Maeda Tomoya 前田智也

Researcher Number	10754252
Other IDs
Affiliation (Current)	2025: 北海道大学, 農学研究院, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 北海道大学, 農学研究院, 助教 2018 – 2019: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 基礎科学特別研究員
Review Section/Research Field	Principal Investigator Basic Section 43060:System genome science-related / Complex systems Except Principal Investigator Basic Section 43060:System genome science-related / Basic Section 38020:Applied microbiology-related
Keywords	Principal Investigator 微生物相互作用 / 共生 / マイクロバイオーム / 進化実験 / 進化可能性 / 実験室進化 / 薬剤耐性進化 / 多剤耐性結核 / 結核菌 / 代謝リレー … More / 腸内細菌 / コリネ型細菌 / 大腸菌 / 酸化還元バランス / NADHデヒドロゲナーゼ / 呼吸鎖 / 中枢代謝 / 酸化的リン酸化 / 適応的実験室進化 / 環境微生物 / バクテリア / 細菌 / 異種ゲノム融合 / プロトプラスト / 水平伝播 / 細胞融合 … More Except Principal Investigator ラボオートメーション / 微生物生態系 / 生態系 / 原核生物 / 進化実験 / γーアミノ酪酸 / 1,3-ブタンジオール / γ-アミノ酪酸 / グルタミン酸 / 呼吸鎖 / 大腸菌 Less

非病原性ウシ型結核菌BCG株を用いた進化実験による多剤耐性進化可能性の検証Principal Investigator
- Principal Investigator
  
  前田智也
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Hokkaido University
Analysis of evolutionary dynamics of ecosystem using automated culture system
- Principal Investigator
  
  古澤力
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Institute of Physical and Chemical Research
腸内マイクロバイオームの大規模継代培養による栄養共生関係の解明Principal Investigator
- Principal Investigator
  
  前田智也
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Adaptive laboratory evolution of Escherichia coli and Corynebacterium glutamicum mutant strains lacking genes encoding respiratory chain enzymes and/or NADH dehydrogenases.Principal Investigator
- Principal Investigator
  
  Tomoya Maeda
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Hokkaido University
Identification of interaction network of environmental microorganisms by high-throughput laboratory evolution.Principal Investigator
- Principal Investigator
  
  前田智也
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
- Review Section
  
  Complex systems
- Research Institution
  Hokkaido University
Metabolic analysis of an Escherichia coli mutant defective in respiratory chain enzymes and its application to the production of 1,3-butanediol and gamma-aminobutyric acid.
- Principal Investigator
  
  Atsushi Yokota
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 38020:Applied microbiology-related
- Research Institution
  Hokkaido University
Construction and analysis of bacterial strains carrying heterologous bacterial genome by heterologous protoplast fusion.Principal Investigator
- Principal Investigator
  
  Maeda Tomoya
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 43060:System genome science-related
- Research Institution
  Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Laboratory Evolution of Antimicrobial Resistance in Bacteria to Develop Rational Treatment Strategies2024
- Author(s)
  Maeda Tomoya、Furusawa Chikara
- Journal Title
  
  Antibiotics
  
  Volume: 13 Issue: 1 Pages: 94-94
- DOI
  10.3390/antibiotics13010094
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06142, KAKENHI-PUBLICLY-22H04876, KAKENHI-PROJECT-19H05626
[Journal Article] Adaptive Laboratory Evolution of Microorganisms: Methodology and Application for Bioproduction2022
- Author(s)
  Hirasawa Takashi、Maeda Tomoya
- Journal Title
  
  Microorganisms
  
  Volume: 11 Issue: 1 Pages: 92-92
- DOI
  10.3390/microorganisms11010092
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06142, KAKENHI-PUBLICLY-22H04876
[Journal Article] Mutational property of newly identified mutagen l-glutamic acid γ-hydrazide in Escherichia coli2021
- Author(s)
  Maeda Tomoya、Shibai Atsushi、Yokoi Naomi、Tarusawa Yumeko、Kawada Masako、Kotani Hazuki、Furusawa Chikara
- Journal Title
  
  Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
  
  Volume: 823 Pages: 111759-111759
- DOI
  10.1016/j.mrfmmm.2021.111759
- Peer Reviewed
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PUBLICLY-20H05591, KAKENHI-PROJECT-19H05626
[Journal Article] Morphological change of coiled bacterium Spirosoma linguale with acquisition of β-lactam resistance2021
- Author(s)
  Maeda Tomoya、Kotani Hazuki、Furusawa Chikara
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 13278-13278
- DOI
  10.1038/s41598-021-92787-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PUBLICLY-20H05591
[Journal Article] Laboratory evolution of Mycobacterium on agar plates for analysis of resistance acquisition and drug sensitivity profiles2021
- Author(s)
  Maeda Tomoya、Kawada Masako、Sakata Natsue、Kotani Hazuki、Furusawa Chikara
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 15136-15136
- DOI
  10.1038/s41598-021-94645-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PUBLICLY-20H05591, KAKENHI-PROJECT-19H05626
[Journal Article] High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli2020
- Author(s)
  Maeda Tomoya、Iwasawa Junichiro、Kotani Hazuki、Sakata Natsue、Kawada Masako、Horinouchi Takaaki、Sakai Aki、Tanabe Kumi、Furusawa Chikara
- Journal Title
  
