Endo Fumito 遠藤史人

… Alternative Names

ENDO Fumito 遠藤史人

Less

Researcher Number	10713307
Other IDs
Affiliation (Current)	2025: 名古屋大学, 環境医学研究所, 特任講師
Affiliation (based on the past Project Information) *help	2023 – 2024: 名古屋大学, 環境医学研究所, 特任講師 2015 – 2017: 名古屋大学, 環境医学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related / Transformative Research Areas, Section (III) / Neurology Except Principal Investigator Biological Sciences
Keywords	Principal Investigator アストロサイト / アルツハイマー病 / ミクログリア / エクソソーム / 筋萎縮性側索硬化症 Except Principal Investigator 細胞外環境 / 脊髄 / 脊髄環境 / 環境 / グリア / 神経変性疾患

マルチオミクス解析による神経炎症を標的としたアルツハイマー病の治療法の開発Principal Investigator
- Principal Investigator
  
  遠藤史人
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (A)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nagoya University
疾患特異的アストロサイトを標的としたアルツハイマー病の治療法の開発Principal Investigator
- Principal Investigator
  
  遠藤史人
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nagoya University
アストロサイトに着目した筋萎縮性側索硬化症の分子病態解明と治療標的の同定Principal Investigator
- Principal Investigator
  
  遠藤史人
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Neurology
- Research Institution
  Nagoya University
Spinal cord environment: elucidating the mechanism of neurodegeneration through glia-neuron interaction
- Principal Investigator
  
  Yamanaka Koji
- Project Period (FY)
  2011 – 2015
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Biological Sciences
- Research Institution
  Nagoya University
  The Institute of Physical and Chemical Research

All 2023 2018 2017 2016 2015 2014 2013 2012

All Journal Article Presentation

[Journal Article] Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice2018
- Author(s)
  Watanabe Seiji、Komine Okiru、Endo Fumito、Wakasugi Keisuke、Yamanaka Koji
- Journal Title
  
  Journal of Neurochemistry
  
  Volume: 145 Issue: 1 Pages: 80-89
- DOI
  10.1111/jnc.14285
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K14963, KAKENHI-PROJECT-17H04986, KAKENHI-PROJECT-16K09671, KAKENHI-PROJECT-17K07329
[Journal Article] A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis2017
- Author(s)
  Itsuki Anzai, Eiichi Tokuda, Atsushi Mukaiyama, Shuji Akiyama, Fumito Endo, Koji Yamanaka, Hidemi Misawa, and Yoshiaki Furukawa
- Journal Title
  
  Protein Science
  
  Volume: 26 Issue: 3 Pages: 484-496
- DOI
  10.1002/pro.3094
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-15H01566, KAKENHI-PROJECT-16H04768, KAKENHI-PROJECT-15H06588, KAKENHI-PROJECT-15K14480, KAKENHI-PROJECT-16K09671
[Journal Article] Neuroinflammation in motor neuron disease.2016
- Author(s)
  Endo F, Komine O, Yamanaka K.
- Journal Title
  
  Clinical and Experimental Neuroimmunology
  
  Volume: 7 Issue: 2 Pages: 126-138
- DOI
  10.1111/cen3.12309
- NAID
  120005672307
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PUBLICLY-16H01336, KAKENHI-PROJECT-26293208, KAKENHI-PROJECT-16K09671
[Journal Article] Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS.2016
- Author(s)
  Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, Jin S, Mancias P, Kiyama H, *Yamanaka K.
- Journal Title
  
  EMBO Molecular Medicine
  
  Volume: 8 Issue: 12 Pages: 1421-1437
- DOI
  10.15252/emmm.201606403
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-16H01336, KAKENHI-PROJECT-16H05117, KAKENHI-PROJECT-26293208, KAKENHI-PROJECT-15K19321, KAKENHI-PROJECT-25860252, KAKENHI-PROJECT-26830046, KAKENHI-PROJECT-16K09671
[Journal Article] Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model.2015
- Author(s)
  Chhangani D, Endo F, Amanullah A, Upadhyay A, Watanabe S, Mishra R, Yamanaka K, Mishra A
- Journal Title
  
