Koga Junichiro 古賀純一郎

… Alternative Names

Researcher Number	10746142
Other IDs
Affiliation (Current)	2021: 九州大学, 大学病院, 学術研究員
Affiliation (based on the past Project Information) *help	2019: 九州大学, 大学病院, 学術研究員 2016 – 2018: 九州大学, 循環器病未来医療研究センター, 学術研究員 2015: 九州大学, 学内共同利用施設等, 研究員
Review Section/Research Field	Principal Investigator Cardiovascular medicine / Basic Section 53020:Cardiology-related
Keywords	Principal Investigator 分子血管学 / 動脈硬化 / マクロファージ / ミトコンドリアダイナミクス / ナノメディスン / 分子血管額学 / 炎症 / 活性酸素 / 心筋梗塞後リモデリング / 線維化 / 循環器内科学 / 心筋虚血再灌流障害 / 急性心筋梗塞

Mitochondrial dynamics in myocardial ischemia-reperfusion injury and post-infarct remodelingPrincipal InvestigatorOngoing
- Principal Investigator
  
  古賀純一郎
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53020:Cardiology-related
- Research Institution
  Kyushu University
Monocyte/macrophage Drp1 in the pathobiology of atherosclerotic vascular diseasesPrincipal Investigator
- Principal Investigator
  
  KOGA Junichiro
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyushu University
PPARgamma-targeting Nanomedicine for the Treatment of Atherosclerotic Plaque RupturePrincipal Investigator
- Principal Investigator
  
  Junchiro Koga
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Cardiovascular medicine
- Research Institution
  Kyushu University

All 2019 2018 2017 2016 2015

All Journal Article Presentation Book

[Book] Nanoparticle-mediated Endothelial Cell-selective Drug Delivery System.2017
- Author(s)
  Nakano K, Koga J, Egashira K
- Publisher
  Therapeutic Angiogenesis.
- Data Source
  KAKENHI-PROJECT-15K19384
[Book] Mouse Models of Atherosclerosis.2016
- Author(s)
  Iwata H, Koga J, Decano J, Choi J, Mlynarchik AK, Mattson PC, Aikawa E, Aikawa M.
- Total Pages
  35
- Publisher
  Mouse Models of Vascular Diseases.
- Data Source
  KAKENHI-PROJECT-15K19384
[Journal Article] Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice.2019
- Author(s)
  Fujiwara Masaki、Matoba Tetsuya、Koga Jun-Ichiro、Okahara Arihide、Funamoto Daiki、Nakano Kaku、Tsutsui Hiroyuki、Egashira Kensuke
- Journal Title
  
  Cardiovascular Research
  
  Volume: in press
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16011
[Journal Article] Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models2018
- Author(s)
  Tokutome Masaki、Matoba Tetsuya、Nakano Yasuhiro、Okahara Arihide、Fujiwara Masaki、Koga Jun-Ichiro、Nakano Kaku、Tsutsui Hiroyuki、Egashira Kensuke
- Journal Title
  
  Cardiovascular Research
  
  Volume: 115 Pages: 419-431
- DOI
  10.1093/cvr/cvy200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K09590, KAKENHI-PROJECT-17K16011
[Journal Article] Safety, Tolerability, and Pharmacokinetics of NK-104-NP2018
- Author(s)
  Nakano Kaku、Matoba Tetsuya、Koga Jun-ichiro、Kashihara Yushi、Fukae Masato、Ieiri Ichiro、Shiramoto Masanari、Irie Shin、Kishimoto Junji、Todaka Koji、Egashira Kensuke
- Journal Title
  