  Nature Communications
  
  Volume: 11 Issue: 1 Pages: 5970-5970
- DOI
  10.1038/s41467-020-19713-w
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PROJECT-19H05626, KAKENHI-PROJECT-18J21942, KAKENHI-PROJECT-16H06279, KAKENHI-PUBLICLY-20H05591
[Journal Article] High-throughput identification of the sensitivities of an Escherichia coli ΔrecA mutant strain to various chemical compounds2019
- Author(s)
  Maeda Tomoya、Horinouchi Takaaki、Sakata Natsue、Sakai Aki、Furusawa Chikara
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: - Issue: 7 Pages: 1-8
- DOI
  10.1038/s41429-019-0160-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PUBLICLY-18H04807, KAKENHI-PROJECT-17H03622, KAKENHI-PROJECT-17K15052, KAKENHI-PROJECT-15H05746, KAKENHI-PROJECT-18K14688
[Journal Article] Complete Genome Sequences of Three Star-Shaped Bacteria, Stella humosa, Stella vacuolata, and Stella Species ATCC 351552019
- Author(s)
  Shibai Atsushi、Maeda Tomoya、Kawada Masako、Kotani Hazuki、Sakata Natsue、Furusawa Chikara
- Journal Title
  
  Microbiology Resource Announcements
  
  Volume: 8 Issue: 32
- DOI
  10.1128/mra.00719-19
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-17H06389, KAKENHI-PROJECT-18K14688
[Journal Article] Toward prediction and control of antibiotic-resistance evolution2018
- Author(s)
  Furusawa Chikara、Horinouchi Takaaki、Maeda Tomoya
- Journal Title
  
  Current Opinion in Biotechnology
  
  Volume: 54 Pages: 45-49
- DOI
  10.1016/j.copbio.2018.01.026
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15052, KAKENHI-PROJECT-17H03622, KAKENHI-PROJECT-18K14688, KAKENHI-PLANNED-17H06389, KAKENHI-PROJECT-15H05746
[Journal Article] Understanding and engineering alcohol-tolerant bacteria using OMICS technology2018
- Author(s)
  Horinouchi Takaaki、Maeda Tomoya、Furusawa Chikara
- Journal Title
  
