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NIITSU AI  新津 藍

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Niitsu Ai  新津 藍

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Researcher Number 10791064
Other IDs
Affiliation (Current) 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームディレクター
2025: 国立研究開発法人理化学研究所, 生命機能科学研究センター, 旧チームリーダー
Affiliation (based on the past Project Information) *help 2025: 国立研究開発法人理化学研究所, 生命医科学研究センター, チームディレクター
2023 – 2024: 国立研究開発法人理化学研究所, 生命機能科学研究センター, チームリーダー
2022: 国立研究開発法人理化学研究所, 開拓研究本部, 研究員
2021: 国立研究開発法人理化学研究所, 開拓研究本部, 訪問研究員
2018 – 2020: 国立研究開発法人理化学研究所, 開拓研究本部, 基礎科学特別研究員
2017: 国立研究開発法人理化学研究所, 杉田理論分子科学研究室, 基礎科学特別研究員
Review Section/Research Field
Principal Investigator
Transformative Research Areas, Section (II) / Complex systems / Biophysics
Keywords
Principal Investigator
合成生物学 / 分子動力学 / 分子動力学計算 / 膜タンパク質デザイン / タンパク質デザイン / ペプチド化学 / 蛋白質デザイン / 電気生理 / ペプチドチャネル / タンパク質フォールディング … More / 膜貫通ペプチド / タンパク質設計 / 膜タンパク質設計 / 膜ペプチド Less
  • Research Projects

    (4 results)
  • Research Products

    (26 results)
  • Co-Researchers

    (1 People)
  •  無細胞分子システムで機能する膜貫通タンパク質モジュールの理論設計Principal Investigator

    • Principal Investigator
      新津 藍
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Institute of Physical and Chemical Research
  •  無細胞分子システムを支える汎用膜貫通ペプチドモジュールの理論設計Principal Investigator

    • Principal Investigator
      新津 藍
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Transformative Research Areas (A)
    • Review Section
      Transformative Research Areas, Section (II)
    • Research Institution
      Institute of Physical and Chemical Research
  •  膜電位応答型de novo設計αヘリックスペプチドチャネルの創製と機能の解明Principal Investigator

    • Principal Investigator
      新津 藍
    • Project Period (FY)
      2021 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
    • Review Section
      Complex systems
    • Research Institution
      Institute of Physical and Chemical Research
  •  Folding-mechanism-based design of self-assembling channel peptides aided by molecular dynamics simulationsPrincipal Investigator

    • Principal Investigator
      Niitsu Ai
    • Project Period (FY)
      2017 – 2020
    • Research Category
      Grant-in-Aid for Young Scientists (B)
    • Research Field
      Biophysics
    • Research Institution
      Institute of Physical and Chemical Research

All 2024 2023 2022 2021 2020 2018 2017

All Journal Article Presentation

  • [Journal Article] <i>De novo</i>設計ナノポアの創製2023

    • Author(s)
      新津 藍
    • Journal Title

      Seibutsu-kogaku Kaishi

      Volume: 101 Issue: 8 Pages: 431-434

    • DOI

      10.34565/seibutsukogaku.101.8_431

    • ISSN
      0919-3758, 2435-8630
    • Year and Date
      2023-08-25
    • Language
      Japanese
    • Open Access
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Journal Article] Towards de novo design of transmembrane α-helical assemblies using structural modelling and molecular dynamics simulation2022

    • Author(s)
      Ai Niitsu, Yuji Sugita
    • Journal Title

      Biophys. Rev.

      Volume: 14 Issue: 5 Pages: 1-10

    • DOI

      10.1039/d2cp03972a

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PLANNED-21H05249, KAKENHI-PUBLICLY-22H05438, KAKENHI-PROJECT-19H05645, KAKENHI-PROJECT-21J40162, KAKENHI-PUBLICLY-21H00412
  • [Journal Article] Veratridine binding to a transmembrane helix of sodium channel Nav1.4 determined by solid-state NMR2018

    • Author(s)
      Niitsu Ai、Egawa Ayako、Ikeda Keisuke、Tachibana Kazuo、Fujiwara Toshimichi
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 26 Issue: 21 Pages: 5644-5653

    • DOI

      10.1016/j.bmc.2018.10.012

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Journal Article] 筒形膜タンパク質を基盤とした新規ペプチドポアの設計2018

    • Author(s)
      新津 藍
    • Journal Title

      生物物理

      Volume: 58

    • NAID

      130007420497

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Journal Article] 平面脂質二重膜を用いた単一チャネル電流測定法によるタンパク質・ペプチドポアのキャラクタリゼーション2017

    • Author(s)
      新津 藍
    • Journal Title

      蛋白質科学会アーカイブ

      Volume: 10

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Presentation] 膜ペプチド理論設計による生体分子材料の開発とその動的機能・構造2024

    • Author(s)
      新津 藍
    • Organizer
      日本化学会第104春季年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] Constructing membrane peptide assemblies towards modular protein design2024

