Matsuda Yukiko 松田由喜子

… Alternative Names

MATSUDA Yukiko 松田由喜子

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Researcher Number	10735301
Other IDs
Affiliation (Current)	2025: 公益財団法人放射線影響研究所, 分子生物科学部, 研究員
Affiliation (based on the past Project Information) *help	2020 – 2025: 公益財団法人放射線影響研究所, 分子生物科学部, 研究員 2019 – 2021: 広島大学, 原爆放射線医科学研究所, 研究員 2015: 広島大学, 原爆放射線医科学研究所, 研究員 2014: 広島大学, 原爆放射線医科学研究所, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 63020:Radiation influence-related / Basic Section 52020:Neurology-related / Neurology Except Principal Investigator Basic Section 63020:Radiation influence-related
Keywords	Principal Investigator 脊髄小脳変性症 / 変異シグネチャー / 体細胞変異 / 放射線 / CACNA1G / プルキンエ細胞 / 脂肪酸代謝 / ペルオキシソーム Except Principal Investigator 体細胞変異 / バイオドシメトリ … More / 造血幹細胞 / 変異シグネチャー / DNA損傷 / クロマチン構造 / DNA損傷修復 / 放射線被曝 / 放射線被ばく / クローン造血 / 老化 / クローン化 / 悪性腫瘍 / 晩発障害 / 全ゲノムシーケンス解析 / 骨髄性白血病 / 変異マウス / 白血病 / 胸腺リンパ腫 / Keap1 / NRF2 / 酸化ストレス応答 / 活性酸素 / X線 / 全ゲノムシーケンス Less

Genome-wide mapping of radiation-induced DNA double-strand breaks to elucidate mutation processes
- Principal Investigator
  
  田邉修
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Analysis of changes in radiation-induced mutational signatures induced by DNA repair inhibitors and their impact on carcinogenic risk.Principal Investigator
- Principal Investigator
  
  松田由喜子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Time-resolved biodosimetry based on clonal hematopoiesis and somatic mutations in atomic-bomb survivors
- Principal Investigator
  
  吉田健吾
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells
- Principal Investigator
  
  田邉修
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
A new oligonucleotide treatment with CRISPR/Cas13 using model mice of spinocerebellar ataxiaPrincipal Investigator
- Principal Investigator
  
  MATSUDA Yukiko
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Hiroshima University
Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and Mutagenesis
- Principal Investigator
  
  TANABE Osamu
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 63020:Radiation influence-related
- Research Institution
  Radiation Effects Research Foundation
The mechanism of neuronal cell death induced by a new mutation of peroxisomal enzyme via the mitochondorial disfunctionPrincipal Investigator
- Principal Investigator
  
  Matsuda Yukiko
- Project Period (FY)
  2014 – 2015
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Neurology
- Research Institution
  Hiroshima University

All 2023 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells2023
- Author(s)
  Matsuda Yukiko、Uchimura Arikuni、Satoh Yasunari、Kato Naohiro、Toshishige Masaaki、Kajimura Junko、Hamasaki Kanya、Yoshida Kengo、Hayashi Tomonori、Noda Asao、Tanabe Osamu
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 120 Issue: 15
- DOI
  10.1073/pnas.2216550120
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K12388, KAKENHI-PROJECT-23K28234
[Journal Article] Kv11 (ether-a-go-go-related gene) voltage-dependent K + channels promote resonance and oscillation of subthreshold membrane potentials2021
- Author(s)
  Matsuoka Toshinori, Yamasaki Miwako, Abe Manabu, Matsuda Yukiko, Morino Hiroyuki, Kawakami Hideshi, Sakimura Kenji, Watanabe Masahiko, Hashimoto Kouichi
- Journal Title
  
  The Journal of Physiology
  
  Volume: 599(2) Issue: 2 Pages: 547-569
- DOI
  10.1113/jp280342
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02540, KAKENHI-PROJECT-16H06276, KAKENHI-PROJECT-16H06280, KAKENHI-PROJECT-17K01972, KAKENHI-PROJECT-17H03551, KAKENHI-PROJECT-20H03410, KAKENHI-PROJECT-18KK0458
[Journal Article] Middle-age-onset cerebellar ataxia caused by a homozygous TWNK variant: a case report2020
- Author(s)
  Kume Kodai、Morino Hiroyuki、Miyamoto Ryosuke、Matsuda Yukiko、Ohsawa Ryosuke、Kanaya Yuhei、Tada Yui、Kurashige Takashi、Kawakami Hideshi
- Journal Title
  
