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Tarutani Airi  樽谷 愛理

ORCIDConnect your ORCID iD *help
Researcher Number 10815187
Other IDs
Affiliation (based on the past Project Information) *help 2018 – 2020: 東京大学, 大学院薬学系研究科(薬学部), 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 51030:Pathophysiologic neuroscience-related
Except Principal Investigator
Medium-sized Section 47:Pharmaceutical sciences and related fields
Keywords
Principal Investigator
プリオン様伝播 / 神経変性疾患 / αシヌクレイン / プリオン / 株(strain) / strain(株) / シヌクレイノパチー / 細胞間伝播 / シヌクレイオパチー / タウオパチー / タウ … More
Except Principal Investigator
… More 認知症 / 神経変性 / グリア細胞 / ストレス応答 Less
  • Research Projects

    (3 results)
  • Research Products

    (12 results)
  • Co-Researchers

    (8 People)
  •  異常タンパク質のプリオン様性質を決定する非タンパク質性コファクターの探索Principal Investigator

    • Principal Investigator
      樽谷 愛理
    • Project Period (FY)
      2020
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      The University of Tokyo
  •  認知症発症機構における神経変性プロセスの鍵を握る細胞病態の解明

    • Principal Investigator
      富田 泰輔
    • Project Period (FY)
      2019 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (A)
    • Review Section
      Medium-sized Section 47:Pharmaceutical sciences and related fields
    • Research Institution
      The University of Tokyo
  •  Research on prion-like propagation of distinct alpha-synuclein strains derived from human synucleinopathiesPrincipal Investigator

    • Principal Investigator
      Tarutani Airi
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 51030:Pathophysiologic neuroscience-related
    • Research Institution
      The University of Tokyo

All 2021 2020 2019 2018

All Journal Article Presentation

  • [Journal Article] Seeded assembly in vitro does not replicate the structures of α‐synuclein filaments from multiple system atrophy2021

    • Author(s)
      Lovestam Sofia、Schweighauser Manuel、Matsubara Tomoyasu、Murayama Shigeo、Tomita Taisuke、Ando Takashi、Hasegawa Kazuko、Yoshida Mari、Tarutani Airi、Hasegawa Masato、Goedert Michel、Scheres Sjors H. W.
    • Journal Title

      FEBS Open Bio

      Volume: 11 Pages: 999-1013

    • DOI

      10.1002/2211-5463.13110

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16482
  • [Journal Article] Human tauopathy-derived tau strains determine the substrates recruited for templated amplification2021

    • Author(s)
      Tarutani Airi、Miyata Haruka、Nonaka Takashi、Hasegawa Kazuko、Yoshida Mari、Saito Yuko、Murayama Shigeo、Robinson Andrew C、Mann David M A、Tomita Taisuke、Hasegawa Masato
    • Journal Title

      Brain

      Volume: -

    • DOI

      10.1093/brain/awab091

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16482
  • [Journal Article] Novel tau filament fold in corticobasal degeneration.2020

    • Author(s)
      Zhang W, Tarutani A, Newell K, Murzin A, Matsubara T, Falcon B, Vidal R, Garringer H, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW
    • Journal Title

      Nature

      Volume: 580 Pages: 283-287

    • DOI

      10.1038/s41586-020-2043-0

    • Description
      in press
    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15359, KAKENHI-PROJECT-16H06277
  • [Journal Article] Structures of α-synuclein filaments from multiple system atrophy.2020

    • Author(s)
      Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, et al
    • Journal Title

      Nature

      Volume: 585 Pages: 464-469

    • DOI

      10.1038/s41586-020-2317-6

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01015, KAKENHI-PROJECT-20K16482, KAKENHI-PROJECT-16H06277
  • [Journal Article] αシヌクレインとプリオン様伝播2019

    • Author(s)
      樽谷愛理・長谷川成人
    • Journal Title

      Clinical Neuroscience

      Volume: 37(9) Pages: 1068-1072

    • Data Source
      KAKENHI-PROJECT-18K15359
  • [Journal Article] Prion-like propagation of α-synuclein in neurodegenerative diseases.2019

    • Author(s)
      Tarutani Airi and Hasegawa Masato.
    • Journal Title

      Progress in Molecular Biology and Translational Science

      Volume: 168 Pages: 323-348

    • DOI

      10.1016/bs.pmbts.2019.07.005

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-18K15359
  • [Journal Article] Potent prion-like behaviors of pathogenic α-synuclein and evaluation of inactivation methods2018

    • Author(s)
      Tarutani A, Arai T, Murayama S, Hisanaga SI, Hasegawa M
    • Journal Title

      Acta Neuropathologica Communications

      Volume: 6 Pages: 1-18

    • DOI

      10.1186/s40478-018-0532-2

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-15H02356, KAKENHI-PROJECT-18K18443, KAKENHI-PROJECT-18K15359, KAKENHI-PLANNED-26117004, KAKENHI-PROJECT-16K07060
  • [Journal Article] N-methyl-D-aspartate receptor link to the MAP kinase pathway in cortical and hippocampal neurons and microglia is dependent on calcium sensors and is blocked by α-synuclein, Tau and phospho-Tau in non-transgenic and transgenic APPSw, Ind mice.2018

    • Author(s)
      Franco Rafael、Aguinaga David、Reyes Irene、Canela Enric I.、Lillo Jaume、Tarutani Airi、Hasegawa Masato、del Ser-Badia Anna、del Rio Jose A.、Kreutz Michael R.、Saura Carlos A.、Navarro Gemma
    • Journal Title

      Front Mol Neurosci

      Volume: 11 Pages: 273-273

    • DOI

      10.3389/fnmol.2018.00273

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15359, KAKENHI-PLANNED-26117005
  • [Presentation] Characterization of propagation patterns of distinctive alpha-synuclein strains2020

    • Author(s)
      Yanchen Liu, Yuta Ukawa, Tatsuo Mano, Masanori Kurihara, Tatsushi Toda, Atushi Iwata, Airi Tarutani, Taisuke Tomita
    • Organizer
      第39回日本認知症学会
    • Data Source
      KAKENHI-PROJECT-19H01015
  • [Presentation] Distinct prion-like seeding properties of α-synuclein strains and assessment of inactivation methods.2019

    • Author(s)
      Tarutani A, Arai T, Murayama S, Hisanaga SI, Tomita T and Hasegawa M.
    • Organizer
      WCN19 XXIV WORLD CONGRESS OF NEUROLOGY
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15359
  • [Presentation] Systematic analysis on the seeding activity of familial mutant forms of α-synuclein.2019

    • Author(s)
      Taisuke Tomita, Nung Xu, Airi Tarutani, Genta Ito
    • Organizer
      Neuroscience 2019
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19H01015
  • [Presentation] Characterization and inactivation of pathogenic α-synuclein species2018

    • Author(s)
      Airi Tarutani, Tetsuaki Arai, Shigeo Murayama, Shin-ichi Hisanaga, Taisuke Tomita, Masato Hasegawa
    • Organizer
      Neuroscience 2018
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-18K15359
  • 1.  富田 泰輔 (30292957)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 3 results
  • 2.  堀 由起子 (80610683)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 3.  高鳥 翔 (80624361)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  伊藤 弦太 (10431892)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 5.  村山 繁雄
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 6.  長谷川 成人
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 2 results
  • 7.  新井 哲明
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  久永 眞市
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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