ZHANG YING 張影

… Alternative Names

ZHANG Ying 張影

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Researcher Number	10711260
Other IDs
Affiliation (Current)	2023: 山口大学, 医学部, 特別医学研究員
Affiliation (based on the past Project Information) *help	2018 – 2021: 山口大学, 大学院医学系研究科, 講師 2017: 山口大学, 大学院医学系研究科, 助教 2013 – 2016: 山口大学, 医学(系)研究科(研究院), 助教 2014 – 2015: 山口大学, 大学院医学系研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 48020:Physiology-related / General physiology Except Principal Investigator General physiology / Basic Section 48020:Physiology-related / Food science
Keywords	Principal Investigator 血管攣縮 / paxillin / 血管病 / 血管平滑筋 / SPC / tyrosine phosphorylation / abnormal contraction / チロシンリン酸化 / paxillin ノックアウトマウス / paxillin KO mouse … More / 血管平滑筋収縮 / 血管異常収縮 / Ｆｙｎ / 分子間相互作用 / 異常収縮 / Rho-kinase / Fyn / 病的シグナル伝達 … More Except Principal Investigator 血管平滑筋 / 血管異常収縮 / カルパイン / 異常収縮 / ビメンチン / 生理学 / 機能プロテオミクス / 細胞骨格 / 腫瘍細胞浸潤・転移 / 病的シグナル伝達系 / 細胞運動・遊走 / 細胞骨格関連分子 / 食品機能 / 膜ラフト / 機能性食品 / 血管病 / 血管攣縮 / 病態生理 Less

Elucidation of the mechanism by which paxillin controls vascular abnormal contractionPrincipal Investigator
- Principal Investigator
  
  張影
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
中間径フィラメントビメンチンを介した新規血管平滑筋異常収縮シグナル伝達機構の解明
- Principal Investigator
  
  岸博子
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the mechanism by which paxillin controls vascular abnormal contractionPrincipal Investigator
- Principal Investigator
  
  Zhang Ying
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 48020:Physiology-related
- Research Institution
  Yamaguchi University
Elucidation of the involvement of calpain and cytoskeletal proteins in the signal transduction of abnormal vascular smooth muscle contraction
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Searching for the novel signalling molecule in vascular abnormal contractionPrincipal Investigator
- Principal Investigator
  
  ZHANG Ying
- Project Period (FY)
  2015 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Elucidation of the shared signaling pathways for intractable diseases in terms of cytoskeletal rearrangements
- Principal Investigator
  
  KISHI Hiroko
- Project Period (FY)
  2013 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Research for novel signaling molecule involving vascular smooth muscle abnormal contractionPrincipal Investigator
- Principal Investigator
  
  ZHANG Ying
- Project Period (FY)
  2013 – 2014
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  General physiology
- Research Institution
  Yamaguchi University
Identification of food component which selectively inhibits abnormal vascular contraction
- Principal Investigator
  
  KOBAYASHI Sei
- Project Period (FY)
  2011 – 2014
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Research Field
  
  Food science
- Research Institution
  Yamaguchi University

All 2022 2021 2020 2019 2018 2017 2016 2015 2014 2013 2012 Other

All Journal Article Presentation Book Patent

[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm, Muscle Contraction and Cell Motility: Fundamentals and Developments, edited by Haruo Sugi2016
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Total Pages
  454
- Publisher
  Pan Stanford
- Data Source
  KAKENHI-PROJECT-16K08496
[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm. Muscle Contraction and Cell Motility: Fundamentals and Developments edited by Haruo Sugi.2016
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Total Pages
  454
- Publisher
  Pan Stanford Publishing
- Data Source
  KAKENHI-PROJECT-15K18970
[Journal Article] Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway2022
- Author(s)
  Zhang Ying、Lu Qian、Li Nan、Xu Ming、Miyamoto Tatsuo、Liu Jing
- Journal Title
  
  npj Breast Cancer
  
  Volume: 8 Issue: 1 Pages: 40-40
- DOI
  10.1038/s41523-022-00402-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H02718, KAKENHI-PROJECT-21K06782, KAKENHI-PROJECT-21K08756, KAKENHI-PROJECT-20K21845
[Journal Article] Hesperetin Inhibits Sphingosylphosphorylcholine-Induced Vascular Smooth Muscle Contraction by Regulating the Fyn/Rho-Kinase Pathway2022
- Author(s)
  Lu Qian、Kishi Hiroko、Zhang Ying、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  Journal of Cardiovascular Pharmacology
  
