KOTAKI TOMOHIRO 小瀧将裕

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KOTAKI Tomohiro 小瀧将裕

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Researcher Number	10758816
Other IDs
Affiliation (Current)	2025: 大阪大学, 微生物病研究所, 助教
Affiliation (based on the past Project Information) *help	2025: 大阪大学, 微生物病研究所, 助教 2021 – 2023: 大阪大学, 微生物病研究所, 助教 2017 – 2020: 神戸大学, 保健学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 49060:Virology-related / Basic Section 90120:Biomaterials-related / Infectious disease medicine
Keywords	Principal Investigator ロタウイルス / ミトコンドリア / viroplasm / 封入体 / 複製機構 / ウイルスベクター / フラビウイルス / RNA / ワクチン / デング熱

Elucidation of the Interaction between Rotavirus and MitochondriaPrincipal Investigator
- Principal Investigator
  
  小瀧将裕
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  The University of Osaka
Analysis of rotavirus replication mechanism with a focus on viroplasmPrincipal Investigator
- Principal Investigator
  
  小瀧将裕
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Osaka University
Development of self-replicable flavivirus vector stably expressing foreign genePrincipal Investigator
- Principal Investigator
  
  Kotaki Tomohiro
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 90120:Biomaterials-related
- Research Institution
  Osaka University
  Kobe University
Development of RNA vaccine against dengue virus infectionPrincipal Investigator
- Principal Investigator
  
  KOTAKI Tomohiro
- Project Period (FY)
  2017 – 2019
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Infectious disease medicine
- Research Institution
  Kobe University

All 2024 2023 2022 2021 2019 2018 2017

All Journal Article Presentation

[Journal Article] Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage2024
- Author(s)
  Minami Shohei、Kotaki Tomohiro、Sakai Yusuke、Okamura Shinya、Torii Shiho、Ono Chikako、Motooka Daisuke、Hamajima Rina、Nouda Ryotaro、Nurdin Jeffery A.、Yamasaki Moeko、Kanai Yuta、Ebina Hirotaka、Maeda Yusuke、Okamoto Toru、Tachibana Taro、Matsuura Yoshiharu、Kobayashi Takeshi
- Journal Title
  
  Microbiology Spectrum
  
  Volume: 12 Issue: 4
- DOI
  10.1128/spectrum.02859-23
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15011, KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739
[Journal Article] Genetic engineering strategy for generating a stable dsRNA virus vector using a virus-like codon-modified transgene2023
- Author(s)
  Kanai Yuta、Onishi Misa、Yoshida Yukino、Kotaki Tomohiro、Minami Shohei、Nouda Ryotaro、Yamasaki Moeko、Enoki Yasutaka、Kobayashi Takeshi
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 10
- DOI
  10.1128/jvi.00492-23
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K15011, KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-23K24376
[Journal Article] Genotype Diversity of Enteric Viruses in Wastewater Amid the COVID-19 Pandemic2023
- Author(s)
  Hoque Sheikh Ariful、Kotaki Tomohiro、Pham Ngan Thi Kim、Onda Yuko、Okitsu Shoko、Sato Shintaro、Yuki Yoshikazu、Kobayashi Takeshi、Maneekarn Niwat、Kiyono Hiroshi、Hayakawa Satoshi、Ushijima Hiroshi
- Journal Title
  
  Food and Environmental Virology
  
  Volume: 15 Issue: 2 Pages: 176-191
- DOI
  10.1007/s12560-023-09553-4
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-23K27420
[Journal Article] Construction of Fosmid-based SARS-CoV-2 replicons for antiviral drug screening and replication analyses in biosafety level 2 facilities2023
- Author(s)
  Takazawa Shunta、Kotaki Tomohiro、Nakamura Satsuki、Utsubo Chie、Kameoka Masanori
- Journal Title
  
