール / 生活習慣病 / マグネシウム / 糖尿病 / ルシフェラーゼアッセイ / 発酵産物 / 米麹発酵産物 / 代謝産物 / 腸内細菌 / equol / 水素(H+) / UCP-1 / SMP30 / equol鏡像異性体 / 腸内細菌代謝産物 / 植物性機能物質 / 生理活性物質 / 植物性機能物質(フィトケミカル) / 骨粗鬆症 / フィトケミカル / シグナル伝達 / 破骨細胞 / 炎症制御 / 含硫化合物 / ポリフェノール / ファイトケミカル Less

Importance of Magnesium in Diabetes Mellitus: Toward Establishing Methods of Prevention and Improvement
- Principal Investigator
  
  萩原真
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  University of Niigata Prefecture
妊娠胎生期の鉄欠乏状態が生後の大脳皮質組織異常と脳内炎症に及ぼす影響Principal Investigator
- Principal Investigator
  
  井上博文
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture
Controls of inflammation and intestinal environment by intestinal bacterial metabolites for extending healthy life expectancy
- Principal Investigator
  
  Uehara Mariko
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38050:Food sciences-related
- Research Institution
  Tokyo University of Agriculture
Bone-Specific Epigenetic Changes via Vitamin B 12 Metabolism under Iron Deficiency ConditionsPrincipal Investigator
- Principal Investigator
  
  Inoue Hirofumi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 08030:Family and consumer sciences, and culture and living-related
- Research Institution
  Tokyo University of Agriculture
Effects of iron deficiency on the vitamin metabolites and age-related diseasesPrincipal Investigator
- Principal Investigator
  
  INOUE Hirofumi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Applied health science
- Research Institution
  Tokyo University of Agriculture
Mechanisms of inflammation control in functional phytochemicals: Counterplans against lifestyle-related diseases based on chronic inflammation
- Principal Investigator
  
  UEHARA Mariko
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Research Field
  
  Eating habits
- Research Institution
  Tokyo University of Agriculture
Effects of mineral deficiency diet on between aging-disease and reactive oxygen signalPrincipal Investigator
- Principal Investigator
  
  Inoue Hirofumi
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Eating habits
- Research Institution
  Tokyo University of Agriculture

All 2024 2023 2022 2021 2020 2019 2018 2017 2016 2015 2013 Other

All Journal Article Presentation Book

[Book] ポリフェノールの科学（Ⅱ. ポリフェノールの健康機能　9. ロコモティブシンドロームの予防　9.1 骨）2023
- Author(s)
  上原万里子、高橋信之、井上博文
- Total Pages
  214
- Publisher
  朝倉書店
- ISBN
  9784254103038
- Data Source
  KAKENHI-PROJECT-20H02938
[Journal Article] A modified system using macrophage-conditioned medium revealed that the indirect effects of anti-inflammatory food-derived compounds improve inflammation-induced suppression of UCP-1 mRNA expression in 10T1/2 adipocytes2024
- Author(s)
  Takahashi H, Morikawa M, Ozaki E, Numasaki M, Morimoto H, Tanaka M, Inoue H, Goto T, Kawada T, Eguchi F, Uehara M, Takahashi N.
- Journal Title
  
  Biosci Biotechnol Biochem (ahead of print)
  
  Volume: ー Issue: 6 Pages: 900-903
- DOI
  10.1093/bbb/zbae033
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02938, KAKENHI-PROJECT-21H02146
[Journal Article] Prevention of Metabolic Syndrome and Locomotive Syndrome Using Food Factors Targeting Chronic Inflammation2024
- Author(s)
  田中未央里、飯田薫子、井上博文、高橋信之、上原万里子
- Journal Title
  
  Nippon Eiyo Shokuryo Gakkaishi
  
  Volume: 77 Issue: 2 Pages: 117-124
- DOI
  10.4327/jsnfs.77.117
- ISSN
  0287-3516, 1883-2849
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02938, KAKENHI-PROJECT-21H02146
[Journal Article] Mechanism of Lipid Metabolism Abnormalities Resulting in Obesity, Diabetes, and Postprandial Hyperlipidemia2024
- Author(s)
  高橋信之、高橋尚子、森本洋武、井上博文、後藤剛、河田照雄、上原万里子
- Journal Title
  
