Ohta Tomoe 太田智絵

Researcher Number	10804221
Other IDs
Affiliation (Current)	2023: 長崎国際大学, 薬学部, 講師
Affiliation (based on the past Project Information) *help	2021 – 2023: 長崎国際大学, 薬学部, 講師 2018 – 2020: 長崎国際大学, 薬学部, 助教
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords	Principal Investigator 天然物 / 色素異常症 / メラニン / オートファジー / 男性不妊治療 / 精子活性化成分 / 男性不妊症治療 / 天然物化学 / 生薬 / 体外受精 / 男性不妊症 / 精子活性化 … More Except Principal Investigator … More Murraya oenigii / Hibiscus tiliaceus / P-糖タンパク質 / Valeriana fauriei / Hypericum erectum / Petasites japonicus / Lindera umbellata / Wnt シグナル / 創薬 / 天然物 / Wntシグナル経路 / がん幹細胞 / 熱ショックタンパク質 Less

Search for natural products that control from melanin production to the degradation via autophagyPrincipal Investigator
- Principal Investigator
  
  太田智絵
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nagasaki International University
がん化学療法抵抗性改善機能に基づく天然由来新規医薬品シーズの開拓
- Principal Investigator
  
  松本崇宏
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kyoto Pharmaceutical University
Establishment of medicine for male infertility which activate sperm from natural productsPrincipal Investigator
- Principal Investigator
  
  Ohta Tomoe
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Nagasaki International University

All 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Chemical structures and induction of cell death via heat shock protein inhibition of the prenylated phloroglucinol derivatives isolated from Hypericum erectum2022
- Author(s)
  Μatsumoto Takahiro、Imahori Daisuke、Ohnishi Erika、Okayama Masaya、Kitagawa Takahiro、Ohta Tomoe、Yoshida Tatsusada、Kojima Naoto、Yamashita Masayuki、Watanabe Tetsushi
- Journal Title
  
  Fitoterapia
  
  Volume: 156 Pages: 105097-105097
- DOI
  10.1016/j.fitote.2021.105097
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] (+)-Magnolin Enhances Melanogenesis in Melanoma Cells and Three-Dimensional Human Skin Equivalent; Involvement of PKA and p38 MAPK Signaling Pathways2022
- Author(s)
  Uto Takuhiro、Tung Nguyen Huu、Ohta Tomoe、Shoyama Yukihiro
- Journal Title
  
  Planta Medica
  
  Volume: 43 Issue: 13 Pages: 31-39
- DOI
  10.1055/a-1740-7325
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15289
[Journal Article] Construction of sulfur-containing compounds with anti-cancer stem cell activity using thioacrolein derived from garlic based on nature-inspired scaffolds2022
- Author(s)
  Yoneda Taichi、Kojima Naoto、Matsumoto Takahiro、Imahori Daisuke、Ohta Tomoe、Yoshida Tatsusada、Watanabe Tetsushi、Matsuda Hisashi、Nakamura Seikou
- Journal Title
  
  Organic & Biomolecular Chemistry
  
  Volume: 20 Issue: 1 Pages: 196-207
- DOI
  10.1039/d1ob01992a
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567, KAKENHI-PROJECT-20K07109
[Journal Article] Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells2022
- Author(s)
  UTO Takuhiro、OHTA Tomoe、KATAYAMA Koki、SHOYAMA Yukihiro
- Journal Title
  
  Biomed. Res.
  
  Volume: 43 Issue: 2 Pages: 31-39
- DOI
  10.2220/biomedres.43.31
- ISSN
  0388-6107, 1880-313X
- Year and Date
  2022-04-15
- Language
  English
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-21K15289
[Journal Article] Limonoids isolated from the Fortunella crassifolia and the Citrus junos with their cell death-inducing activity on Adriamycin-treated cancer cell2021
- Author(s)
  Kitagawa Takahiro、Matsumoto Takahiro、Imahori Daisuke、Kobayashi Mayuka、Okayama Masaya、Ohta Tomoe、Yoshida Tatsusada、Watanabe Tetsushi
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 75 Issue: 4 Pages: 998-1004
- DOI
  10.1007/s11418-021-01528-8
- NAID
  40022681006
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Effective methods for increasing coumestrol in soybean sprouts2021
- Author(s)
  Ohta Tomoe、Uto Takuhiro、Tanaka Hiromitsu
- Journal Title
  
