EBIHARA TAKESHI 蛯原健

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TAKESHI EBIHARA 蛯原健

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Researcher Number	10813975
Other IDs	https://orcid.org/0000-0003-4101-0419
Affiliation (Current)	2025: 大阪大学, 医学部附属病院, 特任助教(常勤)
Affiliation (based on the past Project Information) *help	2021 – 2025: 大阪大学, 医学部附属病院, 特任助教(常勤) 2018 – 2021: 大阪大学, 医学部附属病院, 医員
Review Section/Research Field	Principal Investigator Basic Section 55060:Emergency medicine-related Except Principal Investigator Basic Section 55060:Emergency medicine-related
Keywords	Principal Investigator オートファジー / 敗血症 / サイトカイン / 脂肪 / アディポカイン / 血管内皮障害 / 熱傷 / CD63 / カドヘリン / GDF-15 … More / エクソソーム / Tカドヘリン / アディポネクチン / GDF15 / Atg5 / レジスチン / アディポサイトカイン / TRIM24 / CITED2 / 脂肪細胞 / 救急医学 / 脂肪組織 … More Except Principal Investigator 敗血症 / エピジェネテイクス / 侵襲 / トランスクリプトーム解析 / エピジェネティクス / POU2F2 / 転写因子 / ジェネティクス / 再生 / 幹細胞 / 統合解析 / 血管内皮 / ジェネテイクス / 幹細胞移植 / 多臓器障害 / 急性脳腫脹 / 外傷後早期痙攣 / 網羅的生体分子情報解析 / 網羅的蛋白発現解析 / 外傷後てんかん / RNA解析 / 網羅的ゲノム解析 / バイオマーカー / 低ナトリウム血症 / 頭部外傷 / 免疫 / 全身炎症反応 / 水素水 / 免疫担当細胞 / 水素 / 救急 / 便移植 / 炎症反応 / 集中治療 / 腸管 / メタゲノム / dysbiosis / 腸 / 全身性炎症反応 / ICU / シンバイオティクス / プロバイオティクス / IgA / FMT / 糞便微生物移植 / ＩＣＵ / 腸内細菌 Less

Molecular Pathophysiological Role of the Novel Transcription Factor POU2F2 in Sepsis
- Principal Investigator
  
  光山裕美
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  The University of Osaka
侵襲時再生治療に関する新規制御因子の解明：ゲノム・エピゲノム統合解析
- Principal Investigator
  
  小倉裕司
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
敗血症におけるエピジェネティクス制御因子のメカニズム解明
- Principal Investigator
  
  横野良典
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
脂肪細胞による全身性炎症反応制御：オートファジーとアディポカイン産生Principal Investigator
- Principal Investigator
  
  蛯原健
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築
- Principal Investigator
  
  中村洋平
- Project Period (FY)
  2022 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Elucidating the Function of Autophagy in Septic Pathology Using Adipose Tissue-Specific Atg5 Knockout MicePrincipal Investigator
- Principal Investigator
  
  Ebihara Takeshi
- Project Period (FY)
  2020 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
Analysis of immune system via gut microbiota in critically ill condition and treatment strategy for gut microbiota reconstruction.
- Principal Investigator
  
  Shimizu Kentaro
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University
The role of autophagy in biological reaction of sepsis: From the viewpoint of energy supplyPrincipal Investigator
- Principal Investigator
  
  TAKESHI EBIHARA
- Project Period (FY)
  2018 – 2019
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 55060:Emergency medicine-related
- Research Institution
  Osaka University

All 2025 2024 2022 2021 2020 2019

All Journal Article Presentation

[Journal Article] Relationship between growth differentiation factor 15 and functional prognosis and severity in traumatic brain injury2025
- Author(s)
  Ito Hiroshi、Ebihara Takeshi、Matsumoto Hisatake、Oda Jun
- Journal Title
  
  Scientific Reports
  
  Volume: 15 Issue: 1 Pages: 2470-2470
- DOI
  10.1038/s41598-025-87062-z
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-22K09140, KAKENHI-PROJECT-24K12153
[Journal Article] Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model2022
- Author(s)
  Muratsu Arisa、Ikeda Mitsunori、Shimizu Kentaro、Kameoka Shoichiro、Motooka Daisuke、Nakamura Shota、Matsumoto Hisatake、Ogura Hiroshi、Shimazu Takeshi
- Journal Title
  
  Acute Medicine & Surgery
  
  Volume: 9 Issue: 1
- DOI
  10.1002/ams2.770
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-19H03761
[Journal Article] Cytokine Elevation in Severe COVID-19 From Longitudinal Proteomics Analysis: Comparison With Sepsis2022
- Author(s)
  Ebihara T, Matsumoto H, Matsubara T, Togami Y, Nakao S, Matsuura H, Kojima T, Sugihara F, Okuzaki D, Hirata H, Yamamura H, Ogura H.
- Journal Title
  
  Frontier in immunology
  
  Volume: -
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17892
[Journal Article] Resistin Associated With Cytokines and Endothelial Cell Adhesion Molecules Is Related to Worse Outcome in COVID-192022
- Author(s)
  Ebihara Takeshi、Matsumoto Hisatake、Matsubara Tsunehiro、Togami Yuki、Nakao Shunichiro、Matsuura Hiroshi、Onishi Shinya、Kojima Takashi、Sugihara Fuminori、Okuzaki Daisuke、Hirata Haruhiko、Yamamura Hitoshi、Ogura Hiroshi
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.830061
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K17892
[Journal Article] Adipocytokine Profile Reveals Resistin Forming A Prognostic-Related Cytokine Network In The Acute Phase of Sepsis2021
- Author(s)
  Ebihara Takeshi、Matsumoto Hisatake、Matsubara Tsunehiro、Matsuura Hiroshi、Hirose Tomoya、Shimizu Kentaro、Ogura Hiroshi、Kang Sujin、Tanaka Toshio、Shimazu Takeshi
- Journal Title
  