  Nippon Eiyo Shokuryo Gakkaishi
  
  Volume: 77 Issue: 2 Pages: 109-115
- DOI
  10.4327/jsnfs.77.109
- ISSN
  0287-3516, 1883-2849
- Language
  Japanese
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02938, KAKENHI-PROJECT-21H02146
[Journal Article] AMPK negatively regulates RANKL-induced osteoclast differentiation by controlling oxidative stress2023
- Author(s)
  Tanaka Miori、Inoue Hirofumi、Takahashi Nobuyuki、Uehara Mariko
- Journal Title
  
  Free Radical Biology and Medicine
  
  Volume: 205 Pages: 107-115
- DOI
  10.1016/j.freeradbiomed.2023.05.033
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17646, KAKENHI-PROJECT-20H02938
[Journal Article] Resveratrol Upregulates Senescence Marker Protein 30 by Activating AMPK/Sirt1-Foxo1 Signals and Attenuating H2O2-Induced Damage in FAO Rat Liver Cells2023
- Author(s)
 Inoue H, Shimizu Y, Yoshikawa H, Arakawa K, Tanaka M, Morimoto H, Sato A, Takino Y, Ishigami A, Takahashi N, Uehara M.
- Journal Title
 
 Journal of Nutritional Science and Vitaminology
 
 Volume: 69 Issue: 5 Pages: 388-393
- DOI
 10.3177/jnsv.69.388
- ISSN
 0301-4800, 1881-7742
- Year and Date
 2023-10-31
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20H02938, KAKENHI-PROJECT-23K24804
[Journal Article] (S)-Equol Is More Effective than (R)-Equol in Inhibiting Osteoclast Formation and Enhancing Osteoclast Apoptosis, and Reduces Estrogen Deficiency?Induced Bone Loss in Mice2022
- Author(s)
  Tanaka Miori、Fujii Shungo、Inoue Hirofumi、Takahashi Nobuyuki、Ishimi Yoshiko、Uehara Mariko
- Journal Title
  
  The Journal of Nutrition
  
  Volume: 152 Issue: 8 Pages: 1831-1842
- DOI
  10.1093/jn/nxac130
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K17646, KAKENHI-PROJECT-20H02938
[Journal Article] Erucin inhibits osteoclast formation via suppressing cell?cell fusion molecule DC-STAMP without influencing mineralization by osteoblasts2022
- Author(s)
  Takagi Tomohiro、Inoue Hirofumi、Fujii Shungo、Takahashi Nobuyuki、Uehara Mariko
- Journal Title
  
  BMC Research Notes
  
  Volume: 15 Issue: 1 Pages: 1-6
- DOI
  10.1186/s13104-022-05988-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20H02938
[Journal Article] Dietary magnesium deficiency induces the expression of neuroinflammation-related genes in mouse brain2021
- Author(s)
  R. Tsuji, H. Inoue, M. Uehara, S. Kida
- Journal Title
  
  Neuropsychopharmacology Reports
  
  Volume: - Issue: 2 Pages: 230-236
- DOI
  10.1002/npr2.12167
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02302, KAKENHI-PUBLICLY-19H04917, KAKENHI-PLANNED-18H05434, KAKENHI-PROJECT-18H03944, KAKENHI-PROJECT-20K21265, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-19H01047
[Journal Article] Upregulation and stabilization of senescence marker protein-30 by epigallocatechin gallate against tert-butyl hydroperoxide-induced liver injury in vitro and in vivo2021
- Author(s)
 Inoue Hirofumi、Arakawa Kohta、 Tanaka Miori、 Katsumata-Tsuboi Rie、Takahashi Nobuyuki、Uehara Mariko
- Journal Title
 
 Journal of Clinical Biochemistry and Nutrition
 
 Volume: 68 Issue: 1 Pages: 51-57
- DOI
 10.3164/jcbn.20-119
- NAID
 130007965277
- ISSN
 0912-0009, 1880-5086
- Language
 English
- Peer Reviewed / Open Access
- Data Source
 KAKENHI-PROJECT-20H02938
[Journal Article] Iron deficiency negatively regulates protein methylation via the downregulation of protein arginine methyltransferase2020
- Author(s)
  H. Inoue, N. Hanawa, SI. Katsumata, Y. Aizawa, R.Katsumata-Tsuboi, M. Tanaka, N. Takahashi, M. Uehara
- Journal Title
  