  Volume: 79 Issue: 4 Pages: 456-466
- DOI
  10.1097/fjc.0000000000001210
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn2021
- Author(s)
  Zhang Ying、Kishi Hiroko、Morita Tomoka、Kobayashi Sei
- Journal Title
  
  The FASEB Journal
  
  Volume: 35 Issue: 12
- DOI
  10.1096/fj.202101035rr
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-21K06782
[Journal Article] Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn2020
- Author(s)
  Kurahara Lin Hai、Hiraishi Keizo、Yamamura Aya、Zhang Ying、Abe Kohtaro、Yahiro Eiji、Aoki Mikiko、Koga Kaori、Yokomise Hiroyasu、Go Tetsuhiko、Ishikawa Kaori、Bo Zhang、Kishi Hiroko、Kobayashi Sei、Aoki-Shoi Narumi、Toru Satoh、Inoue Ryuji、Hirano Katsuya
- Journal Title
  
  Journal of Molecular and Cellular Cardiology
  
  Volume: 148 Pages: 50-62
- DOI
  10.1016/j.yjmcc.2020.08.013
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07309, KAKENHI-PROJECT-20K07061, KAKENHI-PROJECT-20K07092, KAKENHI-PROJECT-20K07261, KAKENHI-PROJECT-20K07269, KAKENHI-PROJECT-17KK0179, KAKENHI-PROJECT-18K06875
[Journal Article] Add-on therapy with traditional Chinese medicine: An efficacious approach for lipid metabolism disorders2018
- Author(s)
  Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Journal Title
  
  Pharmacological Research
  
  Volume: 134 Pages: 200-211
- DOI
  10.1016/j.phrs.2018.06.004
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K06875, KAKENHI-PROJECT-16K08496
[Journal Article] 血管攣縮の分子機構の解明とその分子標的治療法の開発2018
- Author(s)
  張　影、小林　誠
- Journal Title
  
  Precision Medicine
  
  Volume: １ Pages: 71-77
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K06875
[Journal Article] Omega-3 and omega-6 DPA equally inhibit the sphingosylphosphorylcholine-induced Ca2+-sensitization of vascular smooth muscle contraction via inhibiting Rho-kinase activation and translocation.2017
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi and Sei Kobayashi
- Journal Title
  
  Scientific Report
  
  Volume: 7 Issue: 1 Pages: 1-14
- DOI
  10.1038/srep36368
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-16K08496, KAKENHI-PROJECT-15K18970
[Journal Article] 質量分析計による蛋白質同定～シグナル伝達研究への応用～2015
- Author(s)
  岸博子、張影、小林誠
- Journal Title
  
  山口医学
  
  Volume: 64 Pages: 77-181
- NAID
  130005239550
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K18970
[Journal Article] 質量分析計による蛋白質同定～シグナル伝達研究への応用～2015
- Author(s)
  岸博子、張影、小林誠
- Journal Title
  
  山口医学
  
  Volume: 64 Pages: 77-181
- NAID
  130005239550
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25460290
[Journal Article] 食品成分による血管病予防の新展開2012
- Author(s)
  加治屋勝子、岸博子、高田雄一、張影、木村友彦、宮成健司、萩原弘、小林誠
- Journal Title
  
