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Li Junjun  李 俊君

… Alternative Names

LI Junjun  李 俊君

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Researcher Number 10723786
Other IDs
  • ORCIDhttps://orcid.org/0000-0002-7473-4918
Affiliation (Current) 2025: 大阪大学, 大学院工学研究科, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2023 – 2025: 大阪大学, 大学院工学研究科, 特任准教授(常勤)
2022: 大阪大学, 大学院医学系研究科, 特任助教
2021: 大阪大学, 医学系研究科, 特任助教(非常勤)
2019 – 2021: 大阪大学, 医学系研究科, 特任助教(常勤)
2017 – 2019: 大阪大学, 医学系研究科, 特任研究員(常勤)
Review Section/Research Field
Principal Investigator
Basic Section 90110:Biomedical engineering-related / Basic Section 90120:Biomaterials-related / Intelligent mechanics/Mechanical systems
Except Principal Investigator
Basic Section 55030:Cardiovascular surgery-related / Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields / Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
Keywords
Principal Investigator
maturation / cardiomyocytes / pluripotent stem cells / regenerative medicine / Maturation / tissue engineering / drug assessment / Drug assessment / Cardiomyocytes / Pluripotent stem cells … More / 自発進行波 / 成熟心筋 / 心筋梗塞治療 / cell maturation / pluripotent stem cell / Traveling wave / Cardiomyocyte / iPS cell / organ on chip / cardiomyocyte maturation … More
Except Principal Investigator
心筋梗塞治療 / ヒトiPS由来心筋細胞 / ファイバー / デバイス / 組織構築 / iPS由来心筋細胞 / 心筋細胞 / 心不全治療 / 間葉系幹細胞 / 重症心不全治療 / iPS心筋細胞 / ヒトiPS由来心筋 / 心筋組織 / 回転培養 Less
  • Research Projects

    (7 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (10 People)
  •  自発進行波を活用した成熟心筋組織由来の細胞外小胞を用いた虚血性心筋症の治療法開発Principal Investigator

    • Principal Investigator
      李 俊君
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      The University of Osaka
  •  Cardiac electrophysiology evaluation system for improved drug assessmentPrincipal Investigator

    • Principal Investigator
      李 俊君
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      Osaka University
  •  hiPSC Derived Mesenchymal stem cells Tissue Enhance Therapeutic Effects of Cardiomyocytes and MSC Tissue Transplantation in Myocardial Infarction Model

    • Principal Investigator
      劉 莉
    • Project Period (FY)
      2022 – 2024
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 55030:Cardiovascular surgery-related
    • Research Institution
      Osaka University
  •  Creating "3D mini heart" for transplantation of heart failure

    • Principal Investigator
      Sawa Yoshiki
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 55:Surgery of the organs maintaining homeostasis and related fields
    • Research Institution
      Osaka University
  •  マイクロ・ナノファイバー融合型デバイスを用いた「心神融合」新規培養法の開発

    • Principal Investigator
      藤本 七恵
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Challenging Research (Exploratory)
    • Review Section
      Medium-sized Section 20:Mechanical dynamics, robotics, and related fields
    • Research Institution
      Osaka University
  •  Novel method for treating myocardium infarction by using cardiac tissue ring matured by spontaneous traveling wavePrincipal Investigator

    • Principal Investigator
      LI JUNJUN
    • Project Period (FY)
      2019 – 2021
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 90120:Biomaterials-related
    • Research Institution
      Osaka University
  •  Circulating traveling wave enhances the maturation of cardiomyocytes in self-organized tissuePrincipal Investigator

    • Principal Investigator
      LI Junjun
    • Project Period (FY)
      2017 – 2018
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Intelligent mechanics/Mechanical systems
    • Research Institution
      Osaka University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation Patent

  • [Journal Article] ONO-1301 Enhances Post-transplantation Survival of Human Induced Pluripotent Stem Cell-derived Cardiac Tissue Sheet by Promoting Angiogenesis2023

    • Author(s)
      Xiang Qu, Junjun Li, Li Liu, Yoshiki Sakai, Jingbo Zhang, Ying Hua, Kota Suzuki, Akima Harada, Masako Ishida, Noriko Yoshida, Daisuke Okuzaki, Yoshiki Sawa, Shigeru Miyagawa
    • Journal Title