  Heliyon
  
  Volume: 10 Issue: 10 Pages: e05059-e05059
- DOI
  10.1016/j.heliyon.2020.e05059
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K02302
[Journal Article] Down-regulation of senescence marker protein 30 by iron-specific chelator deferoxamine drives cell senescence.2018
- Author(s)
  H. Inoue, N. Hanawa, S. Katsumata, R. Katsumata-Tsuboi, N. Takahashi, M. Uehara
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 82 Issue: 5 Pages: 900-903
- DOI
  10.1080/09168451.2018.1440190
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16609
[Journal Article] Downregulation of senescence marker protein 30 by iron-specific chelator deferoxamine deferoxamine drives cell senescence.2018
- Author(s)
  H. Inoue, N. Hanawa, S. Katsumata, R. Katsumata-Tsuboi, N. Takahashi, M. Uehara
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 82 Pages: 900-903
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K16609
[Journal Article] Extracts of black and brown rice powders improve hepatic lipid accumulation via the activation of PPARα in obese and diabetic model mice.2017
- Author(s)
  Felix AD, Takahashi N, Takahashi M, Katsumata-Tsuboi R, Satoh R, Soon Hui T, Miyajima K, Nakae D, Inoue H, Uehara M.
- Journal Title
  
  Biosci Biotechnol Biochem.
  
  Volume: 81 Issue: 11 Pages: 2209-2211
- DOI
  10.1080/09168451.2017.1372178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15H01767
[Journal Article] Sulforaphane inhibits osteoclast differentiation by suppressing the cell-cell fusion molecules DC-STAMP and OC-STAMP.2017
- Author(s)
  Takagi T, Inoue H, Takahashi N, Katsumata-Tsuboi R, Uehara M.
- Journal Title
  
  Biochem. Biophys. Res. Commun.
  
  Volume: 483 Issue: 1 Pages: 718-724
- DOI
  10.1016/j.bbrc.2016.12.075
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H01767
[Journal Article] Iron deficiency induces autophagy and activates Nrf2 signal through modulating p62/SQSTM 2017
- Author(s)
 Inoue H, Hanawa N, Katsumata SI, Katsumata-Tsuboi R, Takahashi N, Uehara M.
- Journal Title
 
 Biomed. Res.
 
 Volume: 38 Issue: 6 Pages: 343-350
- DOI
 10.2220/biomedres.38.343
- NAID
 130006248352
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed
- Data Source
 KAKENHI-PROJECT-16K16609
[Journal Article] Sulforaphene attenuates multinucleation of pre-osteoclasts by suppressing expression of cell-cell fusion-associated genes DC-STAMP, OC-STAMP, and Atp6v0d2.2017
- Author(s)
  Takagi T, Inoue H, Takahashi N, Katsumata-Tsuboi R, Uehara M.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 81 Issue: 6 Pages: 1220-1223
- DOI
  10.1080/09168451.2017.1281729
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15H01767
[Journal Article] A combination of soy isoflavones and cello-oligosaccharides changes equol/O-desmethylangolensin production ratio and attenuates bone fragility in ovariectomized mice.2016
- Author(s)
  Fujii S, Takahashi N, Inoue H, Katsumata S, Kikkawa Y, Machida M, Ishimi Y, Uehara M.
- Journal Title
  
  Biosci. Biotechnol. Biochem.
  
  Volume: 80 Issue: 8 Pages: 1632-1635
- DOI
  10.1080/09168451.2016.1184559
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H01767
[Journal Article] Activation of Nrf2/Keap1 Signaling and Autophagy Induction against Oxidative Stress in Heart in Iron Deficiency2015
- Author(s)
  Hirofumi Inoue, Ken-Ichi Kobayashi, Moussa Ndong, Yuji Yamamoto, Shi-Ichi Katsumata, Kazuharu Suzuki, Mariko Uehara
- Journal Title
  
