Abe Yoshiyuki 安倍能之

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ABE yoshiyuki 安倍能之

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Researcher Number	10647027
Other IDs
Affiliation (Current)	2025: 順天堂大学, 大学院医学研究科, 助教 2025: 順天堂大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2024: 順天堂大学, 大学院医学研究科, 助教 2018 – 2023: 順天堂大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 52010:General internal medicine-related Except Principal Investigator Basic Section 49030:Experimental pathology-related / Collagenous pathology/Allergology
Keywords	Principal Investigator 抗MDA5抗体 / 疾患モデル動物 / モデルマウス作成 / 血清バイオマーカー解析 / 皮膚筋炎 / 間質性肺炎 / 抗体誘導性間質性肺炎モデルマウス / 生存率の改善 / 治療抵抗性 / 新規治療法の開発 / 急速進行性間質性肺炎 / 血漿交換療法 / 動物実験モデル … More Except Principal Investigator … More 喘息 / 免疫学 / 診断薬 / 炎症 / アレルギー / 免疫 / 関節リウマチ / 自己免疫疾患 / アレルギー疾患 / アレルギー・ぜんそく / ぜんそく Less

抗MDA5抗体陽性間質性肺炎の新規動物疾患モデルの樹立とヒト患者検体の比較研究Principal Investigator
- Principal Investigator
  
  安倍能之
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Juntendo University
Functional analysis of TIM molecules that regulate the pathogenesis of autoimmune and allergic diseases
- Principal Investigator
  
  Akiba Hisaya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Juntendo University
Functional and pathophysiology analysis of anti-MDA5 antibodyPrincipal Investigator
- Principal Investigator
  
  Yoshiyuki Abe
- Project Period (FY)
  2018 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 52010:General internal medicine-related
- Research Institution
  Juntendo University
Detection of human TIM-4 on autoimmune and allergic diseases
- Principal Investigator
  
  Akiba Hisaya
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Collagenous pathology/Allergology
- Research Institution
  Juntendo University

All 2024 2023 2022 2021 2020 2019 2018 2017 2016

All Journal Article Presentation Patent

[Journal Article] MAP3K19 Affects TWEAK-Induced Response in Cultured Bronchial Epithelial Cells and Regulates Allergic Airway Inflammation in an Asthma Murine Model2023
- Author(s)
  Sandhu Yuuki、Harada Norihiro、Harada Sonoko、Nishimaki Takayasu、Sasano Hitoshi、Tanabe Yuki、Takeshige Tomohito、Matsuno Kei、Ishimori Ayako、Katsura Yoko、Ito Jun、Akiba Hisaya、Takahashi Kazuhisa
- Journal Title
  
  Current Issues in Molecular Biology
  
  Volume: 45 Issue: 11 Pages: 8907-8924
- DOI
  10.3390/cimb45110559
- Data Source
  KAKENHI-PROJECT-20H03472
[Journal Article] Pretreatment Frequency of Circulating Th17 Cells and FeNO Levels Predicted the Real-World Response after 1 Year of Benralizumab Treatment in Patients with Severe Asthma2023
- Author(s)
  Sandhu Yuuki、Harada Norihiro、Sasano Hitoshi、Harada Sonoko、Ueda Shoko、Takeshige Tomohito、Tanabe Yuki、Ishimori Ayako、Matsuno Kei、Abe Sumiko、Nagaoka Tetsutaro、Ito Jun、Chiba Asako、Akiba Hisaya、Atsuta Ryo、Izuhara Kenji、Miyake Sachiko、Takahashi Kazuhisa
- Journal Title
  
  Biomolecules
  
  Volume: 13 Issue: 3 Pages: 538-538
- DOI
  10.3390/biom13030538
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02964, KAKENHI-PROJECT-20K08549, KAKENHI-PROJECT-20K08807, KAKENHI-PROJECT-23K07658, KAKENHI-PROJECT-21K08476, KAKENHI-PROJECT-20H03472
[Journal Article] Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen2022
- Author(s)
  Ueda Shoko、Ito Jun、Harada Norihiro、Harada Sonoko、Sasano Hitoshi、Sandhu Yuuki、Tanabe Yuki、Abe Sumiko、Shiota Satomi、Kodama Yuzo、Nagaoka Tetsutaro、Makino Fumihiko、Chiba Asako、Akiba Hisaya、Atsuta Ryo、Miyake Sachiko、Takahashi Kazuhisa
- Journal Title
  
