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Fujiwara Ikuko  藤原 郁子

ORCIDConnect your ORCID iD *help
Researcher Number 10742075
Other IDs
Affiliation (Current) 2022: 長岡技術科学大学, 工学研究科, 准教授
Affiliation (based on the past Project Information) *help 2020: 大阪市立大学, 大学院理学研究科, 助教
2015 – 2019: 名古屋工業大学, 工学(系)研究科(研究院), 助教
Review Section/Research Field
Principal Investigator
Nanobioscience / Biophysics / Basic Section 43040:Biophysics-related
Except Principal Investigator
Biophysics
Keywords
Principal Investigator
アクチン / 細胞運動 / 細胞骨格 / アクチン制御メカニズム / キャッピングプロテイン / 重合・脱重合ダイナミクス / 一分子キネティクス / 生物物理一般 / 生命現象の物理 / 顕微鏡技術・イメージング … More / 生物物理・化学物理・ソフトマターの物理 / MreB / 重合 / ATP加水分解メカニズム / スピロプラズマ / MreB繊維の可視化 / A22 … More
Except Principal Investigator
アクチン / フラグミン / 構造空間 / 1分子 / ゲルゾリン / 動力学計算 / TIRF / 生物物理 / 一分子測定 / X線構造解析 Less
  • Research Projects

    (3 results)
  • Research Products

    (40 results)
  • Co-Researchers

    (10 People)
  •  TIRF visualization of the polymerization dynamics of bacterial actin cytoskeleton, MreB and A22 driven disruption mechanismPrincipal Investigator

    • Principal Investigator
      藤原 郁子
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 43040:Biophysics-related
    • Research Institution
      Osaka City University
  •  The mechanism for severging of F-actin by gelsolin-like protein

    • Principal Investigator
      Oda Toshiro
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Research Field
      Biophysics
    • Research Institution
      Tokai Gakuin University
  •  Roles of CP for actin polymerization to regulate cell protrusionsPrincipal Investigator

    • Principal Investigator
      Fujiwara Ikuko
    • Project Period (FY)
      2015 – 2017
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Nanobioscience
      Biophysics
    • Research Institution
      Nagoya Institute of Technology

All 2021 2020 2019 2018 2017 2016 2015

All Journal Article Presentation

  • [Journal Article] Crystal structure of human V-1 in the apo form2021

    • Author(s)
      Shuichi Takeda, Ryotaro Koike, Takayuki Nagae, Ikuko Fujiwara, Akihiro Narita, Yuichiro Maeda, Motonori Ota
    • Journal Title

      Acta Crystallographica Section F Structural Biology Communications

      Volume: 77 Pages: 13-21

    • DOI

      10.1107/s2053230x20016829

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-19K12217, KAKENHI-PROJECT-20K06522, KAKENHI-PROJECT-20K06591, KAKENHI-PUBLICLY-19H05390
  • [Journal Article] Novel inter-domain Ca2+-binding site in the gelsolin superfamily protein fragmin2020

    • Author(s)
      Shuichi Takeda , Ikuko Fujiwara, Yasunobu Sugimoto, Toshiro Oda, Akihiro Narita, Yuichiro Maéda
    • Journal Title

      Journal of Muscle Research and Cell Motility

      Volume: 41 Pages: 153-162

    • DOI

      10.1007/s10974-019-09571-5

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Journal Article] D-Loop Mutation G42A/G46A Decreases Actin Dynamics2020

    • Author(s)
      Matsuzaki Mizuki、Fujiwara Ikuko、Kashima Sae、Matsumoto Tomoharu、Oda Toshiro、Hayashi Masahito、Maeda Kayo、Takiguchi Kingo、Ma?da Yuichiro、Narita Akihiro
    • Journal Title

      Biomolecules

      Volume: 10 Pages: 736-736

    • DOI

      10.3390/biom10050736

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06591, KAKENHI-PROJECT-18H02410
  • [Journal Article] Phylogenetic origin and sequence features of MreB from the wall-less swimming bacteria Spiroplasma2020

    • Author(s)
      Takahashi Daichi、Fujiwara Ikuko、Miyata Makoto
    • Journal Title

      Biochemical and Biophysical Research Communications

      Volume: 533 Pages: 638-644

    • DOI

      10.1016/j.bbrc.2020.09.060

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Journal Article] Myosin 18Aα targets the guanine nucleotide exchange factor β‐Pix to the dendritic spines of cerebellar Purkinje neurons and promotes spine maturation2020

