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Hukuda Koji  福田 康二

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Fukuda Koji  福田 康二

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Researcher Number 10722548
Other IDs
Affiliation (Current) 2023: 金沢大学, がん進展制御研究所, 助教
Affiliation (based on the past Project Information) *help 2017 – 2021: 金沢大学, がん進展制御研究所, 助教
2015 – 2016: 金沢大学, がん進展制御研究所, 特任助手
2014: 金沢大学, がん進展制御研究所, 博士研究員
Review Section/Research Field
Principal Investigator
Respiratory organ internal medicine / Basic Section 50020:Tumor diagnostics and therapeutics-related
Keywords
Principal Investigator
EMT / miR-200 / ALK融合遺伝子陽性肺癌 / ALK / 薬剤耐性 / EGFR / EGFR肺癌 / AXL / EGFR変異肺癌 / 第3世代-TKI … More / ALK肺がん / 肺がん / オシメルチニブ / GSK-3 / miR200c / osimertinib / 耐性 / HDAC阻害薬 / KRAS / ARID1A / Osimertinib / 中枢神経系転移 / CNS / 中枢神経系 / 髄膜癌腫症 Less
  • Research Projects

    (4 results)
  • Research Products

    (14 results)
  • Co-Researchers

    (3 People)
  •  EGFR肺癌の髄膜癌腫症におけるEGFR-TKI耐性克服治療の開発Principal Investigator

    • Principal Investigator
      福田 康二
    • Project Period (FY)
      2021 – 2023
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kanazawa University
  •  Development of treatment to overcome TKI resistance caused by EMT in lung cancerPrincipal Investigator

    • Principal Investigator
      Fukuda Koji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 50020:Tumor diagnostics and therapeutics-related
    • Research Institution
      Kanazawa University
  •  Development of ALK-TKI-resistant treatment due to EMT of ALK lung cancerPrincipal Investigator

    • Principal Investigator
      Fukuda Koji
    • Project Period (FY)
      2016 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kanazawa University
  •  Development of therapies for overcoming EMT-associated irreversible tyrosine kinase inhibitor resistance in EGFR lung cancerPrincipal Investigator

    • Principal Investigator
      Fukuda Koji
    • Project Period (FY)
      2014 – 2015
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Respiratory organ internal medicine
    • Research Institution
      Kanazawa University

All 2021 2020 2019 2018 2016

All Journal Article Presentation

  • [Journal Article] Trametinib overcomes KRAS-G12V-induced osimertinib resistance in a leptomeningeal carcinomatosis model of EGFR-mutant lung cancer2021

    • Author(s)
      Fukuda Koji、Otani Sakiko、Takeuchi Shinji、Arai Sachiko、Nanjo Shigeki、Tanimoto Azusa、Nishiyama Akihiro、Naoki Katsuhiko、Yano Seiji
    • Journal Title

      Cancer Science

      Volume: 112 Issue: 9 Pages: 3784-3795

    • DOI

      10.1111/cas.15035

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K17213, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-21K07172
  • [Journal Article] Glycogen synthase kinase‐3 inhibition overcomes epithelial‐mesenchymal transition‐associated resistance to osimertinib in EGFR ‐mutant lung cancer2020

    • Author(s)
      Fukuda Koji、Takeuchi Shinji、Arai Sachiko、Kita Kenji、Tanimoto Azusa、Nishiyama Akihiro、Yano Seiji
    • Journal Title

      Cancer Science

      Volume: 111 Issue: 7 Pages: 2374-2384

    • DOI

      10.1111/cas.14454

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K08516, KAKENHI-PROJECT-19H03665, KAKENHI-PROJECT-18K07261
  • [Journal Article] GSK-3 inhibition overcomes EMT-associated resistance to osimertinib in EGFR mutant lung cancer2020

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Sachiko Arai, Kenji Kita, Azusa Tanimoto, Akihiro Nishiyama, Seiji Yano
    • Journal Title

      Cancer Science

      Volume: -

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Journal Article] Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of ALK Mutation Status2019

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Sachiko Arai, Ryohei Katayama, et al
    • Journal Title

      Cancer Reseach

      Volume: 79 Pages: 1658-1670

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Journal Article] Epithelial-to-Mesenchymal Transition Is a Mechanism of ALK Inhibitor Resistance in Lung Cancer Independent of ALK Mutation Status.2019