  FFIジャーナル
  
  Volume: 217 Pages: 284-289
- NAID
  40019419438
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23380077
[Patent] SPC/Fyn/Rhoキナーゼシグナル伝達経路の阻害剤2015
- Inventor(s)
  岸博子、張影、小林誠
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Filing Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-25460290
[Patent] SPC/Fyn/Rhoキナーゼシグナル伝達経路の阻害剤2015
- Inventor(s)
  岸博子、小林誠、張影
- Industrial Property Rights Holder
  山口大学
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2015-094671
- Filing Date
  2015-05-07
- Data Source
  KAKENHI-PROJECT-15K18970
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-23380077
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林誠、高柿了大、岸博子、張影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  山口大学、株式会社ラフィ‐ネインタ‐ナショナル
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2014-210258
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25893150
[Patent] 血管攣縮抑制剤2014
- Inventor(s)
  小林　誠、高柿了大、岸　博子、張　影、加治屋勝子、渡邉和晃
- Industrial Property Rights Holder
  国立大学法人山口大学、株式会社ラフィーネインターナショナル
- Industrial Property Rights Type
  特許
- Filing Date
  2014-10-14
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway to inhibit actin stress fiber formation2022
- Author(s)
  Ying Zhang, Qian Lu, Nan Li, Ming Xu, Tatsuo Miyamoto, Jing Liu
- Organizer
  第99回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of vimentin cleavage and calpain in the Ca2+-sensitization of vascular smooth muscle contraction2022
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Nan Li, Sei Kobayashi
- Organizer
  第99回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第63回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via AMPK-mediated eNOS activation and ROCK inhibition2021
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Paxillin is a novel signaling molecule which regulates abnormal vascular contraction mediated by an SPC/Fyn/Rho-kinase pathway2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn KOマウスの脳底動脈と前腸間膜動脈のスフィンゴシルホスホリルコリンに対する反応性について2021
- Author(s)
  森田知佳、張影、岸博子、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian Lu, Nan Li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 異常収縮刺激時Fynの活性化によるpaxillinのチロシンリン酸化について2021
- Author(s)
  張　影、呂　博超、森田　知佳、岸　博子、路　倩、李　楠、小林　誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] 血管平滑筋異常収縮のシグナル伝達におけるカルパインの役割の解明2021
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、李楠、小林誠
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in Ca2+-sensitization of vascular smooth muscle contraction2021
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound B from traditional Chinese medicine inhibits the Rho-kinase (ROK)-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine (SPC)2021
- Author(s)
  Minhui Xu, Min Zhang, Bochao Lyu, Qian lu, Nan li, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The inhibitory effect and mechanism exploration of compound H on sphingosylphosphorylcholine (SPC)-induced contraction in vascular smooth muscle2021
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Tomoka Morita, Hiroko Kishi, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Molecular mechanism of component T inhibiting abnormal vascular contraction and migration of MDA-MB-231 cancer cells2021
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会/第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] エイコサペンタエン酸によるチロシンキナーゼFynを介した肺高血圧症改善効果に関する研究2021
- Author(s)
  平石敬三、倉原琳、張影、山村彩、井上隆司、平野勝也
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] Deletion of Paxillin Attenuates Sphingosylphosphorylcholine (SPC)-Induced Abnormal Contraction of Vascular Smooth Muscle by Inhibiting Rho-kinase Activity2021
- Author(s)
  Ying Zhang, Tomoka Morita, Bochao Lyu, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Sphingosylphosphorylcholine induced contraction in basilar arteries of Fyn knockout mice.2021
- Author(s)
  Tomoka Morita, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第126回日本解剖学会総会・全国学術集会・第98回日本生理学会大会合同大会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Specific inhibitory effects of compound T, upon pre- or post-treated, on the sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization of vascular smooth muscle contraction through suppressing the Fyn/Rho-kinase signaling pathway, without affecting Ca2+-dependent contraction2021
- Author(s)
  Nan Li, Ying Zhang, Hiroko Kishi, Tomoka Morita, Bochao Lyu, Sei Kobayashi.
- Organizer
  第６3回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-21K06782
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおけるカルパインの活性化とビメンチン断片化の役割の解明2020
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、徐敏慧、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the mechanism of inhibiting the SPC-induced abnormal contraction.2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] Novel signaling molecules which can regulate both Ca2+-sensitization of vascular contraction and cancer cell migration2020
