Nozawa Kayo 野澤佳世

Researcher Number	10808554
Other IDs	https://orcid.org/0000-0001-6677-7195
Affiliation (Current)	2026: 東京科学大学, 生命理工学院, 准教授
Affiliation (based on the past Project Information) *help	2024: 東京科学大学, 生命理工学院, 准教授 2021 – 2023: 東京工業大学, 生命理工学院, 准教授 2018 – 2021: 東京大学, 定量生命科学研究所, 助教
Review Section/Research Field	Principal Investigator Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related / Basic Section 45020:Evolutionary biology-related / Basic Section 45010:Genetics-related / Transformative Research Areas, Section (III) / Basic Section 43050:Genome biology-related / 0701:Biology at molecular to cellular levels, and related fields Except Principal Investigator Transformative Research Areas, Section (III)
Keywords	Principal Investigator クライオ電子顕微鏡解析 / 転写 / クロマチン / ゲノム解析 / サブヌクレオソーム / RNAポリメラーゼII / メガダルトン複合体 / 遺伝子発現制御 / クロマチン構造 / RNAポリメラーゼ … More Except Principal Investigator … More 計算化学 / メガ生命深化動態 / メガ深化 / 計算科学 / 人工細胞研究 / 構造生命科学 / 構造生命システム科学 / メガダルトン Less

Structural and in-cell functional analysis of H3-H4 octosomePrincipal Investigator
- Principal Investigator
  
  野澤佳世
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 45010:Genetics-related
  Basic Section 45020:Evolutionary biology-related
  Sections That Are Subject to Joint Review: Basic Section45010:Genetics-related ,Basic Section45020:Evolutionary biology-related
- Research Institution
  Institute of Science Tokyo
Autonomous biological systems of megadalton complexity
- Principal Investigator
  
  Tsukazaki Tomoya
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Nara Institute of Science and Technology
Structural analysis of megadalton complexes in the dynamic genomePrincipal Investigator
- Principal Investigator
  
  Nozawa Kayo
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Transformative Research Areas (B)
- Review Section
  
  Transformative Research Areas, Section (III)
- Research Institution
  Tokyo Institute of Technology
Structural and functional analysis of the novel chromatin unitPrincipal Investigator
- Principal Investigator
  
  Nozawa Kayo
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 43050:Genome biology-related
- Research Institution
  Tokyo Institute of Technology
  The University of Tokyo
Structural bases of transcriptional regulation by chromatin conformationPrincipal Investigator
- Principal Investigator
  
  Nozawa Kayo
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0701:Biology at molecular to cellular levels, and related fields
- Research Institution
  The University of Tokyo

All 2025 2024 2023 2022 2021 2019 2018

All Journal Article Presentation

[Journal Article] Cryo-EM Analysis of a Unique Subnucleosome Containing Centromere-Specific Histone Variant CENP-A.2025
- Author(s)
  Kawasaki O, Takizawa Y, Kiyokawa I, Kurumizaka H, Nozawa K.
- Journal Title
  
  Genes Cells.
  
  Volume: - Issue: 2
- DOI
  10.1111/gtc.70016
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24H02328, KAKENHI-PROJECT-23H05475, KAKENHI-PROJECT-23K27211
[Journal Article] Asymmetric fluctuation of overlapping dinucleosome studied by cryoelectron microscopy and small-angle X-ray scattering.2024
- Author(s)
  Shimizu M, Tanaka H, Nishimura M, Sato N, Nozawa K, Ehara H, Sekine SI, Morishima K, Inoue R, Takizawa Y, Kurumizaka H, Sugiyama M.
- Journal Title
  
  PNAS Nexus.
  
  Volume: 3 Issue: 11
- DOI
  10.1093/pnasnexus/pgae484
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-24H02328, KAKENHI-PROJECT-23H05475, KAKENHI-PROJECT-23K27211, KAKENHI-PROJECT-24K18081
[Journal Article] Genome-wide mapping and cryo-EM structural analyses of the overlapping tri-nucleosome composed of hexasome-hexasome-octasome moieties2024
- Author(s)
  Nishimura Masahiro、Fujii Takeru、Tanaka Hiroki、Maehara Kazumitsu、Morishima Ken、Shimizu Masahiro、Kobayashi Yuki、Nozawa Kayo、Takizawa Yoshimasa、Sugiyama Masaaki、Ohkawa Yasuyuki、Kurumizaka Hitoshi
- Journal Title
  
  Communications Biology
  
  Volume: 7 Issue: 1 Pages: 61-61
- DOI
  10.1038/s42003-023-05694-1
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22KJ2462, KAKENHI-PROJECT-22K06098, KAKENHI-PROJECT-22K19275, KAKENHI-PUBLICLY-22H04676, KAKENHI-PUBLICLY-22H04696, KAKENHI-PROJECT-23H00372, KAKENHI-PROJECT-23K27211, KAKENHI-PUBLICLY-23H04288
[Journal Article] Structural basis for p53 binding to its nucleosomal target DNA sequence2022
- Author(s)
  Nishimura Masahiro、Takizawa Yoshimasa、Nozawa Kayo、Kurumizaka Hitoshi
- Journal Title
  
