Kinoshita Makoto 木下淳

Researcher Number	10755648
Other IDs	https://orcid.org/0000-0001-5447-7232
Affiliation (Current)	2025: 東京大学, 医学部附属病院, 講師
Affiliation (based on the past Project Information) *help	2025: 東京大学, 医学部附属病院, 講師 2020 – 2023: 東京大学, 医学部附属病院, 助教 2018 – 2019: 東京大学, 医学部附属病院, 登録診療員 2017: 東京大学, 医学部附属病院, 助教 2016: 東京大学, 医学部附属病院, 登録診療員 2015: 東京大学, 医学部附属病院, 助教
Review Section/Research Field	Principal Investigator Basic Section 56050:Otorhinolaryngology-related / Otorhinolaryngology Except Principal Investigator Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields / Basic Section 56050:Otorhinolaryngology-related
Keywords	Principal Investigator めまい / 前庭 / 内リンパ水腫 / メニエール病 / 生活指導 / プロテオーム解析 / 7, 8-DHF / TrkB受容体 / 内耳 / 神経栄養因子 … More / 神経科学 / TrkB / BDNF / 難聴 / 内耳障害 / ＳＯＤ２ / ＭｎＳＯＤ / ミトコンドリア / 酸化ストレス / 騒音性難聴 / SOD2 / MnSOD … More Except Principal Investigator 内耳 / 前庭 / 蝸牛 / ミトコンドリア / 薬剤徐放 / ドラッグ・デリバリー / 薬剤局所投与 / めまい / スタチン / 良性発作性頭位めまい症 / 骨粗鬆症 / 耳石 / 平衡覚 / 組織 / 活性酸素 / 三次元構造 / 病理 / 組織透明化 / 解剖 / 有毛細胞 / 三半規管 / ミトファジー / autophagy / 酸化ストレス / ミトコンドリア病 / 加齢性難聴 / オートファジー Less

Basic research on the effects of various lifestyle guidance recommendations for Meniere's disease on the occurrence of attacksPrincipal Investigator
- Principal Investigator
  
  木下淳
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Tokyo
Drug delivery treatment for benign paroxysmal positional vertigo
- Principal Investigator
  
  吉川弥生
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Tokyo
メニエール病モデル動物における内耳水代謝関連タンパクの発現変化に関する研究Principal Investigator
- Principal Investigator
  
  木下淳
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 56050:Otorhinolaryngology-related
- Research Institution
  The University of Tokyo
A study of the role of mitophagy in hearing disorder
- Principal Investigator
  
  Yamasoba Tatsuya
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Comprehensive analysis of inner ear pathology by a new imaging technique using a transparent method
- Principal Investigator
  
  Yamasoba Tatsuya
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (A)
- Review Section
  
  Medium-sized Section 56:Surgery related to the biological and sensory functions and related fields
- Research Institution
  The University of Tokyo
Construction of a new inner ear treatment strategy by orally administrable TrkB agonistPrincipal Investigator
- Principal Investigator
  
  Kinoshita Makoto
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo
Elucidation of the processing mechanism of reactive oxygen species in the inner ear in MnSOD genetically modified animalsPrincipal Investigator
- Principal Investigator
  
  Kinoshita Makoto
- Project Period (FY)
  2015 – 2016
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Otorhinolaryngology
- Research Institution
  The University of Tokyo

All 2023 2022 2020 2019 2017 2016 2015

All Journal Article Presentation Book

[Book] 臨床と研究2023
- Author(s)
  松田和暁、木下淳
- Total Pages
  6
- Publisher
  大道学舘出版部
- Data Source
  KAKENHI-PROJECT-21K16826
[Journal Article] Inter-day and intra-day variations in effective intensity of noisy galvanic vestibular stimulation to improve postural stability in bilateral vestibulopathy2023
- Author(s)
  Fujimoto C, Kawahara T, Kinoshita M, Kamogashira T, Oka M, Ichijo K, Koda K, Yamasoba T, Iwasaki S.
- Journal Title
  
