MIKI AKIKO 三木明子

… Alternative Names

Miki Akiko 三木明子

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Researcher Number	10726988
Other IDs
Affiliation (Current)	2025: 神戸大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2023: 神戸大学, 医学部附属病院, 講師 2014 – 2023: 神戸大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology Except Principal Investigator Basic Section 56060:Ophthalmology-related / Ophthalmology
Keywords	Principal Investigator 細胞接着 / 眼細胞生物学 / 網膜色素上皮細胞 / 脈絡膜 / 網膜色素上皮 / 細胞間接着 / 網膜 / 細胞、組織 / 血管透過性 / タイトジャンクション / アドレノメデュリン … More Except Principal Investigator … More 網膜神経節細胞 / 糖尿病網膜症 / 乳酸 / アクアポリン / 緑内障 / 視神経脊髄炎 / 細胞間接着分子1 / Müller細胞 / 網膜血管内皮細胞 / 糖尿病黄斑浮腫 / ICAM-1 / フィブリノーゲン / モノカルボキシレート輸送体 / 視神経挫滅 / 外傷性視神経症 / モノカルボン酸輸送体 / アクアポリン９ / 暗所視閾値電位 / アストロサイト / 眼科学 / ゲノム / 感受性遺伝子 / ゲノムワイド関連解析 / 遺伝子多型 / 中心性漿液性脈絡網膜症 / アポトーシス / 難治視神経疾患 / アクアポリン４ / 光干渉断層計 / ヒト化免疫グロブリン Less

pachychoroid疾患の病態解明Principal Investigator
- Principal Investigator
  
  三木明子
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kobe University
Research for the pathophysiological investigation of diabetic macular edema focusing on fibrinogen accumulation in the retina.
- Principal Investigator
  
  Imai Hisanori
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kobe University
Pathogenesis of neuroretinal degeneration as an aquaporinopathy
- Principal Investigator
  
  Nakamura Makoto
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kobe University
Pathophysiology of serous retinal detachment in central serous chorioretinopathyPrincipal Investigator
- Principal Investigator
  
  Miki Akiko
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56060:Ophthalmology-related
- Research Institution
  Kobe University
Identification and clinical use of susceptibility gene of central serous chorioretinopathy
- Principal Investigator
  
  HONDA Shigeru
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Osaka City University
  Kobe University
The role of adrenomedullin in central serous chorioretinopathyPrincipal Investigator
- Principal Investigator
  
  Miki Akiko
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Ophthalmology
- Research Institution
  Kobe University
Role of aquaporin in retinal and optic nerve degenerative disorders
- Principal Investigator
  
  NAKAMURA Makoto
- Project Period (FY)
  2014 – 2016
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Ophthalmology
- Research Institution
  Kobe University

All 2023 2021 2020 2019 2018 2017 2016 2015 2014 Other

All Journal Article Presentation

[Journal Article] Removal of Sub-Internal Limiting Membrane Hemorrhage Secondary to Retinal Arterial Macroaneurysm Rupture: Internal Limiting Membrane Non-Peeling Technique2023
- Author(s)
  Kimura Akari、Imai Hisanori、Iwane Yukako、Kishimoto Maya、Sotani Yasuyuki、Yamada Hiroko、Matsumiya Wataru、Miki Akiko、Kusuhara Sentaro、Nakamura Makoto
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 9 Pages: 3291-3291
- DOI
  10.3390/jcm12093291
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09719
[Journal Article] Short-Term Outcomes of Intravitreal Faricimab Injection for Diabetic Macular Edema2023
- Author(s)
  Kusuhara Sentaro、Kishimoto-Kishi Maya、Matsumiya Wataru、Miki Akiko、Imai Hisanori、Nakamura Makoto
- Journal Title
  
  Medicina
  
  Volume: 59 Issue: 4 Pages: 665-665
- DOI
  10.3390/medicina59040665
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09766, KAKENHI-PROJECT-21K09719
[Journal Article] Cystotomy with or without fibrinogen clot removal for refractory cystoid macular edema secondary to branch retinal vein occlusion2021
- Author(s)
  Yamada Hiroko、Imai Hisanori、Tetsumoto Akira、Hayashida Mayuka、Otsuka Keiko、Miki Akiko、Kusuhara Sentaro、Nakamura Makoto
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 8460-8460
- DOI
  10.1038/s41598-021-88149-z
- NAID
  120007038635
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09719
[Journal Article] The long-term effect of cystotomy with fibrinogen clot removal for a cystoid macular edema secondary to idiopathic macular telangiectasia type 12021
- Author(s)
  Maki Hitomi、Imai Hisanori、Yamada Hiroko、Tetsumoto Akira、Hayashida Mayuka、Otsuka Keiko、Miki Akiko、Nakamura Makoto
- Journal Title
  