  Bioscience, Biotechnology, and Biochemistry
  
  Volume: 60 Issue: 8 Pages: 1-3
- DOI
  10.1080/09168451.2015.1018125
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-25750057, KAKENHI-PROJECT-15H01767, KAKENHI-PROJECT-25450181
[Presentation] ベージュ脂肪細胞におけるアドレナリン感受性を増強する食品成分の機能解析2024
- Author(s)
  高橋尚子、沼崎南、井上博文、森本洋武、後藤剛、河田照雄、江口文陽、上原万里子、高橋信之
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 褐色様脂肪細胞機能阻害に対する抗炎症食品成分の作用評価2023
- Author(s)
  高橋尚子、楢原さゆり、三輪拓美、森本洋武、井上博文、後藤剛、河田照雄、上原万里子、高橋信之
- Organizer
  日本農芸化学会2023年度大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] キノコ抽出物の抗炎症作用による脂肪細胞機能阻害の回復効果2023
- Author(s)
  三輪拓美、高橋尚子、江口文陽、森本洋武、井上博文、上原万里子、高橋信之
- Organizer
  第28回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] ハトムギ抽出物の抗炎症作用の検討2023
- Author(s)
  楢原さゆり、高橋尚子、紙居真央、森本洋武、井上博文、稲垣一弥、横林研太郎、上原万里子、髙橋信之
- Organizer
  第28回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 抗加齢タンパク質SMP30はAPAP誘発急性肝障害時に細胞外へ放出される2023
- Author(s)
  荒川航太、井上博文、石神昭人、佐藤綾美、滝野有花、美谷島克宏、大橋清佳、森本洋武、高橋信之、上原万里子
- Organizer
  第28回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 褐色様脂肪細胞におけるブラックジンジャー抽出物によるUCP-1発現増強2023
- Author(s)
  高橋尚子、楢原さゆり、三輪拓美、森本洋武、井上博文、後藤剛、河田照雄、上原万里子、高橋信之
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] アスコルビン酸欠乏レベルの違いが抗老化タンパク質加齢指標タンパク質-30 (SMP30)発現のエクソソーム分泌に与える影響2023
- Author(s)
  荒川航太、井上博文、石神昭人、佐藤綾美、滝野有花、森本洋武、高橋信之、上原万里子
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] ブラックジンジャー抽出物によるベージュ脂肪細胞の活性化2023
- Author(s)
  高橋尚子、楢原さゆり、三輪拓美、森本洋武、井上博文、後藤剛、河田照雄、上原万里子、高橋信之
- Organizer
  第28回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] タンパク質分解産物の抗炎症作用の解析2023
- Author(s)
  太田彩水、尾崎映見、高橋尚子、森本洋武、井上博文、上原万里子、高橋信之
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] AMPKの活性化を介した食後高脂血症悪化の改善2023
- Author(s)
  八尾成美、楢原さゆり、木村優人、富島七海、高橋尚子、森本洋武、井上博文、上原万里子、高橋信之
- Organizer
  第77回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 抗炎症作用を有するショウガ含有成分による褐色様脂肪細胞機能阻害の回復2022
- Author(s)
  高橋尚子、楢原さゆり、三輪拓美、森本洋武、井上博文、後藤剛、河田照雄、上原万里子、高橋信之
- Organizer
  第27回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 鉄欠乏状態における活性酸素シグナルとビタミン類代謝の変動2022
- Author(s)
  井上博文
- Organizer
  第76回日本栄養・食糧学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] 飽和脂肪酸ならびに不飽和脂肪酸が破骨細胞分化に及ぼす影響の差異2022
- Author(s)
  田中未央里、赤松則千夏、高橋尚子、伊藤圭汰、君羅好史、井上博文、高橋信之、上原万里子
- Organizer
  第76回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 緑茶カテキンEGCGによる抗加齢タンパク質SMP30発現制御はproteasome活性阻害を介し67LR非依存的である2022
- Author(s)
  荒川航太, 井上博文, 石神昭人, 佐藤綾美, 滝野有花, 森本洋武, 田中未央里, 高橋信之, 上原万里子
- Organizer
  日本農芸化学会 2022年大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 緑茶カテキン EGCG による抗加齢タンパク質 SMP30 発現増加はUbiquitin-proteasome 活性の抑制を介する2021
- Author(s)
  荒川航太，井上博文，田中未央里, 高橋信之,上原万里子
- Organizer
  第14回日本ポリフェノール学会第14回大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] レスベラトロールは AMPK 活性を介して抗老化タンパク質 SMP30 発現を増加させる2021
- Author(s)
  清水祐作、吉川洸人、荒川航太、田中未央里、井上博文、高橋信之、上原万里子
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 抗炎症作用を持つ食品成分の骨代謝に対する作用の解析ーショウガ麹の効果ー2021
- Author(s)
  伊藤圭汰, 伊東侑亮, 田中未央里, 井上博文, 井口隆文, 瀬川貴之, 常勇進, 高橋信之, 上原万里子
- Organizer
  第26回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] レスベラトロールによる抗老化タンパク質 SMP30 発現増加は AMPK-Foxo1 経路に依存する2021
- Author(s)
  清水祐作, 吉川洸人, 荒川航太, 田中未央里, 井上博文, 高橋信之, 上原万里子
- Organizer
  第26回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] AMPK を介した食品因子による破骨細胞分化制御機構の解明2021
- Author(s)
  田中未央里、井上博文、高橋信之、上原万里子
- Organizer
  第75回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 炎症による熱産生阻害に対する抗炎症作用を持つ食品成分の機能解析ー新規食品成分評価系の構築ー2021
