WALKER DOUGLAS ウォーカーダグラス

Researcher Number	10813694
Other IDs
Affiliation (based on the past Project Information) *help	2019 – 2020: 滋賀医科大学, 神経難病研究センター, 特任教授
Review Section/Research Field	Principal Investigator Basic Section 51030:Pathophysiologic neuroscience-related
Keywords	Principal Investigator TFEB / alpha synuclein / Lewy body / autophagy / lysozome / tau / Parkinson's disease / Alzheimer's disease / polo-like kinase / transcription factor / phosphorylation

Studies on activation of TFEB to promote autophagic degradation of alpha synucleinPrincipal Investigator
- Principal Investigator
  
  WALKER DOUGLAS
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 51030:Pathophysiologic neuroscience-related
- Research Institution
  Shiga University of Medical Science

All 2020 2019

All Journal Article Presentation

[Journal Article] Effects of FTMT Expression by Retinal Pigment Epithelial Cells on Features of Angiogenesis.2020
- Author(s)
  Buyandelger Undral、Walker Douglas G.、Yanagisawa Daijiro、Morimura Toshifumi、Tooyama Ikuo
- Journal Title
  
  Int J Mol Sci.
  
  Volume: 21 Pages: 3635-3635
- DOI
  10.3390/ijms21103635
- NAID
  120006862374
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17K01355, KAKENHI-PROJECT-20K06391, KAKENHI-PROJECT-17H03560, KAKENHI-PROJECT-19K07843
[Journal Article] Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases.2020
- Author(s)
  Tsubaki H, Tooyama I, Walker DG
- Journal Title
  
  Int J Mol Sci
  
  Volume: 21 Pages: 9357-9357
- DOI
  10.3390/ijms21249357
- NAID
  120006951355
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-17H03560, KAKENHI-PROJECT-19K07843
[Journal Article] Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains2020
- Author(s)
  Walker Douglas G.、Tang Tiffany M.、Mendsaikhan Anarmaa、Tooyama Ikuo、Serrano Geidy E.、Sue Lucia I.、Beach Thomas G.、Lue Lih-Fen
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 21 Pages: 678-678
- DOI
  10.3390/ijms21020678
- Data Source
  KAKENHI-PROJECT-19K07843
[Journal Article] Novel fluorinated derivative of curcumin negatively regulates thioredoxin-interacting protein expression in retinal pigment epithelial and macrophage cells.2020
- Author(s)
  Buyandelger Undral、Walker Douglas Gordon、Taguchi Hiroyasu、Yanagisawa Daijiro、Tooyama Ikuo
- Journal Title
  
  Biochemical and Biophysical Research Communications
  
  Volume: 532 Pages: 668-674
- DOI
  10.1016/j.bbrc.2020.08.114
- NAID
  120006887065
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K12780, KAKENHI-PROJECT-17H03560, KAKENHI-PROJECT-19K07843
[Journal Article] Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin2019
- Author(s)
  Walker Douglas、Lue Lih-Fen、Beach Thomas、Tooyama Ikuo
- Journal Title
  
  Cells
  
  Volume: 8 Pages: 766-766
- DOI
  10.3390/cells8070766
- Data Source
  KAKENHI-PROJECT-19K07843
[Journal Article] Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology.2019
- Author(s)
  Mendsaikhan Anarmaa、Tooyama Ikuo、Bellier Jean-Pierre、Serrano Geidy E.、Sue Lucia I.、Lue Lih-Fen、Beach Thomas G.、Walker Douglas G.
- Journal Title
  
  Acta Neuropathol Commun
  
  Volume: 7 Pages: 215-215
- DOI
  10.1186/s40478-019-0862-8
- NAID
  120006777342
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K08853, KAKENHI-PROJECT-19K07843, KAKENHI-PROJECT-17H03560
[Presentation] mmunophenotyping of Microglia: Identification of a variant of CD105 as a marker of activated microglia in Alzheimer’s disease and Aged Brains2019
- Author(s)
  D.G. Walker, L-F. Lue, T.G. Beach, I Tooyama
- Organizer
  Alzheimer's Association International Conference 2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K07843

1. TAGUCHI Hiroyasu

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
2. 柳沢大治郎

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
3. 守村敏史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
4. 遠山育夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 4 results
5. BELLIER Jean-Pierre

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

WALKER DOUGLAS ウォーカー ダグラス

Research Projects

Research Products

Co-Researchers

Studies on activation of TFEB to promote autophagic degradation of alpha synucleinPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Effects of FTMT Expression by Retinal Pigment Epithelial Cells on Features of Angiogenesis.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Thioredoxin-Interacting Protein (TXNIP) with Focus on Brain and Neurodegenerative Diseases.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Patterns of Expression of Purinergic Receptor P2RY12, a Putative Marker for Non-Activated Microglia, in Aged and Alzheimer’s Disease Brains2020

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel fluorinated derivative of curcumin negatively regulates thioredoxin-interacting protein expression in retinal pigment epithelial and macrophage cells.2020

Author(s)

Journal Title

DOI

NAID

Data Source

[Journal Article] Microglial Phenotyping in Neurodegenerative Disease Brains: Identification of Reactive Microglia with an Antibody to Variant of CD105/Endoglin2019

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Characterization of lysosomal proteins Progranulin and Prosaposin and their interactions in Alzheimer's disease and aged brains: increased levels correlate with neuropathology.2019

Author(s)

Journal Title

DOI

NAID

Data Source

[Presentation] mmunophenotyping of Microglia: Identification of a variant of CD105 as a marker of activated microglia in Alzheimer’s disease and Aged Brains2019

Author(s)

Organizer

Data Source

WALKER DOUGLAS ウォーカーダグラス