Shuzo Kaneko 金子修三

… Alternative Names

KANEKO SYUZO 金子修三

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Researcher Number	10777006
Other IDs
Affiliation (Current)	2025: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Affiliation (based on the past Project Information) *help	2016 – 2024: 国立研究開発法人国立がん研究センター, 研究所, ユニット長
Review Section/Research Field	Principal Investigator Basic Section 62010:Life, health and medical informatics-related / Drug development chemistry Except Principal Investigator Basic Section 56040:Obstetrics and gynecology-related / Basic Section 56010:Neurosurgery-related
Keywords	Principal Investigator エピジェネティクス / スーパーエンハンサー / オミックス解析 / ChIP-seq / エピジェネティックス / ロボティクス / ゲノム解析 / エピゲノム / １細胞解析 / Hi-C … More / 構造多型 / 肺がん / ドライバー遺伝子 / 人工知能 / 機械学習 / 自動化 / シングルセル解析 / 機械学習・深層学習 / ATAC-seq / データマイニング / 分子標的治療薬 / バイオマーカー / 癌 / ヒストンメチル化 / NGS解析 / ヒストン修飾 … More Except Principal Investigator エピゲノム / ロボット / ChIP-seq / マルチオミックス解析 / ロボット技術 / 人工知能 / 卵巣がん / DNA結合モチーフ / 転写因子 / 融合遺伝子 / 上衣腫 / 脳腫瘍 Less

１細胞解析から予測されるスーパーエンハンサー形成における細胞間相互作用の解明Principal Investigator
- Principal Investigator
  
  金子修三
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Cancer Center Japan
Establishment of autonomous epigenetics analysis for clinical applicationPrincipal Investigator
- Principal Investigator
  
  Kaneko Syuzo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Cancer Center Japan
RELA融合遺伝子陽性上衣腫に対する新規治療薬の同定
- Principal Investigator
  
  小澤達也
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56010:Neurosurgery-related
- Research Institution
  National Cancer Center Japan
Next generation epigenomics using artificial intelligence and robotics in ovarian cancer
- Principal Investigator
  
  Komatsu Masaaki
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56040:Obstetrics and gynecology-related
- Research Institution
  Institute of Physical and Chemical Research
Construction of a multilayered integrated epigenetics database based on machine learning and deep learningPrincipal Investigator
- Principal Investigator
  
  Kaneko Syuzo
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 62010:Life, health and medical informatics-related
- Research Institution
  National Cancer Center Japan
Development of new anti-cancer drugs targeted for protein demethylasePrincipal Investigator
- Principal Investigator
  
  KANEKO SYUZO
- Project Period (FY)
  2016 – 2017
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Research Field
  
  Drug development chemistry
- Research Institution
  National Cancer Center Japan

All 2023 2022 2021 2020 2019 2018 2017 Other

All Journal Article Presentation Book Other

[Book] AIが切り拓く未来の医療2020
- Author(s)
  金子修三
- Total Pages
  5
- Publisher
  医歯薬出版株式会社
- Data Source
  KAKENHI-PROJECT-18K11542
[Journal Article] PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway2023
- Author(s)
  Ohata Hirokazu、Shiokawa Daisuke、Sakai Hiroaki、Kanda Yusuke、Okimoto Yoshie、Kaneko Syuzo、Hamamoto Ryuji、Nakagama Hitoshi、Okamoto Koji
- Journal Title
  
  Cell Reports
  
  Volume: 42 Issue: 6 Pages: 112519-112519
- DOI
  10.1016/j.celrep.2023.112519
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07037, KAKENHI-PROJECT-23K07467, KAKENHI-PROJECT-21H03081, KAKENHI-PROJECT-21H03550
[Journal Article] Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses2023
- Author(s)
  Shiraishi Kouya、Takahashi Atsushi、、et al.
- Journal Title
  
