Maruhashi Tatsuya 丸橋達也

Researcher Number	10727069
Other IDs
Affiliation (Current)	2025: 広島大学, 原爆放射線医科学研究所, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 広島大学, 原爆放射線医科学研究所, 准教授 2019: 広島大学, 病院(医), 助教 2016 – 2017: 広島大学, 病院(医), 医科診療医
Review Section/Research Field	Principal Investigator Basic Section 53020:Cardiology-related / Cardiovascular medicine Except Principal Investigator Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 血管内皮機能 / 時計遺伝子 / LKB1 / AMPK / 内皮型NO合成酵素 / DEC1 / 下肢閉塞性動脈硬化症 / 虚血性血管新生 / 間歇的圧迫 / 血管新生 … More Except Principal Investigator … More 新規血管内皮機能改善薬 / ヒト血管内皮機能 / 内皮型一酸化窒素合成酵素 / 血管内皮機能 / 新規レジスチン様分子 / 下肢虚血 / 血管新生 / 下肢閉塞性動脈硬化症 / 閉塞性動脈硬化症 / ミトコンドリア / 自家移植 / 心筋再生 / 心不全 Less

内皮型NO合成酵素制御および血管内皮機能調整における時計遺伝子DEC1の役割Principal Investigator
- Principal Investigator
  
  丸橋達也
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hiroshima University
elucidation of endothelial nitric oxide synthase regulation mechanism by a novel resistin-like molecule, relm beta, and its relationship to atherosclerosis
- Principal Investigator
  
  東幸仁
- Project Period (FY)
  2022 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hiroshima University
Autologous Mitochondrial Transplantation Rescues Critical Limb Ischemia
- Principal Investigator
  
  Kihara Yasuki
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hiroshima University
Role of a clock gene DEC1 in the regulation of endothelial NO synthasePrincipal Investigator
- Principal Investigator
  
  Maruhashi Tatsuya
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Hiroshima University
Effect of intermittent compression in a mouse hindlimb ischemia modelPrincipal Investigator
- Principal Investigator
  
  Maruhashi Tatsuya
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Hiroshima University

All 2023 2022 2020

All Journal Article Presentation

[Journal Article] Therapeutic myogenesis induced by ultrasound exposure in a volumetric skeletal muscle loss injury model.2023
- Author(s)
  Yusoff FM, Nakashima A, Kajikawa M, Maruhashi T, Kishimoto S, Higashi Y.
- Journal Title
  
  Am J Sports Med
  
  Volume: 51 Issue: 13 Pages: 3554-3554
- DOI
  10.1177/03635465231195850
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors2023
- Author(s)
  Kishimoto Shinji、Oda Nozomu、Maruhashi Tatsuya、Tanigawa Shunsuke、Mizobuchi Aya、Yusoff Farina Mohamad、Fujita Asuka、Uchiki Toshio、Kajikawa Masato、Yoshimura Kenichi、Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Nakano Yukiko、Hirota Seiko、Yoshinaga Shinji、Goto Chikara、Nakashima Ayumu、Higashi Yukihito
- Journal Title
  
  Frontiers in Cardiovascular Medicine
  
  Volume: 10 Pages: 1122794-1122794
- DOI
  10.3389/fcvm.2023.1122794
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] Is carotid arterial stiffness a therapeutic target of statin therapy?2023
- Author(s)
  Maruhashi T, Higashi Y
- Journal Title
  
  Hypertens Res
  
  Volume: 46 Issue: 3 Pages: 768-768
- DOI
  10.1038/s41440-022-01152-3
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Impact of overnight 1 mg dexamethasone on vascular function in patients with nonfunctioning adrenal adenomas.2023
- Author(s)
  Kishimoto S, Maruhashi T, Kajikawa M, Mizobuchi A, Yamaji T, Harada T, Nakano Y, Goto C, Yusoff FM, Nakashima A, Higashi Y.
- Journal Title
  
  Sci Rep.
  