  Virus Research
  
  Volume: 334 Pages: 199176-199176
- DOI
  10.1016/j.virusres.2023.199176
- Data Source
  KAKENHI-PROJECT-22K07100
[Journal Article] N-Glycosylation of Rotavirus NSP4 Protein Affects Viral Replication and Pathogenesis.2023
- Author(s)
  Nurdin JA, Kotaki T, Kawagishi T, Sato S, Yamasaki M, Nouda R, Minami S, Kanai Y, Kobayashi T.
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 1
- DOI
  10.1128/jvi.01861-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-21K19379
[Journal Article] The Emergence and Widespread Circulation of Enteric Viruses Throughout the COVID-19 Pandemic: A Wastewater-Based Evidence2023
- Author(s)
  Hoque Sheikh Ariful、Saito Hiroyuki、Akino Wakako、Kotaki Tomohiro、Okitsu Shoko、Onda Yuko、Kobayashi Takeshi、Hossian Tania、Khamrin Pattara、Motomura Kazushi、Maneekarn Niwat、Hayakawa Satoshi、Ushijima Hiroshi
- Journal Title
  
  Food and Environmental Virology
  
  Volume: 15 Issue: 4 Pages: 342-354
- DOI
  10.1007/s12560-023-09566-z
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K10443, KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739
[Journal Article] Effective SARS-CoV-2 replication of monolayers of intestinal epithelial cells differentiated from human induced pluripotent stem cells2023
- Author(s)
  Minami Shohei、Matsumoto Naomi、Omori Hiroko、Nakamura Yutaka、Tamiya Shigeyuki、Nouda Ryotaro、Nurdin Jeffery A.、Yamasaki Moeko、Kotaki Tomohiro、Kanai Yuta、Okamoto Toru、Tachibana Taro、Ushijima Hiroshi、Kobayashi Takeshi、Sato Shintaro
- Journal Title
  
  Scientific Reports
  
  Volume: 13 Issue: 1 Pages: 11610-11610
- DOI
  10.1038/s41598-023-38548-1
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K15011, KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-22K15276, KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-23K27420
[Journal Article] Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis2023
- Author(s)
  Yamasaki Moeko、Kanai Yuta、Wakamura Yoshiki、Kotaki Tomohiro、Minami Shohei、Nouda Ryotaro、Nurdin Jeffery A.、Kobayashi Takeshi
- Journal Title
  
  Journal of Virology
  
  Volume: 97 Issue: 1
- DOI
  10.1128/jvi.01397-22
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07100, KAKENHI-PROJECT-21H02739, KAKENHI-PROJECT-21K19379, KAKENHI-PROJECT-23K24376
[Journal Article] Japanese Encephalitis DNA Vaccines with Epitope Modification Reduce the Induction of Cross-Reactive Antibodies against Dengue Virus and Antibody-Dependent Enhancement of Dengue Virus Infection2022
- Author(s)
  Kotaki Tomohiro、Nagai Yurie、Yamanaka Atsushi、Konishi Eiji、Kameoka Masanori
- Journal Title
  
  Vaccines
  
  Volume: 10 Issue: 9 Pages: 1411-1411
- DOI
  10.3390/vaccines10091411
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K07100
[Journal Article] Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus replicon2022
- Author(s)
  Nakamura A, Kotaki T, Nagai Y, Takazawa S, Tokunaga K, Kameoka M.
- Journal Title
  
  PLoS One
  
  Volume: 17 Issue: 10 Pages: e0274829-e0274829
- DOI
  10.1371/journal.pone.0274829
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07060, KAKENHI-PROJECT-22K07100
[Journal Article] An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency2021
- Author(s)
  Kotaki Tomohiro、Kurosu Takeshi、Grinyo-Escuer Ariadna、Davidson Edgar、Churrotin Siti、Okabayashi Tamaki、Puiprom Orapim、Mulyatno Kris Cahyo、Sucipto Teguh Hari、Doranz Benjamin J.、Ono Ken-ichiro、Soegijanto Soegeng、Kameoka Masanori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 12987-12987
- DOI
  10.1038/s41598-021-92403-9
- NAID
  120007119356
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20200
[Journal Article] A potent neutralizing mouse monoclonal antibody specific to dengue virus type 1 Mochizuki strain recognized a novel epitope around the N-67 glycan on the envelope protein: A possible explanation of dengue virus evolution regarding the acquisition of N-67 glycan2021
- Author(s)
  Kotaki Tomohiro、Yamanaka Atsushi、Konishi Eiji、Kameoka Masanori
- Journal Title
  