  Cancer Communications
  
  Volume: 44 Issue: 2 Pages: 287-293
- DOI
  10.1002/cac2.12498
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K16166, KAKENHI-PROJECT-20K07378, KAKENHI-PROJECT-21K06900, KAKENHI-PROJECT-22K07681, KAKENHI-PROJECT-21K19444, KAKENHI-PROJECT-20K17668, KAKENHI-PROJECT-22H04923, KAKENHI-PROJECT-22H00455, KAKENHI-PROJECT-20H03525, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-23K24602, KAKENHI-PROJECT-23K27389, KAKENHI-PROJECT-23K27506
[Journal Article] Analysis of super-enhancer using machine learning and its application to medical biology2023
- Author(s)
  Hamamoto Ryuji、Takasawa Ken、Shinkai Norio、Machino Hidenori、Kouno Nobuji、Asada Ken、Komatsu Masaaki、Kaneko Syuzo
- Journal Title
  
  Briefings in Bioinformatics
  
  Volume: - Issue: 3
- DOI
  10.1093/bib/bbad107
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519
[Journal Article] Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas2023
- Author(s)
  Machino Hidenori、Dozen Ai、Konaka Mariko、Komatsu Masaaki、Nakamura Kohei、Ikawa Noriko、Shozu Kanto、Asada Ken、Kaneko Syuzo、Yoshida Hiroshi、Kato Tomoyasu、Nakayama Kentaro、Saloura Vassiliki、Kyo Satoru、Hamamoto Ryuji
- Journal Title
  
  Experimental & Molecular Medicine
  
  Volume: 55 Issue: 10 Pages: 2205-2219
- DOI
  10.1038/s12276-023-01090-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03550
[Journal Article] Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability2023
- Author(s)
  Takasawa K, Asada K, Kaneko S, Shiraishi K, Machino H, Takahashi S, Shinkai N, Kouno N, Kobayashi K, Komatsu M, Mizuno T, Okubo Y, Mukai M, Yoshida T, Yoshida Y, Horinouchi H, Watanabe S, Ohe Y, Yatabe Y, Kohno T, Hamamoto R
- Journal Title
  
  Experimental and Molecular Medicine
  
  Volume: 56 Issue: 3 Pages: 646-655
- DOI
  10.1038/s12276-024-01173-7
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-22K07681, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-23K27449
[Journal Article] Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer2022
- Author(s)
  Shozu Kanto、Kaneko Syuzo、Shinkai Norio、Dozen Ai、Kosuge Hirofumi、Nakakido Makoto、Machino Hidenori、Takasawa Ken、Asada Ken、Komatsu Masaaki、Tsumoto Kouhei、Ohnuma Shin-Ichi、Hamamoto Ryuji
- Journal Title
  
  Clinical Epigenetics
  
  Volume: 14 Issue: 1 Pages: 1-13
- DOI
  10.1186/s13148-022-01370-z
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-20H02531, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-22KJ0925
[Journal Article] Introducing AI to the molecular tumor board: one direction toward the establishment of precision medicine using large-scale cancer clinical and biological information2022
- Author(s)
  Hamamoto R, Koyama T, Kouno N, Yasuda T, Yui S, Sudo K, Hirata M, Sunami K, Kubo T, Takasawa K, Takahashi S, Machino H, Kobayashi K, Asada K, Komatsu M, Kaneko S, Yatabe Y, Yamamoto N
- Journal Title
  