  World Journal of Microbiology and Biotechnology
  
  Volume: 34 Issue: 11 Pages: 1-9
- DOI
  10.1007/s11274-018-2542-4
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14688, KAKENHI-PUBLICLY-18H04807, KAKENHI-PROJECT-17K15052
[Presentation] 大腸菌呼吸鎖変異株ΔNDH-IΔCytbo3を用いたグルコースからのGABA の高生産2024
- Author(s)
  若原　洋輝、溝越　拓哉、吹谷　智、横田　篤、前田　智也
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] ST合剤を用いた大腸菌の二剤併用薬剤耐性進化実験2024
- Author(s)
  後藤　琉、小谷　葉月、吹谷　智、古澤　力、前田　智也
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 他の腸内細菌存在下における大腸菌の薬剤耐性進化実験2024
- Author(s)
  永野　有佳理、小谷　葉月、吹谷　智、古澤　力、前田　智也
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] ヒト腸内細菌叢の大規模継代培養実験による微生物相互作用の解析2024
- Author(s)
  前田　智也、吹谷　智、古澤　力
- Organizer
  日本農芸化学会2024年度大会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 大規模継代培養実験による微生物生態系の再構成2023
- Author(s)
  前田智也
- Organizer
  第4回シンポジウム・ビフィズス菌研究会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 異種間相互作用による薬剤耐性進化ダイナミクスへの影響2023
- Author(s)
  前田智也，古澤力
- Organizer
  第一回北海道バイオ"Mix-up"
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 実験室進化による大腸菌のエネルギーおよび酸化還元バランスの不均衡化に対する適応機構の解明2023
- Author(s)
  山上　晃汰郎、小谷　葉月、吹谷　智、古澤　力、前田　智也
- Organizer
  第17回ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] 他の腸内細菌存在下における大腸菌の薬剤耐性進化実験2023
- Author(s)
  永野有佳理、小谷葉月、吹谷智、古澤力、前田智也
- Organizer
  第17回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 実験室進化による大腸菌のエネルギーおよび酸化還元バランスの不均衡化に対する適応機構の解明2023
- Author(s)
  山上晃汰郎、小谷葉月、吹谷智、古澤力、前田智也
- Organizer
  第17 回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] 実験室進化による大腸菌のエネルギー欠乏への潜在的な適応能力の解明2023
- Author(s)
  山上　晃汰郎、小谷　葉月、吹谷　智、古澤　力、前田　智也
- Organizer
  2023 年度日本農芸化学会北海道支部第２回学術講演会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] 9種細菌の薬剤耐性進化実験による薬剤耐性進化ダイナミクスの比較解析2023
- Author(s)
  前田智也、田邊久美、芝井厚、小谷　葉月、古澤　力
- Organizer
  第17回ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 9種細菌の薬剤耐性進化実験による薬剤耐性進化ダイナミクスの比較解析2023
- Author(s)
  前田　智也、田邊　久美、芝井　厚、小谷　葉月、古澤力
- Organizer
  第17回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] Comparative analysis of antibiotic resistance dynamics by high-throughput laboratory evolution of 9 bacterial species2023
- Author(s)
  Tomoya Maeda, Kumi Tanabe, Atsushi Shibai, Hazuki Kotani, Chikara Furusawa
- Organizer
  FEMS2023
- Int'l Joint Research
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 呼吸鎖変異大腸菌株を用いたグルコースからのGABAの高生産2022
- Author(s)
  若原　洋輝、溝越　拓哉、前田　智也、吹谷　智、横田　篤
- Organizer
  日本農芸化学会2022年度大会
- Data Source
  KAKENHI-PROJECT-19H02863
[Presentation] Laboratory evolution of bacterial multispecies community for antibiotic resistance2022
- Author(s)
  前田　智也、古澤　力
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PUBLICLY-22H04876
[Presentation] 大腸菌におけるエネルギーおよび酸化還元レベルと表現型の関係2022
- Author(s)
  前田　智也
- Organizer
  日本遺伝学会第94回大会
- Invited
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] 呼吸鎖変異大腸菌株を用いたグルコースからのGABAの高生産2022
- Author(s)
  若原洋輝、溝越拓哉、前田智也、吹谷智、横田篤
- Organizer
  日本農芸化学会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] マイクロバイオームの大規模継代培養実験による共生関係の解明2022
- Author(s)
  前田　智也、古澤　力
- Organizer
  第16回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PUBLICLY-20H05591
[Presentation] 大腸菌の呼吸鎖変異株におけるグルタミン酸異常蓄積機構の解析2021
- Author(s)
  今　壮太、前田　智也、吹谷　智、和田　大、横田　篤
- Organizer
  日本生物工学会北日本支部会２０２１年度第一回オンラインシンポジウム
- Data Source
  KAKENHI-PROJECT-19H02863
[Presentation] 大規模進化実験で解き明かす大腸菌の薬剤耐性進化における制約2021
- Author(s)
  前田智也，岩澤諄一郎，古澤力
- Organizer
  第93回日本細菌学会総会
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05591
[Presentation] 実験室進化による薬剤耐性進化ダイナミクスの解析2021
- Author(s)
  前田　智也、岩澤　諄一郎、古澤　力
- Organizer
  日本生物工学会北日本支部会 2021年度第一回オンライン若手シンポジウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05591
[Presentation] 大腸菌の呼吸鎖変異株におけるグルタミン酸脱水素酵素及び、グルタミン酸合成酵素の欠損がグルタミン酸異常蓄積に及ぼす影響2021
- Author(s)
  今壮太, 前田智也, 吹谷智, 和田大, 横田篤
- Organizer
  日本生物工学会
- Data Source
  KAKENHI-PROJECT-21K06142
[Presentation] 異種間相互作用による薬剤耐性進化ダイナミクスへの影響2021
- Author(s)
  前田　智也、古澤　力
- Organizer
  第15 回細菌学若手コロッセウム
- Invited
- Data Source
  KAKENHI-PUBLICLY-20H05591
[Presentation] 大腸菌の呼吸鎖変異株におけるグルタミン酸脱水素酵素及び、グルタミン酸合成酵素の欠損がグルタミン酸異常蓄積に及ぼす影響2021
- Author(s)
  今　壮太、前田　智也、吹谷　智、和田　大、横田　篤
- Organizer
  第73回日本生物工学会大会
- Data Source
  KAKENHI-PROJECT-19H02863
[Presentation] 非病原性結核菌の抗結核剤に対する進化実験2020
- Author(s)
  前田智也、古澤力
- Organizer
  第14回日本ゲノム微生物学会
- Data Source
  KAKENHI-PROJECT-18K14688
[Presentation] 全自動培養システムを用いた多種ストレス環境下における大腸菌の大規模実験室進化2019
- Author(s)
  前田智也、岩澤諄一郎、堀之内貴明、阪田奈津枝、川田正子、小谷葉月、酒井亜希、田邊久美、古澤力
- Organizer
  第13回日本ゲノム微生物学会年会
- Data Source
  KAKENHI-PROJECT-18K14688
[Presentation] 全自動培養システムを用いた多種ストレス環境下における大腸菌の大規模進化実験2019
- Author(s)
  前田智也、岩澤諄一郎、堀之内貴明、阪田奈津江、小谷葉月、川田正子、田邊久美、古澤力
- Organizer
  第13回日本ゲノム微生物学会
- Data Source
  KAKENHI-PROJECT-18K14688
[Presentation] Identification of mutations conferring resistance to anti-tuberculosis drugs by laboratory evolution of non-pathogenic Mycobacterium on agar plate.2019
- Author(s)
  Tomoya Maeda, Chikara Furusawa
- Organizer
  ICSB2019 The 20th International Conference on System Biology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14688
[Presentation] 全自動培養システムを用いた多種ストレス環境下における大腸菌の大規模実験室進化2018
- Author(s)
  前田智也、堀之内貴明、阪田奈津枝、川田正子、小谷葉月、酒井亜希、田邊久美、古澤力
- Organizer
  第17 回微生物研究会
- Data Source
  KAKENHI-PROJECT-18K14688
[Presentation] High-throughput experimental evolution of Escherichia coli under various stress environments using an automated culture system2018
- Author(s)
  Tomoya Maeda, Takaaki Horinouchi, Natsue Sakata, Hazuki Kotani, Aki Sakai, Kumi Tanabe, Chikara Furusawa
- Organizer
  第46回内藤コンファレンス
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14688