  Biomolecules
  
  Volume: 12 Issue: 4 Pages: 518-518
- DOI
  10.3390/biom12040518
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K08549, KAKENHI-PROJECT-20H03472
[Journal Article] Successful treatment of anti-MDA5 antibody-positive refractory interstitial lung disease with plasma exchange therapy2020
- Author(s)
  Abe Yoshiyuki、Kusaoi Makio、Tada Kurisu、Yamaji Ken、Tamura Naoto
- Journal Title
  
  Rheumatology
  
  Volume: 59 Issue: 4 Pages: 767-771
- DOI
  10.1093/rheumatology/kez357
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K15433
[Journal Article] Protective role of ICOS and ICOS Ligand in corneal transplantation and in maintenance of immune privilege2016
- Author(s)
  Kunishige T, Taniguchi H, Terada M, Akiba H, Yagita H, Abe R, Hori J
- Journal Title
  
  Invest Ophthalmol Vis Sci
  
  Volume: 57(15) Issue: 15 Pages: 6815-6823
- DOI
  10.1167/iovs.16-20644
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-26462700, KAKENHI-PROJECT-15K20290, KAKENHI-PROJECT-16K09924
[Patent] 間質性肺炎モデル非ヒト動物の作製方法2019
- Inventor(s)
  安倍能之、田村直人
- Industrial Property Rights Holder
  順天堂大学
- Industrial Property Rights Type
  特許
- Patent Publication Number
  2021-100388
- Filing Date
  2019
- Acquisition Date
  2021
- Data Source
  KAKENHI-PROJECT-18K15433
[Patent] 抗MDA5抗体誘導性間質性肺炎モデルマウス2019
- Inventor(s)
  安倍能之、田村直人
- Industrial Property Rights Holder
  安倍能之、田村直人
- Industrial Property Rights Type
  特許
- Filing Date
  2019
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] Analysis of clinical utility of soluble TIM-4 in rheumatoid arthritis patient serum2024
- Author(s)
  Hisaya Akiba, Yoshiyuki Abe, Yoko Tabe, Naoto Tamura, Sachiko Miyake
- Organizer
  第52回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-20H03472
[Presentation] Circulating MAIT cells, neutrophils, and periostin as biomarkers for mepolizumab in asthmatics2023
- Author(s)
  Hitoshi Sasano, Norihiro Harada, Sonoko Harada, Tomohito Takeshige, Yuuki Sandhu, Yuki Tanabe, Ayako Ishimori, Kei Matsuno, Tetsutaro Nagaoka, Jun Ito, Asako Chiba, Hisaya Akiba, Ryo Atsuta, Kenji Izuhara, Sachiko Miyake, and Kazuhisa Takahashi
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H03472
[Presentation] Role of MAP3K19 in Allergic Airway Inflammation of Asthma2023
- Author(s)
  Yuuki Sandhu, Norihiro Harada, Sonoko Harada, Hitoshi Sasano, Simiko Abe, Shoko Ueda, Takayasu Nishimaki, Yoshihiko Sato, Takayasu Watanabe, Tomohito Takeshige, Kei Matsuno, Jun Ito, Hisaya Akiba, Kazuhisa Takahashi
- Organizer
  第63回日本呼吸器学会学術講演会
- Data Source
  KAKENHI-PROJECT-20H03472
[Presentation] Soluble TIM-4 levels in serum are associated with severe asthma phenotype.2022
- Author(s)
  Yuki Tanabe, Hisaya Akiba, Norihiro Harada, and Sachiko Miyake.
- Organizer
  第51回日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-20H03472
[Presentation] Extended report: Successful treatment anti-MDA5 antibody-positive interstitial lung disease with plasma exchange therapy2021
- Author(s)
  Yoshiyuki Abe, Masahiro Kogami, Makio Kusaoi, Kurisu Tada, Ken Yamaji, Naoto Tamura
- Organizer
  第22回アジア太平洋リウマチ学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] Extended report: Successful treatment anti-MDA5 antibody-positive interstitial lung disease with plasma exchange therapy2021
- Author(s)
  Yoshiyuki Abe, Masahiro Kogami, Makio Kusaoi, Kurisu Tada, Ken Yamaji, Naoto Tamura
- Organizer
  欧州リウマチ学会2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] 重症ないし治療抵抗性抗MDA5抗体陽性急速進行性間質性肺炎に対する単純血漿交換療法の有効性2021
- Author(s)
  安倍　能之、小神昌寛、草生真規雄多田久里守、山路健、田村直人
- Organizer
  第66回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] Soluble TIM-4 levels in serum are associated with severe asthma phenotype.2021
- Author(s)
  Y. Tanabe, H. Akiba, N. Harada, K. Matsuno, J. Ito, S. Miyake, K. Takahashi
- Organizer