    • Author(s)
      Fukuda K, Takeuchi S, Arai S, Katayama R, Nanjo S, Tanimoto A, Nishiyama A, Nakagawa T, Taniguchi H, Suzuki T, Yamada T, Nishihara H, Ninomiya H, Ishikawa Y, Baba S, Takeuchi K, Horiike A, Yanagitani N, Nishio M, Yano S.
    • Journal Title

      Cancer Resarch

      Volume: 79 Pages: 1658-1670

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Presentation] Epithelial-to-mesenchymal transition is a mechanism of ALK inhibitor resistance in lung cancer independent of ALK mutation status.2019

    • Author(s)
      福田康二
    • Organizer
      IASLC 2019 World Conference on Lung Cancer. 2019年9月
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Presentation] 肺がんにおいて上皮間葉転換はALK阻害薬耐性メカニズムとして機能する.2019

    • Author(s)
      福田 康二
    • Organizer
      第23回日本がん分子標的治療学会学術集会 2019年6月
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Presentation] EMTに起因した肺癌の分子標的薬耐性の克服2018

    • Author(s)
      福田康二
    • Organizer
      第5回 Medical Frontier Consortium beyond the Organcentric Dogma
    • Data Source
      KAKENHI-PROJECT-16K19447
  • [Presentation] Heterogeneity of epithelial-to-mesenchymal transition and resistance mutation in ALK inhibitor-resistant lung cancer and its circumvention2018

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Sachiko Arai, Ryohei Katayama, Shigeki Nanjo, Azusa Tanimoto, Akihiro Nishiyama, Takeshi Suzuki, Kengo Takeuchi, Makoto Nishio, Seiji Yano.
    • Organizer
      Fifth AACR-IASLC International Joint Conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19447
  • [Presentation] Heterogeneity of epithelial-to-mesenchymal transition and resistance mutation in ALK inhibitor-resistant lung cancer and its circumvention2018

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Sachiko Arai, Ryohei Katayama, Shigeki Nanjo, Azusa Tanimoto, Akihiro Nishiyama, Takeshi Suzuki, Kengo Takeuchi, Makoto Nishio, Seiji Yano.
    • Organizer
      The 1st NanoLSI International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19447
  • [Presentation] ALK転座陽性肺癌においてEMTは独立した機構として関与する2018

    • Author(s)
      福田康二、竹内伸司、片山量平、南條成輝、山田忠明、鈴木健之、竹内健吾、西尾誠人、矢野聖二
    • Organizer
      第77回日本癌学会学術総会 2018
    • Data Source
      KAKENHI-PROJECT-18K07261
  • [Presentation] HDAC inhibition overcomes crizotinib-resistance by mesenchymal-epithelial transition (MET) in EML4-ALK lung cancer cells2016

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Ryohei Katayama, Shigeki Nanjo, Kengo Takeuchi, Hiroshi Nishihara, Makoto Nishio, Seiji Yano.
    • Organizer
      第75回日本癌学会学術総会
    • Place of Presentation
      横浜
    • Year and Date
      2016-10-06
    • Data Source
      KAKENHI-PROJECT-16K19447
  • [Presentation] HDAC inhibition overcomes crizotinib-resistance by inducing mesenchymal-epithelial reverting transition (MERT) via miR-200c up-regulation in EML4-ALK lung cancer cells.2016

    • Author(s)
      Koji Fukuda, Shigeki Nanjo, Shinji Takeuchi, Tadaaki Yamada, Ryohei Katayama, Kengo Takeuchi, Hiroshi Nishihara, Seiji Yano.
    • Organizer
      Tenth AACR-JCA Joint Conference
    • Place of Presentation
      Maui, Hawaii, USA
    • Year and Date
      2016-02-16
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-26860603
  • [Presentation] HDAC inhibition overcomes crizotinib-resistance by mesenchymal-epithelial transition (MET) in EML4-ALK lung cancer cells2016

    • Author(s)
      Koji Fukuda, Shinji Takeuchi, Ryohei Katayama, Shigeki Nanjo, Kengo Takeuchi, Hiroshi Nishihara, Makoto Nishio, Seiji Yano.
    • Organizer
      IASLC 17th world conference on lung cancer
    • Place of Presentation
      ウイーン、オーストリア
    • Year and Date
      2016-12-04
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K19447
  • 1.  Shinji Takeuchi (90565384)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 6 results
  • 2.  Seiji Yano (30294672)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  大谷 咲子
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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