  Volume: 13 Issue: 1 Pages: 20975-20975
- DOI
  10.1038/s41598-023-48295-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma2023
- Author(s)
  Kishimoto Shinji、Oki Kenji、Maruhashi Tatsuya、Kajikawa Masato、Mizobuchi Aya、Harada Takahiro、Yamaji Takayuki、Hashimoto Yu、Yoshimura Kenichi、Nakano Yukiko、Goto Chikara、Yusoff Farina Mohamad、Nakashima Ayumu、Higashi Yukihito
- Journal Title
  
  Hypertension Research
  
  Volume: 46 Issue: 9 Pages: 2213-2227
- DOI
  10.1038/s41440-023-01375-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K15131, KAKENHI-PROJECT-23K24329
[Journal Article] Current topic of vascular function in hypertension2023
- Author(s)
  Maruhashi T, Higashi Y
- Journal Title
  
  Hypertens Res
  
  Volume: 46 Issue: 3 Pages: 630-630
- DOI
  10.1038/s41440-022-01147-0
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Significant Correlates of Nocturnal Hypertension in Patients With Hypertension Who Are Treated With Antihypertensive Drugs2023
- Author(s)
  Maruhashi Tatsuya,Kinoshita Yoshihiko,Ozono Ryoji,Nakamaru Mitsuaki,Ninomiya Masanori,Oiwa Jiro,Kawagoe Takuji,Yoshida Osamu,Matsumoto Toshiyuki,Fukunaga Yasuo,Sumii Kotaro,Ueda Hironori,Shiode Nobuo,Takahari Kosuke,Hayashi Yasuhiko,Ono Yujiro,Nakano Yukiko,Takahashi Masakazu,Kihara Yasuki,Higashi Yukihito
- Journal Title
  
  American Journal of Hypertension
  
  Volume: 36 Issue: 6 Pages: 287-296
- DOI
  10.1093/ajh/hpad014
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K11995, KAKENHI-PROJECT-23K24329
[Journal Article] Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy2023
- Author(s)
  Hashimoto Y, Yamaji T, Kitagawa T, Nakano Y, Kajikawa M, Yoshimura K, Chayama K, Goto C, Tanigawa S, Mizobuchi A, Harada T, Yusoff FM, Kishimoto S, Maruhashi T, Fujita A, Uchiki T, Nakashima A, Higashi Y
- Journal Title
  
  J Clin Med
  
  Volume: 12 Issue: 7 Pages: 2534-2534
- DOI
  10.3390/jcm12072534
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Effect of ipragliflozin on endothelial dysfunction in patients with type 2 diabetes and chronic kidney disease: a randomized clinical trial (PROCEED).2023
- Author(s)
  Tanaka A, Okada Y, Torimoto K, Kamei N, Hirai H, Kono H, Sugimoto K, Teragawa H, Taguchi I, Maruhashi T, Sonoda S, Kurozumi A, Inagaki S, Oshita C, Hisauchi I, Takahashi K, Higashi Y, Shimabukuro M, Node K, on behalf of the PROCEED trial investigators.
- Journal Title
  
  Diabetes Metab
  
  Volume: 49 Issue: 4 Pages: 101447-101447
- DOI
  10.1016/j.diabet.2023.101447
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation2022
- Author(s)
  Yamaji T, Harada T, Hashimoto Y, Nakano Y, Kajikawa M, Yoshimura K, Chayama K, Goto C, Han Y, Mizobuchi A, Yusoff FM, Kishimoto S, Maruhashi T, Nakashima A, Higashi Y.
- Journal Title
  
  Sci Rep
  
  Volume: 12(1) Issue: 1 Pages: 6366-6366
- DOI
  10.1038/s41598-022-10242-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] The prevalence of cardiovascular disease is higher in patients with bilateral low ankle-brachial index than in patients with unilateral low ankle-brachial index2022
- Author(s)
  Maruhashi Tatsuya、Kajikawa Masato、Kishimoto Shinji、Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Mizobuchi Aya、Tanigawa Shunsuke、Yusoff Farina Mohamad、Nakano Yukiko、Chayama Kazuaki、Nakashima Ayumu、Goto Chikara、Yoshimura Kenichi、Higashi Yukihito
- Journal Title
  
