Kotani Tetsuya 小谷哲也

Researcher Number	10724643
Affiliation (Current)	2025: 東京科学大学, 総合研究院, 特任講師
Affiliation (based on the past Project Information) *help	2025: 東京科学大学, 総合研究院, 特任講師 2023: 東京工業大学, 科学技術創成研究院, 特任助教 2019 – 2022: 東京工業大学, 生命理工学院, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 43030:Functional biochemistry-related
Keywords	Principal Investigator オートファゴソーム / オートファジー / 脂質 / 脂質輸送タンパク質 / 膜動態 / 隔離膜 / 膜形態 / リン酸化 / 出芽酵母 / 小胞体 / 酵母

オートファゴソーム形成における脂質供給反応の制御機構の解明Principal Investigator
- Principal Investigator
  
  小谷哲也
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Institute of Science Tokyo
オートファゴソーム形成における膜の形態制御機構の解明Principal Investigator
- Principal Investigator
  
  小谷哲也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Institute of Technology
Elucidation of membrane expansion mechanism in autophagosome formationPrincipal Investigator
- Principal Investigator
  
  Kotani Tetsuya
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43030:Functional biochemistry-related
- Research Institution
  Tokyo Institute of Technology

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Molecular Mechanism of Autophagy, Cytoplasmic Zoning by Lipid Membranes2023
- Author(s)
  Kotani Tetsuya、Yasuda Yuri、Nakatogawa Hitoshi
- Journal Title
  
  The Journal of Biochemistry
  
  Volume: 175 Issue: 2 Pages: 155-165
- DOI
  10.1093/jb/mvad099
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06123
[Journal Article] A mechanism that ensures non-selective cytoplasm degradation by autophagy2023
- Author(s)
  Kotani Tetsuya、Sakai Yuji、Kirisako Hiromi、Kakuta Chika、Kakuta Soichiro、Ohsumi Yoshinori、Nakatogawa Hitoshi
- Journal Title
  
  Nature Communications
  
  Volume: 14 Issue: 1 Pages: 5815-5815
- DOI
  10.1038/s41467-023-41525-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06123, KAKENHI-PROJECT-23K05715
[Journal Article] The Atg1 complex, Atg9, and Vac8 recruit PI3K complex I to the pre-autophagosomal structure2023
- Author(s)
  Hitomi Kanae、Kotani Tetsuya、Noda Nobuo N.、Kimura Yayoi、Nakatogawa Hitoshi
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 222 Issue: 8
- DOI
  10.1083/jcb.202210017
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06123, KAKENHI-PLANNED-19H05707
[Journal Article] Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus2022
- Author(s)
  Mochida Keisuke、Otani Toshifumi、Katsumata Yuto、Kirisako Hiromi、Kakuta Chika、Kotani Tetsuya、Nakatogawa Hitoshi
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 221 Issue: 2
- DOI
  10.1083/jcb.202103178
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H01430, KAKENHI-PROJECT-19K16071, KAKENHI-PLANNED-19H05708
[Journal Article] オートファゴソーム膜の供給②：小胞2020
- Author(s)
  小谷哲也、中戸川仁
- Journal Title
  
  週刊「医学のあゆみ」
  
  Volume: 272 Pages: 725-729
- Data Source
  KAKENHI-PROJECT-19K16071
[Journal Article] <i>N</i>-glycosylation of Rim21 at an Unconventional Site Fine-tunes Its Behavior in the Plasma Membrane2020
- Author(s)
  Obara K, Kotani T, Nakatogawa H, Kihara A, Kamura T
- Journal Title
  
  Cell Struct. Funct.
  
  Volume: 45 Issue: 1 Pages: 1-8
- DOI
  10.1247/csf.19021
- NAID
  130007784461
- ISSN
  0386-7196, 1347-3700
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K06561, KAKENHI-PROJECT-19K16071, KAKENHI-PUBLICLY-19H04957, KAKENHI-PLANNED-19H05708, KAKENHI-PROJECT-17H01430, KAKENHI-PROJECT-16K07288, KAKENHI-PROJECT-18K19292
[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020
- Author(s)
  Matoba Kazuaki、Kotani Tetsuya、Tsutsumi Akihisa、Tsuji Takuma、Mori Takaharu、Noshiro Daisuke、Sugita Yuji、Nomura Norimichi、Iwata So、Ohsumi Yoshinori、Fujimoto Toyoshi、Nakatogawa Hitoshi、Kikkawa Masahide、Noda Nobuo N.
- Journal Title
  