    • Author(s)
      Alexander Christopher J.、Barzik Melanie、Fujiwara Ikuko、Remmert Kirsten、Wang Ya‐Xian、Petralia Ronald S.、Friedman Thomas B.、Hammer John A.
    • Journal Title

      The FASEB Journal

      Volume: 35

    • DOI

      10.1096/fj.202001449r

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Journal Article] Latrunculin A Depolymerizes Actin Filaments by Binding Terminal Subunits and by Sequestering Actin Monomers2019

    • Author(s)
      藤原郁子
    • Journal Title

      Biophysics

      Volume: 59 Issue: 4 Pages: 192-196

    • DOI

      10.2142/biophys.59.192

    • NAID

      130007683539

    • ISSN
      0582-4052, 1347-4219
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Journal Article] Polymerization and depolymerization of actin with nucleotide states at filament ends2018

    • Author(s)
      Fujiwara Ikuko、Takeda Shuichi、Oda Toshiro、Honda Hajime、Narita Akihiro、Ma?da Yuichiro
    • Journal Title

      Biophys Rev

      Volume: 10 Pages: 1513-1519

    • DOI

      10.1007/s12551-018-0483-7

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07373, KAKENHI-PROJECT-16K14708
  • [Journal Article] Latrunculin A Accelerates Actin Filament Depolymerization in Addition to Sequestering Actin Monomers2018

    • Author(s)
      Fujiwara Ikuko、Zweifel Mark E.、Courtemanche Naomi、Pollard Thomas D.
    • Journal Title

      Current Biology

      Volume: 28

    • DOI

      10.1016/j.cub.2018.07.082

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Journal Article] タンパク質の創発する集合知2017

    • Author(s)
      藤原郁子
    • Journal Title

      学会紀要 (日本人工知能学会 第3回 市民共創研究会)1

      Volume: - Pages: 34-38

    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Journal Article] Keeping the focus on biophysics and actin filaments in Nagoya: A report of the 2016 “now in actin” symposium2017

    • Author(s)
      Fujiwara I, Narita A
    • Journal Title

      Cytoskeleton

      Volume: 12 Pages: 450-464

    • DOI

      10.1002/cm.21384

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15K21106, KAKENHI-PROJECT-17K07373
  • [Presentation] Development of Spiroplasma swimming motor from bacterial actin MreB2021

    • Author(s)
      Daichi Takahashi、Ikuko Fujiwara, Makoto Miyata
    • Organizer
      BLAST XVI online
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Presentation] Polymerization of bacterial actin MreB involved in swimming mitility of Spiroplasma eriocheiris2021

    • Author(s)
      Daichi Takahashi、Ikuko Fujiwara, Makoto Miyata
    • Organizer
      BLAST XVI online
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Presentation] 細菌アクチンMreBからスピロプラズマ遊泳モーターへの進化2020

    • Author(s)
      Daichi Takahashi, Ikuko Fujiwara, Makoto Miyata
    • Organizer
      第58回日本生物物理学会年会 オンライン開催
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Presentation] Structures and dynamics of bacterial actin homolog, mreB proteins involved in swimming motility ofSpiroplasma eriocheiris2020

    • Author(s)
      Daichi Takahashi, Ikuko Fujiwara, Katsumi Imada, Makoto Miyata
    • Organizer
      第20回日本タンパク質k学会年会 オンライン開催
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Presentation] 螺旋推進する細菌スピロプラズマ内のアクチン様タンパク質MreBの重合観察2020

    • Author(s)
      Ikuko Fujiwara, Daichi Takahashi, Yuhei O. Tahara, Yuya Sasajima, Hana Kiyama, Makoto Miyata
    • Organizer
      第43回日本分子生物学会年会 MBSJ 2020 Online
    • Data Source
      KAKENHI-PROJECT-20K06591
  • [Presentation] ラトランキュリンAはF型からG型へのコンフォメーション変化を誘起しアクチン脱重合を促進する2019

    • Author(s)
      武田 修一, 藤原 郁子, 小田 俊郎, 成田 哲博, 前田 雄一郎
    • Organizer
      日本結晶学会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Polymerization of bacterial actin MreB involved in swimming motility of Spiroplasma eriocheiris2019