  Atherosclerosis
  
  Volume: 360 Pages: 8-14
- DOI
  10.1016/j.atherosclerosis.2022.09.012
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] Implantation of Hypoxia-Induced Mesenchymal Stem Cell Advances Therapeutic Angiogenesis2022
- Author(s)
  Yusoff FM, Nakashima A, Kawano KI, Kajikawa M, Kishimoto S, Maruhashi T, Ishiuchi N, Abdul Wahid SFS, Higashi Y.
- Journal Title
  
  Stem Cells Int
  
  Volume: - Pages: 6795274-6795274
- DOI
  10.1155/2022/6795274
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] Isolated diastolic hypertension is not associated with endothelial dysfunction2022
- Author(s)
  Han Y, Maruhashi T, Kajikawa M, Kishimoto S, Yamaji T, Harada T, Hashimoto Y, Yusoff FM, Nakano Y, Chayama K, Nakashima A, Goto C, Yoshimura K, Higashi Y.
- Journal Title
  
  Hypertens ResInt
  
  Volume: 45(4) Issue: 4 Pages: 698-707
- DOI
  10.1038/s41440-022-00854-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
[Journal Article] White blood cell count is not associated with flow-mediated vasodilation or nitroglycerine-induced vasodilation2022
- Author(s)
  Kishimoto Shinji、Maruhashi Tatsuya、Kajikawa Masato、Harada Takahiro、Yamaji Takayuki、Han Yiming、Mizobuchi Aya、Hashimoto Yu、Yoshimura Kenichi、Nakano Yukiko、Chayama Kazuaki、Goto Chikara、Yusoff Farina Mohamad、Nakashima Ayumu、Higashi Yukihito
- Journal Title
  
  Scientific Reports
  
  Volume: 12 Issue: 1 Pages: 8201-8201
- DOI
  10.1038/s41598-022-12205-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] Long-Term Effect of Febuxostat on Endothelial Function in Patients With Asymptomatic Hyperuricemia: A Sub-Analysis of the PRIZE Study2022
- Author(s)
  Maruhashi T, Higashi Y, Yoshida H, Tanaka A, Eguchi K, Tomiyama H, Kario K, Kato T, Oda N, Tahara N, Oguri M, Watada H, Node K
- Journal Title
  
  Front Cardiovasc Med
  
  Volume: 9 Pages: 882821-882821
- DOI
  10.3389/fcvm.2022.882821
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function2022
- Author(s)
  Maruhashi T, Kajikawa M, Kishimoto S, Takaeko Y, Yamaji T, Harada T, Hashimoto Y, Han Y, Aibara Y, Yusoff FM, Nakano Y, Chayama K, Nakashima A, Goto C, Yoshimura K, Higashi Y.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis
  
  Volume: 29 Issue: 11 Pages: 1588-1602
- DOI
  10.5551/jat.63285
- NAID
  130008132408
- ISSN
  1340-3478, 1880-3873
- Year and Date
  2022-11-01
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
[Journal Article] Temporal Changes in Sparing and Enhancing Dose Protraction Effects of Ionizing Irradiation for Aortic Damage in Wild-Type Mice2022
- Author(s)
  Hamada N, Kawano KI, Nomura T, Furukawa K, Yusoff FM, Maruhashi T, Maeda M, Nakashima A, Higashi Y
- Journal Title
  
  Cancers
  
  Volume: 14 Issue: 14 Pages: 3319-3319
- DOI
  10.3390/cancers14143319
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Cardiovascular risk in patients receiving antihypertensive drug treatment from the perspective of endothelial function2022
- Author(s)
  Maruhashi T, Higashi Y
- Journal Title
  
  Hypertens Res
  
  Volume: 45 Issue: 8 Pages: 1322-1333
- DOI
  10.1038/s41440-022-00936-x
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K24329
[Journal Article] Relationship of Daily Coffee Intake with Vascular Function in Patients with Hypertension2022
- Author(s)
  Yamaji Takayuki、Harada Takahiro、Hashimoto Yu、Nakano Yukiko、Kajikawa Masato、Yoshimura Kenichi、Goto Chikara、Mizobuchi Aya、Tanigawa Shunsuke、Yusoff Farina Mohamad、Kishimoto Shinji、Maruhashi Tatsuya、Nakashima Ayumu、Higashi Yukihito
- Journal Title
  