      The Journal of Heart and Lung Transplantation

      Volume: - Issue: 6 Pages: 716-716

    • DOI

      10.1016/j.healun.2023.01.018

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H00542, KAKENHI-PROJECT-23K24416, KAKENHI-PROJECT-23K27671
  • [Journal Article] Development of a thick and functional human adipose-derived stem cell tissue sheet for myocardial infarction repair in rat hearts.2023

    • Author(s)
      Jingbo Zhang, Junjun Li, Xiang Qu, Yuting Liu, Akima Harada, Ying Hua, Noriko Yoshida, Masako Ishida, Akiko Tabata, Lifu Sun, Li Liu, Shigeru Miyagawa
    • Journal Title

      Stem cell research & therapy

      Volume: 14 Issue: 1 Pages: 380-380

    • DOI

      10.1186/s13287-023-03560-9

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-23K24416
  • [Journal Article] Modeling Reduced Contractility and Stiffness Using iPSC-Derived Cardiomyocytes Generated From Female Becker Muscular Dystrophy Carrier2023

    • Author(s)
      Kameda Satoshi、Higo Shuichiro、Shiba Mikio、Kondo Takumi、Li Junjun、Liu Li、Tabata Tomoka、Inoue Hiroyuki、Okuno Shota、Ogawa Shou、Kuramoto Yuki、Yasutake Hideki、Lee Jong-Kook、Takashima Seiji、Ikeda Yoshihiko、Hikoso Shungo、Miyagawa Shigeru、Sakata Yasushi
    • Journal Title

      JACC: Basic to Translational Science

      Volume: - Issue: 6 Pages: 599-613

    • DOI

      10.1016/j.jacbts.2022.11.007

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K19526, KAKENHI-PROJECT-21H02915, KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-21H02914
  • [Journal Article] Developing Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction2023

    • Author(s)
      Junjun Li, Xiang Qu, Li Liu, Lingjun Li, Ying Hua, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Nagako Sougawa, Emiko Ito, Noriko Mochizuki-Oda, Akima Harada, Takuji Kawamura, Ryohei Matsuura, Yingzhe Wang, Keisuke Morishima, Shigeru Miyagawa, Yoshiki Sawa
    • Journal Title

      Advanced Fiber Materials

      Volume: 5 Issue: 6 Pages: 1905-1905

    • DOI

      10.1007/s42765-023-00313-4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K24416
  • [Journal Article] Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin2023

    • Author(s)
      Hitsumoto T, Tsukamoto O, Matsuoka K, Li J, Liu L, Kuramoto Y, Higo S, Ogawa S, Fujino N, Yoshida S, Kioka H, Kato H, Hakui H, Saito Y, Okamoto C, Inoue H, Hyejin J, Ueda K, Segawa T, Nishimura S, Asano Y, Asanuma H, Tani A, Imamura R, Komagawa S, Kanai T, Takamura M, Sakata Y, Kitakaze M, Haruta JI, Takashima S.
    • Journal Title

      Circulation

      Volume: - Issue: 25 Pages: 1902-1918

    • DOI

      10.1161/circulationaha.122.062885

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K07338, KAKENHI-PROJECT-23KJ1480, KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-21H02914, KAKENHI-PROJECT-20H03927, KAKENHI-PROJECT-23K24327
  • [Journal Article] Tissue Sheet Engineered Using Human Umbilical Cord-Derived Mesenchymal Stem Cells Improves Diabetic Wound Healing2022

    • Author(s)
      Zhang Jingbo、Qu Xiang、Li Junjun、Harada Akima、Hua Ying、Yoshida Noriko、Ishida Masako、Sawa Yoshiki、Liu Li、Miyagawa Shigeru
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 23 Issue: 20 Pages: 12697-12697

    • DOI

      10.3390/ijms232012697

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-20H00542, KAKENHI-PROJECT-23K24416
  • [Journal Article] Engineered Tissue for Cardiac Regeneration: Current Status and Future Perspectives2022

    • Author(s)
      Li Junjun、Liu Li、Zhang Jingbo、Qu Xiang、Kawamura Takuji、Miyagawa Shigeru、Sawa Yoshiki
    • Journal Title

      Bioengineering

      Volume: 9 Issue: 11 Pages: 605-605

    • DOI

      10.3390/bioengineering9110605

    • Data Source
      KAKENHI-PROJECT-22K12801, KAKENHI-PROJECT-20H00542
  • [Journal Article] Development and evaluation of a novel xeno-free culture medium for human-induced pluripotent stem cells2022