  BMC Medical Genetics
  
  Volume: 21(1) Issue: 1
- DOI
  10.1186/s12881-020-01002-4
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994
[Journal Article] Genetic screening for potassium channel mutations in Japanese autosomal dominant spinocerebellar ataxia2020
- Author(s)
  Tada Yui、Kume Kodai、Matsuda Yukiko、Kurashige Takashi、Kanaya Yuhei、Ohsawa Ryosuke、Morino Hiroyuki、Tabu Hayato、Kaneko Satoshi、Suenaga Toshihiko、Kakizuka Akira、Kawakami Hideshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65(4) Issue: 4 Pages: 363-369
- DOI
  10.1038/s10038-019-0717-y
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-19H03435
[Journal Article] Retinitis pigmentosa prior to familial ALS caused by a homozygous cilia and flagella-associated protein 410 mutation2020
- Author(s)
  Kurashige Takashi、Morino Hiroyuki、Matsuda Yukiko、Mukai Tomoya、Murao Tomomi、Toko Megumi、Kume Kodai、Ohsawa Ryosuke、Torii Tsuyoshi、Tokinobu Hiroshi、Maruyama Hirofumi、Kawakami Hideshi
- Journal Title
  
  Journal of Neurology, Neurosurgery & Psychiatry
  
  Volume: 91(2) Issue: 2 Pages: 220-222
- DOI
  10.1136/jnnp-2019-321279
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07994
[Journal Article] Optineurin regulates osteoblastogenesis through STAT12020
- Author(s)
  Mizuno Noriyoshi、Iwata Tomoyuki、Ohsawa Ryosuke、Ouhara Kazuhisa、Matsuda Shinji、Kajiya Mikihito、Matsuda Yukiko、Kume Kodai、Tada Yui、Morino Hiroyuki、Yoshimoto Tetsuya、Ueki Yasuyoshi、Mihara Keichiro、Sotomaru Yusuke
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 525(4) Issue: 4 Pages: 889-894
- DOI
  10.1016/j.bbrc.2020.03.028
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599, KAKENHI-PROJECT-19K18999
[Journal Article] Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutationresponsible for spinocerebellar ataxia2020
- Author(s)
  N. Hara, H. Morino, Y. Matsuda, K. Satoh, K. Hashimoto, H. Maruyama, H. Kawakami
- Journal Title
  
  Molecular Brain
  
  Volume: 13 Issue: 1 Pages: 163-163
- DOI
  10.1186/s13041-020-00700-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09125, KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-17H03551
[Journal Article] Aggressive periodontitis and NOD2 variants2020
- Author(s)
  Mizuno Noriyoshi, Kume Kodai, Nagatani Yukiko, Matsuda Shinji, Iwata Tomoyuki, Ouhara Kazuhisa, Kajiya Mikihito, Takeda Katsuhiro, Matsuda Yukiko, Tada Yui, Ohsawa Ryosuke, Morino Hiroyuki, Mihara Keichiro, Fujita Tsuyoshi, Kawaguchi Hiroyuki, Shiba Hideki, Kawakami Hideshi, Kurihara Hidemi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65(10) Issue: 10 Pages: 841-846
- DOI
  10.1038/s10038-020-0777-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994, KAKENHI-PROJECT-18H02978, KAKENHI-PROJECT-18K09599
[Journal Article] The first Japanese case of primary familial brain calcification caused by an MYORG variant2020
- Author(s)
  Kume Kodai, Takata Tadayuki, Morino Hiroyuki, Matsuda Yukiko, Ohsawa Ryosuke, Tada Yui, Kurashige Takashi, Kawakami Hideshi
- Journal Title
  
  Journal of Human Genetics
  
  Volume: 65(10) Issue: 10 Pages: 917-920
- DOI
  10.1038/s10038-020-0779-x
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07994
[Journal Article] Biallelic mutation of HSD17B4 induces middle age-onset spinocerebellar ataxia2020
- Author(s)
  Matsuda Yukiko、Morino Hiroyuki、Miyamoto Ryosuke、Kurashige Takashi、Kume Kodai、Mizuno Noriyoshi、Kanaya Yuhei、Tada Yui、Ohsawa Ryosuke、Yokota Kazunori、Shimozawa Nobuyuki、Maruyama Hirofumi、Kawakami Hideshi
- Journal Title
  
  Neurology Genetics
  
  Volume: 6(1) Issue: 1
- DOI
  10.1212/nxg.0000000000000396
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K07994
[Journal Article] C-terminal mutations in SYNE1 are associated with motor neuron disease in patients with SCAR82019
- Author(s)
  Kume Kodai、Morino Hiroyuki、Komure Osamu、Matsuda Yukiko、Ohsawa Ryosuke、Kurashige Takashi、Kanaya Yuhei、Tada Yui、Kawakami Hideshi
- Journal Title
  
