Okura Sadayuki 大倉定之

… Alternative Names

Ohkura Sadayuki 大倉定之

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Researcher Number	10731036
Other IDs
Affiliation (Current)	2025: 日本医科大学, 医学部, 助教
Affiliation (based on the past Project Information) *help	2020 – 2024: 日本医科大学, 医学部, 助教 2015 – 2018: 日本医科大学, 医学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 49030:Experimental pathology-related / Laboratory animal science Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related
Keywords	Principal Investigator HIV-1 / host factor / capsid / proteomics / host factor / bat / retrovirus / 造血系幹細胞 / 間葉系・間質系幹細胞 / 自然免疫 … More / 造血幹細胞 / 感染 / 自然免疫応答 / ウイルス / ウイルス感染 / ヒト化マウス / AIDS … More Except Principal Investigator 内在性ウイルス / マルチオミックス解析 / エクソソーム / 胎盤形成不全 / 妊娠高血圧症候群 / 妊娠 / DROSHA / ウイルス感染 / 胎盤 / 産科学 Less

Multiomics analysis of exosome-delivering, virus-derived factors in the feto-matarnal interface for hypertensive dosorder of pregnancy
- Principal Investigator
  
  磯村真理子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nippon Medical School
コウモリ細胞ライブラリ由来の宿主因子によるHIV-1キャプシド標的抑制分子の作出Principal Investigator
- Principal Investigator
  
  大倉定之
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49030:Experimental pathology-related
- Research Institution
  Nippon Medical School
Elucidation of the novel function of trophoblast DROSHA as a novel therapeutic strategy for preventing congenital viral infection
- Principal Investigator
  
  Takizawa Toshihiro
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Nippon Medical School
Examination of innate immune responses in the local mucosal surfaces in the acute phase of HIV-1 infection using a humanized mice modelPrincipal Investigator
- Principal Investigator
  
  Ohkura Sadayuki
- Project Period (FY)
  2015 – 2018
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Research Field
  
  Laboratory animal science
- Research Institution
  Nippon Medical School

All 2024 2023 2019 2018 2017 2016

All Journal Article Presentation

[Journal Article] Cytoplasmic and nuclear DROSHA in human villous trophoblasts2024
- Author(s)
  Noguchi Syunya、Ohkura Sadayuki、Negishi Yasuyuki、Tozawa Shohei、Takizawa Takami、Morita Rimpei、Takahashi Hironori、Ohkuchi Akihide、Takizawa Toshihiro
- Journal Title
  
  Journal of Reproductive Immunology
  
  Volume: 162 Pages: 104189-104189
- DOI
  10.1016/j.jri.2023.104189
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K16843, KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-20K09611
[Journal Article] Characterization of Megabat-Favored, CA-Dependent Susceptibility to Retrovirus Infection2023
- Author(s)
  Ohkura Sadayuki、Horie Masayuki、Shimizu Masumi、Nakagawa So、Osanai Haruka、Miyagawa Yoshitaka、Morita Rimpei
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 3
- DOI
  10.1128/jvi.01803-22
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07140, KAKENHI-PROJECT-23K06503
[Journal Article] Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells2018
- Author(s)
  Otsuka Y, Watanabe E, Shinya E, Okura S, Saeki H, Geijtenbeek TBH, Takahashi H
- Journal Title
  
  Journal of Immunology
  
  Volume: 201 Issue: 10 Pages: 3006-3016
- DOI
  10.4049/jimmunol.1701402
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K06811, KAKENHI-PROJECT-16K09262
[Journal Article] Induction of langerin+ Langerhans cell-like cells expressing reduced TLR3 from CD34+ cord blood cells stimulated with GM-CSF, TGF-β1, and TNF-α 2016
- Author(s)
 Hideko Azuma, Eri Watanabe, Yohei Ohtsuka, Yasuyuki Negishi, Sadayuki Ohkura, Eiji Shinya, and Hidemi Takahashi
- Journal Title
 
 Biomed. Res.
 