  International Heart Journal
  
  Volume: 59(5) Issue: 5 Pages: 1015-1025
- DOI
  10.1536/ihj.17-555
- NAID
  130007490519
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16011
[Journal Article] Lipid-Lowering Therapy With Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion: A Role of Serum Oxysterols.2018
- Author(s)
  K. Honda, T. Matoba, Y. Antoku, J.I. Koga, I. Ichi, K. Nakano, H. Tsutsui, K. Egashira
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 38 Pages: 757-771
- DOI
  10.1161/atvbaha.117.310244
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K00848, KAKENHI-PROJECT-17K16011
[Journal Article] Nanoparticle-Mediated Targeting of Pitavastatin to Small Pulmonary Arteries and Leukocytes by Intravenous Administration Attenuates the Progression of Monocrotaline-Induced Established Pulmonary Arterial Hypertension in Rats2018
- Author(s)
  Ichimura Kenzo、Matoba Tetsuya、Koga Jun-ichiro、Nakano Kaku、Funamoto Daiki、Tsutsui Hiroyuki、Egashira Kensuke
- Journal Title
  
  International Heart Journal
  
  Volume: 59(6) Issue: 6 Pages: 1432-1444
- DOI
  10.1536/ihj.17-683
- NAID
  130007522561
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16011
[Journal Article] Anti-inflammatory Nanomedicine for Cardiovascular Disease.2017
- Author(s)
  Katsuki Shunsuke、Matoba Tetsuya、Koga Jun-ichiro、Nakano Kaku、Egashira Kensuke
- Journal Title
  
  Front Cardiovasc Med.
  
  Volume: 4 Pages: 1383-1395
- DOI
  10.3389/fcvm.2017.00087
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09590, KAKENHI-PROJECT-17K16011
[Journal Article] Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Left Ventricular Remodeling After Acute Myocardial Infarction by Inhibiting Monocyte-Mediated Inflammation2017
- Author(s)
  Mao Y, Koga JI, Tokutome M, Matoba T, Ikeda G, Nakano K, Egashira K
- Journal Title
  
  International Heart Journal
  
  Volume: 58(4) Issue: 4 Pages: 615-623
- DOI
  10.1536/ihj.16-457
- NAID
  130005901270
- ISSN
  1349-2365, 1349-3299
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K16011
[Journal Article] Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.2016
- Author(s)
  Nakano T, Fukuda D, Koga J, Aikawa M
- Journal Title
  
  Arteriosclerosis, Thrombosis, and Vascular Biology
  
  Volume: 36(10) Pages: 2038-2047
- DOI
  10.1161/atvbaha.116.306926
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19384, KAKENHI-PROJECT-16K09517
[Journal Article] BubR1 Insufficiency Results in Decreased Macrophage Proliferation and Attenuated Atherogenesis in Apolipoprotein E-Deficient Mice.2016
- Author(s)
  Tanaka S, Matsumoto T, Matsubara Y, Harada Y, Kyuragi R, Koga JI, Egashira K, Nakashima Y, Yonemitsu Y, Maehara Y
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5(9)
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15K19384
[Journal Article] Anti-inflammatory Nanoparticle for Prevention of Atherosclerotic Vascular Diseases.2016
- Author(s)
  Koga J, Matoba T, Egashira K.
- Journal Title
  
  Journal of Atherosclerosis and Thrombosis.
  
  Volume: 印刷中
- NAID
  130005160389
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19384
[Journal Article] Nanoparticle-mediated delivery of pitavastatin to monocytes/macrophages inhibits left ventricular remodeling after acute myocardial infarction by inhibiting monocyte-mediated inflammation.2016
- Author(s)
  Mao Y, Koga J, Tokutome M, Matoba T, Ikeda G, Nakano K, Egashira K
- Journal Title
  
  Int Heart J.
  
  Volume: 印刷中
- NAID
  130005901270
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-15K19384
[Journal Article] Pioglitazone-Incorporated Nanoparticles Prevent Plaque Destabilization and Rupture by Regulating Monocyte/Macrophage Differentiation in ApoE-/- Mice.2016
- Author(s)
  Nakashiro S, Matoba T, Umezu R, Koga J, Tokutome M, Katsuki S, Nakano K, Sunagawa K, Egashira K.
- Journal Title
  
  Arterioscler Thromb Vasc Biol.
  