  Nature Structural & Molecular Biology
  
  Volume: 27 Issue: 12 Pages: 1185-1193
- DOI
  10.1038/s41594-020-00518-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K06532, KAKENHI-PROJECT-19K07265, KAKENHI-PROJECT-19K16071, KAKENHI-PROJECT-19K16344, KAKENHI-PLANNED-19H05707, KAKENHI-PUBLICLY-20H05339, KAKENHI-PROJECT-16H06375, KAKENHI-PROJECT-19H05645, KAKENHI-PROJECT-18H03989, KAKENHI-PROJECT-18H04023, KAKENHI-PROJECT-19H00923, KAKENHI-PROJECT-18K05334, KAKENHI-PROJECT-18K06097, KAKENHI-PLANNED-19H05708, KAKENHI-PLANNED-19H05777
[Journal Article] TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes2020
- Author(s)
  Tomioka Yui、Kotani Tetsuya、Kirisako Hiromi、Oikawa Yu、Kimura Yayoi、Hirano Hisashi、Ohsumi Yoshinori、Nakatogawa Hitoshi
- Journal Title
  
  Journal of Cell Biology
  
  Volume: 219 Issue: 7 Pages: 301-305
- DOI
  10.1083/jcb.201910063
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K16071, KAKENHI-PROJECT-16H06375, KAKENHI-PROJECT-17H01430, KAKENHI-PLANNED-19H05708, KAKENHI-PROJECT-19H03774
[Journal Article] The latest image of the mechanisms of autophagosome formation2019
- Author(s)
  中戸川仁、小谷哲也
- Journal Title
  
  生化学
  
  Volume: 91 Issue: 5 Pages: 602-610
- DOI
  10.14952/SEIKAGAKU.2019.910602
- ISSN
  0037-1017
- Year and Date
  2019-10-25
- Language
  Japanese
- Data Source
  KAKENHI-PROJECT-19K16071
[Presentation] Atg24複合体が伸張中の隔離膜の開口部の拡大を可能にしている2023
- Author(s)
  小谷哲也、境祐二、桐浴裕巳、角田千香、角田宗一郎、大隅良典、中戸川仁
- Organizer
  第15回オートファジー研究会　第5回新学術「マルチモードオートファジー」班会議　若手の会
- Data Source
  KAKENHI-PROJECT-22K06123
[Presentation] Atg24-Atg20 complex is necessary for sequestration of large components into autophagosome2022
- Author(s)
  Tetsuya Kotani, Hiromi Kirisako, Chika Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06123
[Presentation] Atg24-Atg20 complex is necessary for sequestration of large components into autophagosome2022
- Author(s)
  Tetsuya Kotani, Hiromi Kirisako, Chika Kakuta, Yoshinori Ohsumi, Hitoshi Nakatogawa
- Organizer
  The 10th International Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16071
[Presentation] オートファゴソーム形成における膜の形態制御2021
- Author(s)
  小谷哲也　中戸川仁
- Organizer
  第42回生体膜と薬物の相互作用シンポジウム
- Data Source
  KAKENHI-PROJECT-19K16071
[Presentation] マイトファジーに必要な隔離膜の形態制御機構2021
- Author(s)
  小谷哲也　中戸川仁
- Organizer
  第94回日本生化学会
- Data Source
  KAKENHI-PROJECT-19K16071
[Presentation] 隔離膜伸張におけるAtg24複合体の役割2019
- Author(s)
  小谷哲也
- Organizer
  第12回オートファジー研究会第1回新学術「マルチモードオートファジー」班会議
- Data Source
  KAKENHI-PROJECT-19K16071
[Presentation] The Atg2-Atg18 complex tethers pre-autophagosomal membranes to the endoplasmic reticulum2019
- Author(s)
  小谷哲也
- Organizer
  JSPS A3 Foresight Program The 5th Joint Symposium on Autophagy
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K16071

1. 森貴治

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 中戸川仁

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Kotani Tetsuya 小谷 哲也

Research Projects

Research Products

Co-Researchers

オートファゴソーム形成における脂質供給反応の制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

オートファゴソーム形成における膜の形態制御機構の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of membrane expansion mechanism in autophagosome formationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Molecular Mechanism of Autophagy, Cytoplasmic Zoning by Lipid Membranes2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A mechanism that ensures non-selective cytoplasm degradation by autophagy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Atg1 complex, Atg9, and Vac8 recruit PI3K complex I to the pre-autophagosomal structure2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Atg39 links and deforms the outer and inner nuclear membranes in selective autophagy of the nucleus2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] オートファゴソーム膜の供給②：小胞2020

Author(s)

Journal Title

Data Source

[Journal Article] <i>N</i>-glycosylation of Rim21 at an Unconventional Site Fine-tunes Its Behavior in the Plasma Membrane2020

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Atg9 is a lipid scramblase that mediates autophagosomal membrane expansion2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] TORC1 inactivation stimulates autophagy of nucleoporin and nuclear pore complexes2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The latest image of the mechanisms of autophagosome formation2019

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Presentation] Atg24複合体が伸張中の隔離膜の開口部の拡大を可能にしている2023

Author(s)

Organizer

Data Source

[Presentation] Atg24-Atg20 complex is necessary for sequestration of large components into autophagosome2022

Author(s)

Organizer

Data Source

Kotani Tetsuya 小谷哲也