- Author(s)
  Sei Kobayashi, Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine（SPC）-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Compound H inhibits sphingosylphosphorylcholine-induced contraction via suppressing Fyn/Rho-kinase pathway in vascular smooth muscle2020
- Author(s)
  Qian Lu, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第62回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-20K07261
[Presentation] The role of calpain activation and vimentin cleavage in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2020
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Minhui Xu, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The inhibitory mechanism of T on MDA-MB-231 breast cancer cell migration and the SPC-induced abnormal contraction leading to vasospasm2020
- Author(s)
  Nan Li, Min Zhang, Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Role of paxillin in sphingosylphosphorylcholine (SPC)-induced Ca2+-sensitization contraction of vascular smooth muscle2020
- Author(s)
  Ying Zhang, Bochao Lyu, Tomoka Morita, Dan Cui, Hiroko Kishi, Min Zhang, Qian Lu, Nan Li, Eiji Ikeda, Sei Kobayashi
- Organizer
  第97回日本生理学会　3月17日～19日　誌上開催
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] スフィンゴシルホスホリルコリン（SPC）による血管平滑筋のCa2+感受性収縮におけるパキシリンの役割2020
- Author(s)
  張影、呂博超、森田知佳、崔丹、岸博子、張敏、路倩、李楠、池田栄二、小林誠
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Madagascine induces vasodilatation via activation of AMPK2020
- Author(s)
  Bochao Lyu, Dapeng Chen, Yuan Lin, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第６２回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋異常収縮における新規分子パキシリンの関与について2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋収縮のCa2+-sensitizationおよびCa2+依存性収縮におけるカルパインの関与2019
- Author(s)
  岸博子、路倩、森田知佳、張影、呂博超、張敏、李楠、小林誠
- Organizer
  2019年8月1 ～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  9th Federation of the Asian and Oceanian Physiological Societies (FAOPS) Congress
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 食用成分から、血管攣縮を抑制する水溶性物質を発見する。2019
- Author(s)
  豊川絢子、呂博超、張敏、張影、小林誠
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] The involvement of calpain in abnormal vascular smooth muscle contraction induced by SPC and U466192019
- Author(s)
  Hiroko Kishi, Qian Lu, Tomoka Morita, Ying Zhang, Bochao Lyu, Min Zhang, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] パキシリンは血管攣縮を制御する新規シグナル分子である2019
- Author(s)
  張　影、呂　博超、森田　知佳、崔　丹、岸　博子、張　敏、路　倩、李　楠、池田　栄二、小林　誠
- Organizer
  2019年8月1～3日、第61回日本平滑筋学会総会、名古屋大学　野依記念学術交流館
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Direct Fyn-paxillin binding controls migration of coronary artery smooth muscle cells.2019
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, Qian Lu, Nan Li, Sei Kobayashi
- Organizer
  2019年3月28 - 30日、第9回FAOPS大会　神戸コンベンションセンター
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 肺動脈性肺高血圧症に対するエイコサペンタエン酸の改善効果2019
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司、平野勝也
- Organizer
  2019年11月23～24日、第71回日本生理学会中国四国地方会、山口大学小串キャンパス（医学部）総合研究棟Ａ（医修館）
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、井上隆司
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  Bochao Lyu, Min Zhang, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Omega-3 and omega-6 docosapentaenoic acid (DPA) equally inhibit the Ca2+-sensitization of abnormal vascular contractions via inhibiting the Rho-kinase activation and translocation.2018
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, and Sei Kobayashi
- Organizer
  第95回日本生理学会大会サンポートホール高松・かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway: Part II2018
- Author(s)
  Hiroko Kishi, Miki Kajima, Katsuko Kajiya, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタエン酸 (DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張　敏、呂　博超、岸博子、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn-mediated tyrosine phosphorylation of a novel signaling molecule, paxillin controls stress fiber formation and migration of cancer cells2018
- Author(s)
  Shiori Yokobayashi, Ying Zhang, Takafumi Okamoto, Tomoka Morita, Hiroko Kishi, Takeshi Yamamoto, Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  張敏、張影、呂博超、高柿了大、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂　博超、張　敏、森田知佳、路　倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Fyn-mediated tyrosine phosphorylation of a novel signaling molecule, paxillin controls stress fiber formation and migration of cancer cells2018
- Author(s)
  Shiori Yokobayashi, Ying Zhang, Takafumi Okamoto, Tomoka Morita, Hiroko Kishi, Takeshi Yamamoto, Sei Kobayashi1
- Organizer