  Experimental Biology and Oncology
  
  Volume: 11 Issue: 1 Pages: 8-8
- DOI
  10.1186/s40164-022-00333-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-20H03461, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-23K24468
[Journal Article] Tumor Suppressive Role of the PRELP Gene in Ovarian Clear Cell Carcinoma2022
- Author(s)
  Dozen Ai、Shozu Kanto、Shinkai Norio、Ikawa Noriko、Aoyama Rina、Machino Hidenori、Asada Ken、Yoshida Hiroshi、Kato Tomoyasu、Hamamoto Ryuji、Kaneko Syuzo、Komatsu Masaaki
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 12 Issue: 12 Pages: 1999-1999
- DOI
  10.3390/jpm12121999
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-21H03550
[Journal Article] The metabolic stress-activated checkpoint LKB1-MARK3 axis acts as a tumor suppressor in high-grade serous ovarian carcinoma2022
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Noriko Ikawa, Ken Asada, Ryuichiro Nakato, Kanto Shozu, Ai Dozen, Kenbun Sone, Hiroshi Yoshida, Tomoyasu Kato, Katsutoshi Oda, Yutaka Osuga, Tomoyuki Fujii, Gottfried von Keudell, Vassiliki Saloura, Ryuji Hamamoto
- Journal Title
  
  Communications Biology
  
  Volume: 5 Issue: 1 Pages: 39-39
- DOI
  10.1038/s42003-021-02992-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-21H03550, KAKENHI-PROJECT-21K09466, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03074
[Journal Article] Appkication of non-negative matrix fractorization in oncology: one approach for establishing precision medicine2022
- Author(s)
  Hamamoto R, Takasawa K, Machino H, Kobayashi K, Takahashi S, Bolatkan A, Shinkai N, Sakai A, Aoyama R, Yamada M, Asada K, Komatsu M, Okamoto K, Kameoka H, Kaneko S
- Journal Title
  
  Briefings in Bioinformatics
  
  Volume: 23 Issue: 4
- DOI
  10.1093/bib/bbac246
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K07180, KAKENHI-PROJECT-21K15519, KAKENHI-PROJECT-21H03550
[Journal Article] Integrated Analysis of Whole Genome and Epigenome Data Using Machine Learning Technology: Toward the Establishment of Precision Oncology2021
- Author(s)
  Ken Asada, Syuzo Kaneko, Ken Takasawa, Hidenori Machino, Satoshi Takahashi, Norio Shinkai, Ryo Shimoyama, Masaaki Komatsu, Ryuji Hamamoto
- Journal Title
  
  Frontiers in Oncology
  
  Volume: 11 Pages: 666937-666937
- DOI
  10.3389/fonc.2021.666937
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-21H03550
[Journal Article] C11orf95-RELA fusion drives aberrant gene expression through the unique epigenetic regulation for ependymoma formation2021
- Author(s)
  Ozawa T、Kaneko S、Szulzewsky F、Qiao Z、Takadera M、Narita Y、Kondo T、Holland EC、Hamamoto R、Ichimura K
- Journal Title
  
  Acta Neuropathologica Communications
  
  Volume: 9 Issue: 1 Pages: 36-36
- DOI
  10.1186/s40478-021-01135-4
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09518
[Journal Article] Application of Artificial Intelligence in COVID-19 Diagnosis and Therapeutics2021
- Author(s)
  Asada Ken、Komatsu Masaaki、Shimoyama Ryo、Takasawa Ken、Shinkai Norio、Sakai Akira、Bolatkan Amina、Yamada Masayoshi、Takahashi Satoshi、Machino Hidenori、Kobayashi Kazuma、Kaneko Syuzo、Hamamoto Ryuji
- Journal Title
  
  Journal of Personalized Medicine
  
  Volume: 11 Issue: 9 Pages: 886-886
- DOI
  10.3390/jpm11090886
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03550
[Journal Article] Downregulation of METTL6 mitigates cell progression, migration, invasion and adhesion in hepatocellular carcinoma by inhibiting cell adhesion molecules2021
- Author(s)
  Bolatkan Amina、Asada Ken、Kaneko Syuzo、Suvarna Kruthi、Ikawa Noriko、Machino Hidenori、Komatsu Masaaki、Shiina Shuichiro、Hamamoto Ryuji
- Journal Title
  