    • Author(s)
      Takahashi, D., Fujiwara, I. and Miyata, M.
    • Organizer
      The 11th Toyota Riken International Workshop"Actin Filament: beyond the atomic resolution structures"
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] ダイナミンGTPアーゼはアクチン線維の束化と分散を機械的に制御する2019

    • Author(s)
      武居孝二 、 テ モン ラ、 阿部 匡、竹田哲也、藤原郁子、成田哲博
    • Organizer
      第57回日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Cell motility based on the polymerization dynamics”2019

    • Author(s)
      Fujiwara, I., Takahashi, D., Sasajima, Y., Remmert, K., Hammer, J. and Miyata, M.
    • Organizer
      International Workshop on Quantum Sensing & Biophotonics
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] TIRF 観察によるアクチン重合・脱重合における蛍光標識の影響2019

    • Author(s)
      藤原郁子、武田修一、成田哲博、小田俊郎、前田雄一郎、Naomi Courtemanche、Thomas Pollard
    • Organizer
      第57回日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] “Bacterial actin homolog, MreBs and fibril are essential for the swimming motility of Spiroplasma eriocheiris”,2019

    • Author(s)
      Fujiwara, I., Takahashi, D., Sasajima, Y., Kiyama, H., Arakawa, A., Kato, K., Miyata, T., Kakizawa, S., Namba, K. and Miyata, M.
    • Organizer
      The 11th Toyota Riken International Workshop"Actin Filament: beyond the atomic resolution structures"
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Spiroplasmaの遊泳運動に必須な細菌アクチンMreB2019

    • Author(s)
      高橋大地、藤原郁子、宮田真人
    • Organizer
      2020年生体運動研究合同班会議
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] BL2S1を利用したX線結晶構造解析から明らかとなったアクチン重合・ATP加水分解機構2019

    • Author(s)
      武田修一、成田哲博、小田俊郎、小池亮太郎、森次圭、太田元規、兼松佑典、藤原郁子、田中康太郎、永江峰幸、渡邉信久、前田雄一郎
    • Organizer
      第8回名古屋大学シンクロトロン光研究センターシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Analysis of the picosecond dynamics of muscle contractile proteins and their hydration water by quasielastic neutron scattering2018

    • Author(s)
      Tatsuhito Matsuo, Toshiaki Arata, Toshiro Oda, Kenji Nakajima, Seiko Kawamura, Tatsuya Kikuchi, Taiki Tominaga, Kaoru Shibata, Fumiaki Kono, Satoru Fujiwara
    • Organizer
      日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Atomic resolution structures of F‐form actin: mutual switching between G/F transition and ATPase2018

    • Author(s)
      Shuichi Takeda, Akihiro Narita, Toshiro Oda, Nobuhisa Watanabe, Takayuki Nagae, Motonori Ota, Ryotaro Koike, Kei Moritsugu, Yusuke Kanematsu, Ikuko Fujiwara, Kotaro Tanaka, Yuichiro Maéda
    • Organizer
      The 47th European muscle conference
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] 高分解能X線結晶構造から明らかとなったアクチン重合・ATP加水分解機構2018

    • Author(s)
      武田 修一、成田 哲博、小田 俊郎、田中 康太郎、小池 亮太郎、太田 元規、藤原 郁子、永江峰幸、渡邉 信久、前田 雄一郎
    • Organizer
      名古屋大学シンクロトロン光研究センターシンポジウム
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Regulation of actin bundles by using LOV-fused fascin2018

    • Author(s)
      Ikuko Fujiwara, Miki Iwatani, Yumeka Yamauchi, Tatsuya Iwata, Shuichi Takeda, Toshiro Oda, Tomoharu Matsumoto, Akihiro Narita, Satoshi Tsunoda, Hideki Kandori
    • Organizer
      日本生物物理学会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] The structure of F-form actin at atomic resolutions: mutual switching between polymorphic transition and ATPase2018

    • Author(s)
      Shuichi Takeda, Akihiro Narita, Toshiro Oda, Nobuhisa Watanabe, Y, Takayuki Nagae, Motonori Ota, Ryotaro Koike, Kei Moritsugu, Yusuke Kanematsu, Ikuko Fujiwara, Kotaro Tanaka, Yuichiro Maéda
    • Organizer
      Myofilament conference 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] F-form crystal structures: Mechanisms of actin assembly and F-actin ATPase2018