  第95回日本生理学会大会サンポートホール高松・かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway: Part II2018
- Author(s)
  Hiroko Kishi, Miki Kajima, Katsuko Kajiya, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第95回日本生理学会大会サンポートホール高松・かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] 活性型FynチロシンキナーゼのパキシリンN末端への直接結合は血管平滑筋細胞のストレスファイバー形成と細胞遊走を制御する2018
- Author(s)
  張影、岸博子、呂博超、張敏、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] 血管平滑筋のCa2+非依存性収縮と細胞遊走を制御する新規シグナル分子の同定2018
- Author(s)
  張影、松永一真、岡本嵩史、呂博超、張敏、森田知佳、岸博子、小林誠
- Organizer
  筋生理の集い
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Contribution of tyrosine kinase FYN to vascular remodeling in pulmonary arterial hypertension2018
- Author(s)
  Hiraishi Keizo, Kurahara Lin, Zhang Ying, Yamamura Aya, Kishi Hiroko, Kobayashi Sei, Koga Kaori, Onitsuka Miki, Inoue Ryuji
- Organizer
  第95回日本生理学会大会サンポートホール高松・かがわ国際会議場
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Compound A suppresses the Fyn/Rho-kinase mediated Ca2+-sensitization of vascular smooth muscle contraction2018
- Author(s)
  呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction.2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] エイコサペンタエン酸（EPA）による肺動脈高血圧病態の改善効果2018
- Author(s)
  倉原　琳、平石　敬三、張　影、山村　彩、岸　博子、小林　誠、井上　隆司
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] Omega-3 and omega-6 docosapentaenoic acid (DPA) equally inhibit the Ca2+-sensitization of abnormal vascular contractions via inhibiting the Rho-kinase activation and translocation.2018
- Author(s)
  Ying Zhang, Min Zhang, Bochao Lyu, Hiroko Kishi, Tomoka Morita, and Sei Kobayashi
- Organizer
  第95回日本生理学会大会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] ドコサペンタ塩酸(DPA)は、n-3とn-6の両系統とも同じ力価で、Rhoキナーゼの細胞内移動と活性化を抑制する事によって血管異常収縮を抑制する2018
- Author(s)
  張影、張敏、呂博超、岸博子、森田知佳、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Discovery of novel compound from soybean which selectively inhibits the normal vascular contraction leading to vasospasm2018
- Author(s)
  Min Zhang, Ying Zhang, Bochao Lyu, Ryodai Takagaki, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  2018年10月27 - 28日、第70回日本生理学会中国四国地方会、愛媛大学医学部　創立40周年記念講堂　(松山)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] SPC/Fyn/ROK系による血管平滑筋収縮のCa2+-sensitizationにおける、カルパインの役割2018
- Author(s)
  岸博子、張影、森田知佳、呂博超、張敏、路倩、小林誠
- Organizer
  第60回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 血管攣縮と癌細胞遊走の両方を阻止できる新規の水溶性食品成分の発見2018
- Author(s)
  浅田　充夫、呂博超、張敏、張影、岸博子、森田知佳、小林誠
- Organizer
  2018年8月16 - 18日、第60回日本平滑筋学会総会、東京慈恵会医科大学　１号館講堂　(東京)
- Data Source
  KAKENHI-PROJECT-18K06875
[Presentation] チロシンキナーゼFYNが肺動脈高血圧の病態生理に果たす役割2017
- Author(s)
  倉原琳、平石敬三、張影、山村彩、岸博子、小林誠、古賀佳織、鬼塚美樹、阿部弘太郎、塩井成留実、井上隆司
- Organizer
  第68回西日本生理学会　福岡大学中央図書館多目的ホール
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2017
- Author(s)
  張敏、張影、呂博超、岸博子、加治屋勝子、森田知佳、小林誠。
- Organizer
  第59回日本平滑筋学会総会　福岡大学図書館・多目的ホール
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Tyrosine phosphorylation of paxillin regulates migration and invasion of cancer cells2017
- Author(s)
  Takafumi Okamoto, Ying Zhang, Kazumasa Matsunaga, Shiori Yokobayashi, Tomoka Morita, Hiroko Kishi, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] Tyrosine phosphorylation of paxillin regulates migration of cancer cells2017
- Author(s)
  Takafumi Okamoto, Ying Zhang, Kazumasa Matsunaga, Shiori Yokobayashi, Tomoka Morita, Hiroko Kishi, and Sei Kobayashi
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松市　アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] スフィンゴシルホスホリルコリンが誘発する血管平滑筋異常収縮シグナル分子の細胞内局在の変化の検討2017
- Author(s)
  岸博子、張影、加治屋勝子、森田知佳、呂博超、張敏、小林誠。
- Organizer
  第59回日本平滑筋学会総会　福岡大学図書館・多目的ホール
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Paxillin as a novel signaling molecule regulates actin stress fiber formation and migration of vascular smooth muscle cells by its N-terminus binding to active Fyn2017
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] パキシリンはN末端と活性型Fynとの相互作用により血管平滑筋細胞遊走を制御する2017
- Author(s)
  張影、岸博子、森田知佳、呂博超、張敏、横林志織、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The novel compound from soybean strongly and selectively inhibits the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2017
- Author(s)
  張敏、張影、呂博超、岸博子、加治屋勝子、森田知佳、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] パキシリンはN末端と活性型Fynとの相互作用により血管平滑筋細胞遊走を制御する2017
- Author(s)
  張　影、岸　博子、森田　知佳、呂　博超、張　敏、横林　志織、小林　誠
- Organizer
  第59回日本平滑筋学会総会　福岡大学図書館・多目的ホール
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Paxillin as a novel signaling molecule regulates actin stress fiber formation and migration of vascular smooth muscle cells by its N-terminus binding to the active Fyn2017
- Author(s)
  Ying Zhang, Hiroko Kishi, Katsuko Kajiya, Tomoka Morita, Sei Kobayashi.
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松市アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2017