  International Journal of Oncology
  
  Volume: 60 Issue: 1 Pages: 4-4
- DOI
  10.3892/ijo.2021.5294
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03550
[Journal Article] Genome-Wide Chromatin Analysis of FFPE Tissues Using a Dual-Arm Robot with Clinical Potential2021
- Author(s)
  Kaneko S、Mitsuyama T、Shiraishi K、Ikawa N、Shozu K、Dozen A、Machino H、Asada K、Komatsu M、Kukita A、Sone K、Yoshida H、Motoi N、Hayami S、Yoneoka Y、Kato T、Kohno T、Natsume T、Keudell GV、Saloura V、Yamaue H、Hamamoto R
- Journal Title
  
  Cancers
  
  Volume: 13 Issue: 9 Pages: 2126-2126
- DOI
  10.3390/cancers13092126
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-20H03820
[Journal Article] Identification of the mutation signature of the cancer genome caused by irradiation2021
- Author(s)
  Kageyama Shun-Ichiro、Du Junyan、Kaneko Syuzo、Hamamoto Ryuji、Yamaguchi Shigeo、Yamashita Riu、Okumura Masayuki、Motegi Atsushi、Hojo Hidehiro、Nakamura Masaki、Tsuchihara Katsuya、Akimoto Tetsuo
- Journal Title
  
  Radiotherapy and Oncology
  
  Volume: 155 Pages: 10-16
- DOI
  10.1016/j.radonc.2020.10.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19K08190, KAKENHI-PROJECT-18K11542
[Journal Article] Epigenetic Mechanisms Underlying COVID-19 Pathogenesis2021
- Author(s)
  Kaneko Syuzo、Takasawa Ken、Asada Ken、Shinkai Norio、Bolatkan Amina、Yamada Masayoshi、Takahashi Satoshi、Machino Hidenori、Kobayashi Kazuma、Komatsu Masaaki、Hamamoto Ryuji
- Journal Title
  
  Biomedicines
  
  Volume: 9 Issue: 9 Pages: 1142-1142
- DOI
  10.3390/biomedicines9091142
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H03550
[Journal Article] Critical Roles of N6-Methyladenosine (m6A) in Cancer and Virus Infection2020
- Author(s)
  Asada Ken、Bolatkan Amina、Takasawa Ken、Komatsu Masaaki、Kaneko Syuzo、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 7 Pages: 1071-1071
- DOI
  10.3390/biom10071071
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-18K05550
[Journal Article] Epigenetic Modifier SETD8 as a Therapeutic Target for High-Grade Serous Ovarian Cancer2020
- Author(s)
  Wada Miku、Kukita Asako、Sone Kenbun、Hamamoto Ryuji、Kaneko Syuzo、Komatsu Masaaki、Takahashi Yu、Inoue Futaba、Kojima Machiko、Honjoh Harunori、Taguchi Ayumi、Kashiyama Tomoko、Miyamoto Yuichiro、Tanikawa Michihiro、Tsuruga Tetsushi、Mori-Uchino Mayuyo、Wada-Hiraike Osamu、Osuga Yutaka、Fujii Tomoyuki
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 12 Pages: 1686-1686
- DOI
  10.3390/biom10121686
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-19K09775, KAKENHI-PROJECT-20H03820, KAKENHI-PROJECT-18K09248, KAKENHI-PROJECT-18K11542
[Journal Article] Two Secreted Proteoglycans, Activators of Urothelial Cell?Cell Adhesion, Negatively Contribute to Bladder Cancer Initiation and Progression2020
- Author(s)
  Papadaki V, Asada K, Watson JK, Tamura T, Leung A, Hopkins J, Dellett M, Sasai N, Davaapil H, Nik-Zainal S, Longbottom R, Nakakido M, Torii R, Veerakumarasivam A, Kaneko S, Sagoo MS, Murphy G, Mitani A, Tsumoto K, Kelly JD, Hamamoto R, Ohnuma SI
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 11 Pages: 3362-3362
- DOI
  10.3390/cancers12113362
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19H03429, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Application of Artificial Intelligence Technology in Oncology: Towards the Establishment of Precision Medicine2020
- Author(s)
  Hamamoto Ryuji、Suvarna Kruthi、Yamada Masayoshi、Kobayashi Kazuma、Shinkai Norio、Miyake Mototaka、Takahashi Masamichi、Jinnai Shunichi、Shimoyama Ryo、Sakai Akira、Takasawa Ken、Bolatkan Amina、Shozu Kanto、Dozen Ai、Machino Hidenori、Takahashi Satoshi、Asada Ken、Komatsu Masaaki、Sese Jun、Kaneko Syuzo
- Journal Title
  
