Ishizawa Kenichi 石澤健一

Researcher Number	10772684
Other IDs
Affiliation (Current)	2025: 帝京大学, 医学部, 講師
Affiliation (based on the past Project Information) *help	2025: 帝京大学, 医学部, 講師 2019 – 2023: 帝京大学, 医学部, 講師 2017 – 2018: 帝京大学, 医学部, 助手
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related / Kidney internal medicine Except Principal Investigator Basic Section 59040:Nutrition science and health science-related / Basic Section 53040:Nephrology-related / Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
Keywords	Principal Investigator 高血圧 / リン酸化 / KLHL3 / 糖尿病 / 糖尿病性腎症 / カリウム代謝 / NKCC2 / 脱リン酸化 Except Principal Investigator 体液恒常性 / 翻訳後修飾 … More / 食塩感受性 / 腎臓内科学 / 臓器連関 / 代謝異常 / 高血圧 / 尿細管 / 肥満糖尿病 / ユビキチンプロテアソーム / エクソソーム / 慢性腎臓病 / ミネラル代謝 / 食塩感受性高血圧 / 膜輸送体 / 局所制御 / リガンド / ステロイド受容体 / ビタミンD受容体 / pendrin / ミネラルコルチコイド受容体 Less

赤血球・血管内皮・腎尿細管の連関によるカリウム制御機構の解明とヒトへの応用
- Principal Investigator
  
  柴田茂
- Project Period (FY)
  2025 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 59040:Nutrition science and health science-related
- Research Institution
  Teikyo University
臓器連関によるカリウム調節の分子基盤解明と"gut factor"の探索Principal Investigator
- Principal Investigator
  
  石澤健一
- Project Period (FY)
  2023 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Regulation of nuclear receptor through autophagy-related proteins and other mechanisms
- Principal Investigator
  
  Shibata Shigeru
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 54:Internal medicine of the bio-information integration and related fields
- Research Institution
  Teikyo University
Elucidation of the role of the ubiquitin ligase KLHL3 in the pathogenesis of diabetic kidney diseasePrincipal Investigator
- Principal Investigator
  
  Ishizawa Kenichi
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseases
- Principal Investigator
  
  Shibata Shigeru
- Project Period (FY)
  2019 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Teikyo University
Aberrant post-translational modification in diabetic nephropathyPrincipal Investigator
- Principal Investigator
  
  Ishizawa Kenichi
- Project Period (FY)
  2017 – 2018
- Research Category
  
  Grant-in-Aid for Young Scientists (B)
- Research Field
  
  Kidney internal medicine
- Research Institution
  Teikyo University

All 2023 2022 2021 2020 2019 2018 2017

All Journal Article Presentation

[Journal Article] Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism2021
- Author(s)
  Ochiai-Homma F, Kuribayashi-Okuma E, Tsurutani Y, Ishizawa K, Fujii W, Odajima K, Kawagoe M, Tomomitsu Y, Murakawa M, Asakawa S, Hirohama D, Nagura M, Arai S, Yamazaki O, Tamura Y, Fujigaki Y, Nishikawa T, Shibata S
- Journal Title
  
  Hypertens Res
  
  Volume: 44 Issue: 12 Pages: 1557
- DOI
  10.1038/s41440-021-00710-5
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-19K17719
[Journal Article] Role of the ubiquitin proteasome system in the regulation of blood pressure: A review2020
- Author(s)
  Yamazaki Osamu、Hirohama Daigoro、Ishizawa Kenichi、Shibata Shigeru
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Issue: 15 Pages: 1
- DOI
  10.3390/ijms21155358
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-19K17732, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678, KAKENHI-PROJECT-19K22643
[Journal Article] Upregulation of renal Na–K–2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway2020
- Author(s)
  Sakai Kazuhiro、Yamazaki Osamu、Ishizawa Kenichi、Tamura Yoshifuru、Wang Qin、Ueno Masaki、Hayama Yuto、Fujigaki Yoshihide、Shibata Shigeru
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 524 Issue: 3 Pages: 710
- DOI
  10.1016/j.bbrc.2020.01.142
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K22643, KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model2020
- Author(s)
  Wang Qin、Ishizawa Kenichi、Li Jinping、Fujii Wataru、Nemoto Yoshikazu、Yamazaki Osamu、Tamura Yoshifuru、Miura Yutaka、Nie Xuedan、Abe Ryo、Segawa Hiroko、Kuro-O Makoto、Shibata Shigeru
- Journal Title
  