    • Author(s)
      Ying Hua, Kenji Yoshimochi, Junjun Li, Kazuhiro Takekita, Motoshi Shimotsuma, Lingjun Li, Xiang Qu, Jingbo Zhang, Yoshiki Sawa, Li Liu, Shigeru Miyagawa
    • Journal Title

      Stem Cell Research & Therapy

      Volume: 13 Issue: 1 Pages: 223-223

    • DOI

      10.1186/s13287-022-02879-z

    • Data Source
      KAKENHI-PROJECT-20H00542
  • [Journal Article] Therapeutic efficacy of large aligned cardiac tissue derived from induced pluripotent stem cell in a porcine ischemic cardiomyopathy model2021

    • Author(s)
      Suzuki Kota、Miyagawa Shigeru、Liu Li、Kawamura Takuji、Li Junjun、Qu Xiang、Harada Akima、Toda Koichi、Yoshioka Daisuke、Kainuma Satoshi、Kawamura Ai、Sawa Yoshiki
    • Journal Title

      The Journal of Heart and Lung Transplantation

      Volume: 40 Issue: 8 Pages: 767-777

    • DOI

      10.1016/j.healun.2021.04.010

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Journal Article] Circulating re-entrant waves promote maturation of hiPSC-derived cardiomyocytes in self-organized tissue ring2020

    • Author(s)
      Li Junjun、Zhang Lu、Yu Leqian、Minami Itsunari、Miyagawa Shigeru、H?rning Marcel、Dong Ji、Qiao Jing、Qu Xiang、Hua Ying、Fujimoto Nanae、Shiba Yuji、Zhao Yang、Tang Fuchou、Chen Yong、Sawa Yoshiki、Tang Chao、Liu Li
    • Journal Title

      Communications Biology

      Volume: 3 Issue: 1

    • DOI

      10.1038/s42003-020-0853-0

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Journal Article] hiPSC-Derived Cardiac Tissue for Disease Modeling and Drug Discovery2020

    • Author(s)
      Li Junjun、Hua Ying、Miyagawa Shigeru、Zhang Jingbo、Li Lingjun、Liu Li、Sawa Yoshiki
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 21 Issue: 23 Pages: 8893-8893

    • DOI

      10.3390/ijms21238893

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Journal Article] Clonal Isolation of Human Pluripotent Stem Cells on Nanofibrous Substrates Reveals an Advanced Sub-clone for Cardiomyocyte Differentiation2019

    • Author(s)
      Yu, L. ; Li, J. ; , Minami, I.; Qu X.; Miyagawa S.; Fujimoto, N.; Hasegawa K.; Chen, Y.; Sawa, Y.; Kotera, H.; Liu, L.,
    • Journal Title

      Advanced Healthcare Materials

      Volume: In press

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14624
  • [Journal Article] Low Cell-Matrix Adhesion Reveals Two Subtypes of Human Pluripotent Stem Cells.2018

    • Author(s)
      Yu, L.; Li, J.; Hong, J.; Takashima, Y.; Fujimoto, N.; Nakajima, M.; Yamamoto, A.; Dong, X.; Dang, Y.; Hou, Y.; Yang, W.; Minami, I.; Okita, K.; Tanaka, M.; Luo, C.; Tang, F.; Chen, Y.; Tang, C.; Kotera, H. & Liu, L.
    • Journal Title

      Stem Cell Reports

      Volume: 11 Issue: 1 Pages: 142-156

    • DOI

      10.1016/j.stemcr.2018.06.003

    • NAID

      120006488610

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H00855, KAKENHI-PROJECT-17K14624, KAKENHI-PROJECT-16H02465
  • [Patent] 細胞培養方法及びその装置2022

    • Inventor(s)
      劉莉 李俊君 澤芳樹 宮川繁など
    • Industrial Property Rights Holder
      劉莉 李俊君 澤芳樹 宮川繁など
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2022-038842
    • Filing Date
      2022
    • Data Source
      KAKENHI-PROJECT-20H00542
  • [Patent] 心筋細胞層の製造方法、心筋細胞層、およびその利用2021

    • Inventor(s)
      劉莉、澤芳樹、宮川繁、李俊君、武田真季、三好隼人
    • Industrial Property Rights Holder
      劉莉、澤芳樹、宮川繁、李俊君、武田真季、三好隼人
    • Industrial Property Rights Type
      特許
    • Filing Date
      2021
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Patent] Ring-like cardiac tissue construct2018