  Cancers
  
  Volume: 12 Issue: 12 Pages: 3532-3532
- DOI
  10.3390/cancers12123532
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K09768, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Predicting Deep Learning Based Multi-Omics Parallel Integration Survival Subtypes in Lung Cancer Using Reverse Phase Protein Array Data2020
- Author(s)
  Takahashi Satoshi、Asada Ken、Takasawa Ken、Shimoyama Ryo、Sakai Akira、Bolatkan Amina、Shinkai Norio、Kobayashi Kazuma、Komatsu Masaaki、Kaneko Syuzo、Sese Jun、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 10 Pages: 1460-1460
- DOI
  10.3390/biom10101460
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17982, KAKENHI-PROJECT-18K05550, KAKENHI-PROJECT-18K11542
[Journal Article] Epigenetics Analysis and Integrated Analysis of Multiomics Data, Including Epigenetic Data, Using Artificial Intelligence in the Era of Precision Medicine2019
- Author(s)
  Hamamoto Ryuji、Komatsu Masaaki、Takasawa Ken、Asada Ken、Kaneko Syuzo
- Journal Title
  
  Biomolecules
  
  Volume: 10 Issue: 1 Pages: 62-62
- DOI
  10.3390/biom10010062
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K09768, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-19H03429
[Journal Article] Deregulation of the Histone Lysine-Specific Demethylase 1 Is Involved in Human Hepatocellular Carcinoma2019
- Author(s)
  Kim Sangchul、Bolatkan Amina、Kaneko Syuzo、Ikawa Noriko、Asada Ken、Komatsu Masaaki、Hayami Shinya、Ojima Hidenori、Abe Nobutsugu、Yamaue Hiroki、Hamamoto Ryuji
- Journal Title
  
  Biomolecules
  
  Volume: 9 Issue: 12 Pages: 810-810
- DOI
  10.3390/biom9120810
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PUBLICLY-18H04908, KAKENHI-PROJECT-17H01580, KAKENHI-PROJECT-19H03429
[Journal Article] Replication stress triggers microsatellite destabilization and hypermutation leading to clonal expansion in vitro2019
- Author(s)
  Matsuno Yusuke、Atsumi Yuko、Shimizu Atsuhiro、Katayama Kotoe、Fujimori Haruka、Hyodo Mai、Minakawa Yusuke、Nakatsu Yoshimichi、Kaneko Syuzo、Hamamoto Ryuji、Shimamura Teppei、Miyano Satoru、Tsuzuki Teruhisa、Hanaoka Fumio、Yoshioka Ken-ichi
- Journal Title
  
  Nature Communications
  
  Volume: 10 Issue: 1 Pages: 3925-3925
- DOI
  10.1038/s41467-019-11760-2
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11542, KAKENHI-PROJECT-19K12215, KAKENHI-PLANNED-15H05912, KAKENHI-PUBLICLY-18H04798, KAKENHI-PUBLICLY-18H04908, KAKENHI-PUBLICLY-19H05210, KAKENHI-PROJECT-19H03429
[Journal Article] Allosteric Activation Dictates PRC2 Activity Independent of Its Recruitment to Chromatin2018
- Author(s)
  Lee Chul-Hwan、Yu Jia-Ray、Kumar Sunil、Jin Ying、LeRoy Gary、Bhanu Natarajan、Kaneko Syuzo、Garcia Benjamin A.、Hamilton Andrew D.、Reinberg Danny
- Journal Title
  