- Author(s)
  高橋尚子, 尾崎映見, 井上博文, 田中未央里, 後藤剛, 河田照雄, 上原万里子, 高橋信之
- Organizer
  第26回日本フードファクター学会学術集会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 転写因子レポーター細胞を用いた破骨細胞分化評価系の確立2020
- Author(s)
  伊東侑亮, 高橋信之, 森川未織, 田中未央里, 井上博文, 上原万里子
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 褐色脂肪細胞の炎症による不活性化を抑える食品機能性成分探索系の確立2020
- Author(s)
  森川未織, 伊東侑亮, 田中未央里, 井上博文, 後藤剛, 河田照雄, 上原万里子, 高橋信之
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] エクオール鏡像異性体による破骨細胞分化抑制メカニズムの検討2020
- Author(s)
  田中未央里，井上博文，高橋信之，石見佳子，上原万里子
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] エクオール鏡像異性体の骨代謝制御作用に関する検討2020
- Author(s)
  田中未央里，井上博文，高橋信之，石見佳子，上原万里子
- Organizer
  第25回日本フードファクター学会学術集会(日本農芸化学会西日本支部との合同大会)
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 鉄欠乏状態による骨脆弱化とビタミン類の体内変動2020
- Author(s)
  井上博文、勝間田真一、斎藤彰宏、勝間田(坪井)理恵、田中未央里、高橋信之、上原万里子
- Organizer
  レドックス・ライフイノベーション第170委員会 20周年記念若手シンポジウム
- Invited
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] 緑茶カテキンEGCGは抗加齢タンパク質SMP30の安定化を促進することで抗老化能を発揮する2020
- Author(s)
  井上博文, 荒川航太, 田中未央里, 高橋信之, 上原万里子
- Organizer
  第74回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-20H02938
[Presentation] 鉄欠乏状態はタンパク質メチル化修飾を負に制御する2019
- Author(s)
  井上博文、勝間田(坪井) 理恵、田中未央里、高橋信之、上原万里子
- Organizer
  第３０回日本微量元素学会学術集会
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] Effects of iron deficiency on reactive oxygen species and intracellular homeostasis2019
- Author(s)
  Hirofumi Inoue, Shin-Ichi Katsumata, Rie Katsumata-Tsuboi, Miori Tanaka, Nobuyuki Takahashi, Mariko Uehara
- Organizer
  The 7th International Conference on Food Factors
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] 鉄欠乏状態はPRMT1発現の減少を介してタンパク質メチル化修飾を減弱させる2019
- Author(s)
  井上博文、塙信彰、勝間田真一、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第73回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] 鉄欠乏状態がタンパク質のメチル化修飾に及ぼす影響2019
- Author(s)
  井上博文、勝間田(坪井) 理恵、田中未央里、高橋信之、上原万里子
- Organizer
  第58回日本食生活学会
- Data Source
  KAKENHI-PROJECT-19K02302
[Presentation] 鉄欠乏状態における細胞老化と抗加齢タンパク質SMP30の役割2018
- Author(s)
  井上博文、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第57回日本食生活学会
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] 骨粗鬆症予防におけるフィトケミカルの有効性2017
- Author(s)
  井上博文
- Organizer
  第15回日本機能性食品医用学会総会
- Invited
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 鉄欠乏状態はERK1/2を介して抗加齢タンパク質SMP30の発現を抑制する2017
- Author(s)
  井上博文、塙信彰、勝間田真一、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] レスベラトロールの食後高脂血症に対する作用メカニズムの解析2017
- Author(s)
  高橋真美、佐藤綾、勝間田理恵、井上博文、中田理恵子、井上裕康、河田照雄、室田佳恵子、上原万里子、高橋信之
- Organizer
  第71回日本栄養・食糧学会大会
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 鉄欠乏状態における活性酸素種と抗加齢タンパク質SMP30の生理的役割2017
- Author(s)
  井上博文、勝間田真一、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第39回日本臨床栄養学会総会・第38回日本臨床栄養協会総会　第15回大連合大会
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] DNAマイクロアレイ法を用いた鉄欠乏状態と酸化ストレスを結ぶ新規分子の探索2017
- Author(s)
  井上博文、塙信彰、勝間田真一、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第10回食香粧研究会
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] SulforaphaneはSTAT1を介して破骨細胞融合因子(DC-STAMP，OC-STAMP)を阻害する2016
- Author(s)
  髙木智弘、井上博文、勝間田(坪井)理恵、高橋信之、上原万里子
- Organizer
  第21回日本フードファクター学会学術集会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 僕がこの研究をはじめた理由：必須微量元素とフードファクターを結ぶ2016
- Author(s)
  井上博文
- Organizer
  フードサイエンスフォーラム第22回学術集会
- Place of Presentation
  岡山県美作市　美春閤
- Year and Date
  2016-09-08
- Invited
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] 鉄欠乏状態は酸化ストレスを惹起することで細胞老化を誘導する2016