  Virus Research
  
  Volume: 294 Pages: 198278-198278
- DOI
  10.1016/j.virusres.2020.198278
- NAID
  120007028999
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K20200
[Journal Article] A PCR amplicon-based SARS-CoV-2 replicon for antiviral evaluation2021
- Author(s)
  Kotaki Tomohiro、Xie Xuping、Shi Pei-Yong、Kameoka Masanori
- Journal Title
  
  Scientific Reports
  
  Volume: 11 Issue: 1 Pages: 2229-2229
- DOI
  10.1038/s41598-021-82055-0
- NAID
  120007119358
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K20200
[Journal Article] Phylogenetic Analysis of Dengue Virus in Bangkalan, Madura Island, East Java Province, Indonesia.2018
- Author(s)
  Teguh Hari Sucipto, Tomohiro Kotaki , Kris Cahyo Mulyatno, Siti Churrotin, Amaliah Labiqah, Soegeng Soegijanto, Masanori Kameoka
- Journal Title
  
  J Trop Med
  
  Volume: 2018 Pages: 6-6
- DOI
  10.1155/2018/8127093
- NAID
  120006425670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16224
[Journal Article] Detection and serotyping of dengue viruses from Aedes aegypti and Aedes albopictus (Diptera: Culicidae) collected in Surabaya, Indonesia 2008 - 20152018
- Author(s)
  Mulyatno KC, Kotaki T, Yotopranoto S, Rohmah EA, Churotin S, Sucipto TH, Amarullah IH, Wardhani P, Soegijanto S, Kameoka M
- Journal Title
  
  Jpn J Infect Dis
  
  Volume: 71 Pages: 58-61
- NAID
  130006317360
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] Development of a Single-Round Infectious Rotavirus as a Next-Generation Vaccine2024
- Author(s)
  Tomohiro Kotaki, Yuta Kanai, Megumi Onishi, Shohei Minami, Chen Zelin, Ryotaro Nouda, Jeffery A. Nurdin, Moeko Yamasaki, Takeshi Kobayashi
- Organizer
  The 1st AMED-SCARDA Joint Symposium on Japan Initiative for World-leading Vaccine Research and Development Center
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] Dissection of the mechanism of rotavirus inclusion body formation with a focus on viral NSP2 protein2024
- Author(s)
  Tomohiro Kotaki, Yuta Kanai, Megumi Onishi, Shohei Minami, Takeshi Kobayashi
- Organizer
  U.S.-Japan Cooperative Medical Sciences Program (USJCMSP) 2024 International Conference on Emerging Infectious Diseases (EID) in the Pacific Rim
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] VP6欠損による一回感染性ロタウイルスの作製2023
- Author(s)
  小瀧将裕、金井祐太、南昌平、大西恵、納田遼太郎、山﨑萌子、小林剛
- Organizer
  第70回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] N-glycosylation of rotavirus NSP4 protein affects viral replication and pathogenesis2022
- Author(s)
  Tomohiro Kotaki, Jeffery A. Nurdin, Takahiro Kawagishi, Shintaro Sato, Moeko Yamasaki, Ryotaro Nouda, Shohei Minami, Yuta Kanai, Takeshi Kobayashi
- Organizer
  14th International dsRNA Virus Symposium
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] ロタウイルスNSP2タンパク質の機能解析2022
- Author(s)
  小瀧将裕, 金井祐太, 南昌平, 納田遼太郎, Jeffery A. Nurdin, 山崎萌子, 小林剛
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] Analysis of the role of rotavirus NSP4 protein in viral replication and pathogenicity2022
- Author(s)
  Tomohiro Kotaki, Jeffery A. Nurdin, Takahiro Kawagishi, Shintaro Sato, Moeko Yamasaki, Ryotaro Nouda, Shohei Minami, Yuta Kanai, Takeshi Kobayashi
- Organizer
  The 20th Awaji International Forum on Infection and Immunity
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] マウス順化サルロタウイルスの作出2022
- Author(s)
  金井祐太, 小瀧将裕, 南昌平, 納田遼太郎, 山﨑萌子, 小林剛
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] ロタウイルス感染に関与する宿主因子Tumor Associated Calcium Signal Transducer 2の機能解析2022
- Author(s)
  山﨑萌子, 金井祐太, 浜島りな, 小瀧将裕, 南昌平, 納田遼太郎, 小林剛
- Organizer
  第69回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-22K07100
[Presentation] Fosmidを用いたSARS-CoV-2レプリコンの構築2021
- Author(s)
  小瀧　将裕, 高澤　駿太, 亀岡　正典
- Organizer
  第68回　日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-20K20200
[Presentation] Evaluation of recombinant anti-dengue neutralizing antibodies that do not cause antibody-dependent enhancement of viral infection2019
- Author(s)
  小瀧将裕、黒須　剛、亀岡正典
- Organizer
  日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] 抗体依存性感染増強を起こさない組換え抗デングウイルス抗体の作製および評価2019
- Author(s)
  小瀧将裕、黒須　剛、亀岡正典
- Organizer
  日本脳炎ウイルス生態学研究会
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] prM領域を改変したデングウイルス2型DNAワクチンの評価2018
- Author(s)
  小瀧将裕、亀岡正典
- Organizer
  第66回日本ウイルス学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] デングウイルスの感染増強を起こさない日本脳炎ワクチンの開発2018
- Author(s)
  小瀧将裕、山中敦史、小西英二、亀岡正典
- Organizer
  第22回日本ワクチン学会学術集会
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] デングウイルスに対する感染増強抗体を誘導しない日本脳炎ワクチンの開発2018
- Author(s)
  小瀧将裕、山中敦史、小西英二、亀岡正典
- Organizer
  第53回日本脳炎ウイルス生態学研究会
- Data Source
  KAKENHI-PROJECT-17K16224
[Presentation] デングウイルス1型EタンパクドメインⅡ上の糖鎖近傍エピトープの解析2017
- Author(s)
  小瀧将裕、山中敦史、小西英二、亀岡正典
- Organizer
  第64回日本ウイルス学会
- Data Source
  KAKENHI-PROJECT-17K16224