 Volume: 37 Issue: 5 Pages: 271-281
- DOI
 10.2220/biomedres.37.271
- NAID
 130005432962
- ISSN
 0388-6107, 1880-313X
- Language
 English
- Peer Reviewed / Acknowledgement Compliant / Open Access / Int'l Joint Research
- Data Source
 KAKENHI-PROJECT-15K06811, KAKENHI-PROJECT-16K09262
[Presentation] HIV-1 capsid coreに結合するコウモリ宿主因子の網羅的プロテオーム解析2023
- Author(s)
  大倉　定之
- Organizer
  日本エイズ学会
- Data Source
  KAKENHI-PROJECT-23K06503
[Presentation] 栄養膜細胞株BeWoを用いたウイルス感染における栄養膜細胞DROSHAの動態解析2023
- Author(s)
  野口隼矢、大倉定之、根岸靖幸、森田林平、大口昭英、高橋宏典、瀧澤俊広
- Organizer
  第31回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09611
[Presentation] 胎盤絨毛栄養膜細胞のmiRNA生合成酵素DROSHAに結合するRNA：fCLIP解析2023
- Author(s)
  瀧澤俊広、野口隼矢、大倉定之、根岸靖幸、森田林平、大口昭英、高橋宏典
- Organizer
  第31回日本胎盤学会学術集会
- Data Source
  KAKENHI-PROJECT-20K09611
[Presentation] Comprehensive proteomic analysis of the HIV-1-inhibiting mechanism in non-permissive megabat cells2023
- Author(s)
  大倉　定之
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-23K06503
[Presentation] HIV-1 Nef, in cooperation with Hematopoietic cell kinase (Hck), augmented the interaction between SERINC5 and SERINC3, towards the increase of intrinsic infectivity of HIV-1 particles2019
- Author(s)
  Eiji SHINYA, Atsuko OWAKI, Masumi SHIMIZU, Jiro MATSUMURA, Sadayuki OKURA, Hidemi TAKAHASHI
- Organizer
  日本免疫学会
- Data Source
  KAKENHI-PROJECT-15K06811
[Presentation] Hematopoietic cell kinase (Hck) augmented the interaction between HIV-1 Nef and SERINC5, which might promote HIV-1 infection by excluding SERINC5 from virion incorporation in immature dendritic cells2017
- Author(s)
  Eiji Shinya, Atsuko Owaki, Jiro Matsumura, Sadayuki Okura, Yohei Otsuka, Shun Takaku, Hidemi Takahashi
- Organizer
  日本免疫学会総会
- Data Source
  KAKENHI-PROJECT-15K06811

1. 根岸靖幸 (50644580)

# of Collaborated Projects: 3 results

# of Collaborated Products: 2 results
2. 石野孔祐 (60584878)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Takizawa Toshihiro (90271220)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 大口昭英 (10306136)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
5. 高橋宏典 (80544303)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 磯村真理子 (90893222)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 堀江真行 (20725981)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. Maruyama Motoyo

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. Shimizu Masumi

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
10. 森田林平

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
11. 野口隼矢

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Okura Sadayuki 大倉 定之

Ohkura Sadayuki 大倉 定之

Research Projects

Research Products

Co-Researchers

Multiomics analysis of exosome-delivering, virus-derived factors in the feto-matarnal interface for hypertensive dosorder of pregnancy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

コウモリ細胞ライブラリ由来の宿主因子によるHIV-1キャプシド標的抑制分子の作出Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the novel function of trophoblast DROSHA as a novel therapeutic strategy for preventing congenital viral infection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Examination of innate immune responses in the local mucosal surfaces in the acute phase of HIV-1 infection using a humanized mice modelPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Cytoplasmic and nuclear DROSHA in human villous trophoblasts2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Megabat-Favored, CA-Dependent Susceptibility to Retrovirus Infection2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Differentiation of Langerhans Cells from Monocytes and Their Specific Function in Inducing IL-22-Specific Th Cells2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] <b>Induction of langerin</b><sup><b>+</b></sup><b> Langerhans cell-like cells expressing reduced TLR3 from CD34</b><sup><b>+</b></sup><b> cord blood cells stimulated with GM-CSF, TGF-β1, and </b><b>TNF-α </b>2016

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] HIV-1 capsid coreに結合するコウモリ宿主因子の網羅的プロテオーム解析2023

Author(s)

Organizer

Data Source

[Presentation] 栄養膜細胞株BeWoを用いたウイルス感染における栄養膜細胞DROSHAの動態解析2023

Author(s)

Organizer

Data Source

[Presentation] 胎盤絨毛栄養膜細胞のmiRNA生合成酵素DROSHAに結合するRNA：fCLIP解析2023

Author(s)

Organizer

Data Source

[Presentation] Comprehensive proteomic analysis of the HIV-1-inhibiting mechanism in non-permissive megabat cells2023

Author(s)

Organizer

Data Source

[Presentation] HIV-1 Nef, in cooperation with Hematopoietic cell kinase (Hck), augmented the interaction between SERINC5 and SERINC3, towards the increase of intrinsic infectivity of HIV-1 particles2019

Author(s)

Organizer

Data Source

[Presentation] Hematopoietic cell kinase (Hck) augmented the interaction between HIV-1 Nef and SERINC5, which might promote HIV-1 infection by excluding SERINC5 from virion incorporation in immature dendritic cells2017

Author(s)

Organizer

Data Source

Okura Sadayuki 大倉定之

Ohkura Sadayuki 大倉定之