  Communications Biology
  
  Volume: 3 Issue: 1 Pages: 575-575
- DOI
  10.1038/s42003-020-01298-1
- URL
  https://pure.teikyo.jp/en/publications/7532e70c-abd5-4756-9e5a-a53e9d047356
- Language
  English
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19H03678
[Journal Article] Electrolyte transport in the renal collecting duct and its regulation by the renin–angiotensin–aldosterone system2019
- Author(s)
  Yamazaki Osamu、Ishizawa Kenichi、Hirohama Daigoro、Fujita Toshiro、Shibata Shigeru
- Journal Title
  
  Clinical Science
  
  Volume: 133 Issue: 1 Pages: 75
- DOI
  10.1042/cs20180194
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K08201, KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K16074, KAKENHI-PROJECT-17K16097
[Journal Article] Inhibition of sodium glucose cotransporter 2 attenuates the dysregulation of Kelch-like 3 and NaCl cotransporter in obese diabetic mice2019
- Author(s)
  Ishizawa Kenichi、Wang Qin、Li Jinping、Xu Ning、Nemoto Yoshikazu、Morimoto Chikayuki、Fujii Wataru、Tamura Yoshifuru、Fujigaki Yoshihide、Tsukamoto Kazuhisa、Fujita Toshiro、Uchida Shunya、Shibata Shigeru
- Journal Title
  
  Journal of the American Society of Nephrology
  
  Volume: 30 Issue: 5 Pages: 782
- DOI
  10.1681/asn.2018070703
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-19K17719, KAKENHI-PROJECT-19H03678
[Journal Article] ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor2018
- Author(s)
  Shibata Shigeru、Ishizawa Kenichi、Wang Qin、Xu Ning、Fujita Toshiro、Uchida Shunya、Lifton Richard P.
- Journal Title
  
  Cell Reports
  
  Volume: 24 Issue: 3 Pages: 569
- DOI
  10.1016/j.celrep.2018.06.072
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-15H05788, KAKENHI-PROJECT-15H04837, KAKENHI-PROJECT-17K16097
[Presentation] Role of KLHL3-S433 phosphorylation in potassium homeostasis in mice2023
- Author(s)
  Kenichi Ishizawa, Ken Kaseda, Daigoro Hirohama, Osamu Yamazaki, Shigeru Shibata
- Organizer
  American Society of Nephrology, Kidney Week 2023
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K07683
[Presentation] ヒト尿中exosome分画と腎免疫染色におけるユビキチンリガーゼKLHL3リン酸化の検討2022
- Author(s)
  石澤健一, 山崎修, 田村好古, 藤垣嘉秀, 鶴谷悠也, 西川哲男, 柴田茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] ヒト尿中exosome分画と腎免疫染色におけるユビキチンリガーゼKLHL3リン酸化の検討2022
- Author(s)
  石澤健一 , 山崎修 , 田村好古 , 藤垣嘉秀 , 鶴谷悠也 , 西川哲男 , 柴田茂
- Organizer
  第65回　日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17719
[Presentation] Creation and characterization of the ubiquitin ligase KLHL3-S433A knock-in mice2022
- Author(s)
  Kenichi Ishizawa, Ken Kaseda, Osamu Yamazaki, Shigeru Shibata
- Organizer
  The 29th Scientific Meeting of the International Society of Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17719
[Presentation] 原発性アルドステロン症におけるCl/HCO3輸送体pendrinの検討2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、柴田　茂
- Organizer
  日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] 原発性アルドステロン症におけるCl/HCO3輸送体pendrinの検討2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、鶴谷悠也、西川哲男、柴田　茂
- Organizer
  第64回日本腎臓学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism2021
- Author(s)
  Fumika Ochiai-Homma, Emiko Kuribayashi-Okuma, Yuya Tsurutani, Kenichi Ishizawa, Kohei Odajima, Mika Kawagoe, Yoshihiro Tomomitsu, Masataka Murakawa, Shinichiro Asakawa, Daigoro Hirohama, Michito Nagura, Shigeyuki Arai, Osamu Yamazaki, Yoshifuru Tamura, Yoshihide Fujigaki, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  ASN Kidney Week 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] 尿中exosome画分のpendrin発現は原発性アルドステロン症患者のアルドステロン・レニン比と相関し、治療により減弱する2021
- Author(s)
  落合文佳、栗林恵美子、石澤健一、藤井航、浅川信一郎、広浜大五郎、奈倉倫人、新井繁幸、山崎　修、田村好古、藤垣嘉秀、柴田　茂
- Organizer
  第43回日本高血圧学会総会
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Pre- and post-treatment analysis of pendrin in the urinary exosome in primary aldosteronism2020
- Author(s)
  Fumika Ochiai, Emiko Kuribayashi-Okuma, Kenichi Ishizawa, Yuya Tsurutani, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  AHA Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03678
[Presentation] Pre- and post-treatment analysis of pendrin in the urinary exosome in primary aldosteronism2020
- Author(s)
  Fumika Ochiai, Emiko Kuribayashi-Okuma, Kenichi Ishizawa, Yuya Tsurutani, Tetsuo Nishikawa, Shigeru Shibata
- Organizer
  AHA Hypertension
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] Role of vasopressin V2 receptor signaling in NKCC2 regulation in diabetes mellitus・American Society of Nephrology Kidney Week 20192019
- Author(s)
  Kazuhiro Sakai, Osamu Yamazaki, Kenichi Ishizawa, Yoshikazu Nemoto, Shinichiro Asakawa, Michito Nagura, Shigeyuki Arai, Yoshifuru Tamura, Yoshihide Fujigaki, Shigeru Shibata
- Organizer
  American Society of Nephrology Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] Disturbed phosphate metabolism facilitates kidney damage in Dahl salt-sensitive hypertensive rats2019
- Author(s)
  Qin Wang, Kenichi Ishizawa, Yoshikazu Nemoto, Yutaka Miura, Jinping Li, Makoto Kuro-o, Shigeru Shibata
- Organizer
  American Society of Nephrology Kidney Week 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K22643
[Presentation] Dysregulation of the ubiquitin ligase component kelch-like 3 causes Na-Cl cotransporter activation and salt retention in obese diabetic mice2018
- Author(s)
  Kenichi Ishizawa
- Organizer
  Annual meetings of American Society of Nephrology
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16097
[Presentation] Pathogenic role of ubiquitin ligase KLHL3 in diabetic nephropathy2017
- Author(s)
  Kenichi Ishizawa
- Organizer
  AHA Conucil of Hypertension 2017
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K16097