1. TOKUNAGA Kenzo

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 南昌平

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
3. 本村和嗣

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

KOTAKI TOMOHIRO 小瀧 将裕

KOTAKI Tomohiro 小瀧 将裕

Research Projects

Research Products

Co-Researchers

Elucidation of the Interaction between Rotavirus and MitochondriaPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of rotavirus replication mechanism with a focus on viroplasmPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of self-replicable flavivirus vector stably expressing foreign genePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of RNA vaccine against dengue virus infectionPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Vero cell-adapted SARS-CoV-2 strain shows increased viral growth through furin-mediated efficient spike cleavage2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genetic engineering strategy for generating a stable dsRNA virus vector using a virus-like codon-modified transgene2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genotype Diversity of Enteric Viruses in Wastewater Amid the COVID-19 Pandemic2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of Fosmid-based SARS-CoV-2 replicons for antiviral drug screening and replication analyses in biosafety level 2 facilities2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] N-Glycosylation of Rotavirus NSP4 Protein Affects Viral Replication and Pathogenesis.2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The Emergence and Widespread Circulation of Enteric Viruses Throughout the COVID-19 Pandemic: A Wastewater-Based Evidence2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effective SARS-CoV-2 replication of monolayers of intestinal epithelial cells differentiated from human induced pluripotent stem cells2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of Sialic Acid-Independent Simian Rotavirus Mutants in Viral Infection and Pathogenesis2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Japanese Encephalitis DNA Vaccines with Epitope Modification Reduce the Induction of Cross-Reactive Antibodies against Dengue Virus and Antibody-Dependent Enhancement of Dengue Virus Infection2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction and evaluation of a self-replicative RNA vaccine against SARS-CoV-2 using yellow fever virus replicon2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] An affinity-matured human monoclonal antibody targeting fusion loop epitope of dengue virus with in vivo therapeutic potency2021

KOTAKI TOMOHIRO 小瀧将裕

KOTAKI Tomohiro 小瀧将裕