  Nutrients
  
  Volume: 14 Issue: 13 Pages: 2719-2719
- DOI
  10.3390/nu14132719
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17083, KAKENHI-PROJECT-23K24329
[Journal Article] Relationship between hemoglobin A1c level and flow-mediated vasodilation in patients with type 2 diabetes mellitus receiving antidiabetic drugs2022
- Author(s)
  Yamaji T, Harada T, Hashimoto Y, Nakano Y, Kajikawa M, Yoshimura K, Aoki G, Chayama K, Goto C, Mizobuchi A, Han Y, Yusoff FM, Kishimoto S, Maruhashi T, Nakashima A, Higashi Y.
- Journal Title
  
  J Diabetes Investig
  
  Volume: 13(4) Issue: 4 Pages: 677-686
- DOI
  10.1111/jdi.13705
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17599, KAKENHI-PROJECT-23K24329
[Journal Article] Upstroke Time Is a Useful Vascular Marker for Detecting Patients With Coronary Artery Disease Among Subjects With Normal Ankle-Brachial Index2020
- Author(s)
  Tatsuya Maruhashi, Yukihito Higashi, Yasuki Kihara, et al.
- Journal Title
  
  J Am Heart Assoc .
  
  Volume: 9 Issue: 23
- DOI
  10.1161/jaha.120.017139
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08404
[Journal Article] Vascular function is further impaired in subjects aged 80 years or older2020
- Author(s)
  Tatsuya Maruhashi, Yukihito Higashi, Yasuki Kihara, et al.
- Journal Title
  
  Hypertens Res
  
  Volume: 43 Issue: 9 Pages: 914-921
- DOI
  10.1038/s41440-020-0435-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K08404, KAKENHI-PROJECT-18K09758
[Presentation] 血流依存性血管拡張反応とニトログリセリン誘発性血管拡張反応2020
- Author(s)
  丸橋達也、木原康樹、東幸仁
- Organizer
  第5回血管不全学会学術集会・総会
- Invited
- Data Source
  KAKENHI-PROJECT-20K08404

1. 東幸仁 (40346490)

# of Collaborated Projects: 4 results

# of Collaborated Products: 12 results
2. 中島歩 (40448262)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. Kihara Yasuki (40214853)

# of Collaborated Projects: 2 results

# of Collaborated Products: 3 results
4. 岸本真治 (30820667)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. NOMA Kensuke

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 梶川正人

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
7. 高橋雅和

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maruhashi Tatsuya 丸橋 達也

Research Projects

Research Products

Co-Researchers

内皮型NO合成酵素制御および血管内皮機能調整における時計遺伝子DEC1の役割Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

elucidation of endothelial nitric oxide synthase regulation mechanism by a novel resistin-like molecule, relm beta, and its relationship to atherosclerosis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autologous Mitochondrial Transplantation Rescues Critical Limb Ischemia

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Role of a clock gene DEC1 in the regulation of endothelial NO synthasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Effect of intermittent compression in a mouse hindlimb ischemia modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Therapeutic myogenesis induced by ultrasound exposure in a volumetric skeletal muscle loss injury model.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of exposure to radiation caused by an atomic bomb on endothelial function in atomic bomb survivors2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Is carotid arterial stiffness a therapeutic target of statin therapy?2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Impact of overnight 1 mg dexamethasone on vascular function in patients with nonfunctioning adrenal adenomas.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] KCNJ5 mutation is a predictor for recovery of endothelial function after adrenalectomy in patients with aldosterone-producing adenoma2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Current topic of vascular function in hypertension2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Significant Correlates of Nocturnal Hypertension in Patients With Hypertension Who Are Treated With Antihypertensive Drugs2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Endothelial Function Is Preserved in Patients with Wild-Type Transthyretin Amyloid Cardiomyopathy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effect of ipragliflozin on endothelial dysfunction in patients with type 2 diabetes and chronic kidney disease: a randomized clinical trial (PROCEED).2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Self-reported total sitting time on a non-working day is associated with blunted flow-mediated vasodilation and blunted nitroglycerine-induced vasodilation2022

Maruhashi Tatsuya 丸橋達也