Namba Takushi 難波卓司

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Takushi Namba 難波卓司

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Researcher Number	10729859
Other IDs
Affiliation (Current)	2025: 高知大学, 教育研究部総合科学系複合領域科学部門, 准教授
Affiliation (based on the past Project Information) *help	2024: 高知大学, 教育研究部総合科学系複合領域科学部門, 准教授 2016 – 2021: 高知大学, 教育研究部総合科学系複合領域科学部門, 准教授 2015: 高知大学, 教育研究部総合科学系複合領域科学部門, 特任助教 2014: 高知大学, 教育研究部総合科学系, 特任助教
Review Section/Research Field	Principal Investigator Biological pharmacy / Basic Section 40040:Aquatic life science-related / Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
Keywords	Principal Investigator 小胞体 / シグナル伝達 / ミトコンドリア / オートファジー / 癌 / 養殖技術 / ゲノム解析 / アオノリ / 小胞体-ミトコンドリア接触領域 / オルガネラコミュニケーション … More / アポトーシス / 小胞ストレス / IRE1 / p53 Less

ゲノム解析から解き明かす共生細菌によるミナミアオノリの成長促進作用の解明Principal Investigator
- Principal Investigator
  
  難波卓司
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 40040:Aquatic life science-related
- Research Institution
  Kochi University
Mitochondrial function regulated by the endoplasmic reticulum membrane protein BAP31 is associated with neurological disorders.Principal Investigator
- Principal Investigator
  
  Namba Takushi
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47030:Pharmaceutical hygiene and biochemistry-related
- Research Institution
  Kochi University
To identify new tummor suppressive factor, which regulates autophagy and apoptosis.Principal Investigator
- Principal Investigator
  
  Namba Takushi
- Project Period (FY)
  2016 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Biological pharmacy
- Research Institution
  Kochi University
Analysis of p53 new function for protein synthesis and identification of new anti-cancer targetPrincipal Investigator
- Principal Investigator
  
  Takushi Namba
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Biological pharmacy
- Research Institution
  Kochi University

All 2021 2020 2019 2018 2017 2015 Other

All Journal Article Presentation Book Patent

[Book] ミトコンドリアダイナミクス2021
- Author(s)
  石原直忠ほか　82名　難波卓司(p35-40)
- Total Pages
  458
- Publisher
  エヌ・ティー・エス
- ISBN
  9784860437466
- Data Source
  KAKENHI-PROJECT-19K07045
[Journal Article] Lavencidin, a polyene macrolide antibiotic from Streptomyces lavendulae FRI-52021
- Author(s)
  Yoshioka Takuya、Igarashi Yasuhiro、Namba Takushi、Ueda Shohei、Pait Ivy Grace Umadhay、Nihira Takuya、Kitani Shigeru
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 74 Issue: 5 Pages: 359-362
- DOI
  10.1038/s41429-020-00404-z
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07045
[Journal Article] Kuanoniamine C stimulates bortezomib-induced cell death via suppression of glucose-regulated protein 78 in osteosarcoma2020
- Author(s)
  Kayo Machihara , Takushi Namba
- Journal Title
  
  Biochem Biophys Res Commun
  
  Volume: 527 Issue: 1 Pages: 289-296
- DOI
  10.1016/j.bbrc.2020.04.109
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07045
[Journal Article] BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites2019
- Author(s)
  Namba Takushi
- Journal Title
  
  Science Advances
  
  Volume: 5 Issue: 6
- DOI
  10.1126/sciadv.aaw1386
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07045
[Journal Article] Identification of biosynthetic genes for the β-carboline alkaloid kitasetaline and production of the fluorinated derivatives by heterologous expression2019
- Author(s)
  Ueda, S., Ikeda, H., Namba, T., Ikejiri, Y., Nishimoto, Y., Arai, M., Nihira, T., Kitani, S.,
- Journal Title
  
  J. Ind. Microbiol. Biotechnol.
  
  Volume: - Issue: 5 Pages: 739-750
- DOI
  10.1007/s10295-019-02151-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-16H06447, KAKENHI-PROJECT-18K05390, KAKENHI-PROJECT-19K07045, KAKENHI-PUBLICLY-18H04618, KAKENHI-PROJECT-18H02096
[Journal Article] BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX172019
- Author(s)
  Machihara Kayo、Namba Takushi
- Journal Title
  
  Cells
  
  Volume: 8 Issue: 11 Pages: 1350-1350
- DOI
  10.3390/cells8111350
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07045
[Journal Article] Andrographolide induces degradation of mutant p53 via activation of Hsp70.2018
- Author(s)
  Sato H, Hiraki M, Namba T, Egawa N, Baba K, Tanaka T, Noshiro H.
- Journal Title
  
  Int J Oncol.
  
  Volume: 53 Pages: 761-770
- DOI
  10.3892/ijo.2018.4416
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-16K18874
[Journal Article] Losing p53 loosens up ER-stress2015
- Author(s)
  Byun, S., Namba, T., and Lee, S. W.
- Journal Title
  
  Aging
  
  Volume: 7 Pages: 895-896
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893181
[Journal Article] Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.2015
- Author(s)
  Hiraki, M., Hwang, S. Y., Cao, S., Ramadhar, T. R., Byun, S., Yoon, K. W., Lee, K. H., Chu, K., Gurkar, A. U., Kolev, V., Zhang, J., Namba, T., Murphy, M. E., Newman, D. J., Mandinova, A., Clardy, J., and Lee, S. W.
- Journal Title
  
  Chemstry & Biology
  
  Volume: 22 Issue: 9 Pages: 1206-1216
- DOI
  10.1016/j.chembiol.2015.07.016
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893181
[Journal Article] Regulation of endoplasmic reticulum function2015
- Author(s)
  Namba T
- Journal Title
  