  RETINAL Cases & Brief Reports
  
  Volume: Publish Ahead of Print Issue: 2 Pages: 101-104
- DOI
  10.1097/icb.0000000000001117
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K09719
[Journal Article] En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabetic retina2020
- Author(s)
  Katsuyama Atsuko、Kusuhara Sentaro、Asahara Shun-Ichiro、Nakai Shun-Ichiro、Mori Sotaro、Matsumiya Wataru、Miki Akiko、Kurimoto Takuji、Imai Hisanori、Kido Yoshiaki、Ogawa Wataru、Nakamura Makoto
- Journal Title
  
  BMJ Open Diabetes Research & Care
  
  Volume: 8 Issue: 1 Pages: e001120-e001120
- DOI
  10.1136/bmjdrc-2019-001120
- NAID
  120006863549
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09409, KAKENHI-PROJECT-18K09447, KAKENHI-PROJECT-18KK0438, KAKENHI-PROJECT-17H01966, KAKENHI-PROJECT-17K09882
[Journal Article] Aqp9 Gene Deletion Enhances Retinal Ganglion Cell (RGC) Death and Dysfunction Induced by Optic Nerve Crush: Evidence that Aquaporin 9 Acts as an Astrocyte-to-Neuron Lactate Shuttle in Concert with Monocarboxylate Transporters To Support RGC Function and Survival2020
- Author(s)
  Mori Sotaro、Kurimoto Takuji、Miki Akiko、Maeda Hidetaka、Kusuhara Sentaro、Nakamura Makoto
- Journal Title
  
  Molecular Neurobiology
  
  Volume: 57 Issue: 11 Pages: 4530-4548
- DOI
  10.1007/s12035-020-02030-0
- NAID
  120006892075
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09447
[Journal Article] Genome-wide association study to identify a new susceptibility locus for central serous chorioretinopathy in the Japanese population.2018
- Author(s)
  Miki A, Sakurada Y, Tanaka K, Semba K, Mitamura Y, Yuzawa M, Tajima A, Nakatochi M, Yamamoto K, Matsuo K, Imoto I, Honda S.
- Journal Title
  
  Invest Ophthalmol Vis Sci.
  
  Volume: 59(13) Issue: 13 Pages: 5542-5547
- DOI
  10.1167/iovs.18-25497
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-26108007, KAKENHI-PROJECT-16K11286, KAKENHI-PROJECT-17K16971, KAKENHI-PROJECT-16H06277, KAKENHI-PROJECT-18H02894
[Journal Article] Polypoidal Choroidal Vasculopathy Associated with Optic Disc Coloboma2018
- Author(s)
  Nakano Yumiko、Miki Akiko、Honda Shigeru、Nakamura Makoto
- Journal Title
  
  Case Reports in Ophthalmology
  
  Volume: 9 Issue: 1 Pages: 98-101
- DOI
  10.1159/000485966
- NAID
  120006473638
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] Foveal Depression and Related Factors in Patients with a History of Retinopathy of Prematurity2018
- Author(s)
  Miki Akiko、Honda Shigeru、Inoue Yukako、Yamada Yuko、Nakamura Makoto
- Journal Title
  
  Ophthalmologica
  
  Volume: 240 Issue: 2 Pages: 106-110
- DOI
  10.1159/000488368
- NAID
  120006649607
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] The 24-month outcomes of intravitreal aflibercept combined with photodynamic therapy for polypoidal choroidal vasculopathy2018
- Author(s)
  Nakai Shunichiro、Matsumiya Wataru、Keiko Otsuka、Miki Akiko、Nakamura Makoto、Honda Shigeru
- Journal Title
  
  Japanese Journal of Ophthalmology
  
  Volume: 63 Issue: 1 Pages: 100-108
- DOI
  10.1007/s10384-018-0636-z
- NAID
  210000168959
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] Comparison of the 12-Month Outcomes of Intravitreal Ranibizumab between Two Angiographic Subtypes of Polypoidal Choroidal Vasculopathy.2017
- Author(s)
  Nakai S, Honda S, Matsumiya W, Miki A, Nakamura M.
- Journal Title
  
