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Kimura Kimitoshi  木村 公俊

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木村 公俊  キムラ キミトシ

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Researcher Number 10807093
Other IDs
Affiliation (Current) 2023: 京都大学, 医学研究科, 特定助教
2023: 国立研究開発法人国立精神・神経医療研究センター, 神経研究所 免疫研究部, 客員研究員
Affiliation (based on the past Project Information) *help 2023: 京都大学, 医学研究科, 医員
2018 – 2019: 京都大学, 医学研究科, 特定病院助教
Review Section/Research Field
Principal Investigator
Basic Section 52020:Neurology-related
Keywords
Principal Investigator
miRNA / エクソソーム / 個別化治療 / バイオマーカー / 自己抗体 / B細胞 / T細胞 / 血液浄化療法 / CD11c+ B細胞 / Th1細胞 / 個別化医療 / 多発性硬化症
  • Research Projects

    (1 results)
  • Research Products

    (17 results)
  •  Development of novel therapeutic approach and realization of personalized medicine in multiple sclerosisPrincipal Investigator

    • Principal Investigator
      木村 公俊
    • Project Period (FY)
      2022 – 2023
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 52020:Neurology-related
    • Research Institution
      Kyoto University

All 2019 2018

All Journal Article Presentation Patent

  • [Journal Article] Clinical characteristics of autoimmune disorders in the central nervous system associated with myasthenia gravis2019

    • Author(s)
      Kimura Kimitoshi、Okada Yoichiro、Fujii Chihiro、Komatsu Kenichi、Takahashi Ryosuke、Matsumoto Sadayuki、Kondo Takayuki
    • Journal Title

      Journal of Neurology

      Volume: 266 Issue: 11 Pages: 2743-2751

    • DOI

      10.1007/s00415-019-09461-3

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] 多発性硬化症と制御性T細胞2019

    • Author(s)
      山村隆、木村公俊
    • Journal Title

      医学のあゆみ

      Volume: 268 Pages: 1229-1233

    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] The Role for Exosomal microRNAs in Disruption of Regulatory T Cell Homeostasis in Multiple Sclerosis2018

    • Author(s)
      Kimura Kimitoshi、Hohjoh Hirohiko、Yamamura Takashi
    • Journal Title

      Journal of Experimental Neuroscience

      Volume: 12 Pages: 117906951876489-117906951876489

    • DOI

      10.1177/1179069518764892

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] 多発性硬化症において循環血中のエクソソームはlet-7i を介して制御性T細胞の分化を抑制する2018

    • Author(s)
      木村公俊、北條浩彦、山村隆
    • Journal Title

      臨床免疫・アレルギー科

      Volume: 70 Pages: 129-135

    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] 多発性硬化症2018

    • Author(s)
      木村公俊、山村隆
    • Journal Title

      Progress in Medicine

      Volume: 38 Pages: 1311-1317

    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] 多発性硬化症において、血中のエクソソームが制御性T細胞の分化を抑制する2018

    • Author(s)
      木村公俊、北條浩彦、山村隆
    • Journal Title

      実験医学

      Volume: 36 Pages: 1497-1500

    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Journal Article] Circulating exosomes cause loss of immunological balance in multiple sclerosis2018

    • Author(s)
      Kimura Kimitoshi、Yamamura Takashi
    • Journal Title

      Clinical and Experimental Neuroimmunology

      Volume: 9 Issue: 4 Pages: 209-210

    • DOI

      10.1111/cen3.12474

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Patent] 血液浄化療法の臨床的有効性を予測するためのデータを収集する方法2018

    • Inventor(s)
      木村公俊、林幼偉、山村隆
    • Industrial Property Rights Holder
      国立精神・神経医療研究センター
    • Industrial Property Rights Type
      特許
    • Industrial Property Number
      2018-155801
    • Filing Date
      2018
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] マイクロRNAを介したエクソソームによる多発性硬化症の病態2019

    • Author(s)
      木村公俊
    • Organizer
      第3回Liquid Biopsy研究会
    • Invited
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] Response to Plasmapheresis is Predicted by the Th1 Cell Frequency in the Blood in Multiple Sclerosis2019

    • Author(s)
      Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
    • Organizer
      Federation of Clinical Immunology Societies Annual Meeting 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] Clinical and immunological efficacy of plasmapheresis in MS and NMO refractory to steroid pulse therapy2019

    • Author(s)
      Youwei Lin, Kimitoshi Kimura, Yoko Yamada, Wakiro Sato, Manabu Araki, Tomoko Okamoto, Seiichi Yasuda, Takashi Yamamura, Yuji Takahashi
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] Th1 cell frequency is an accurate predictor of responders to plasmapheresis in multiple sclerosis2019

    • Author(s)
      Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
    • Organizer
      第60回日本神経学会学術大会
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] ステロイドパルス療法で寛解不充分なMS・NMOにおける血液浄化療法の有効性と免疫学的指標2019

    • Author(s)
      林 幼偉、木村 公俊、坪田 佳代子、佐藤 和貴朗、荒木 学、岡本 智子、登坂 一眞、安田 聖一、山村 隆、高橋 祐二
    • Organizer
      第31回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] The efficacy of plasmapheresis for multiple sclerosis and neuromyelitis optica unresponsive to steroid-pulse therapy and its immunological prognostic markers2019

    • Author(s)
      Youwei Lin, Kimitoshi Kimura, Kayoko Tsubota, Wakiro Sato, Manabu Araki, Tomoko Okamoto, Kazuma Tosaka, Seiichi Yasuda, Takashi Yamamura, Yuji Takahashi
    • Organizer
      The Joint meeting of the 12th World Congress of International Society for Apheresis and the 40th Annual Meeting of Japanease Society for Apheresis
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] 多発性硬化症におけるmiRNAを介したエクソソームの関与2018

    • Author(s)
      木村公俊
    • Organizer
      東京農工大学-国立精神・神経医療研究センター 第4回合同シンポジウム
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] Successful response to plasmapheresis is mediated by phenotypic change of Th1 cells in multiple sclerosis2018

    • Author(s)
      Kimitoshi Kimura, Youwei Lin, Wakiro Sato, Ryosuke Takahashi, Takashi Yamamura
    • Organizer
      14th International Congress of Neuroimmunology
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15473
  • [Presentation] 多発性硬化症への免疫吸着療法における、T細胞解析に基づいた個別化医療実現と作用機序解明2018

    • Author(s)
      木村公俊、林幼偉、佐藤和貴郎、髙橋良輔、山村隆
    • Organizer
      第30回日本神経免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-18K15473

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