1. Atsushi Yokota (50220554)

# of Collaborated Projects: 2 results

# of Collaborated Products: 6 results
2. 片岡尚也 (50713509)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 和田大 (00301416)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 中島千絵 (60435964)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 鈴木定彦 (90206540)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 古澤力 (00372631)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
7. 堀之内貴明

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Maeda Tomoya 前田 智也

Research Projects

Research Products

Co-Researchers

非病原性ウシ型結核菌BCG株を用いた進化実験による多剤耐性進化可能性の検証Principal Investigator

Principal Investigator

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Analysis of evolutionary dynamics of ecosystem using automated culture system

Principal Investigator

Project Period (FY)

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Review Section

Research Institution

腸内マイクロバイオームの大規模継代培養による栄養共生関係の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Adaptive laboratory evolution of Escherichia coli and Corynebacterium glutamicum mutant strains lacking genes encoding respiratory chain enzymes and/or NADH dehydrogenases.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of interaction network of environmental microorganisms by high-throughput laboratory evolution.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Metabolic analysis of an Escherichia coli mutant defective in respiratory chain enzymes and its application to the production of 1,3-butanediol and gamma-aminobutyric acid.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction and analysis of bacterial strains carrying heterologous bacterial genome by heterologous protoplast fusion.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Laboratory Evolution of Antimicrobial Resistance in Bacteria to Develop Rational Treatment Strategies2024

Author(s)

Journal Title

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[Journal Article] Adaptive Laboratory Evolution of Microorganisms: Methodology and Application for Bioproduction2022

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[Journal Article] Mutational property of newly identified mutagen l-glutamic acid γ-hydrazide in Escherichia coli2021

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[Journal Article] Morphological change of coiled bacterium Spirosoma linguale with acquisition of β-lactam resistance2021

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[Journal Article] Laboratory evolution of Mycobacterium on agar plates for analysis of resistance acquisition and drug sensitivity profiles2021

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[Journal Article] High-throughput laboratory evolution reveals evolutionary constraints in Escherichia coli2020

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[Journal Article] High-throughput identification of the sensitivities of an Escherichia coli ΔrecA mutant strain to various chemical compounds2019

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Maeda Tomoya 前田智也

[Presentation] 大規模継代培養実験による微生物生態系の再構成2023

[Presentation] 実験室進化による大腸菌のエネルギーおよび酸化還元バランスの不均衡化に対する適応機構の解明2023

[Presentation] 実験室進化による大腸菌のエネルギーおよび酸化還元バランスの不均衡化に対する適応機構の解明2023

[Presentation] 9種細菌の薬剤耐性進化実験による薬剤耐性進化ダイナミクスの比較解析2023

[Presentation] 9種細菌の薬剤耐性進化実験による薬剤耐性進化ダイナミクスの比較解析2023