  Volume: 36(3) Pages: 491-500
- DOI
  10.1161/atvbaha.115.307057
- Peer Reviewed / Acknowledgement Compliant
- Data Source
  KAKENHI-PROJECT-15K19384, KAKENHI-PROJECT-25461135
[Journal Article] Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation.2016
- Author(s)
  Nakano Y, Matoba T, Tokutome M, Funamoto D, Katsuki S, Ikeda G, Nagaoka K, Ishikita A, Nakano K, Koga J, Sunagawa K, Egashira K
- Journal Title
  
  Sci Rep.
  
  Volume: 6 Pages: 29601-29601
- DOI
  10.1038/srep29601
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461131, KAKENHI-PROJECT-15K19384
[Journal Article] A Translational Study of a New Therapeutic Approach for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin into Reperfused Myocardium Reduces Ischemia-Reperfusion Injury in a Preclinical Porcine Model.2016
- Author(s)
  Ichimura K, Matoba T, Nakano K, Tokutome M, Honda K, Koga J, Egashira K
- Journal Title
  
  PLoS One.
  
  Volume: 11(9)
- DOI
  10.1371/journal.pone.0162425
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461131, KAKENHI-PROJECT-15K19384
[Journal Article] Nanoparticle-Mediated Delivery of Mitochondrial Division Inhibitor 1 to the Myocardium Protects the Heart From Ischemia-Reperfusion Injury Through Inhibition of Mitochondria Outer Membrane Permeabilization: A New Therapeutic Modality for Acute Myocardial Infarction.2016
- Author(s)
  Ishikita A, Matoba T, Ikeda G, Koga J, Mao Y, Nakano K, Takeuchi O, Sadoshima J, Egashira K
- Journal Title
  
  J Am Heart Assoc.
  
  Volume: 5(7)
- DOI
  10.1161/jaha.116.003872
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-26461131, KAKENHI-PROJECT-15K19384
[Journal Article] 冠動脈疾患に対するナノ粒子・ドラッグデリバリーシステムの開発2015
- Author(s)
  的場哲哉、古賀純一郎、中野覚、江頭健輔
- Journal Title
  
  Drug Delivery System.
  
  Volume: 30(4) Pages: 299-308
- NAID
  130005116532
- Data Source
  KAKENHI-PROJECT-15K19384
[Presentation] Macrophage dynamin-related protein 1, a mitochondrial fission protein, promotes inflammation and vascular remodeling after mechanical injury in mice.2019
- Author(s)
  Jun-ichiro Koga, Ryuta Umezu, Tetsuya Matoba, Hiroyuki Tsutsui, Kensuke Egashira.
- Organizer
  The 3rd JCS Council Forum on Basic CardioVascular Research
- Data Source
  KAKENHI-PROJECT-19K08518
[Presentation] ミトコンドリアダイナミクスによるマクロファージ機能制御と血管病.2019
- Author(s)
  古賀　純一郎，的場　哲哉，蓮澤　奈央，野村　政壽，江頭　健輔，筒井　裕之.
- Organizer
  Cardiovascular and Metabolic Week 2019
- Invited
- Data Source
  KAKENHI-PROJECT-19K08518
[Presentation] Macrophage dynamin-related protein 1, a mitochondrial fission protein, accelerates inflammation and neointimal thickening after vascular injury2018
- Author(s)
  Jun-ichiro Koga, Ryuta Umezu, Tetsuya Matoba, Hiroyuki Tsutsui, Kensuke Egashira
- Organizer
  第82回日本循環器学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16011
[Presentation] Macrophage Dynamin-related Protein1 Promotes Neointima Formation after Mechanical Injury in Mouse Femoral Arteries.2017
- Author(s)
  Koga J, Umezu R, Egashira K
- Organizer
  第5回 IRG (Inflammation and ReGeneration) Meeting
- Place of Presentation
  品川プリンスホテル（東京都・港区）
- Year and Date
  2017-01-06
- Data Source
  KAKENHI-PROJECT-15K19384
[Presentation] マクロファージに発現するミトコンドリア形態制御分子Drp1はマウス大腿動脈において血管傷害後の内膜肥厚を促進する2017
- Author(s)
  古賀純一郎、梅津隆太、的場哲哉、王麗香、野村政壽、江頭健輔
- Organizer
  第49回日本動脈硬化学会総会・学術集会
- Data Source
  KAKENHI-PROJECT-17K16011
[Presentation] Macrophage Dynamin-related Protein1 Promotes Neointima Formation after Mechanical Injury in Mouse Femoral Arteries2016
- Author(s)
  Umezu R, Koga J, Wang L, Nomura M, Egashira K
- Organizer
  19th International Vascular Biology Meeting 2016
- Place of Presentation
  ボストン（アメリカ）
- Year and Date
  2016-10-30
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19384
[Presentation] Macrophage Dynamin-related Protein1 Promotes Neointima Formation after Mechanical Injury in Mouse Femoral Arteries2016
- Author(s)
  Koga J, Umezu R, Wang L, Nomura M, Egashira K
- Organizer
  第24回日本血管生物医学会学術集会
- Place of Presentation
  長崎ブリックホール（長崎県・長崎市）
- Year and Date
  2016-12-08
- Data Source
  KAKENHI-PROJECT-15K19384
[Presentation] Nanotechnology-based anti-atherosclerotic therapy targeting monocytes-mediated inflammation.2015
- Author(s)
  Koga J
- Organizer
  The 13th. Japan-Korea Joint Symposium on Vascular Biology.
- Place of Presentation
  釜山(韓国)
- Year and Date
  2015-10-16
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15K19384