  Molecular Vision
  
  Volume: 237 Pages: 123-127
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] PDT併用bevacizumab硝子体注射により長期的視力改善を認めた脈絡膜骨腫続発脈絡膜血管新生の1例2017
- Author(s)
  榎本寛子、本田茂、三木明子、大塚慶子、中井駿一朗、今井尚徳、楠原仙太郎、中村誠
- Journal Title
  
  臨床眼科
  
  Volume: 71 Pages: 1505-1511
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] Retreatment of Exudative Age-Related Macular Degeneration after Loading 3-Monthly Intravitreal Ranibizumab2017
- Author(s)
  Sugiyama Atsushi、Sakurada Yoichi、Honda Shigeru、Miki Akiko、Matsumiya Wataru、Yoneyama Seigo、Kikushima Wataru、Iijima Hiroyuki
- Journal Title
  
  Ophthalmologica
  
  Volume: 239 Issue: 1 Pages: 52-59
- DOI
  10.1159/000480439
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] 糖尿病黄斑浮腫に対するRanibizumab単会投与後の経過に関する検討2017
- Author(s)
  藤井誠士郎、本田茂、大塚慶子、三木明子、今井尚徳、楠原仙太郎、中村誠
- Journal Title
  
  あたらしい眼科
  
  Volume: 34 Pages: 280-282
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] Choroidal thickness of central serous chorioretinopathy secondary to corticosteroid use.2017
- Author(s)
  Honda S, Miki A, Kusuhara S, Imai H, Nakamura M.
- Journal Title
  
  Retina
  
  Volume: 印刷中 Issue: 8 Pages: 1562-1567
- DOI
  10.1097/iae.0000000000001380
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-16K11286
[Journal Article] Comparison of the 12-Month Outcomes of Intravitreal Ranibizumab between Two Angiographic Subtypes of Polypoidal Choroidal Vasculopathy.2017
- Author(s)
  Nakai, S., Honda, S., Miki, A., Matsumiya, W., Nakamura, M.
- Journal Title
  
  10.1159/000455273
  
  Volume: 237 Issue: 3 Pages: 123-127
- DOI
  10.1159/000455273
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-26861449, KAKENHI-PROJECT-16K11286
[Journal Article] Aquaporin 9 expression is required for l-lactate to maintain retinal neuronal survival2015
- Author(s)
  Akashi A, Miki A, Kanamori A, Nakamura M
- Journal Title
  
  Neurosci Lett.
  
  Volume: 589 Pages: 185-90
- DOI
  10.1016/j.neulet.2015.01.063
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462715, KAKENHI-PROJECT-26462661
[Journal Article] The expression of syntaphilin is down-regulated in the optic nerve after axonal injury2014
- Author(s)
  Miki A, Kanamori A, Nakamura M, Matsumoto Y, Mizokami J, Negi A
- Journal Title
  