  PLOS ONE
  
  Volume: 16 Issue: 11 Pages: e0260147-e0260147
- DOI
  10.1371/journal.pone.0260147
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K15289
[Journal Article] Linderapyrone: A Wnt signal inhibitor isolated from Lindera umbellata2021
- Author(s)
  Matsumoto Takahiro、Kitagawa Takahiro、Imahori Daisuke、Matsuzaki Atsushi、Saito Youhei、Ohta Tomoe、Yoshida Tatsusada、Nakayama Yuji、Ashihara Eishi、Watanabe Tetsushi
- Journal Title
  
  Bioorganic & Medicinal Chemistry Letters
  
  Volume: 45 Pages: 128161-128161
- DOI
  10.1016/j.bmcl.2021.128161
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Cell death-inducing activities via P-glycoprotein inhibition of the constituents isolated from fruits of Nandina domestica2021
- Author(s)
  Imahori Daisuke、Μatsumoto Takahiro、Saito Youhei、Ohta Tomoe、Yoshida Tatsusada、Nakayama Yuji、Watanabe Tetsushi
- Journal Title
  
  Fitoterapia
  
  Volume: 154 Pages: 105023-105023
- DOI
  10.1016/j.fitote.2021.105023
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells2020
- Author(s)
  Okubo Shinya、Ohta Tomoe、Shoyama Yukihiro、Uto Takuhiro
- Journal Title
  
  Journal of Natural Medicines
  
  Volume: 74 Issue: 3 Pages: 525-532
- DOI
  10.1007/s11418-020-01396-8
- NAID
  40022252783
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-18K14944
[Journal Article] Chemical structures and cytotoxic activities of the constituents isolated from Hibiscus tiliaceus2020
- Author(s)
  Takahiro Μatsumoto, Daisuke Imahori, Kaduki Achiwa, Youhei Saito, Tomoe Ohta, Tatsusada Yoshida, Naoto Kojima, Masayuki Yamashita, Yuji Nakayama, Tetsushi Watanabe
- Journal Title
  
  Fitoterapia
  
  Volume: 142 Pages: 104524-104524
- DOI
  10.1016/j.fitote.2020.104524
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17K15473, KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Haprin-deficient Spermatozoa Are Incapable of in Vitro Fertilization2020
- Author(s)
  Aoki Y, Tsujimura A, Kaseda K, Okabe M, Tokuhiro K, Ohta T, O'Bryan MK, Okuda H, Kitamura K, Ogawa Y, Fujiki T, Wada M, Horie S, Nishimune Y, Tanaka H.
- Journal Title
  
  Mol. Reprod. Dev.
  
  Volume: 87（5） Issue: 5 Pages: 534-541
- DOI
  10.1002/mrd.23344
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K07458, KAKENHI-PROJECT-18K14944
[Journal Article] Cytotoxic activities of sesquiterpenoids from the aerial parts of Petasites japonicus against cancer stem cells.2020
- Author(s)
  Takahiro Matsumoto, Daisuke Imahori, Youhei Saito, Wei Zhang, Tomoe Ohta, Tatsusada Yoshida, Yuji Nakayama, Eishi Ashihara, Tetsushi Watanabe
- Journal Title
  
  J. Nat. Med.
  
  Volume: 74 Issue: 4 Pages: 689-701
- DOI
  10.1007/s11418-020-01420-x
- NAID
  40022344636
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-19K08826, KAKENHI-PROJECT-20H03397, KAKENHI-PROJECT-20J14567
[Journal Article] Establishment of a quantitative and qualitative analysis and isolation method for tetracyclic iridoids from Morinda lucida Bentham leaves2019
- Author(s)
  Ohta Tomoe、Tilkanont Tanatorn、Ayertey Frederick、Nakagawa Mina、Tung Nguyen Huu、Bolah Peter、Blagogee Heron、Appiah Alfred Ampomah、Ocloo Augustine、Ohashi Mitsuko、Tanoue Kensuke、Yamaguchi Yasuchika、Ohta Nobuo、Yamaoka Shoji、Iwanaga Shiro、Uto Takuhiro、Shoyama Yukihiro
- Journal Title
  
