TAKEISHI Shoichiro 武石昭一郎

Researcher Number	10647720
Other IDs
Affiliation (based on the past Project Information) *help	2013 – 2015: 九州大学, 生体防御医学研究所, 研究員 2014: 九州大学, 生体防御医学研究所, 特任助教
Review Section/Research Field	Principal Investigator General physiology / Tumor biology
Keywords	Principal Investigator 細胞周期 / 静止期 / がん幹細胞 / CDKインヒビター / p57 / タンパク質分解 / ユビキチン / Fbxw7 / 乳がん / 白血病幹細胞 … More / 造血幹細胞 / 間葉系幹細胞 / 腸管幹細胞 / +4幹細胞 / CBC幹細胞 / Bmi1 / Lgr5 / 体性幹細胞 Less

間葉系幹細胞の静止期維持機構の打破によるがん幹細胞の根絶Principal Investigator
- Principal Investigator
  
  武石昭一郎
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Young Scientists (A)
- Research Field
  
  General physiology
- Research Institution
  Kyushu University
Purification of intestinal stem cells on the basis of their cell cycle status and its application to regenerative medicinePrincipal Investigator
- Principal Investigator
  
  Takeishi Shoichiro
- Project Period (FY)
  2015
- Research Category
  
  Grant-in-Aid for Challenging Exploratory Research
- Research Field
  
  General physiology
- Research Institution
  Kyushu University
Elucidation of the mechanism of maintenance of quiescence in cancer stem cellsPrincipal Investigator
- Principal Investigator
  
  TAKEISHI Shoichiro
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Tumor biology
- Research Institution
  Kyushu University

All 2016 2015 2014 2013 Other

All Journal Article Presentation Book

[Book] 日本臨牀2015
- Author(s)
  武石　昭一郎
- Total Pages
  5
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-15H05645
[Book] 細胞工学2015
- Author(s)
  武石　昭一郎
- Total Pages
  1
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 日本臨牀2015
- Author(s)
  武石昭一郎
- Total Pages
  5
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-15K15032
[Book] 細胞工学2015
- Author(s)
  武石昭一郎
- Total Pages
  1
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-15K15032
[Book] 細胞工学2015
- Author(s)
  武石　昭一郎
- Total Pages
  1
- Publisher
  秀潤社
- Data Source
  KAKENHI-PROJECT-15H05645
[Book] 日本臨牀2015
- Author(s)
  武石　昭一郎
- Total Pages
  5
- Publisher
  日本臨牀社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] Surgery Frontier2014
- Author(s)
  武石　昭一郎
- Total Pages
  3
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 血液内科2014
- Author(s)
  武石　昭一郎
- Total Pages
  7
- Publisher
  科学評論社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] Surgery Frontier2014
- Author(s)
  武石　昭一郎、中山　敬一
- Total Pages
  3
- Publisher
  メディカルレビュー社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 直伝！フローサイトメトリー　面白いほど使いこなせる！2014
- Author(s)
  武石　昭一郎、中山　敬一
- Total Pages
  12
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 臨床血液2014
- Author(s)
  武石　昭一郎
- Total Pages
  1
- Publisher
  日本血液学会
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 次世代がん戦略研究Update2013
- Author(s)
  武石　昭一郎、中山　敬一
- Total Pages
  4
- Publisher
  南山堂
- Data Source
  KAKENHI-PROJECT-25830084
[Book] 実験医学2013
- Author(s)
  武石　昭一郎、中山　敬一
- Total Pages
  4
- Publisher
  羊土社
- Data Source
  KAKENHI-PROJECT-25830084
[Journal Article] To wake up cancer stem cells, or to let them sleep, that is the question2016
- Author(s)
  Shoichiro Takeishi and Keiichi I. Nakayama
- Journal Title
  
  Cancer Science
  
  Volume: 107
- DOI
  10.1111/cas.12958
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-15K15032
[Journal Article] Role of Fbxw7 in the maintenance of normal stem cells and cancer-initiating cells2014
- Author(s)
  Shoichiro Takeishi, Keiichi I. Nakayama
- Journal Title
  