  Neurobiology of Disease
  
  Volume: 86 Pages: 16-16
- DOI
  10.1016/j.nbd.2015.11.017
- Peer Reviewed / Acknowledgement Compliant / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-25860252, KAKENHI-PLANNED-23111006, KAKENHI-PROJECT-26293208
[Journal Article] Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells.2015
- Author(s)
  Endo F, Komine O, et al.
- Journal Title
  
  Cell Reports
  
  Volume: 11 Pages: 592-604
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-23111006
[Journal Article] SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.2014
- Author(s)
  Watanabe S, Ageta-Ishihara N, Nagatsu S, Takao K, Komine O, Endo F, Miyakawa T, Misawa H, Takahashi R, Kinoshita M, Yamanaka K.
- Journal Title
  
  Mol Brain
  
  Volume: 7 Issue: 1 Pages: 62-62
- DOI
  10.1186/s13041-014-0062-1
- Peer Reviewed / Acknowledgement Compliant / Open Access
- Data Source
  KAKENHI-PROJECT-221S0003, KAKENHI-PLANNED-23111006, KAKENHI-PUBLICLY-25116514, KAKENHI-PUBLICLY-25116526, KAKENHI-PROJECT-25293020, KAKENHI-PROJECT-25350989, KAKENHI-PROJECT-25860252, KAKENHI-PUBLICLY-26115529, KAKENHI-PROJECT-26293208, KAKENHI-PROJECT-26440095, KAKENHI-PLANNED-23111002, KAKENHI-PROJECT-25242078
[Journal Article] E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity.2013
- Author(s)
  MISHRA Amit, MAHESHIWARI Megha, CHHANGANI Deepak, FUJIMORI-TONOU Noriko, ENDO Fumito, JOSHI A.Prakashi, JANA N.Ranjan, YAMANAKA Koji
- Journal Title
  
  Neurobiology of Aging
  
  Volume: 34 Issue: 4 Pages: 1310.e11-1310.e23
- DOI
  10.1016/j.neurobiolaging.2012.08.016
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PLANNED-23111006
[Presentation] Molecular basis of astrocyte diversity and morphology and its relation to Alzheimer’s disease2023
- Author(s)
  Fumito Endo, Atsushi Kasai, Hitoshi Hashimoto, Viviana Gradinaru, Riki Kawaguchi, Baljit S. Khakh
- Organizer
  第46回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PUBLICLY-23H04160
[Presentation] Molecular basis of astrocyte diversity and morphology and its relation to Alzheimer’s disease2023
- Author(s)
  Fumito Endo, Atsushi Kasai, Hitoshi Hashimoto, Viviana Gradinaru, Riki Kawaguchi, Baljit S. Khakh
- Organizer
  第46回日本神経科学大会
- Invited
- Data Source
  KAKENHI-PROJECT-23K06963
[Presentation] Astrocytic Gi-GPCRs ameliorate cognitive dysfunction in Alzheimer’s disease mice2023
- Author(s)
  Fumito Endo, Vijaya Pandey, Zhe Qu, Viviana Gradinaru, James Wohlschlegel, Riki Kawaguchi, Baljit Khakh
- Organizer
  第50回内藤コンファレンス
- Data Source
  KAKENHI-PUBLICLY-23H04160
[Presentation] Astrocyte-derived extracellular vesicles contribute to the propagation of pathogenic protein in ALS.2017
- Author(s)
  Endo F. Kurita T, Yamanaka K.
- Organizer
  XXIII World Congress of Neurology(第23回世界神経学会議)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09671
[Presentation] Astrocyte-derived extracellular vesicles contribute to the propagation of pathogenic protein in ALS.2017
- Author(s)
  Endo F, Yamanaka K.
- Organizer
  28th International symposium on ALS/MND
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K09671
[Presentation] アストロサイト由来エクソソームを介したALS病原タンパク質伝播に関する検討.2017
- Author(s)
  遠藤史人，山中宏二.
- Organizer
  第40回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-16K09671
[Presentation] Dysregulation of TGF-β signaling facilitates motor neurodegeneration of ALS mice2016
- Author(s)
  Endo F, Yamanaka K
- Organizer
  第39回日本神経科学大会
- Place of Presentation
  横浜
- Year and Date
  2016-07-20
- Data Source
  KAKENHI-PROJECT-16K09671
[Presentation] Dysregulation of neuronal TGF-beta signaling contributes to neurodegeneration in mutant SOD1 mice2016
- Author(s)
  Endo F, Miyazaki A, Yamanaka K
- Organizer
  第57回日本神経学会学術大会
- Place of Presentation
  神戸
- Year and Date
  2016-05-18
- Data Source
  KAKENHI-PROJECT-16K09671
[Presentation] Astrocyte-derived TGF-β1 accelerates disease progression in ALS mice by interfering with neuroprotective functions of microglia and T cells.2014
- Author(s)
  Fumito Endo et al.
- Organizer
  9th Brain Research Conference-Neuroprotection
- Place of Presentation
  ワシントンD.C.（米国）
- Year and Date
  2014-11-13
- Data Source
  KAKENHI-PLANNED-23111006
[Presentation] 筋萎縮性側索硬化症における神経炎症.2014
- Author(s)
  遠藤史人、山中宏二
- Organizer
  第55回日本神経学会学術大会シンポジウム
- Place of Presentation
  福岡国際会議場（福岡）
- Year and Date
  2014-05-24
- Invited
- Data Source
  KAKENHI-PLANNED-23111006
[Presentation] The roles of TGF-β1 in the disease progression of ALS mice.2013
- Author(s)
  Fumito Endo et al.
- Organizer
  Neuroscience 2013
- Place of Presentation
  San Diego（米国）
- Year and Date
  2013-11-11
- Invited
- Data Source
  KAKENHI-PLANNED-23111006
[Presentation] Roles of TGF-β1 in the disease progression of ALS mice.2012
- Author(s)
  Fumito Endo et al.
- Organizer
  23rd international symposium on ALS/MND
- Place of Presentation
  Chicago, USA
- Year and Date
  2012-12-05
- Data Source
  KAKENHI-PLANNED-23111006