  Molecular Cell
  
  Volume: 70 Issue: 3 Pages: 422-434.e6
- DOI
  10.1016/j.molcel.2018.03.020
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] ゲノムコピー数異常を指標とした創薬標的予測モデルの構築2023
- Author(s)
  金子修三、浜本隆二
- Organizer
  第５回日本メディカルAI学会学術集会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] ゲノムコピー数異常を指標とした創薬標的予測モデルの構築に向けた試み2023
- Author(s)
  金子修三、浜本隆二
- Organizer
  第８２回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] Integrated analysis of ChIP-seq and whole-genome sequencing in lung cancer2022
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  第４回日本メディカルAI学会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] Emerging approaches to the identification of driver mutations in lung cancer2022
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  第81回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] Integrative analysis revealed early epigenetic changes in high-grade serous ovarian carcinogenesis2021
- Author(s)
  Hidenori Machino, Ai Dozen, Masaaki Komatsu, Kohei Nakamura, Kanto Shozu, Syuzo Kaneko, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Kentaro Nakayama, Satoru Kyo, Ryuji Hamamoto
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Large-scale lung cancer ChIP-seq analysis using robots2021
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  日本メディカルAI学会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] Epigenetic and functional analyses of PRELP gene in ovarian cancer2021
- Author(s)
  Masaaki Komatsu, Ai Dozen, Kanto Shozu, Syuzo Kaneko, Hidenori Machino, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Ryuji Hamamoto
- Organizer
  第80回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Large-scale ChIP-seq analysis in pan-negative lung cancer2021
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-21H03550
[Presentation] ロボティクス技術を駆使した大規模クリニカルChIP-seq解析の確立2020
- Author(s)
  金子修三
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Clinical epigenetic analysis with robotics in ovarian cancer.2020
- Author(s)
  Masaaki Komatsu, Syuzo Kaneko, Ken Asada, Hiroshi Yoshida, Tomoyasu Kato, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Biological mechanisms of PRELP in ovarian cancer.2020
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Ken Asada, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] WNT7A gene was regulated by epigenetic changes and associated with tumorigenesis in ovarian clear cell carcinoma.2020
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Tomoyasu Kato, Ryuji Hamamoto.
- Organizer
  第72回日本産科婦人科学会学術講演会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] LKB1-MARK3 axis is a novel stress-activated cell cycle checkpoint and dysregulated in high-grade serous ovarian cancer.2020
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Ken Asada, Ai Dozen, Kanto Shozu, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Integrative multi-omics analysis of multistage carcinogenesis in high-grade serous ovarian cancer.2020
- Author(s)
  Ai Dozen, Masaaki Komatsu, Hidenori Machino, Kohei Nakamura, Syuzo Kaneko, Kanto Shozu, Ken Asada, Tatsuaki Chiyoda, Kentaro Nakayama, Daisuke Aoki, Satoru Kyo, Ryuji Hamamoto.
- Organizer
  第79回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Epigenetic regulation of epithelial cell integrity through extracellular matrix in ovarian cancer2019
- Author(s)
  Ai Dozen, Masaaki Komatsu, Syuzo Kaneko, Kanto Shozu, Hidenori Machino, Tatsuyuki Chiyoda, Daisuke Aoki, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Epigenetic regulation of the WNT7A gene in ovarian clear cell carcinoma2019
- Author(s)
  Kanto Shozu, Masaaki Komatsu, Syuzo Kaneko, Ai Dozen, Hidenori Machino, Akitoshi Nakashima, Shigeru Saito, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] ChIP-seq解析に基づいた“がん”創薬ターゲット探索を加速させるバイオ実験自動化システムの構築2019
- Author(s)
  金子修三
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Tumor suppressive roles of MARK3 in high-grade serous ovarian carcinomas2019
- Author(s)
  Hidenori Machino, Syuzo Kaneko, Masaaki Komatsu, Ai Dozen, Kanto Shozu, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] Toward the application of precision medicine: Multi-omics analysis including clinical ChIP-seq datasets may reveal pivotal regulation of gene expression in cancer2019
- Author(s)
  金子修三
- Organizer
  第2回日本メディカルAI学会学術集会
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Clinical epigenetics using artificial intelligence and robotics in ovarian cancer2019
- Author(s)
  Masaaki Komatsu, Syuzo Kaneko, Ken Asada, Tomoyasu Kato, Ryuji Hamamoto
- Organizer
  第78回日本癌学会学術総会
- Data Source
  KAKENHI-PROJECT-19K09768
[Presentation] 臨床応用を志向したChIP-seq技術に基づいたがんエピゲノム解析の開発2018
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  The 1st Annual Meeting of the Japanese Association for Medical Artificial Intelligence
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Toward precision medicine: developing new toolbox to study the epigenetics applied for cancer treatment2018
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  The 77th Annual Meeting of the Japanese Cancer Association
- Data Source
  KAKENHI-PROJECT-18K11542
[Presentation] Precision Medicineを志向した次世代型のChIP-seq法の開発と今後の展開2017
- Author(s)
  金子修三、浜本隆二
- Organizer
  がん分子標的治療学会
- Data Source
  KAKENHI-PROJECT-16H07461
[Presentation] Toward precision medicine: developing new ChIP-seq techniques applied for cancer treatment2017
- Author(s)
  Syuzo Kaneko and Ryuji Hamamoto
- Organizer
  日本癌学会
- Data Source
  KAKENHI-PROJECT-16H07461
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1. 浜本隆二 (80321800)