  J Vestib Res
  
  Volume: 33 Issue: 6 Pages: 423-429
- DOI
  10.3233/ves-230060
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16826, KAKENHI-PROJECT-21K16853, KAKENHI-PROJECT-23K21476, KAKENHI-PROJECT-23K21478
[Journal Article] Preceding Balance Disorders Affect Vestibular Function in Persistent Postural-Perceptual Dizziness2023
- Author(s)
  Oka Mineko、Ichijo Kentaro、Koda Kento、Kamogashira Teru、Kinoshita Makoto、Igarashi Kazunori、Kawahara Takuya、Takashima Ikumi、Yamasoba Tatsuya、Fujimoto Chisato
- Journal Title
  
  Journal of Clinical Medicine
  
  Volume: 12 Issue: 7 Pages: 2589-2589
- DOI
  10.3390/jcm12072589
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21476, KAKENHI-PROJECT-21K16826, KAKENHI-PROJECT-21K16853
[Journal Article] The effect of self-management vestibular rehabilitation on persistent postural-perceptual dizziness2023
- Author(s)
  Fujimoto C, Oka M, Ichijo K, Kinoshita M, Kamogashira T, Sugasawa K, Kawahara T, Yamasoba T.
- Journal Title
  
  Laryngoscope Investig Otolaryngol
  
  Volume: 8 Issue: 4 Pages: 2589-2589
- DOI
  10.1002/lio2.1073
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16826, KAKENHI-PROJECT-21K16853, KAKENHI-PROJECT-23K21476
[Journal Article] Oral Administration of TrkB Agonist, 7, 8-Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin Induced Vestibular Injury in Guinea Pig2023
- Author(s)
  M Kinoshita, C Fujimoto, S Iwasaki, K Kondo, T Yamasoba
- Journal Title
  
  Pharmaceutics
  
  Volume: 15 (2) Issue: 2 Pages: 493-493
- DOI
  10.3390/pharmaceutics15020493
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K19597, KAKENHI-PROJECT-23K21476, KAKENHI-PROJECT-21K16826, KAKENHI-PROJECT-21K09601, KAKENHI-PROJECT-20H00546, KAKENHI-PROJECT-23K21478
[Journal Article] Analysis of postural stability using foam posturography in patients with persistent postural-perceptual dizziness2023
- Author(s)
  Ichijo K, Oka M, Koda K, Kamogashira T, Kinoshita M, Kawahara T, Takashima I, Demura S, Yamasoba T, Fujimoto C.
- Journal Title
  
  J Vestib Res
  
  Volume: Online ahead of print Issue: 2-3 Pages: 133-144
- DOI
  10.3233/ves-230034
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K16826, KAKENHI-PROJECT-23K21476
[Journal Article] Vestibular Imaging and Function in Patients With Inner Ear Malformation Presenting With Profound Hearing Loss2022
- Author(s)
  Dy Alexander Edward S.、Kashio Akinori、Fujimoto Chisato、Kinoshita Makoto、Kikkawa Yayoi S.、Hoshi Yujiro、Igarashi Kazunori、Uranaka Tsukasa、Iwasaki Shinichi、Yamasoba Tatsuya
- Journal Title
  
  OTO Open
  
  Volume: 6 Issue: 3 Pages: 1-7
- DOI
  10.1177/2473974x221128912
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K09601, KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-23K21476
[Journal Article] Prediction of Vestibular Dysfunction by Applying Machine Learning Algorithms to Postural Instability2020
- Author(s)
  Kamogashira Teru、Fujimoto Chisato、Kinoshita Makoto、Kikkawa Yayoi、Yamasoba Tatsuya、Iwasaki Shinichi
- Journal Title
  
  Frontiers in Neurology
  
  Volume: 11 Pages: 1-1
- DOI
  10.3389/fneur.2020.00007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09369, KAKENHI-PROJECT-18K16906, KAKENHI-PROJECT-17K16895, KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-18K09370
[Journal Article] Acute bilateral vestibulopathy with simultaneous involvement of both superior and inferior vestibular nerves2019
- Author(s)
  Ichijo Kentaro、Kinoshita Makoto、Fujimoto Chisato、Uranaka Tsukasa、Kikkawa Yayoi S.、Sugasawa Keiko、Yamasoba Tatsuya、Iwasaki Shinichi
- Journal Title
  