  The 25th Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20H03472
[Presentation] 急速進行性間質性肺疾患を呈した抗MDA5抗体陽性皮膚筋炎患者IgGの病原性とモデルマウス作成2021
- Author(s)
  小神　昌寛，安倍　能之，山路　健，田村　直人
- Organizer
  第65回日本リウマチ学会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] 治療抵抗性を示す抗MDA5抗体陽性皮膚筋炎関連急速進行性間質性肺炎に対する単純血漿交換療法の有効性2020
- Author(s)
  安倍能之、草生真規雄、多田久里守、山路健、田村直人
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] The effectiveness of plasma exchange therapy for anti-MDA5 antibody-positive refractory interstitial lung disease2020
- Author(s)
  Yoshiyuki Abe, Taiga Kuga, Makio Kusaoi, Kurisu Tada, Ken Yamaji, Naoto Tamura
- Organizer
  22nd Asia-Pacific League of Associations for Rheumatology 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] The effectiveness of plasma exchange therapy for anti-MDA5 antibody-positive refractory interstitial lung disease2020
- Author(s)
  Yoshiyuki Abe, Taiga Kuga, Makio Kusaoi, Kurisu Tada, Ken Yamaji, Naoto Tamura
- Organizer
  European congress of rheumatology 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] 急速進行性間質性肺疾患を呈した抗MDA5抗体陽性皮膚筋炎患者IgGの病原性とモデルマウス作製2020
- Author(s)
  小神昌寛、安倍能之、山路健、田村直人
- Organizer
  第65回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] The effectiveness of plasma exchange therapy for anti-MDA5 antibody-positive refractory interstitial lung disease2019
- Author(s)
  Yoshiyuki Abe, Taiga Kuga, Makio Kusaoi, Kurisu Tada, Ken Yamaji, Naoto Tamura
- Organizer
  European congress of rheumatology 2020
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] 治療抵抗性を示す抗MDA5抗体陽性皮膚筋炎関連急速進行性間質性肺炎に対する単純血漿交換療法の有効性2019
- Author(s)
  安倍能之、草生真規雄、多田久里守、山路健、田村直人
- Organizer
  第64回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] Circulating levels of soluble TIM-4 in the patients with asthma2018
- Author(s)
  Yuki Tanabe, Hisaya Akiba, Norihiro Harada, Kei Matsuno, Jun Ito, Kazuhisa Takahashi, and Sachiko Miyake
- Organizer
  第47回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09924
[Presentation] Chitin Induced Airway Inflammation and Production of Prostaglandin E22018
- Author(s)
  T. Takeshige, N. Harada, K. Matsuno, A. Ishimori, Y. Tanabe, H. Sasano, A. Nakamura, S. Harada, Y. Katsura, F. Makino, J. Ito, R. Atsuta, H. Akiba, K. Takahashi
- Organizer
  第58回日本呼吸器学会会学術講演会
- Data Source
  KAKENHI-PROJECT-16K09924
[Presentation] 抗MDA5抗体陽性皮膚筋炎の急速進行性間質性肺炎治療中にニューモシスチス肺炎を発症し、単純血漿交換療法での治療が奏功した一例2018
- Author(s)
  小神　昌寛、安倍能之、多田久里守、山路健、田村直人
- Organizer
  第63回日本リウマチ学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-18K15433
[Presentation] TWEAK enhances epithelial mesenchymal transition and chemokine production in human bronchial epithelial cells2017
- Author(s)
  Kei Matsuno, Norihiro Harada, Itoigawa Yukinari, Tomohito Takeshige, Sonoko Harada, Ayako Ishimori, Yuki Tanabe, Yoko Katsura, Fumihiko Makino, Jun Ito, Ryo Atsuta, Hisaya Akiba, Kazuhisa Takahashi
- Organizer
  第46回日本免疫学会学術集会
- Data Source
  KAKENHI-PROJECT-16K09924
[Presentation] TWEAK and TGF-β induced chemokine production in human bronchial epithelial cells during epithelial mesenchymal transition2017
- Author(s)
  Kei Matsuno, Norihiro Harada, Tomohito Takeshige, Ayako Ishimori, Yuki Tanabe, Hitoshi Sasano, Ai Nakamura, Yoko Katsura, Fumihiko Makino, Jun Ito, Ryo Atsuta, Hisaya Akiba, Kazuhisa Takahashi
- Organizer
  The 22nd Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09924
[Presentation] Chitin induced airway inflammation and production of prostaglandin E22017
- Author(s)
  Tomohito Takeshige, Norihiro Harada, Kei Matsuno, Ayako Ishimori, Yuki Tanabe, Hitoshi Sasano, Ai Nakamura, Sonoko Harada, Yoko Katsura, Fumihiko Makino, Jun Ito, Ryo Atsuta, Hisaya Akiba, Kazuhisa Takahashi
- Organizer
  The 22nd Congress of the Asian Pacific Society of Respirology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09924