- Author(s)
  井上博文、小林謙一、鈴木司、山本祐司、勝間田真一、勝間田(坪井)理恵、高橋信之、上原万里子
- Organizer
  第70回日本栄養食糧学会大会
- Place of Presentation
  兵庫県西宮市　武庫川女子大学　中央キャンパス
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] 鉄欠乏状態が細胞老化と細胞内浄化機構オートファジーに及ぼす影響2016
- Author(s)
  井上博文、小林謙一、鈴木司、山本祐司、勝間田真一、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  日本農芸化学会2016年度大会
- Place of Presentation
  札幌コンベンションセンター
- Year and Date
  2016-03-27
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] 鉄欠乏状態は活性酸素シグナルを介して細胞老化を促進する2016
- Author(s)
  井上博文、勝間田(坪井)理恵、高橋信之、上原万里子
- Organizer
  第27回日本微量元素学会学術集会
- Place of Presentation
  京都府京都市　京都大学医学部創立百周年記念施設　芝蘭会館
- Year and Date
  2016-07-30
- Data Source
  KAKENHI-PROJECT-16K16609
[Presentation] Equol鏡像異性体の再吸収動態と骨量減少抑制作用の差異2016
- Author(s)
  藤井俊吾、生城真一、室田佳恵子、太田篤胤、井上博文、高橋信之、上原万里子
- Organizer
  第21回日本フードファクター学会学術集会
- Place of Presentation
  富山国際会議場（富山県・富山市）
- Year and Date
  2016-11-19
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] オレウロペイン代謝産物hydroxytyrosolによる破骨細胞分化抑制メカニズム2016
- Author(s)
  井上博文、勝間田(坪井) 理恵、高橋信之、上原万里子
- Organizer
  第10回日本ポリフェノール学会学術集会
- Place of Presentation
  芝浦工業大学豊洲キャンパス（東京都・江東区）
- Year and Date
  2016-08-04
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Sulforaphaneの続発性骨粗鬆症に対する有効性および作用機序の検討2016
- Author(s)
  髙木智弘、井上博文、高橋信之、牛田悠介、菅沼大行、上原万里子
- Organizer
  第70回日本栄養・食糧学会大会
- Place of Presentation
  神戸ポートピアホテル・武庫川女子大学中央キャンパス（兵庫県・神戸市および西宮市）
- Year and Date
  2016-05-13
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Sulforaphene, sulforaphene and erucin, sulfur containing compounds, inhibit osteoclasts differentiation via down-regulating cell-cell fusion molecules associated to osteoclast differentiation.2015
- Author(s)
  Takagi T, Inoue H, Takahashi N, Uehara M.
- Organizer
  12th Asian Congress of Nutrition (ACN2015)
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Iron deficiency induces autophagy through activation of Nrf2/Keap1 system and phosphorylation of p62 (Thr351) against oxidative stress2015
- Author(s)
  H. Inoue, KI. Kobayashi, T. Suzuki, Y. Yamamoto, SI. Katsumata, R. Katsumata-Tsuboi, N. Takahashi, M Uehara
- Organizer
  第6回国際フードファクター学会
- Place of Presentation
  ソウル市(韓国)
- Year and Date
  2015-11-21
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] A combination of soy isoflavones and cellooligosaccharides improves equol production and bone fragility in ovariectomized mice.2015
- Author(s)
  Fujii S, Inoue H, Takahashi N, Kikkawa Y, Machida M, Uehara M.
- Organizer
  6th International Conference on Food Factors (ICoFF2015)
- Place of Presentation
  Coex, Seoul, Korea
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 鉄欠乏状態における異常タンパク質分解システム活性化機構に関する研究2015
- Author(s)
  井上博文、塙信彰、勝間田真一、坪井理恵、高橋信之、上原万里子
- Organizer
  日本食生活学会第50回記念大会
- Place of Presentation
  東京農業大学
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] Bone-sparing effects of phytochemicals in vitro and in rodent models of osteoporosis.2015
- Author(s)
  Uehara M, Inoue H, Takahashi N.
- Organizer
  12th Asian Congress of Nutrition (ACN2015)
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2015-05-14
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Differences in effects of equol enantiomers in vivo and in vitro.2015
- Author(s)
  Fujii S, Inoue H, Takahashi N, Uehara M.
- Organizer
  12th Asian Congress of Nutrition (ACN2015)
- Place of Presentation
  Pacifico Yokohama, Kanagawa, Japan
- Year and Date
  2015-05-14