  Auris Nasus Larynx
  
  Volume: 19 Issue: 5 Pages: 30324-4
- DOI
  10.1016/j.anl.2019.07.007
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-18K09369, KAKENHI-PROJECT-17K16895, KAKENHI-PROJECT-18K09370
[Journal Article] Noisy galvanic vestibular stimulation has a greater ameliorating effect on posture in unstable subjects: a feasibility study2019
- Author(s)
  Fujimoto Chisato、Kinoshita Makoto、Kamogashira Teru、Egami Naoya、Kawahara Takuya、Uemura Yukari、Yamamoto Yoshiharu、Yamasoba Tatsuya、Iwasaki Shinichi
- Journal Title
  
  Scientific Reports
  
  Volume: 9 Issue: 1 Pages: 7-7
- DOI
  10.1038/s41598-019-53834-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09369, KAKENHI-PROJECT-18K09370, KAKENHI-PROJECT-18K16906, KAKENHI-PROJECT-18K17314, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-17K16895
[Journal Article] Alteration of Musashi1 Intra-cellular Distribution During Regeneration Following Gentamicin-Induced Hair Cell Loss in the Guinea Pig Crista Ampullaris2019
- Author(s)
  Kinoshita Makoto、Fujimoto Chisato、Iwasaki Shinichi、Kashio Akinori、Kikkawa Yayoi S.、Kondo Kenji、Okano Hideyuki、Yamasoba Tatsuya
- Journal Title
  
  Frontiers in Cellular Neuroscience
  
  Volume: 13 Pages: 481-481
- DOI
  10.3389/fncel.2019.00481
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09341, KAKENHI-PROJECT-18K09369, KAKENHI-PROJECT-18K09370, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-17K16895
[Journal Article] Progression of Peripheral Vestibular Dysfunctions in Patients With a Mitochondrial A3243G Mutation2019
- Author(s)
  Inoue Aki、Iwasaki Shinichi、Fujimoto Chisato、Kinoshita Makoto、Yamasoba Tatsuya
- Journal Title
  
  Otology & Neurotology
  
  Volume: 40 Issue: 3 Pages: 359-364
- DOI
  10.1097/mao.0000000000002091
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K09369, KAKENHI-INTERNATIONAL-15K21745, KAKENHI-PLANNED-15H05940, KAKENHI-PROJECT-18K09370, KAKENHI-PROJECT-17K16895, KAKENHI-ORGANIZER-15H05935
[Journal Article] Manganese superoxide dismutase influences the extent of noise-induced hearing loss in mice.2017
- Author(s)
  Tuerdi A, Kinoshita M, Kamogashira T, Fujimoto C, Iwasaki S, Shimizu T, Yamasoba T
- Journal Title
  