  Br. J. Cancer
  
  Volume: 111 Pages: 1054-1059
- DOI
  10.1038/bjc.2014.259
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Journal Article] p57 regulates T-cell development and prevents lymphomagenesis by balancing p53 activity and pre-TCR signaling2014
- Author(s)
  Matsumoto, A., Takeishi, S., Nakayama, K. I.
- Journal Title
  
  Blood
  
  Volume: 123 Pages: 1-11
- DOI
  10.1182/blood-2013-10-532390
- Peer Reviewed
- Data Source
  KAKENHI-ORGANIZER-22130001, KAKENHI-PLANNED-22130003, KAKENHI-PROJECT-25830084, KAKENHI-PROJECT-25221303
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction to leukemia stem cells through altered microenvironmental regulation2016
- Author(s)
  Shoichiro Takeishi
- Organizer
  JMSA New York Life Science Forum 2016
- Place of Presentation
  New York
- Year and Date
  2016-04-09
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] p57はp53の活性化とpre-TCRシグナルのバランスを取ることによりT細胞の分化を制御し、悪性リンパ腫の発症を抑制する2015
- Author(s)
  武石　昭一郎、松本　有樹修、中山　敬一
- Organizer
  第11回麒麟塾
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] p57 is required for the maintenance of quiescence in intestinal stem cells2015
- Author(s)
  Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shoichiro Takeishi and Keiichi I. Nakayama
- Organizer
  The 18th Medical Institute of Bioregulation Retreat
- Place of Presentation
  Kumamoto
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] p57 maintains epithelial homeostasis via regulation of quiescent intestinal stem cells2015
- Author(s)
  Tsunaki Higa, Yasutaka Okita, Akinobu Matsumoto, Shoichiro Takeishi and Keiichi I. Nakayama
- Organizer
  The 25th Hot Spring Harbor International Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2015-11-13
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction to leukemia stem cells through altered microenvironmental regulation2015
- Author(s)
  Shoichiro Takeishi, Akinobu Matsumoto, Kazuhito Naka, Atsushi Hirao and Keiichi I. Nakayama
- Organizer
  The 18th Medical Institute of Bioregulation Retreat
- Place of Presentation
  Kumamoto
- Year and Date
  2015-07-16
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] p57はp53の活性化とpre-TCRシグナルのバランスを取ることによりT細胞の分化を制御し、悪性リンパ腫の発症を抑制する2015
- Author(s)
  武石　昭一郎
- Organizer
  第11回麒麟塾
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-15H05645
[Presentation] p57は静止状態の腸管幹細胞を制御することで腸管上皮の恒常性を維持する2015
- Author(s)
  比嘉綱己、沖田康孝、松本有樹修、武石昭一郎、中山敬一
- Organizer
  第38回日本分子生物学会年会
- Place of Presentation
  神戸
- Year and Date
  2015-12-01
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] p57はp53の活性化とpre-TCRシグナルのバランスを取ることによりT細胞の分化を制御し、悪性リンパ腫の発症を抑制する2015
- Author(s)
  武石昭一郎
- Organizer
  第11回麒麟塾
- Place of Presentation
  東京
- Year and Date
  2015-07-11
- Invited
- Data Source
  KAKENHI-PROJECT-15K15032
[Presentation] Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence2014
- Author(s)
  武石　昭一郎
- Organizer
  がん支援　冬期公開シンポジウム
- Place of Presentation
  東京
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Fbxw7 prevents the G0-G1 transition to maintain quiescence in cancer stem cells2014
- Author(s)
  Shoichiro Takeishi
- Organizer
  Cold Spring Harbor Laboratory Meeting (The Cell Cycle)
- Place of Presentation
  New York
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction on leukemia stem cells through altered microenvironmental regulation2014
- Author(s)
  Shoichiro Takeishi
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Fbxw7による白血病幹細胞の静止期維持機構の解明と治療応用2013
- Author(s)
  武石　昭一郎
- Organizer
  第19回血液科学セミナー
- Place of Presentation
  東京
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Fbxw7による白血病幹細胞の静止期維持機構の解明と治療応用2013
- Author(s)
  武石　昭一郎
- Organizer
  第1回ブリストル血液学アカデミー
- Place of Presentation
  福岡
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence2013
- Author(s)
  武石　昭一郎
- Organizer
  第36回分子生物学会年会
- Place of Presentation
  神戸
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] がん幹細胞の静止期維持機構の解明とがん治療への応用2013