  Journal of Pharmaceutical and Biomedical Analysis
  
  Volume: 164 Pages: 475-480
- DOI
  10.1016/j.jpba.2018.10.044
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K14944, KAKENHI-PROJECT-17H04071, KAKENHI-PROJECT-16K15264
[Presentation] 抗がん剤抵抗性の改善を目指した新規プレニル化フロログルシノールのHsp105阻害活性評価2022
- Author(s)
  松本崇宏, 大西英里加, 岡山真也, 今堀大輔, 太田智絵, 吉田達貞, 小島直人, 山下正行, 渡辺徹志
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03397
[Presentation] カノコソウ (Valeriana fauriei) より得られた新規化合物の化学構造およびがん幹細胞に与える影響2022
- Author(s)
  岡山真也, 松本崇宏, 吉川勇人, 今堀大輔, 太田智絵, 吉田達貞, 渡辺徹志
- Organizer
  日本薬学会第142年会
- Data Source
  KAKENHI-PROJECT-20H03397
[Presentation] クロモジ含有成分 linderapyrone の化学構造，合成，および wnt /β-catenin 経路阻害活性評価2021
- Author(s)
  松本崇宏, 北川翔大, 今堀大輔, 太田智絵, 吉田達貞, 芦原英司, 渡辺徹志
- Organizer
  日本生薬学会第67回年会
- Data Source
  KAKENHI-PROJECT-20H03397
[Presentation] 抗原虫活性を有するテトラサイクリックイリドイド類の効率的かつ簡易な単離方法の開発2019
- Author(s)
  中川未菜，太田智絵，Frederick Ayertey，Tanatorn Tilkanont，Alfred Appiah，Augustine Ocloo，大橋光子，山岡昇司，太田伸生，岩永史郎，宇都拓洋，正山征洋
- Organizer
  日本薬学会第139年会
- Data Source
  KAKENHI-PROJECT-18K14944
[Presentation] ガーナ薬用植物 Morinda lucida に含有する成分の精子活性化作用2019
- Author(s)
  太田智絵、正山征洋、宇都拓洋、田中宏光
- Organizer
  第3回食薬ヘルスイノベーション研究会
- Data Source
  KAKENHI-PROJECT-18K14944
[Presentation] 顧みられない熱帯病に有効なMorinda lucidaに含有する新規イリドイド化合物の分析2018
- Author(s)
  太田智絵，Tanatorn Tilkanont，Nguyen Huu Tung, Frederick Ayertey，田上兼輔，Alfred A. Appiah，Augustine Ocloo，大橋光子，宇都拓洋，山口泰史，岩永史郎，太田伸生，正山征洋
- Organizer
  第2回食薬ヘルスイノベーション研究会
- Data Source
  KAKENHI-PROJECT-18K14944
[Presentation] ガーナ産植物Morinda lucida Benthamに含まれる新規テトラサイクリックイリドイドの化学構造2018
- Author(s)
  太田智絵, Nguyen Huu Tung, 吉田達貞, 宇都拓洋, Augustine Ocloo, 大橋光子, 岩永史郎, 山岡昇司, 太田伸生, 正山征洋
- Organizer
  第35回日本薬学会九州支部大会
- Data Source
  KAKENHI-PROJECT-18K14944

1. 松本崇宏 (30780431)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 中村誠宏 (20411035)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
3. 渡部匡史 (60634326)

# of Collaborated Projects: 1 results

# of Collaborated Products: 5 results
4. 渡辺徹志 (90182930)

# of Collaborated Projects: 1 results

# of Collaborated Products: 8 results
5. 齊藤洋平 (90411032)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
6. 小川由起子

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
7. 芦原英司

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Ohta Tomoe 太田 智絵

Research Projects

Research Products

Co-Researchers

Search for natural products that control from melanin production to the degradation via autophagyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

がん化学療法抵抗性改善機能に基づく天然由来新規医薬品シーズの開拓

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of medicine for male infertility which activate sperm from natural productsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Chemical structures and induction of cell death via heat shock protein inhibition of the prenylated phloroglucinol derivatives isolated from Hypericum erectum2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] (+)-Magnolin Enhances Melanogenesis in Melanoma Cells and Three-Dimensional Human Skin Equivalent; Involvement of PKA and p38 MAPK Signaling Pathways2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Construction of sulfur-containing compounds with anti-cancer stem cell activity using thioacrolein derived from garlic based on nature-inspired scaffolds2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Silibinin promotes melanogenesis through the PKA and p38 MAPK signaling pathways in melanoma cells2022

Author(s)

Journal Title

DOI

ISSN

Year and Date

Language

Data Source

[Journal Article] Limonoids isolated from the Fortunella crassifolia and the Citrus junos with their cell death-inducing activity on Adriamycin-treated cancer cell2021

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Effective methods for increasing coumestrol in soybean sprouts2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Linderapyrone: A Wnt signal inhibitor isolated from Lindera umbellata2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cell death-inducing activities via P-glycoprotein inhibition of the constituents isolated from fruits of Nandina domestica2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Arctigenin suppresses cell proliferation via autophagy inhibition in hepatocellular carcinoma cells2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Chemical structures and cytotoxic activities of the constituents isolated from Hibiscus tiliaceus2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Haprin-deficient Spermatozoa Are Incapable of in Vitro Fertilization2020

Author(s)

Journal Title

Ohta Tomoe 太田智絵