  Shock
  
  Volume: Publish Ahead of Print Issue: 5 Pages: 718-726
- DOI
  10.1097/shk.0000000000001756
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K17892
[Journal Article] Gut Dysbiosis Associated with Antibiotics and Disease Severity and Its Relation to Mortality in Critically Ill Patients2021
- Author(s)
  Ojima Masahiro、Shimizu Kentaro、Motooka Daisuke、Ishihara Takuma、Nakamura Shota、Shintani Ayumi、Ogura Hiroshi、Iida Tetsuya、Yoshiya Kazuhisa、Shimazu Takeshi
- Journal Title
  
  Digestive Diseases and Sciences
  
  Volume: 未 Issue: 6 Pages: 2420-2432
- DOI
  10.1007/s10620-021-07000-7
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K09265, KAKENHI-PROJECT-19H03761
[Presentation] 敗血症における脂肪の役割オートファジーによる炎症の活性化2024
- Author(s)
  蛯原健
- Organizer
  第52回日本救急医学会総会
- Data Source
  KAKENHI-PROJECT-22K09140
[Presentation] 敗血症における脂肪組織でのオートファジーの役割2020
- Author(s)
  蛯原　健
- Organizer
  救急医学会
- Data Source
  KAKENHI-PROJECT-20K17892
[Presentation] LPSは脂肪組織でのオートファジーを亢進させるのか阻害するのか？2019
- Author(s)
  蛯原　健
- Organizer
  第25回日本エンドトキシン自然免疫研究会
- Data Source
  KAKENHI-PROJECT-18K16513
[Presentation] LOW DOSE LIPOPOLYSACCHARIDE(LPS) INDUCE AUTOPHAGY, BUT HIGH DOSE LPS IMPAIR AUTOPHAGY IN ADIPOSE TISSUE2019
- Author(s)
  TAKESHI EBIHARA
- Organizer
  42nd Annual CONFERENCE ON SHOCK
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K16513

1. 小倉裕司 (70301265)

# of Collaborated Projects: 5 results

# of Collaborated Products: 3 results
2. 松本寿健 (70644003)

# of Collaborated Projects: 5 results

# of Collaborated Products: 1 results
3. Shimizu Kentaro (60379203)

# of Collaborated Projects: 4 results

# of Collaborated Products: 2 results
4. 奥崎大介 (00346131)

# of Collaborated Projects: 3 results

# of Collaborated Products: 0 results
5. 松浦裕司 (10791709)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 嶋津岳士 (50196474)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
7. 新谷歩 (00724395)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福田士郎 (00896467)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 喜多俊文 (10746572)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 杉原文徳 (50381645)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
11. 中村洋平 (80644004)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
12. 伊藤弘 (80836594)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
13. 戸上由貴 (50866936)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
14. 入澤太郎 (50379202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
15. 織田順 (60459500)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
16. 光山裕美 (20787882)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
17. 横野良典 (00986911)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
18. 吉村旬平 (30835202)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
19. 西田岳史 (30986914)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
20. 小島将裕

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

EBIHARA TAKESHI 蛯原 健

TAKESHI EBIHARA 蛯原 健

Research Projects

Research Products

Co-Researchers

Molecular Pathophysiological Role of the Novel Transcription Factor POU2F2 in Sepsis

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

侵襲時再生治療に関する新規制御因子の解明：ゲノム・エピゲノム統合解析

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

敗血症におけるエピジェネティクス制御因子のメカニズム解明

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

脂肪細胞による全身性炎症反応制御：オートファジーとアディポカイン産生Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

網羅的分子生体情報を用いた頭部外傷患者に対する新たな治療戦略の構築

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidating the Function of Autophagy in Septic Pathology Using Adipose Tissue-Specific Atg5 Knockout MicePrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Analysis of immune system via gut microbiota in critically ill condition and treatment strategy for gut microbiota reconstruction.

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of autophagy in biological reaction of sepsis: From the viewpoint of energy supplyPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Relationship between growth differentiation factor 15 and functional prognosis and severity in traumatic brain injury2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Dynamic change of fecal microbiota and metabolomics in a polymicrobial murine sepsis model2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Cytokine Elevation in Severe COVID-19 From Longitudinal Proteomics Analysis: Comparison With Sepsis2022

Author(s)

Journal Title

Data Source

[Journal Article] Resistin Associated With Cytokines and Endothelial Cell Adhesion Molecules Is Related to Worse Outcome in COVID-192022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Adipocytokine Profile Reveals Resistin Forming A Prognostic-Related Cytokine Network In The Acute Phase of Sepsis2021

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Gut Dysbiosis Associated with Antibiotics and Disease Severity and Its Relation to Mortality in Critically Ill Patients2021

Author(s)

Journal Title

EBIHARA TAKESHI 蛯原健

TAKESHI EBIHARA 蛯原健

[Presentation] 敗血症における脂肪の役割オートファジーによる炎症の活性化2024