- Author(s)
  武石　昭一郎
- Organizer
  第72回日本癌学会学術総会
- Place of Presentation
  横浜
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence2013
- Author(s)
  Shoichiro Takeishi
- Organizer
  The 3rd France-Japan Cancer Workshop
- Place of Presentation
  Toulouse
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction to leukemia stem cells through altered niche regulation
- Author(s)
  Shoichiro Takeishi, Akinobu Matsumoto, Keiichi Nakayama
- Organizer
  The 24th Hot Spring Harbor International Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2014-11-07 – 2014-11-08
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] p57を欠損させた白血病幹細胞はニッチ制御の変化によりがん遺伝子依存性となる
- Author(s)
  武石　昭一郎、松本　有樹修、仲　一仁、平尾　敦、中山　敬一
- Organizer
  第37回日本分子生物学会年会
- Place of Presentation
  横浜
- Year and Date
  2014-11-25 – 2014-11-27
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] がん治療の真の標的「がん幹細胞」の静止期維持機構とその打破
- Author(s)
  武石　昭一郎
- Organizer
  平成26年度京都大学原子炉実験所専門研究会
- Place of Presentation
  大阪
- Year and Date
  2014-08-09 – 2014-08-10
- Invited
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Fbxw7 prevents the G0-G1 transition to maitain quiescence in cancer stem cells
- Author(s)
  Shoichiro Takeishi, Akinobu Matsumoto, Ichiro Onoyama, Keiichi Nakayama
- Organizer
  Cold Spring Harbor Laboratory Meeting
- Place of Presentation
  New York
- Year and Date
  2014-05-13 – 2014-05-17
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Ablation of p57 confers oncogene addiction on CML stem cells through altered niche regulation
- Author(s)
  Shoichiro Takeishi, Akinobu Matsumoto, Kazuhito Naka, Atsushi Hirao, Keiichi Nakayama
- Organizer
  The 76th Annual Meeting of the Japanese Society of Hematology (Plenary Session)
- Place of Presentation
  Osaka
- Year and Date
  2014-10-31 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-25830084
[Presentation] Disruption of quiescence by p57 ablation confers oncogene addiction on leukemia stem cells through altered microenvionmental regulation
- Author(s)
  Shoichiro Takeishi, Akinobu Matsumoto, Keiichi Nakayama
- Organizer
  The 12th Stem Cell Research Symposium
- Place of Presentation
  Fukuoka
- Year and Date
  2014-05-30 – 2014-05-31
- Data Source
  KAKENHI-PROJECT-25830084

1. 中山啓子

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
2. 中山敬一

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

TAKEISHI Shoichiro 武石 昭一郎

Research Projects

Research Products

Co-Researchers

間葉系幹細胞の静止期維持機構の打破によるがん幹細胞の根絶Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

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Research Institution

Purification of intestinal stem cells on the basis of their cell cycle status and its application to regenerative medicinePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the mechanism of maintenance of quiescence in cancer stem cellsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 日本臨牀2015

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[Book] 細胞工学2015

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[Book] 日本臨牀2015

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[Book] 細胞工学2015

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[Book] 細胞工学2015

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[Book] 日本臨牀2015

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[Book] Surgery Frontier2014

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[Book] 血液内科2014

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[Book] Surgery Frontier2014

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[Book] 直伝！フローサイトメトリー 面白いほど使いこなせる！2014

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[Book] 臨床血液2014

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[Book] 次世代がん戦略研究Update2013

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TAKEISHI Shoichiro 武石昭一郎

[Book] 直伝！フローサイトメトリー　面白いほど使いこなせる！2014