    • Author(s)
      Ai Niitsu
    • Organizer
      BDR-IPR joint workshop
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] Characterizing structural dynamics of de novo designed transmembrane peptide barrels2023

    • Author(s)
      Ai Niitsu, Jaewoon Jung, Yuji Sugita
    • Organizer
      EMBL Conference Computational structural biology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] 膜タンパク質を自在につくり理解するために―ペプチドデザインによるア プローチ2023

    • Author(s)
      新津 藍
    • Organizer
      Excells・分子研研究会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] 人工設計ペプチドイオンチャネルの構造ダイナミクス2023

    • Author(s)
      Ai Niitsu, Jaewoon Jung, Yuji Sugita
    • Organizer
      第23回日本蛋白質科学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] 膜貫通ペプチド会合体のde novo設計と機能開拓に向けて2023

    • Author(s)
      新津 藍
    • Organizer
      第17回理研「バイオものづくり」シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] Designed peptide channels and pores: structural stability and dynamics2023

    • Author(s)
      Ai Niitsu
    • Organizer
      IPR-iCeMS joint seminar “Biological Chemistry on Membranes”
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] 膜貫通ペプチド会合体のde novo設計と機能開拓に向けて2023

    • Author(s)
      新津 藍
    • Organizer
      第17回理研「バイオものづくり」シンポジウム
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] De novo design of peptide ion channels2022

    • Author(s)
      A. Niitsu, A.R. Thomson, A.J. Scott, J.T. Sengel, K.R. Mahendran, Y. Sugita, L.R. Brady, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      East Asian Single-Molecule Biophysics Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] Stability and dynamics of de novo designed transmembrane peptide barrels2022

    • Author(s)
      A. Niitsu, J. Jung, and Y. Sugita
    • Organizer
      第60回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] De novo design of peptide ion channels2022

    • Author(s)
      A. Niitsu, A.R. Thomson, A.J. Scott, J.T. Sengel, K.R. Mahendran, Y. Sugita, L.R. Brady, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      East Asian Single-Molecule Biophysics Symposium 2022
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] Stability and dynamics of de novo designed transmembrane peptide barrels2022

    • Author(s)
      A. Niitsu, J. Jung, and Y. Sugita
    • Organizer
      第60回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] De novo design of membrane coiled-coil barrels2022

    • Author(s)
      A. Niitsu, A.R. Thomson, A.J. Scott, J.T. Sengel, K.R. Mahendran, Y. Sugita, L.R. Brady, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      8th Alpbach Workshop coiled-coil, fibrous and repeat proteins
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-22H05438
  • [Presentation] 電位応答性膜ペプチドチャネルの理論設計2022

    • Author(s)
      A. Niitsu, A. R. Thomson, A.J. Scott, J.T. Sengel, Y. Sugita, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      発動分子科学×分子サイバネティクス共催ワークショップ
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] De novo design of membrane coiled-coil barrels2022

    • Author(s)
      A. Niitsu, A.R. Thomson, A.J. Scott, J.T. Sengel, K.R. Mahendran, Y. Sugita, L.R. Brady, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      8th Alpbach Workshop coiled-coil, fibrous and repeat proteins
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] De novo design of transmembrane coiled-coil peptide channels2021

    • Author(s)
      A. Niitsu, A. R. Thomson, A.J. Scott, J.T. Sengel, Y. Sugita, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      第101回日本化学会春季年会
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Presentation] 自己会合する膜貫通ペプチドチャネルの理論設計2021

    • Author(s)
      A. Niitsu, A. R. Thomson, A.J. Scott, J.T. Sengel, Y. Sugita, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      日本物理学会2021年秋季大会
    • Invited
    • Data Source
      KAKENHI-PUBLICLY-21H00412
  • [Presentation] Rational design of membrane-spanning alpha-helical peptide barrels2020

    • Author(s)
      A. Niitsu, A. R. Thomson, A.J. Scott, J.T. Sengel, Y. Sugita, M.I. Wallace, H. Bayley, and D.N. Woolfson
    • Organizer
      第58回日本生物物理学会年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Presentation] Design and characterization of membrane-spanning alpha-helical peptide pores2017

    • Author(s)
      A. Niitsu, K.R. Mahendran, A. R. Thomson, H. Bayley, D.N. Woolfson, Y. Sugita
    • Organizer
      17th annual meeting of Protein Science Society of Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Presentation] Designing autonomous peptide-based membrane pores2017

    • Author(s)
      Niitsu A., Mahendran K.R., Thomson A. R., Session B.R., Sugita Y. Bayley H. and Woolfson D.N
    • Organizer
      Alpbach Workshop coiled-coil, fibrous and repeat proteins
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17K18365
  • [Presentation] Redesign and de novo design of transmembrane alpha-helical peptide barrels2017

    • Author(s)
      Niitsu A., Mahendran K.R., Thomson A. R., Bayley H., Sugita Y. and Woolfson D.N.
    • Organizer
      55th annual meeting of the biophysical society of Japan
    • Invited
    • Data Source
      KAKENHI-PROJECT-17K18365
  • 1.  杉田 有治
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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