1. Yamanaka Koji (80446533)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
2. MISAWA Hidemi (80219617)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. YAMASHITA Hirofumi (60402913)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. MORIWAKI Yasuhiro (00392150)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. KOMINE Okiru (00456211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. WATANABE Seiji (70633577)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. TAKAO Keizo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 宮川剛

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 阿部修

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 高尾昌樹

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 渡辺雅彦

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
12. 石原健

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
13. 高尾英正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
14. 高橋良輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 伊佐正

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 饗場篤

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
17. 高橋淑子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
18. 木下専

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
19. 古川良明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Endo Fumito 遠藤 史人

ENDO Fumito 遠藤 史人

Research Projects

Research Products

Co-Researchers

マルチオミクス解析による神経炎症を標的としたアルツハイマー病の治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

疾患特異的アストロサイトを標的としたアルツハイマー病の治療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

アストロサイトに着目した筋萎縮性側索硬化症の分子病態解明と治療標的の同定Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Spinal cord environment: elucidating the mechanism of neurodegeneration through glia-neuron interaction

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Intracerebroventricular administration of Cystatin C ameliorates disease in SOD1-linked amyotrophic lateral sclerosis mice2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A misfolded dimer of Cu/Zn-superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Neuroinflammation in motor neuron disease.2016

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS.2016

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mahogunin ring finger 1 confers cytoprotection against mutant SOD1 aggresomes and is defective in an ALS mouse model.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells.2015

Author(s)

Journal Title

Data Source

[Journal Article] SIRT1 overexpression ameliorates a mouse model of SOD1-linked amyotrophic lateral sclerosis via HSF1/HSP70i chaperone system.2014

Author(s)

Journal Title

DOI

Data Source

[Journal Article] E6-AP association promotes SOD1 aggresomes degradation and suppresses toxicity.2013

Author(s)

Journal Title

DOI

Data Source

[Presentation] Molecular basis of astrocyte diversity and morphology and its relation to Alzheimer’s disease2023

Author(s)

Organizer

Data Source

[Presentation] Molecular basis of astrocyte diversity and morphology and its relation to Alzheimer’s disease2023

Author(s)

Organizer

Data Source

[Presentation] Astrocytic Gi-GPCRs ameliorate cognitive dysfunction in Alzheimer’s disease mice2023

Author(s)

Organizer

Endo Fumito 遠藤史人

ENDO Fumito 遠藤史人