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 鉄欠乏状態が活性酸素シグナルとタンパク質品質機構に及ぼす影響2015
- Author(s)
  井上博文、小林謙一、鈴木司、山本祐司、勝間田(坪井) 理恵、勝間田真一、高橋信之、上原万里子
- Organizer
  第96回日本栄養・食糧学会関東支部大会
- Place of Presentation
  新潟大学
- Year and Date
  2015-09-05
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] Isothiocyanates suppressed the osteoclast differentiation by decreasing master regulator of osteoclast fusion factor DC-STAMP.2015
- Author(s)
  Takagi T, Inoue H, Takahashi N, Uehara M.
- Organizer
  6th International Conference on Food Factors (ICoFF2015)
- Place of Presentation
  Coex, Seoul, Korea
- Year and Date
  2015-11-22
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Beyond antioxidative and anti-inflammatory activities of phytochemicals inhibit osteoclastogenesis.2015
- Author(s)
  Uehara M, Inoue H, Takahashi N.
- Organizer
  The International Chemical Congress of Pacific Basin Societies 2015 (Pacifichem 2015)
- Place of Presentation
  Sheraton Waikiki Hotel, Honolulu, Hawaii, USA.
- Year and Date
  2015-12-15
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] Iron deficiency regulates oxidative stress via inducing anti-oxidant enzymes and activating autophagy2015
- Author(s)
  H. Inoue, N. Hanawa, N. Takahashi, M. Uehara
- Organizer
  12th Asian Congress of Nutrition・第69回日本栄養・食糧学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-05-14
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] Comparative activities of isoflavone metabolites on osteoclastogenesis in vitro and bone loss in vivo.2015
- Author(s)
  Uehara M, Inoue H, Takahashi N.
- Organizer
  6th International Conference on Food Factors (ICoFF2015)
- Place of Presentation
  Coex, Seoul, Korea
- Year and Date
  2015-11-22
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H01767
[Presentation] 鉄欠乏状態における異常タンパク質分解システム活性化機構に関する研究2015
- Author(s)
  井上博文、塙信彰、勝間田真一、坪井理恵、高橋信之、上原万里子
- Organizer
  日本食生活学会第50回大会
- Place of Presentation
  東京農業大学
- Year and Date
  2015-05-30
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] 鉄欠乏状態が加齢疾患リスクと活性酸素シグナルに与える影2015
- Author(s)
  井上博文、勝間田(坪井)理恵、高橋信之、上原万里子
- Organizer
  BMB2015(第38回日本分子生物学会年会・第88回日本生化学会大会合同大会)
- Place of Presentation
  神戸ポートアイランド
- Year and Date
  2015-12-01
- Invited
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] Dietary iron deficiency induces expression of metal-ion transporters and anti-oxidant enzymes in mouse heart2013
- Author(s)
  Hirofumi Inoue, Shin-Ichi Katsumata, Ken-Ichi Kobayashi, Yuji Yamamoto, Kazuharu Suzuki, Mariko Uehara
- Organizer
  The 8th Asia Pacific Conference on Clinical Nutrition
- Place of Presentation
  TOKYO BAY, MAIHAMA
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] 鉄欠乏によるオートファジー誘導と生体防御機構
- Author(s)
  井上博文、塙信彰、勝間田真一、高橋信之、上原万里子
- Organizer
  第19回ニホンフードファクター学会学術集会
- Place of Presentation
  鹿児島大学
- Year and Date
  2014-11-08 – 2014-11-09
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] Iron deficiency regulates oxidative stress via inducing anti-oxidant enzymes and activating autophagy.
- Author(s)
  Hirofumi Inoue, Nobuaki Hanawa, Nobuyuki Takahashi, Mariko Uehara
- Organizer
  ACN2015・第69回日本栄養・食糧学会大会
- Place of Presentation
  パシフィコ横浜
- Year and Date
  2015-05-14 – 2015-05-17
- Data Source
  KAKENHI-PROJECT-25750057
[Presentation] 鉄欠乏時では活性酸素シグナルセンサーとオートファジーを活性化することで細胞内恒常性を維持する
- Author(s)
  井上博文、勝間田真一、高橋信之、上原万里子
- Organizer
  2015年度日本農芸化学会
- Place of Presentation
  岡山大学
- Year and Date
  2015-03-26 – 2015-03-29
- Data Source
  KAKENHI-PROJECT-25750057