  PNAS Nexus
  
  Volume: 1 Issue: 4
- DOI
  10.1093/pnasnexus/pgac177
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K06098, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-20K06599, KAKENHI-PLANNED-21H05154, KAKENHI-PLANNED-18H05534
[Journal Article] Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B2022
- Author(s)
  Nozawa Kayo、Takizawa Yoshimasa、Pierrakeas Leonidas、Sogawa-Fujiwara Chizuru、Saikusa Kazumi、Akashi Satoko、Luk Ed、Kurumizaka Hitoshi
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 119 Issue: 45
- DOI
  10.1073/pnas.2206542119
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K06098, KAKENHI-PROJECT-20H00449, KAKENHI-PROJECT-20K06599, KAKENHI-PLANNED-21H05154, KAKENHI-PLANNED-18H05534, KAKENHI-PLANNED-19H05774
[Journal Article] Cryo-electron microscopy structure of the H3-H4 octasome without histones H2A and H2B2021
- Author(s)
  K, Nozawa., Y, Takizawa., L, Pierrakeas., K, Saikusa., S Akashi., E, Luk., H, Kurumizaka.
- Journal Title
  
  bioRxiv
  
  Volume: -
- DOI
  10.1101/2021.10.27.466091
- Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06599
[Journal Article] Crystallographic analysis of the overlapping dinucleosome as a novel chromatin unit2018
- Author(s)
  Nishimura Masahiro、Nozawa Kayo、Kurumizaka Hitoshi
- Journal Title
  