  Exp Eye Res
  
  Volume: 129 Pages: 38-47
- DOI
  10.1016/j.exer.2014.10.017
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-25462715, KAKENHI-PROJECT-26462661
[Presentation] 難治性糖尿病黄斑浮腫に対する嚢胞様腔内壁切開術の長期経過の検討2023
- Author(s)
  山田裕子、今井尚徳、曽谷育之、岸真椰、平野真由香、大塚慶子、三木明子、中村誠
- Organizer
  第29回日本糖尿病眼学会総会
- Data Source
  KAKENHI-PROJECT-21K09719
[Presentation] 視神経挫滅後のアクアポリン9ノックアウトマウスにおける網膜神経節細胞の機能低下と乳酸輸送障害の関係2020
- Author(s)
  盛　崇太朗、栗本　拓治、三木　明子、前田　秀高、楠原仙太郎、中村　誠
- Organizer
  第68回日本臨床視覚電気生理学会
- Data Source
  KAKENHI-PROJECT-18K09447
[Presentation] Deletion of Aqp9 in mice enhances retinal ganglion cell death after optic nerve injury2019
- Author(s)
  Mori S, Kurimoto T, Miki A, Kusuhara S, Nakamura M
- Organizer
  The association for reseach in vision and ophthalmology 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K09447
[Presentation] アクアポリン9遺伝子欠損マウスにおける視神経挫滅後の網膜神経細胞死2018
- Author(s)
  盛崇太朗、栗本拓治、三木明子、楠原仙太郎、中村　誠
- Organizer
  第122回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-18K09447
[Presentation] 9.ポリープ状脈絡膜血管症に対するaflibercept併用光線力学療法の2年経過2017
- Author(s)
  中井駿一朗, 本田茂, 松宮亘, 三木明子, 大塚慶子, 近藤陽子, 中村誠
- Organizer
  第121回日本眼科学会総会
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] 12.Association between CFH variants and choroidal thickness in central serous chorioretinopathy.2017
- Author(s)
  Miki A, Honda S, Sakurada Y, Tanaka K, Hayashida M, Mitamura Y, Nakamura M.
- Organizer
  The Association for Research in Vision and Ophthalmology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] 2.視力良好なポリープ状脈絡膜血管症への光線力学的療法単独とアフリベルセプト併用療法2017
- Author(s)
  松宮亘、本田茂、中井駿一郎、勝山敦子、大塚慶子、三木明子、楠原仙太郎、中村誠
- Organizer
  第56回日本網膜硝子体学会総会
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] 4.視力良好なポリープ状脈絡膜血管症に対するaflibercept併用光線力学療法1年経過2017
- Author(s)
  中井駿一郎、本田茂、松宮亘、林田真由香、大塚慶子、三木明子、近藤陽子、中村誠
- Organizer
  第71回日本臨床眼科学会
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] 1.ポリープ状脈絡膜血管症へのaflibercept併用光線力学的療法とARMS2多型の関連性の検討2017
- Author(s)
  中井駿一郎、本田茂、松宮亘、林田真由香、大塚慶子、三木明子、近藤陽子、中村誠
- Organizer
  第56回日本網膜硝子体学会総会
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] 中心性漿液性脈絡網膜症における脈絡膜厚と補体H因子遺伝子多型の関連解析2016
- Author(s)
  三木明子, 本田茂,　櫻田　庸一, 田中　公二、　三田村　佳典, 中村誠
- Organizer
  第120回日本眼科学会総会
- Place of Presentation
  仙台
- Year and Date
  2016-04-07
- Data Source
  KAKENHI-PROJECT-16K11286
[Presentation] アクアポリン9は乳酸輸送を介して網膜神経節細胞の生存を制御する
- Author(s)
  明石梓、三木明子、井上結香子、金森章泰、中西裕子、中村　誠
- Organizer
  第25回日本緑内障学会
- Place of Presentation
  大阪国際会議場
- Year and Date
  2014-09-20 – 2014-09-22
- Data Source
  KAKENHI-PROJECT-26462661

1. NAKAMURA Makoto (80273788)

# of Collaborated Projects: 2 results

# of Collaborated Products: 5 results
2. HONDA Shigeru (60283892)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
3. Imai Hisanori (90569211)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 山田裕子 (00359861)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
5. 金森章泰 (10444572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 松宮亘 (30707120)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
7. 楠原仙太郎 (40437463)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
8. 栗本拓治 (50388815)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
9. IMOTO issei

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. MITAMURA yoshinori

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
11. SAKURADA yoichi

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
12. Nakai Shunichiro

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. Kitamura Megumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 橘逸勢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
15. 淺原俊一郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
16. 根木昭

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

MIKI AKIKO 三木 明子

Miki Akiko 三木 明子

Research Projects

Research Products

Co-Researchers

pachychoroid疾患の病態解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Research for the pathophysiological investigation of diabetic macular edema focusing on fibrinogen accumulation in the retina.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathogenesis of neuroretinal degeneration as an aquaporinopathy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Pathophysiology of serous retinal detachment in central serous chorioretinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification and clinical use of susceptibility gene of central serous chorioretinopathy

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

The role of adrenomedullin in central serous chorioretinopathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Role of aquaporin in retinal and optic nerve degenerative disorders

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Removal of Sub-Internal Limiting Membrane Hemorrhage Secondary to Retinal Arterial Macroaneurysm Rupture: Internal Limiting Membrane Non-Peeling Technique2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short-Term Outcomes of Intravitreal Faricimab Injection for Diabetic Macular Edema2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cystotomy with or without fibrinogen clot removal for refractory cystoid macular edema secondary to branch retinal vein occlusion2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] The long-term effect of cystotomy with fibrinogen clot removal for a cystoid macular edema secondary to idiopathic macular telangiectasia type 12021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] En face slab optical coherence tomography imaging successfully monitors progressive degenerative changes in the innermost layer of the diabetic retina2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Aqp9 Gene Deletion Enhances Retinal Ganglion Cell (RGC) Death and Dysfunction Induced by Optic Nerve Crush: Evidence that Aquaporin 9 Acts as an Astrocyte-to-Neuron Lactate Shuttle in Concert with Monocarboxylate Transporters To Support RGC Function and Survival2020

Author(s)

Journal Title

DOI

NAID

Data Source

MIKI AKIKO 三木明子

Miki Akiko 三木明子