    • Author(s)
      Shuichi Takeda, Akihiro Narita, Toshiro Oda, Kotaro Tanaka, Ryotaro Koike, Motonori Ota, Ikuko Fujiwara, Nobuhisa Watanabe, Yuichiro Maéda
    • Organizer
      The 62th Annual Meeting of Biophysical Society
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] ATPase mechanism and dynamic assembly of actin revealed by the F-form crystal structures2017

    • Author(s)
      武田 修一、成田 哲博、小田俊郎、田中 康太郎、小池 亮太郎、太田 元規、藤原 郁子、渡邉 信久、前田 雄一郎
    • Organizer
      第55回日本生物物理学会年会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] タンパク質の創発する集合知2017

    • Author(s)
      藤原郁子
    • Organizer
      第3回 市民共創研究会 名古屋工業大学
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Severing regulation of gelsolin superfamily on single and bundled actin filaments2017

    • Author(s)
      Fujiwara,I., Fan,R., Takeda,S., Maéda,Y., Narita, A
    • Organizer
      International Symposium, Harmonized supramolecular motility machinery and its diversity, Nagoya, Japan 09/2017
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Regulation of actin bundles by using LOV-fused fascin2017

    • Author(s)
      Fujiwara, I., Iwatani, M., Tsunoda,S., Kandori, H.
    • Organizer
      Optogentics Research Society Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] タンパク質の創発する集合知2017

    • Author(s)
      藤原郁子
    • Organizer
      日本人工知能学会 第3回 市民共創研究会
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] 高分解能X線結晶構造から明らかとなったアクチン重合・ATP加水分解機構2017

    • Author(s)
      武田 修一、成田 哲博、小田 俊郎、田中 康太郎、小池 亮太郎、太田 元規、藤原 郁子、渡邉 信久、前田 雄一郎
    • Organizer
      平成29年度日本結晶学会年会
    • Data Source
      KAKENHI-PROJECT-17K07373
  • [Presentation] Severing regulation of gelsolin superfamily on single and bundled actin filaments2017

    • Author(s)
      Fujiwara,I., Fan,R., Takeda,S., Maéda,Y., Narita, A.
    • Organizer
      International Symposium, Harmonized supramolecular motility machinery and its diversity, Nagoya, Japan
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] アクチン骨格阻害剤Latrunculin-Aはアクチンを脱重合させ重合を阻害する2016

    • Author(s)
      藤原郁子
    • Organizer
      生物物理 (第54回年会)
    • Place of Presentation
      つくば国際会議場
    • Year and Date
      2016-11-25
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] アクチン重合阻害試薬「ラトランキュリン-A」はアクチンモノマーだけでなくフィラメントにも結合してアクチン脱重合を促進する2016

    • Author(s)
      藤原郁子
    • Organizer
      日本生体エネルギー研究会 (第42回年会)
    • Place of Presentation
      名古屋工業大学
    • Year and Date
      2016-12-19
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] Polymerization and regulatory functions determined by single actin filaments observation2016

    • Author(s)
      Ikuko Fujiwara
    • Organizer
      Now in actin study-Motor protein research reaching a new stage-
    • Place of Presentation
      名古屋大学
    • Year and Date
      2016-12-12
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-15K21106
  • [Presentation] Biochemical and functional characterization of the effects of a single point mutation on mouse CP to CARMIL binding2015

    • Author(s)
      藤原 郁子, Alexander Christopher, Remmert Kirsten, Piszcek Grzegorz, Hammer John
    • Organizer
      第53回日本生物物理学会年会
    • Place of Presentation
      金沢大学 角間キャンパス 自然科学本館
    • Year and Date
      2015-09-13
    • Data Source
      KAKENHI-PROJECT-15K21106
  • 1.  TAKEDA Shuichi (50509081)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 15 results
  • 2.  ODA Toshiro (20321739)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 14 results
  • 3.  KANDORI Hideki (70202033)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 4.  TSUNODA Satoshi (10158983)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  MAEDA Yuichiro (10321811)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 6.  HAMMER John
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 7.  POLLARD Thomas
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 8.  COURTEMANCHE Naomi
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 9.  Ryotaro Koike
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 10.  成田 哲博
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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