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MIKI KENJI  三木 健嗣

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三木 健嗣  ミキ ケンジ

Miki Kenji  三木 健嗣

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Researcher Number 10772759
Other IDs
Affiliation (Current) 2025: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任准教授(常勤)
Affiliation (based on the past Project Information) *help 2025: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任講師(常勤)
2023: 大阪大学, ヒューマン・メタバース疾患研究拠点, 特任講師(常勤)
2020: 京都大学, iPS細胞研究所, 研究員
2018 – 2019: 京都大学, iPS細胞研究所, 特定助教
Review Section/Research Field
Principal Investigator
Basic Section 49030:Experimental pathology-related / Basic Section 90110:Biomedical engineering-related / 0702:Biology at cellular to organismal levels, and related fields
Keywords
Principal Investigator
心内膜細胞 / 心筋細胞 / ヒトiPS細胞 / HCM / 心ルーピング / engineered development / 心臓ルーピング / 形態形成 / iPS細胞 / 3D心筋組織 … More / バイオプリンター / 心外膜細胞 / 3Dプリンター / 脱細胞化マトリックス / CRISPR / isogenic iPS細胞 / hiPS細胞 / RNA-seq / MYH7-R719Q / iPS / isogenic / ゲノム編集 / isogenic hiPSC Less
  • Research Projects

    (4 results)
  • Research Products

    (10 results)
  •  マルチモーダルiPS心筋組織評価プラットフォームによる創薬と心機能予測モデルの構築Principal Investigator

    • Principal Investigator
      三木 健嗣
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 90110:Biomedical engineering-related
    • Research Institution
      The University of Osaka
  •  組織工学的アプローチによる心臓形態形成モデルの検証とその応用Principal Investigator

    • Principal Investigator
      三木 健嗣
    • Project Period (FY)
      2023 – 2024
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0702:Biology at cellular to organismal levels, and related fields
    • Research Institution
      Osaka University
  •  Elucidation of the pathogenic mechanism of HCM using isogenic hiPSC-CMs with HCM mutationPrincipal Investigator

    • Principal Investigator
      Miki Kenji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University
  •  Creation of an advanced HCM tissue model using human decellularized native extracellular matrixPrincipal Investigator

    • Principal Investigator
      Miki Kenji
    • Project Period (FY)
      2018 – 2020
    • Research Category
      Fund for the Promotion of Joint International Research (Fostering Joint International Research (A))
    • Review Section
      Basic Section 49030:Experimental pathology-related
    • Research Institution
      Kyoto University

All 2023 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes2021

    • Author(s)
      Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu et al.
    • Journal Title

      Nature Communications

      Volume: in press

    • NAID

      120007089250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0461
  • [Journal Article] Human iPS-derived Pre-epicardial Cells Direct Cardiomyocyte Aggregation, Expansion and Organization In Vitro2021

    • Author(s)
      Jun Jie Tan, Jacques Paul Guyette, Kenji Miki et al.
    • Journal Title

      Nature Communications

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15120
  • [Journal Article] ERRγ enhances cardiac maturation with T-tubule formation in human iPSC-derived cardiomyocytes2021

    • Author(s)
      Kenji Miki, Kohei Deguchi, Misato Nakanishi-Koakutsu et al.
    • Journal Title

      Nature Communications

      Volume: in press

    • NAID

      120007089250

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15120
  • [Journal Article] Human iPS-derived Pre-epicardial Cells Direct Cardiomyocyte Aggregation, Expansion and Organization In Vitro2021

    • Author(s)
      Jun Jie Tan, Jacques Paul Guyette, Kenji Miki et al.
    • Journal Title

      Nature Communications

      Volume: in press

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18KK0461
  • [Presentation] Generation of human iPSC-derived mature cardiomyocytes and its applications2023

    • Author(s)
      Kenji Miki
    • Organizer
      The 5th Monash University - Osaka University Joint Symposium on Advanced Biomedical Sciences
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K19368
  • [Presentation] Differential expression levels of CD151 enable enrichment of atrial cardiomyocytes derived from human induced-pluripotent stem cell2020

    • Author(s)
      Misato Koakutsu, Kenji Miki, Yuki Naka, Masako Sasaki, Stephanie C Napier, Tomoyuki Nishimoto and Yoshinori Yoshida
    • Organizer
      European Society of Cardiology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15120
  • [Presentation] Differential expression levels of CD151 enable enrichment of atrial cardiomyocytes derived from human induced-pluripotent stem cell2020

    • Author(s)
      Misato Koakutsu, Kenji Miki, Yuki Naka, Masako Sasaki, Stephanie C Napier, Tomoyuki Nishimoto, Yoshinori Yoshida
    • Organizer
      European Society of Cardiology Congress
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18KK0461
  • [Presentation] Identification of a Cell Surface Marker which is Differentially Expressed between Ventricular and Atrial Cardiomyocytes Derived from Human Induced-pluripotent Stem Cell2019

    • Author(s)
      Misato Koakutsu, Kenji Miki, Masako Sasaki, Stephanie Napier, Tomoyuki Nishimoto, and Yoshinori Yoshida
    • Organizer
      American Heart Association Scientific Sessions 2019
    • Data Source
      KAKENHI-PROJECT-18K15120
  • [Presentation] Promising small molecules ameliorated morphological abnormalities of hypertrophic cardiomyopathy in iPS cell-derived cardiomyocytes.2019

    • Author(s)
      Kohei Deguchi, Kenji Miki, Shigeru Kondo, Ayaka Sakoda, Tsukasa Sugo, Kenichi Imahashi, Tomoyuki Nishimoto, and Yoshinori Yoshida
    • Organizer
      American Heart Association Scientific Sessions 2019
    • Data Source
      KAKENHI-PROJECT-18K15120
  • [Presentation] ゲノム編集によって作製した疾患iPS心筋細胞を用いた肥大型心筋症治療薬の開発2018

    • Author(s)
      出口康平、三木健嗣、近藤滋、周郷司、西本誠之、吉田善紀
    • Organizer
      第4回心筋症研究会
    • Data Source
      KAKENHI-PROJECT-18K15120

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