1. MATOBA Tetsuya

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
2. ICHI Ikuyo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
3. 福田大受

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 江頭健輔

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
5. 中野覚

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results

Koga Junichiro 古賀 純一郎

Junchiro Koga 古賀 純一郎

Research Projects

Research Products

Co-Researchers

Mitochondrial dynamics in myocardial ischemia-reperfusion injury and post-infarct remodelingPrincipal InvestigatorOngoing

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Monocyte/macrophage Drp1 in the pathobiology of atherosclerotic vascular diseasesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

PPARgamma-targeting Nanomedicine for the Treatment of Atherosclerotic Plaque RupturePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] Nanoparticle-mediated Endothelial Cell-selective Drug Delivery System.2017

Author(s)

Publisher

Data Source

[Book] Mouse Models of Atherosclerosis.2016

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Nanoparticle incorporating Toll-like receptor 4 inhibitor attenuates myocardial ischaemia-reperfusion injury by inhibiting monocyte-mediated inflammation in mice.2019

Author(s)

Journal Title

Data Source

[Journal Article] Peroxisome proliferator-activated receptor-gamma targeting nanomedicine promotes cardiac healing after acute myocardial infarction by skewing monocyte/macrophage polarization in preclinical animal models2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Safety, Tolerability, and Pharmacokinetics of NK-104-NP2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Lipid-Lowering Therapy With Ezetimibe Decreases Spontaneous Atherothrombotic Occlusions in a Rabbit Model of Plaque Erosion: A Role of Serum Oxysterols.2018

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanoparticle-Mediated Targeting of Pitavastatin to Small Pulmonary Arteries and Leukocytes by Intravenous Administration Attenuates the Progression of Monocrotaline-Induced Established Pulmonary Arterial Hypertension in Rats2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Anti-inflammatory Nanomedicine for Cardiovascular Disease.2017

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nanoparticle-Mediated Delivery of Pitavastatin to Monocytes/Macrophages Inhibits Left Ventricular Remodeling After Acute Myocardial Infarction by Inhibiting Monocyte-Mediated Inflammation2017

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Journal Article] Delta-Like Ligand 4-Notch Signaling in Macrophage Activation.2016

Author(s)

Journal Title

DOI

Data Source

Koga Junichiro 古賀純一郎

Junchiro Koga 古賀純一郎