    • Inventor(s)
      Liu, L.; Li, J.
    • Industrial Property Rights Holder
      Liu, L.; Li, J.
    • Industrial Property Rights Type
      特許
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-17K14624
  • [Presentation] Developing Thick Cardiac Tissue with a Multilayer Fiber Sheet for Treating Myocardial Infarction2023

    • Author(s)
      劉 莉, 李 俊君, 曲 翔, 澤 芳樹
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-23K24416
  • [Presentation] ONO-1301 enhances survival of iPS cell-derived cardiac tissue sheet by promoting angiogenesis2023

    • Author(s)
      劉 莉, 李 俊君, 曲 翔, 澤 芳樹
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-23K24416
  • [Presentation] Human iPSC-derived closed-loop cardiac tissue for improved drug assessment2023

    • Author(s)
      Ying Hua, Junjun Li, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Hayato Miyoshi, Mikio Shiba3, Shuichiro Higo4,5, Nagako Sougawa1, Maki Takeda1, Takuji Kawamura1, Ryohei Matsuura, Toshihiko Toyofuku, Yoshiki Sawa, Li Liu and Shigeru Miyagawa
    • Organizer
      The 87th Annual Scientific Meeting of the Japanese Circulation Society (JCS2023)
    • Invited
    • Data Source
      KAKENHI-PROJECT-22K12801
  • [Presentation] Transplantation of matured hiPSC-derived Cardiac Cell Sheets for Myocardial Infraction Repair2022

    • Author(s)
      Ying Hua, Junjun Li, Xiang Qu, Jingbo Zhang, Noriko Yoshida, Masako Ishida, Yoshiki Sawa, Li Liu, Shigeru Miyagawa
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-23K24416
  • [Presentation] ONO-1301 Enhanced Survival of Transplanted hiPSC Derived Cardiomyocytes Tissue in a Rat MI Model2021

    • Author(s)
      Xiang Qu, Jingbo Zhang, Ying Hua, Junjun Li, Kota Suzuki, Akima Harada, Yoshiki Sakai, Liu Li, Yoshiki Sawa, Shigeru Miyagawa
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-20H00542
  • [Presentation] Human iPSC derived cardiac tissue matured by spontaneous traveling waves for improved drug assessment2021

    • Author(s)
      1.Li, J., Liu, L., Miyagawa, S., Kawamura, T., Matsuura, R., Hua, Y., Qu, X., Sougawa, N., Sawa, Y.,
    • Organizer
      American Heart Association Scientific Session, (2021)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Presentation] 配向性を持つ多層化心筋組織の作製2021

    • Author(s)
      依田崇典、劉莉、李俊君、笹井雅夫、植村壽公、森田健一、上村葉、小野貴弘、澤芳樹、宮川繁
    • Organizer
      日本再生医療学会
    • Data Source
      KAKENHI-PROJECT-20H00542
  • [Presentation] CIRCULATING TRAVELING WAVES ENHANCE THE MATURATION OF HIPSC-DERIVED CARDIOMYOCYTES IN SELF-ORGANIZED TISSUE RING2019

    • Author(s)
      Li Junjun
    • Organizer
      CiRA 2019 International Symposium
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Presentation] Circulating TRAVELING WAVES ENHANCE THE MATURATION OF HIPSC-DERIVED CARDIOMYOCYTES IN SELF-ORGANIZED TISSUE RING2019

    • Author(s)
      Li Junjun
    • Organizer
      The 8th Meeting of the International Federation for Artificial Organs
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K12801
  • [Presentation] Generating functional anisotropic and 3D tissue-like construct using induced pluripotent stem cell-derived cardiomyocytes.2017

    • Author(s)
      Li Junjun
    • Organizer
      Biomedical Engineering Society Annual Meeting
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K14624
  • 1.  Liu Li (50380093)
    # of Collaborated Projects: 4 results
    # of Collaborated Products: 14 results
  • 2.  Minami Itsunari (40362537)
    # of Collaborated Projects: 3 results
    # of Collaborated Products: 2 results
  • 3.  Sawa Yoshiki (00243220)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 4 results
  • 4.  藤本 七恵 (00838691)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  植村 寿公 (60176641)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 6.  宮川 繁 (70544237)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 7.  KATO Hisakazu
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  坂田 泰史
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  肥後 修一朗
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  田中 求
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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