  Biophysics and Physicobiology
  
  Volume: 15 Issue: 0 Pages: 251-254
- DOI
  10.2142/biophysico.15.0_251
- NAID
  130007535611
- ISSN
  2189-4779
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-18H05534, KAKENHI-PROJECT-19K21175
[Presentation] Structural and biochemical analysis of a unique structural unit of chromatin2024
- Author(s)
  Kayo Nozawa, Hitoshi Kurumizaka
- Organizer
  21st IUPAB (International Union for Pure and Applied Biophysics) and 62nd BSJ (The Biophysical Society of Japan) JOINT CONGRESS 2024
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] ユニークなゲノム基盤構造であるH3-H4オクタソームの構造機能解析2024
- Author(s)
  野澤佳世
- Organizer
  日本遺伝学会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] Structural and functional analysis of a unique subnucleosome involved in centromere formation2024
- Author(s)
  Iori Kiyokawa, Hitoshi Kurumizaka, Kayo Nozawa
- Organizer
  21st IUPAB (International Union for Pure and Applied Biophysics) and 62nd BSJ (The Biophysical Society of Japan) JOINT CONGRESS 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] Extraction of histone H3-H4-enriched chromatin from eukaryotic cells and observation of its structure by cryo-electron microscopy2024
- Author(s)
  Osamu Kawasaki, Hitoshi Kurumizaka, Kayo Nozawa
- Organizer
  21st IUPAB (International Union for Pure and Applied Biophysics) and 62nd BSJ (The Biophysical Society of Japan) JOINT CONGRESS 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] 原子の世界をのぞく技術でゲノム構造を見る！2024
- Author(s)
  野澤佳世
- Organizer
  国際メンタリングワークショップJoshikai in Fukushima 2024
- Invited
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] Structural and functional analysis of reconstituted chromatin encapsulated in artificial cells2023
- Author(s)
  Gen Kumakura, Yutetsu Kuruma, Kayo Nozawa
- Organizer
  "Structure, Function and Dynamics" international conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] Functional and structural analysis of nucleosome transcription by RNAPII with cohesin/Scc2 loading complex2023
- Author(s)
  Ryunosuke Odaka, Yasuto Murayama, Kayo Nozawa
- Organizer
  "Structure, Function and Dynamics" international conference
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] ヒストンH2AとH2Bを含まないユニークなサブヌクレオソームの構造機能解析2023
- Author(s)
  野澤佳世
- Organizer
  第46回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] Cryo-electron microscopic analysis reveal a nucleosome-like particle without histones H2A and H2B, H3-H4 octasome2023
- Author(s)
  Kayo Nozawa, Yoshimasa Takizawa, Leonidas Pierrakeas, Chizuru Sogawa-Fujiwara, Kazumi Saikusa, Satoko Akashi, Ed Luk, Hitoshi Kurumizaka
- Organizer
  Chromatin Architecture: Structure and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] Cryo-electron microscopic analysis reveal a nucleosome-like particle without histones H2A and H2B, H3-H4 octasome2023
- Author(s)
  Kayo Nozawa
- Organizer
  International Symposium on Chromatin Architecture: Structure and Function
- Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] Cryo-electron microscopic analysis reveal a nucleosome-like particle without histones H2A and H2B2023
- Author(s)
  Kayo Nozawa
- Organizer
  Structure, Function and Dynamics International Conference
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] Functional and structural analysis reveal a nucleosome-like particle without histones H2A and H2B2023
- Author(s)
  Kayo Nozawa
- Organizer
  第61回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-23K27211
[Presentation] 遺伝子発現を制御する超分子複合体の構造機能解析2023
- Author(s)
  野澤佳世
- Organizer
  RNAフロンティアミーティング2023
- Invited
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] 新しいクロマチン基盤構造H3-H4オクタソームのクライオ電子顕微鏡解析2022
- Author(s)
  野澤佳世、滝沢由政、七種和美、明石知子、胡桃坂仁志
- Organizer
  第22回日本蛋白質科学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] 遺伝子発現を制御するゲノム構造の試験管内再構成技術電子顕微鏡解析2022
- Author(s)
  野澤佳世、胡桃坂仁志
- Organizer
  「細胞を創る」研究会 15.0
- Invited
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] ゲノム三次構造が遺伝子発現に与える影響2022
- Author(s)
  野澤佳世、胡桃坂仁志
- Organizer
  第22回日本蛋白質科学会年会
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] Structural and biochemical analysis of a novel structural unit of chromatin2022
- Author(s)
  Kayo Nozawa
- Organizer
  Panelist for 20th Surugaidai International Symposium & Joint Usage/Research Program of Medical Research Institute Symposium
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] 新しいクロマチン基盤ユニットであるH3-H4オクタソームのクライオ電子顕微鏡解析2022
- Author(s)
  野澤佳世、滝沢由政、七種和美、明石知子、胡桃坂仁志
- Organizer
  第60回生物物理年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] クライオ電子顕微鏡解析から明らかになった新しいサブヌクレオソーム・H3-H4オクタソームの構造機能解析2022
- Author(s)
  野澤佳世
- Organizer
  第45回日本分子生物学会年会日本生物物理学会共催
- Invited
- Data Source
  KAKENHI-PLANNED-21H05154
[Presentation] クライオ電子顕微鏡解析から明らかになった新しいサブヌクレオソーム・H3-H4オクタソームの構造機能解析2022
- Author(s)
  野澤佳世、滝沢由政、七種和美、明石知子、胡桃坂仁志
- Organizer
  第45回日本分子生物学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] 遺伝子発現制御に関わるゲノム三次構造の構造機能解析2021
- Author(s)
  野澤佳世
- Organizer
  第94回日本生化学会大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] ゲノム三次構造が遺伝子発現に与える影響2021
- Author(s)
  野澤佳世
- Organizer
  第44回日本分子生物学会年会
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] Structural analysis of the Mediator complex in the eukaryotic transcription2021
- Author(s)
  野澤佳世
- Organizer
  日本プロテオーム学会2021大会
- Invited
- Data Source
  KAKENHI-PROJECT-20K06599
[Presentation] Structural and functional basis of the Mediator complex in the eukaryotic transcriptional system2019
- Author(s)
  Kayo Nozawa
- Organizer
  第57回日本生物物理学会年会
- Invited
- Data Source
  KAKENHI-PROJECT-19K21175
[Presentation] Crystallographic and biochemical studies of the Mediator complex provide an insight into the phosphorylation mechanism of the RNA polymerase II CTD.2019
- Author(s)
  Kayo Nozawa
- Organizer
  16th Conference of the Asian Crystallographic Association (AsCA2019)
- Invited / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K21175

1. Tsukazaki Tomoya (80436716)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 車兪徹 (40508420)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 森貴治 (90402445)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 滝沢由政

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 胡桃坂仁志

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results

Nozawa Kayo 野澤 佳世

Research Projects

Research Products

Co-Researchers

Structural and in-cell functional analysis of H3-H4 octosomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Autonomous biological systems of megadalton complexity

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural analysis of megadalton complexes in the dynamic genomePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural and functional analysis of the novel chromatin unitPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural bases of transcriptional regulation by chromatin conformationPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Cryo-EM Analysis of a Unique Subnucleosome Containing Centromere-Specific Histone Variant CENP-A.2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Asymmetric fluctuation of overlapping dinucleosome studied by cryoelectron microscopy and small-angle X-ray scattering.2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Genome-wide mapping and cryo-EM structural analyses of the overlapping tri-nucleosome composed of hexasome-hexasome-octasome moieties2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Structural basis for p53 binding to its nucleosomal target DNA sequence2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryo-electron microscopy structure of the H3-H4 octasome: A nucleosome-like particle without histones H2A and H2B2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cryo-electron microscopy structure of the H3-H4 octasome without histones H2A and H2B2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Crystallographic analysis of the overlapping dinucleosome as a novel chromatin unit2018

Author(s)

Journal Title

DOI

NAID

ISSN

Language

Data Source

[Presentation] Structural and biochemical analysis of a unique structural unit of chromatin2024

Author(s)

Organizer

Data Source

[Presentation] ユニークなゲノム基盤構造であるH3-H4オクタソームの構造機能解析2024

Author(s)

Organizer

Data Source

Nozawa Kayo 野澤佳世