  Neurosci Lett
  
  Volume: 642 Pages: 123-128
- DOI
  10.1016/j.neulet.2017.02.003
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PUBLICLY-26111506, KAKENHI-PROJECT-26253081, KAKENHI-PROJECT-15H06174, KAKENHI-PROJECT-25293347, KAKENHI-PROJECT-26293165, KAKENHI-PROJECT-26462283, KAKENHI-PROJECT-15K10743, KAKENHI-PROJECT-15K15616
[Presentation] 温度刺激検査とvHITの乖離所見と内耳造影MRI検査における前庭水腫像についての検討2023
- Author(s)
  木下淳、藤本千里、甲田研人、一條研太郎、岡峰子、鴨頭輝、山岨達也
- Organizer
  第82回　日本めまい平衡医学会
- Data Source
  KAKENHI-PROJECT-21K16826
[Presentation] The Contribution of Necroptosis in Gentamicin-induced Hair Cells death in Mice Cochlear Organotypic Cultures2019
- Author(s)
  Gao Ying, Makoto Kinoshita, Shinichi Iwasaki, Akinori Kashio, Yayoi S Kikkawa, Tatsuya Yamasoba.
- Organizer
  第29回日本耳科学会
- Data Source
  KAKENHI-PROJECT-17K16895
[Presentation] 指圧マッサージ施行後にPott’s puffy tumorを呈した1例2019
- Author(s)
  小山美咲、木下淳、堀切教平、岸本めぐみ、菊田周、近藤健二、山岨達也
- Organizer
  第58回日本鼻科学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-17K16895
[Presentation] 両側上下前庭神経系機能の同時障害を認めた急性両側前庭機能障害の一例2019
- Author(s)
  一條研太郎、木下淳、藤本千里、浦中司、吉川弥生、菅澤恵子、岩﨑真一、山岨達也
- Organizer
  第29回日本耳科学会
- Data Source
  KAKENHI-PROJECT-17K16895
[Presentation] メニエール病と遅発性内リンパ水腫における気導cVEMPの周波数特性についての検討2019
- Author(s)
  木下淳、岩﨑真一、竹内成夫、藤本千里、吉川弥生、菅澤恵子、山岨達也
- Organizer
  第78回めまい平衡医学会総会・学術講演会
- Data Source
  KAKENHI-PROJECT-17K16895
[Presentation] 騒音暴露による内耳酸化ストレスがMnSODヘテロ欠損マウスの聴覚に及ぼす影響2016
- Author(s)
  Aynur Turdi、木下淳、藤本千里、岩崎真一、山岨達也
- Organizer
  第16回日本抗加齢医学会総会
- Place of Presentation
  横浜
- Year and Date
  2016-06-10
- Data Source
  KAKENHI-PROJECT-15H06174
[Presentation] Mn-SOD affects Noise Induced Hearing Loss2016
- Author(s)
  Aynur Turdi, Makoto Kinoshita, Chisato Fujimoto, Shinichi Iwasaki, Tatsuya yamasoba
- Organizer
  Association for Research in Otolaryngology, 39th Annual Mid Winter Meeting
- Place of Presentation
  サンディエゴ（USA）
- Year and Date
  2016-02-20
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06174
[Presentation] Mn-SOD affects Noise Induced Hearing Loss2015
- Author(s)
  Ａynur Turdi, Makoto Kinoshita, Chisato Fujimoto, Shinichi Iwasaki, Tatsuya yamasoba
- Organizer
  13th Japan-Taiwan Conference on Otolaryngology-Head and Neck Surgery
- Place of Presentation
  一ツ橋ホール（東京）
- Year and Date
  2015-12-03
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-15H06174

1. 藤本千里 (60581882)

# of Collaborated Projects: 4 results

# of Collaborated Products: 6 results
2. 鴨頭輝 (30807152)

# of Collaborated Projects: 3 results

# of Collaborated Products: 1 results
3. Yamasoba Tatsuya (60251302)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
4. 樫尾明憲 (20451809)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 近藤健二 (40334370)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
6. 岩崎真一 (10359606)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 浦田真次 (60849404)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 松本有 (80548553)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 吉川弥生 (00452350)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
10. 田浦晶子 (70515345)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 柿木章伸 (60243820)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 一條研太郎 (70980382)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 甲田研人 (90961764)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kinoshita Makoto 木下 淳

Research Projects

Research Products

Co-Researchers

Basic research on the effects of various lifestyle guidance recommendations for Meniere's disease on the occurrence of attacksPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Drug delivery treatment for benign paroxysmal positional vertigo

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

メニエール病モデル動物における内耳水代謝関連タンパクの発現変化に関する研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

A study of the role of mitophagy in hearing disorder

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Comprehensive analysis of inner ear pathology by a new imaging technique using a transparent method

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Construction of a new inner ear treatment strategy by orally administrable TrkB agonistPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

Elucidation of the processing mechanism of reactive oxygen species in the inner ear in MnSOD genetically modified animalsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Book] 臨床と研究2023

Author(s)

Total Pages

Publisher

Data Source

[Journal Article] Inter-day and intra-day variations in effective intensity of noisy galvanic vestibular stimulation to improve postural stability in bilateral vestibulopathy2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Preceding Balance Disorders Affect Vestibular Function in Persistent Postural-Perceptual Dizziness2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The effect of self-management vestibular rehabilitation on persistent postural-perceptual dizziness2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Oral Administration of TrkB Agonist, 7, 8-Dihydroxyflavone Regenerates Hair Cells and Restores Function after Gentamicin Induced Vestibular Injury in Guinea Pig2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Analysis of postural stability using foam posturography in patients with persistent postural-perceptual dizziness2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Vestibular Imaging and Function in Patients With Inner Ear Malformation Presenting With Profound Hearing Loss2022

Author(s)

Journal Title

DOI

Kinoshita Makoto 木下淳