# of Collaborated Projects: 2 results

# of Collaborated Products: 27 results
2. Komatsu Masaaki (70750842)

# of Collaborated Projects: 1 results

# of Collaborated Products: 16 results
3. 小澤達也 (80296483)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 浅田健 (70773414)

# of Collaborated Projects: 1 results

# of Collaborated Products: 14 results
5. 塩川大介

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 町野英徳

# of Collaborated Projects: 0 results

# of Collaborated Products: 3 results
7. 北條秀博

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
8. 秋元哲夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
9. 高橋慧

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Shuzo Kaneko 金子 修三

KANEKO SYUZO 金子 修三

Research Projects

Research Products

Co-Researchers

１細胞解析から予測されるスーパーエンハンサー形成における細胞間相互作用の解明Principal Investigator

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Establishment of autonomous epigenetics analysis for clinical applicationPrincipal Investigator

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RELA融合遺伝子陽性上衣腫に対する新規治療薬の同定

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Next generation epigenomics using artificial intelligence and robotics in ovarian cancer

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Construction of a multilayered integrated epigenetics database based on machine learning and deep learningPrincipal Investigator

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Development of new anti-cancer drugs targeted for protein demethylasePrincipal Investigator

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[Book] AIが切り拓く未来の医療2020

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[Journal Article] PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway2023

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[Journal Article] Identification of telomere maintenance gene variations related to lung adenocarcinoma risk by genome‐wide association and whole genome sequencing analyses2023

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[Journal Article] Analysis of super-enhancer using machine learning and its application to medical biology2023

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[Journal Article] Integrative analysis reveals early epigenetic alterations in high-grade serous ovarian carcinomas2023

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[Journal Article] Advances in cancer DNA methylation analysis with methPLIER: use of non-negative matrix factorization and knowledge-based constraints to enhance biological interpretability2023

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[Journal Article] Repression of the PRELP gene is relieved by histone deacetylase inhibitors through acetylation of histone H2B lysine 5 in bladder cancer2022

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[Journal Article] Introducing AI to the molecular tumor board: one direction toward the establishment of precision medicine using large-scale cancer clinical and biological information2022

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Shuzo Kaneko 金子修三

KANEKO SYUZO 金子修三