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomoka Morita, Bochao Lyu, Min Zhang, Xiaoyan Li, Sei Kobayashi
- Organizer
  第94回日本生理学会大会
- Place of Presentation
  アクトシティ浜松 (浜松)
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] スフィンゴシルホスホリルコリンが誘発する血管平滑筋異常収縮シグナル分子の細胞内局在の変化の検討2017
- Author(s)
  岸博子、張影、加治屋勝子、森田知佳、呂博超、張敏、小林誠
- Organizer
  第59回日本平滑筋学会総会
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The involvement of membrane rafts in the signal transduction of abnormal vascular smooth muscle contraction mediated by SPC/Fyn/ROK pathway2017
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomoka Morita, Bochao Lyu, Min Zhang, Xiaoyan Li, Sei Kobayashi
- Organizer
  第94回日本生理学会
- Place of Presentation
  浜松市　アクトシティ浜松
- Year and Date
  2017-03-28
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The novel compound from soybean has a strong inhibitory effect on the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2016
- Author(s)
  張敏、張影、呂博超、岸博子、森田知佳、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京)
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] 新規に発見したシグナル分子paxillinの癌細胞の遊走・浸潤における重要性2016
- Author(s)
  岡本嵩史、松永一真、横林志織、張影、小林誠
- Organizer
  第68回日本生理学会中国四国地方会
- Place of Presentation
  岡山大学Junko Fukutake ホール
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The MLC20 monophosphorylation-dependent and -independent Ca2+-sensitization, respectively at the early and late phase of vascular smooth muscle absormal contraction2016
- Author(s)
  Hiroko Kishi, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第93回日本生理学会
- Place of Presentation
  札幌コンベンションセンター(札幌）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Compound X inhibits the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine2016
- Author(s)
  Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第68回日本生理学会中国四国地方会
- Place of Presentation
  岡山大学Junko Fukutake ホール
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] The novel compound from soybean has a strong inhibitory effect on the Rho-kinase-mediated Ca2+-sensitization of vascular smooth muscle contraction2016
- Author(s)
  張敏、張影、呂博超、岸博子、森田知佳、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学・高木会館２号館地下１階南講堂
- Year and Date
  2016-12-17
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] N-terminal tyrosine phosphorylation-dependent intracellular localization of paxillin regulates stress fiber formation and the migration and invasion of breast cancer cells2016
- Author(s)
  Kazumasa Matsunaga, Takafumi Okamoto, Ying Zhang, Sei Kobayashi
- Organizer
  第93回日本生理学会
- Place of Presentation
  札幌コンベンションセンター(札幌）
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Compound X inhibits the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction induced by a spasmogen, sphingosylphosphorylcholine2016
- Author(s)
  Bochao Lyu, Ying Zhang, Hiroko Kishi, Tomoka Morita, Sei Kobayashi
- Organizer
  第68回日本生理学会中国四国地方会
- Place of Presentation
  岡山大学Junko Fukutakeホール (岡山)
- Year and Date
  2016-11-05
- Data Source
  KAKENHI-PROJECT-16K08496
[Presentation] The MLC20 monophosphorylation-dependent and -independent Ca2+-sensitization, respectively at the early and late phase of vascular smooth muscle abnormal contraction2016
- Author(s)
  Hiroko Kishi, Ying Zhang, Tomoka Morita, Bochao Lyu, Min Zhang, Sei Kobayashi
- Organizer
  第93回日本生理学会大会
- Place of Presentation
  札幌コンベンションセンター (札幌)
- Year and Date
  2016-03-22
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮を特異的に抑制する食用植物由来成分の探索2015
- Author(s)
  吉井大智、張　影、岸　博子、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、ミオシン軽鎖リン酸化の検討2015
- Author(s)
  岸　博子、張　影、呂　博超、張　敏、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 活性化FynとパキシリンN末端との相互作用は血管平滑筋細胞のストレスファイバー形成と細胞遊走において重要な役割を担う2015
- Author(s)
  張影、岸博子、加治屋勝子、呂博超、張敏、森田智佳、小林誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟(宇部）
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] Docosapentaenoic acid (DPA) n-6不飽和脂肪酸による新たな血管攣縮の抑制作用の発見とその分子機構の解明2015
- Author(s)
  張影、張敏、呂博超、岸博子、小林誠
- Organizer
  第67回日本生理学会中国四国地方会
- Place of Presentation
  米子コンベンションセンター小ホール(米子）
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] 血管平滑筋異常収縮を特異的に抑制する食用植物由来成分の探索2015
- Author(s)
  吉井大智、張影、岸博子、小林誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟(宇部）
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] 活性化FynとパキシリンN末端との相互作用は血管平滑筋細胞のストレスファイバー形成と細胞遊走において重要な役割を担う2015
- Author(s)
  張　影、岸　博子、加治屋勝子、呂　博超、張　敏、森田　智佳、小林　誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟 (宇部)
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Docosapentaenoic acid (DPA) n-6 不飽和脂肪酸により新たな血管攣縮の抑制作用の発見とその分子機構の解明2015
- Author(s)
  張　影、張　敏、呂　博超、岸　博子、小林　誠
- Organizer
  第67回日本生理学会中国四国地方会
- Place of Presentation