  Journal of the Neurological Sciences
  
  Volume: 402 Pages: 118-120
- DOI
  10.1016/j.jns.2019.05.001
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K07994
[Presentation] Longitudinal trajectories of clonal hematopoiesis before and after 3-Gy whole-body irradiation in mice2023
- Author(s)
  Yoshida K, Uchimura A, Satou Y, Matsuda Y, Tanabe O, Noda A, Misumi M, Kusunoki Y
- Organizer
  17th International Congress of Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] X線照射によりマウス造血幹細胞に誘発される体細胞変異とクローン性増殖2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本放射線影響学会第66会大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide frequencies and signatures of somatic mutations introduced by whole-body X-irradiation in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  17th International Congress for Radiation Research
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  73rd Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Genome-wide analysis of radiation-induced somatic mutations in mouse long-term hematopoietic stem cells2023
- Author(s)
  Matsuda Y, Uchimura A, Satoh Y, Kato N, Toshishige M, Kume K, Kajimura J, Hamasaki K, Yoshida K, Hayashi T, Noda A, Tanabe O
- Organizer
  75th Annual Meeting of the American Society of Human Genetics
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K28234
[Presentation] 全身X線照射後のマウス造血幹細胞の体細胞変異とクローン動態の全ゲノムシーケンスによる解析2023
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、濱崎幹也、吉田健吾、林奉権、野田朝男、田邉修
- Organizer
  日本環境変異原ゲノム学会第52回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] X 線照射マウスの造血幹細胞における体細胞変異の頻度と特徴2022
- Author(s)
  田邉修、松田由喜子
- Organizer
  日本環境変異原ゲノム学会第51回大会
- Invited
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] X線照射によりマウス造血幹細胞に誘導される体細胞変異の頻度と特徴2022
- Author(s)
  松田由喜子、内村有邦、佐藤康成、加藤直広、利重匡亮、梶村順子、久保美子、山岡美佳、濱崎幹也、吉田健吾、野田朝男、田邉修
- Organizer
  日本放射線影響学会第 65 回大会
- Data Source
  KAKENHI-PROJECT-22K12388
[Presentation] Transcriptomic analysis using model mice of spinocerebellar ataxia 422021
- Author(s)
  Matsuda Y, Morino H, Sotomaru Y, Kurashige T, Maruyama H, Kawakami H.
- Organizer
  第62回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07994
[Presentation] Biochemical analysis of middle-age-onset SCAR caused by a biallelic mutation of HSD17B42020
- Author(s)
  Matsuda Y, Morino H, Kurashige T, Miyamoto R, Maruyama H, Kawakami H
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07994
[Presentation] Degeneration of cerebellar Purkinje cells in the knock-in mice harboring SCA42 mutation2019
- Author(s)
  Matsuda Y, Morino H, Kurashige T, Nakayama H, Matsuoka T, Sotomaru Y, Hashimoto K, Kawakami H
- Organizer
  第42回日本神経科学大会
- Data Source
  KAKENHI-PROJECT-19K07994
[Presentation] Homozygous mutation in dehydrogenase domain of DBP cause slowly progressive spinocerebellar ataxia2019
- Author(s)
  Matsuda Y, Morino H, Miyamoto R, Kawakami H
- Organizer
  第60回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-19K07994

1. TANABE Osamu (70221398)

# of Collaborated Projects: 5 results

# of Collaborated Products: 10 results
2. 内村有邦 (20513063)

# of Collaborated Projects: 3 results

# of Collaborated Products: 9 results
3. 吉田健吾 (70443596)

# of Collaborated Projects: 2 results

# of Collaborated Products: 9 results
4. 森野豊之 (10397953)

# of Collaborated Projects: 1 results

# of Collaborated Products: 13 results
5. 吉田稚明 (20832926)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 楠洋一郎 (60333548)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 濱崎幹也 (80443597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
8. 和氣加容子 (40649597)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 佐藤健一

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
10. 佐藤裕哉

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Matsuda Yukiko 松田 由喜子

MATSUDA Yukiko 松田 由喜子

Research Projects

Research Products

Co-Researchers

Genome-wide mapping of radiation-induced DNA double-strand breaks to elucidate mutation processes

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of changes in radiation-induced mutational signatures induced by DNA repair inhibitors and their impact on carcinogenic risk.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Time-resolved biodosimetry based on clonal hematopoiesis and somatic mutations in atomic-bomb survivors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Whole-genome sequence analysis of radiation-induced mutations in human hematopoietic stem cells

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A new oligonucleotide treatment with CRISPR/Cas13 using model mice of spinocerebellar ataxiaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Study on Protective Effects of NRF2, an Anti-oxidative Stress Transcription Factor, against Radiation-induced Oncogenesis and Mutagenesis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The mechanism of neuronal cell death induced by a new mutation of peroxisomal enzyme via the mitochondorial disfunctionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Spectra and characteristics of somatic mutations induced by ionizing radiation in hematopoietic stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Kv11 (ether-a-go-go-related gene) voltage-dependent K + channels promote resonance and oscillation of subthreshold membrane potentials2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Middle-age-onset cerebellar ataxia caused by a homozygous TWNK variant: a case report2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic screening for potassium channel mutations in Japanese autosomal dominant spinocerebellar ataxia2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Retinitis pigmentosa prior to familial ALS caused by a homozygous cilia and flagella-associated protein 410 mutation2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Optineurin regulates osteoblastogenesis through STAT12020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Zonisamide can ameliorate the voltage-dependence alteration of the T-type calcium channel CaV3.1 caused by a mutationresponsible for spinocerebellar ataxia2020

Author(s)

Journal Title

Matsuda Yukiko 松田由喜子

MATSUDA Yukiko 松田由喜子