1. Shibata Shigeru (60508068)

# of Collaborated Projects: 4 results

# of Collaborated Products: 10 results
2. 岡崎具樹 (60203973)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 藤垣嘉秀 (20283351)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
4. 諏佐崇生 (20445852)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 田村好古 (10459315)

# of Collaborated Projects: 1 results

# of Collaborated Products: 3 results
6. 山崎修 (80757229)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
7. 月田早智子 (00188517)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 広浜大五郎 (20749353)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 高地雄太 (60415156)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 藤井航 (90786039)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Ishizawa Kenichi 石澤 健一

Research Projects

Research Products

Co-Researchers

赤血球・血管内皮・腎尿細管の連関によるカリウム制御機構の解明とヒトへの応用

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

臓器連関によるカリウム調節の分子基盤解明と"gut factor"の探索Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Regulation of nuclear receptor through autophagy-related proteins and other mechanisms

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the role of the ubiquitin ligase KLHL3 in the pathogenesis of diabetic kidney diseasePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Intra-renal signaling through post-translational modification as the potential target to counteract kidney diseases

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Aberrant post-translational modification in diabetic nephropathyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Research Field

Research Institution

[Journal Article] Characterization of pendrin in urinary extracellular vesicles in a rat model of aldosterone excess and in human primary aldosteronism2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Role of the ubiquitin proteasome system in the regulation of blood pressure: A review2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Upregulation of renal Na–K–2Cl cotransporter 2 in obese diabetes mellitus via a vasopressin receptor 2-dependent pathway2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary phosphate-containing nanoparticle contributes to inflammation and kidney injury in a salt-sensitive hypertension rat model2020

Author(s)

Journal Title

DOI

URL

Language

Data Source

[Journal Article] Electrolyte transport in the renal collecting duct and its regulation by the renin–angiotensin–aldosterone system2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Inhibition of sodium glucose cotransporter 2 attenuates the dysregulation of Kelch-like 3 and NaCl cotransporter in obese diabetic mice2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] ULK1 Phosphorylates and Regulates Mineralocorticoid Receptor2018

Author(s)

Journal Title

DOI

Data Source

[Presentation] Role of KLHL3-S433 phosphorylation in potassium homeostasis in mice2023

Author(s)

Organizer

Ishizawa Kenichi 石澤健一