  米子コンベンションセンター小ホール (米子)
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Paxillinノックダウンが癌細胞の浸潤・遊走、およびストレスファイバー形成に与える影響について2015
- Author(s)
  Kazumasa Matsunaga, Ying Zhang, Sei Kobayashi
- Organizer
  第67回日本生理学会中国四国地方会
- Place of Presentation
  米子コンベンションセンター小ホール(米子）
- Year and Date
  2015-10-24
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、ミオシン軽鎖リン酸化の検討2015
- Author(s)
  岸博子、張影、呂博超、張敏、小林誠
- Organizer
  第57回日本平滑筋学会総会
- Place of Presentation
  山口大学小串キャンパス(医学部)総合研究棟(宇部）
- Year and Date
  2015-08-25
- Data Source
  KAKENHI-PROJECT-15K18970
[Presentation] 血管平滑筋収縮のカルシウム感受性亢進における、タンパク質分解酵素の関与の可能性2014
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学 (東京都)
- Year and Date
  2014-12-06
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The time course of Fyn and ROK activation in the signal transduction of abnormal vascular smooth muscle contraction2014
- Author(s)
  Hiroko Kishi, Ying Zhang, Ryodai Takagaki, Kenji Miyanari, Tomohiko Kimura, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性2014
- Author(s)
  張　影
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル（神奈川県）
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Important role of cell membrane microdomain for Ca2+-sensitization of vascular smooth muscle contraction2014
- Author(s)
  Katsuko Kajiya, Kazutaka Nojimoto, Hiroko Kishi, Yuichi Takada, Ying Zhang, Sei Kobayashi
- Organizer
  第91回日本生理学会大会
- Place of Presentation
  鹿児島大学郡元キャンパス(鹿児島)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋アクチン・ストレスファイバーの形成を担う新規シグナル分子の同定とその機能解析2013
- Author(s)
  張　影、岸　博子、加治屋勝子、宮成健司、木村友彦、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The interaction of Fyn and a cytoskeleton-related protein which is identified as a novel signaling molecule in SPC/Fyn/ROK pathway to mediate abnormal VSM contraction2013
- Author(s)
  Hiroko Kishi, Ying Zhang, Katsuko Kajiya, Tomohiko Kimura, Kenji Miyanari, Sei Kobayashi
- Organizer
  第36回心筋代謝研究会
- Place of Presentation
  キヤノンマーケティングジャパン株式会社 3階ホール(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管異常収縮の新規シグナル分子として同定された細胞骨格関連分子の、Fynとの相互作用解析2013
- Author(s)
  岸　博子、張　影、加治屋勝子、高田雄一、宮成健司、木村友彦、野地本和孝、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 冠血管弛緩作用を有する新規ペプチドの探索: 続報2013
- Author(s)
  木村友彦、宮成健司、高柿了大、張影、岸博子、小林誠
- Organizer
  筋生理の集い
- Place of Presentation
  東京慈恵会医科大学(東京)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] 血管平滑筋異常収縮の病的シグナル伝達における細胞膜上マイクロドメインの新規機能2013
- Author(s)
  加治屋勝子、野地本和孝、岸　博子、張　影、高田雄一、木村友彦、宮成健司、小林　誠
- Organizer
  第55回日本平滑筋学会総会
- Place of Presentation
  旭川市大雪クリスタルホール(旭川)
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸　博子、張　影、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張影、岸博子、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Novel fish-derived peptide fragments which induce endothelium-dependent and -independent vasorelaxation
- Author(s)
  Tomohiko Kimura, Yuichi Takada, Katsuko Kajiya, Ying Zhang, Kenji Miyanari, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+-sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Katsuko Kajiya, Sei Kobayashi
- Organizer
  第１２０回日本解剖学会総会・全国学術集会/第９２回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場（神戸市）
- Year and Date
  2015-03-20 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] アクチン・ストレスファイバー形成における、新規シグナル分子パキシリンと活性型Fynチロシンキナーゼとの相互作用の重要性
- Author(s)
  張　影、岸　博子、宮成健司、木村友彦、高柿了大、呂　博超、小林　誠
- Organizer
  第56回日本平滑筋学会総会
- Place of Presentation
  新横浜プリンスホテル (横浜市)
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] SPC/Fyn/ROK経路による血管平滑筋収縮Ca2+感受性亢進のシグナル伝達における、FynおよびROK活性化の経時的変化の検討
- Author(s)
  岸博子、張影、宮成健司、木村友彦、高柿了大、呂博超、小林誠
- Organizer
  第５６回日本平滑筋学会
- Place of Presentation
  新横浜プリンスホテル（横浜市）
- Year and Date
  2014-08-06 – 2014-08-08
- Data Source
  KAKENHI-PROJECT-25893150
[Presentation] N-terminus of paxillin regulates actin stress fiber formation by binding to the active Fyn
- Author(s)
  Ying Zhang, Hiroko Kishi, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077
[Presentation] The novel role of calpain in SPC/Fyn/ROK pathway which mediates the signal transduction of abnormal vascular smooth muscle contraction
- Author(s)
  Hiroko Kishi, Ying Zhang, Kenji Miyanari, Tomohiko Kimura, Ryodai Takagaki, Bochao Lyu, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-25460290
[Presentation] Discovery of novel Salacia-derived components which specifically inhibit the ROK-mediated Ca2+- sensitization of vascular smooth muscle contraction
- Author(s)
  Kenji Miyanari, Kazutaka Nojimoto, Katsuko Kajiya, Yuichi Takada, Tomohiko Kimura, Ying Zhang, Hiroko Kishi, Sei Kobayashi
- Organizer
  第120回日本解剖学会総会全国学術集会・第92回日本生理学会大会合同大会
- Place of Presentation
  神戸国際会議場・展示場 (神戸市)
- Year and Date
  2015-03-21 – 2015-03-23
- Data Source
  KAKENHI-PROJECT-23380077