1. Akiba Hisaya (60338316)

# of Collaborated Projects: 2 results

# of Collaborated Products: 12 results
2. HARADA norihiro (10465065)

# of Collaborated Projects: 2 results

# of Collaborated Products: 11 results
3. 多田昇弘 (50338315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 牧山彩子 (40876687)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 小神昌寛 (90985756)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. CHIBA Asako

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 三宅幸子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 安部良

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 堀純子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 八木田秀雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 谷口ヒロ子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 國重智之

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Abe Yoshiyuki 安倍 能之

ABE yoshiyuki 安倍 能之

Research Projects

Research Products

Co-Researchers

抗MDA5抗体陽性間質性肺炎の新規動物疾患モデルの樹立とヒト患者検体の比較研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of TIM molecules that regulate the pathogenesis of autoimmune and allergic diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional and pathophysiology analysis of anti-MDA5 antibodyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Detection of human TIM-4 on autoimmune and allergic diseases

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] MAP3K19 Affects TWEAK-Induced Response in Cultured Bronchial Epithelial Cells and Regulates Allergic Airway Inflammation in an Asthma Murine Model2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Pretreatment Frequency of Circulating Th17 Cells and FeNO Levels Predicted the Real-World Response after 1 Year of Benralizumab Treatment in Patients with Severe Asthma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of Japanese Cedar Pollen Sublingual Immunotherapy on Asthma Patients with Seasonal Allergic Rhinitis Caused by Japanese Cedar Pollen2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Successful treatment of anti-MDA5 antibody-positive refractory interstitial lung disease with plasma exchange therapy2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Protective role of ICOS and ICOS Ligand in corneal transplantation and in maintenance of immune privilege2016

Author(s)

Journal Title

DOI

Data Source

[Patent] 間質性肺炎モデル非ヒト動物の作製方法2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Patent Publication Number

Filing Date

Acquisition Date

Data Source

[Patent] 抗MDA5抗体誘導性間質性肺炎モデルマウス2019

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Filing Date

Data Source

[Presentation] Analysis of clinical utility of soluble TIM-4 in rheumatoid arthritis patient serum2024

Author(s)

Organizer

Data Source

[Presentation] Circulating MAIT cells, neutrophils, and periostin as biomarkers for mepolizumab in asthmatics2023

Author(s)

Organizer

Data Source

[Presentation] Role of MAP3K19 in Allergic Airway Inflammation of Asthma2023

Author(s)

Organizer

Data Source

Abe Yoshiyuki 安倍能之

ABE yoshiyuki 安倍能之

[Presentation] 治療抵抗性を示す抗MDA5抗体陽性皮膚筋炎関連急速進行性間質性肺炎に対する単純血漿交換療法の有効性2020

[Presentation] 治療抵抗性を示す抗MDA5抗体陽性皮膚筋炎関連急速進行性間質性肺炎に対する単純血漿交換療法の有効性2019