1. UEHARA Mariko (20211071)

# of Collaborated Projects: 2 results

# of Collaborated Products: 43 results
2. 高橋信之 (50370135)

# of Collaborated Projects: 2 results

# of Collaborated Products: 43 results
3. KATSUMATA Shin-ichi (10424681)

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
4. 石見佳子 (50154159)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 萩原真 (30546099)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 森本洋武 (00965577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 福島穂高 (60645076)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. IKUSHIRO Shin-ichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
9. MUROTA Kaeko

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
10. KATSUMATA Rie

# of Collaborated Projects: 1 results

# of Collaborated Products: 7 results
11. Felix Angelina DR.

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
12. 田中未央里

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

INOUE Hirofumi 井上 博文

Inoue Hirofumi 井上 博文

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Co-Researchers

Importance of Magnesium in Diabetes Mellitus: Toward Establishing Methods of Prevention and Improvement

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妊娠胎生期の鉄欠乏状態が生後の大脳皮質組織異常と脳内炎症に及ぼす影響Principal Investigator

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Controls of inflammation and intestinal environment by intestinal bacterial metabolites for extending healthy life expectancy

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Bone-Specific Epigenetic Changes via Vitamin B 12 Metabolism under Iron Deficiency ConditionsPrincipal Investigator

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Effects of iron deficiency on the vitamin metabolites and age-related diseasesPrincipal Investigator

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Mechanisms of inflammation control in functional phytochemicals: Counterplans against lifestyle-related diseases based on chronic inflammation

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Effects of mineral deficiency diet on between aging-disease and reactive oxygen signalPrincipal Investigator

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[Book] ポリフェノールの科学（Ⅱ. ポリフェノールの健康機能 9. ロコモティブシンドロームの予防 9.1 骨）2023

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[Journal Article] A modified system using macrophage-conditioned medium revealed that the indirect effects of anti-inflammatory food-derived compounds improve inflammation-induced suppression of UCP-1 mRNA expression in 10T1/2 adipocytes2024

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[Journal Article] Prevention of Metabolic Syndrome and Locomotive Syndrome Using Food Factors Targeting Chronic Inflammation2024

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[Journal Article] Mechanism of Lipid Metabolism Abnormalities Resulting in Obesity, Diabetes, and Postprandial Hyperlipidemia2024

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[Journal Article] AMPK negatively regulates RANKL-induced osteoclast differentiation by controlling oxidative stress2023

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[Journal Article] Resveratrol Upregulates Senescence Marker Protein 30 by Activating AMPK/Sirt1-Foxo1 Signals and Attenuating H<sub>2</sub>O<sub>2</sub>-Induced Damage in FAO Rat Liver Cells2023

Author(s)

Journal Title

INOUE Hirofumi 井上博文

Inoue Hirofumi 井上博文

[Book] ポリフェノールの科学（Ⅱ. ポリフェノールの健康機能　9. ロコモティブシンドロームの予防　9.1 骨）2023