  Aging
  
  Volume: 7 Pages: 901-902
- Open Access
- Data Source
  KAKENHI-PROJECT-26893181
[Journal Article] Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.2015
- Author(s)
  Namba, T., Chu, K., Kodama, K., Byun, S., Yoon, KW., Hiraki, M., Mandinova, A., and Lee, S. W.
- Journal Title
  
  Oncotarget
  
  Volume: 24 Issue: 24 Pages: 19990-20001
- DOI
  10.18632/oncotarget.4598
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-26893181
[Patent] アンチエイジング剤およびその製造方法2021
- Inventor(s)
  難波卓司、町原加代
- Industrial Property Rights Holder
  難波卓司、町原加代
- Industrial Property Rights Type
  特許
- Filing Date
  2021
- Data Source
  KAKENHI-PROJECT-19K07045
[Presentation] Rejuvenating effect of lotus germ extract on senescent fibroblast via DAPK1-Beclin-1 pathway induced autophagy2021
- Author(s)
  Namba, T., Machihara S., Iwahashi K
- Organizer
  6th International Cell Senescence Association
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07045
[Presentation] BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX17.2019
- Author(s)
  Kayo Machihara, Takushi Namba
- Organizer
  ASCB/EMBO 2019 meeting. P539/B552. Washington, DC. December 7-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07045
[Presentation] Bap31 Regulates Mitochondrial Function In ER-Mitochondria Contact Site.2019
- Author(s)
  Takushi Namba
- Organizer
  ASCB/EMBO 2019 meeting. P539/B552. Washington, DC. December 7-11
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07045
[Presentation] 糖尿病の発症に関与する小胞体とミトコンドリアの新たな恒常性維持機構 ~小胞体とミトコンドリアのクロストーク~2018
- Author(s)
  難波卓司
- Organizer
  糖尿病学術講演会
- Invited
- Data Source
  KAKENHI-PROJECT-16K18874
[Presentation] 小胞体-ミトコンドリアタンパク質複合体によるミトコンドリアの恒常性維持機構の解明2018
- Author(s)
  難波卓司
- Organizer
  小胞体ストレス研究会
- Data Source
  KAKENHI-PROJECT-16K18874
[Presentation] 小胞体膜タンパク質B-cell receptor-associated protein 31はautophagyとapoptosisの誘導を制御する2017
- Author(s)
  難波卓司
- Organizer
  2017年度生命科学系学会合同年次大会
- Data Source
  KAKENHI-PROJECT-16K18874
[Presentation] The suppression of endoplasmic reticulum function is a new anti-cancer target2017
- Author(s)
  Takushi Namba
- Organizer
  The 11th International Kuroshio Science Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-16K18874
[Presentation] p53の機能喪失はIRE1/XBP1経路の活性化を誘導し、癌細胞における小胞体の機能を亢進させる
- Author(s)
  難波卓司
- Organizer
  第9回　臨床ストレス応答学会
- Place of Presentation
  岡山大学
- Year and Date
  2014-11-01 – 2014-11-02
- Data Source
  KAKENHI-PROJECT-26893181
[Presentation] p53の機能喪失はIRE1/XBP1経路の活性化を誘導し、癌細胞における小胞体の機能を亢進させる
- Author(s)
  難波卓司
- Organizer
  第87回日本生化学会大会
- Place of Presentation
  京都
- Year and Date
  2014-10-15 – 2014-10-18
- Data Source
  KAKENHI-PROJECT-26893181

1. 東洋一郎 (80380062)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 平岡雅規 (30380306)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 櫻井哲也 (90415167)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. Machihara Kayo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 池田治生

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Namba Takushi 難波 卓司

Takushi Namba 難波 卓司

Research Projects

Research Products

Co-Researchers

ゲノム解析から解き明かす共生細菌によるミナミアオノリの成長促進作用の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Mitochondrial function regulated by the endoplasmic reticulum membrane protein BAP31 is associated with neurological disorders.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

To identify new tummor suppressive factor, which regulates autophagy and apoptosis.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Analysis of p53 new function for protein synthesis and identification of new anti-cancer targetPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] ミトコンドリアダイナミクス2021

Author(s)

Total Pages

Publisher

ISBN

Data Source

[Journal Article] Lavencidin, a polyene macrolide antibiotic from Streptomyces lavendulae FRI-52021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kuanoniamine C stimulates bortezomib-induced cell death via suppression of glucose-regulated protein 78 in osteosarcoma2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BAP31 regulates mitochondrial function via interaction with Tom40 within ER-mitochondria contact sites2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Identification of biosynthetic genes for the β-carboline alkaloid kitasetaline and production of the fluorinated derivatives by heterologous expression2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] BAP31 Inhibits Cell Adaptation to ER Stress Conditions, Negatively Regulating Autophagy Induction by Interaction with STX172019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Andrographolide induces degradation of mutant p53 via activation of Hsp70.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Losing p53 loosens up ER-stress2015

Author(s)

Journal Title

Data Source

[Journal Article] Small-Molecule Reactivation of Mutant p53 to Wild-Type-like p53 through the p53-Hsp40 Regulatory Axis.2015

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Regulation of endoplasmic reticulum function2015

Author(s)

Journal Title

Data Source

[Journal Article] Loss of p53 enhances the function of the endoplasmic reticulum through activation of the IRE1α/XBP1 pathway.2015

Author(s)

Namba Takushi 難波卓司

Takushi Namba 難波卓司

[Presentation] 糖尿病の発症に関与する小胞体とミトコンドリアの新たな恒常性維持機構 ~小胞体とミトコンドリアのクロストーク~2018