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sasaki fumiyuki  佐々木 文之

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佐々木 文之  ササキ フミユキ

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Researcher Number 10706469
Other IDs
Affiliation (Current) 2025: 日本医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help 2022 – 2023: 日本医科大学, 医学部, 助教
2019 – 2020: 東京医科歯科大学, 大学院医歯学総合研究科, プロジェクト研究員
Review Section/Research Field
Principal Investigator
Basic Section 59020:Sports sciences-related / Basic Section 56020:Orthopedics-related
Except Principal Investigator
Basic Section 49070:Immunology-related
Keywords
Principal Investigator
イオンチャネル / メカノバイオロジー / 免疫応答 / マイオカイン / メカノセンサー / 炎症 / IL-6 / 骨格筋 / Piezo1 / スクレロスチン / 骨細胞 … More
Except Principal Investigator
… More 自然免疫 / 炎症 / マクロファージ / NLRP3 / インフラマソーム / エンドサイトーシス / クラスリン Less
  • Research Projects

    (3 results)
  • Research Products

    (11 results)
  • Co-Researchers

    (2 People)
  •  Elucidating of molecular mechanism by which endocytosis regulates NLRP3 inflammasome formation and its phycological significance

    • Principal Investigator
      森田 林平
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 49070:Immunology-related
    • Research Institution
      Nippon Medical School
  •  炎症・免疫応答を司る骨格筋特異的メカニカルストレス受容体の新規同定と機能解析Principal Investigator

    • Principal Investigator
      佐々木 文之
    • Project Period (FY)
      2022 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59020:Sports sciences-related
    • Research Institution
      Nippon Medical School
  •  新規スクリーニング法を用いた骨細胞特異的なメカニカルストレス受容体の同定Principal Investigator

    • Principal Investigator
      佐々木 文之
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 56020:Orthopedics-related
    • Research Institution
      Tokyo Medical and Dental University

All 2024 2023 2022 2020 2019

All Journal Article Presentation

  • [Journal Article] Mechanotransduction via the Piezo1-Akt Pathway Underlies Sost Suppression in Osteocytes2020

    • Author(s)
      Sasaki F, Hayashi M, Mouri Y, Nakamura S, Adachi T, Nakashima T.
    • Journal Title

      Biochem Biophys Res Commun.

      Volume: 521 Issue: 3 Pages: 806-813

    • DOI

      10.1016/j.bbrc.2019.10.174

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K18452
  • [Journal Article] The regulation of RANKL by mechanical force2020

    • Author(s)
      Sasaki Fumiyuki、Hayashi Mikihito、Ono Takehito、Nakashima Tomoki
    • Journal Title

      Journal of Bone and Mineral Metabolism

      Volume: 39 Issue: 1 Pages: 34-44

    • DOI

      10.1007/s00774-020-01145-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K17014, KAKENHI-PROJECT-19K18452
  • [Presentation] Sphingosine-1-phosphate lyase SGPL1 is required for NLRP3 inflammasome activation via the dynamic organization of endoplasmic reticulum and microtubules.2024

    • Author(s)
      Fumiyuki Sasaki, Masumi Shimizu, Rimpei Morita
    • Organizer
      第52回日本免疫学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] Gelsolin negatively regulates NLRP3 inflammasome activation by stabilizing mitochondria.2024

    • Author(s)
      Rimpei Morita, Jiyeon Lee, Masumi Shimizu, Fumiyuki Sasaki, Akihiko Yoshimura, Lark Kyun Kim
    • Organizer
      第52回日本免疫学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] Gelsolin from macrophages is required for fibroblast migration during skin wound healing2024

    • Author(s)
      Eri Toyohara, Fumiyuki Sasaki, Teruyuki Dohi, Rei Ogawa, Rimpei Morita
    • Organizer
      第52回日本免疫学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] Clathrin heavy chain regulates NLRP3 inflammasome formation via endocytosis in macrophages.2024

    • Author(s)
      Hung Hiep Huynh, Fumiyuki Sasaki, Masumi Shimizu, Akihiko Yoshimura, Rimpei Morita
    • Organizer
      第52回日本免疫学会学術集会(千葉)
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] The gelsolin-actin axis orchestrates NLRP3 inflammasome activation.2023

    • Author(s)
      Rimpei Morita, Jiyeon Lee, Mika Sunakawa, Eri Koike, Masumi Shimizu, Mariko Ishibashi, Fumiyuki Sasaki, Akihiko Yoshimura, Lark Kyun Kim
    • Organizer
      Keystone Symposia. Innate Immunity: From Innate Sensing to Adaptive Responses (D2)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] Sphingosine-1-phosphate lyase promotes NLRP3 inflammasome activation via the development of endoplasmic reticulum and microtubules.2023

    • Author(s)
      Fumiyuki Sasaki, Masumi Shimizu, Rimpei Morita
    • Organizer
      Keystone Symposia. Innate Immunity: From Innate Sensing to Adaptive Responses (D2)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] phingosine-1-phosphate lyase promotes inflammasome activation via the development of endoplasmic reticulum network2022

    • Author(s)
      Fumiyuki Sasaki, Masumi Shimizu and Rimpei Morita
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] Gelsolin-actin axis organizes NLRP3 inflammasome activation2022

    • Author(s)
      Masumi SHIMIZU, Eri KOIKE, Jiyeon LEE, Fumiyuki SASAKI, Akihiko YOSHIMURA, Lark Kyun KIM, Rimpei MORITA
    • Organizer
      第51回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-22K07140
  • [Presentation] 骨メカニカルストレス受容機構の解明を目指して2019

    • Author(s)
      佐々木 文之、林 幹人、中島 友紀
    • Organizer
      第5回日本骨免疫学会
    • Data Source
      KAKENHI-PROJECT-19K18452
  • 1.  森田 林平 (00362541)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 8 results
  • 2.  小野 岳人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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