1. KOBAYASHI Sei (80225515)

# of Collaborated Projects: 8 results

# of Collaborated Products: 128 results
2. KISHI Hiroko (40359899)

# of Collaborated Projects: 8 results

# of Collaborated Products: 123 results
3. 森田知佳 (70763796)

# of Collaborated Projects: 4 results

# of Collaborated Products: 68 results
4. KAJIYA Katsuko (00379942)

# of Collaborated Projects: 2 results

# of Collaborated Products: 10 results
5. LYU Bochao

# of Collaborated Projects: 1 results

# of Collaborated Products: 18 results
6. ZHANG Min

# of Collaborated Projects: 1 results

# of Collaborated Products: 23 results
7. LU Qian

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. LI Nan

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
9. 宮本達雄

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐藤元彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 山村彩

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

ZHANG YING 張 影

ZHANG Ying 張 影

Research Projects

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Elucidation of the mechanism by which paxillin controls vascular abnormal contractionPrincipal Investigator

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中間径フィラメントビメンチンを介した新規血管平滑筋異常収縮シグナル伝達機構の解明

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Elucidation of the mechanism by which paxillin controls vascular abnormal contractionPrincipal Investigator

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Elucidation of the involvement of calpain and cytoskeletal proteins in the signal transduction of abnormal vascular smooth muscle contraction

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Searching for the novel signalling molecule in vascular abnormal contractionPrincipal Investigator

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Elucidation of the shared signaling pathways for intractable diseases in terms of cytoskeletal rearrangements

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Research for novel signaling molecule involving vascular smooth muscle abnormal contractionPrincipal Investigator

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Identification of food component which selectively inhibits abnormal vascular contraction

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[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm, Muscle Contraction and Cell Motility: Fundamentals and Developments, edited by Haruo Sugi2016

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[Book] Chapter 13, The pivotal role of cholesterol and membrane lipid rafts in the Ca2+-sensitization of vascular smooth muscle contraction leading to vasospasm. Muscle Contraction and Cell Motility: Fundamentals and Developments edited by Haruo Sugi.2016

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[Journal Article] Sulforaphane suppresses metastasis of triple-negative breast cancer cells by targeting the RAF/MEK/ERK pathway2022

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[Journal Article] Hesperetin Inhibits Sphingosylphosphorylcholine-Induced Vascular Smooth Muscle Contraction by Regulating the Fyn/Rho-Kinase Pathway2022

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[Journal Article] Paxillin controls actin stress fiber formation and migration of vascular smooth muscle cells by directly binding to the active Fyn2021

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[Journal Article] Eicosapentaenoic acid ameliorates pulmonary hypertension via inhibition of tyrosine kinase Fyn2020

Author(s)

ZHANG YING 張影

ZHANG Ying 張影