Hirata Maki 平田真樹

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HIRATA Maki 平田真樹

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Researcher Number	10815583
Other IDs
Affiliation (Current)	2025: 徳島大学, バイオイノベーション研究所, 准教授
Affiliation (based on the past Project Information) *help	2024: 徳島大学, バイオイノベーション研究所, 准教授 2022 – 2023: 徳島大学, バイオイノベーション研究所, 講師 2020 – 2021: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 講師 2019: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 特任講師 2018: 徳島大学, 大学院社会産業理工学研究部(生物資源産業学域), 特任助教
Review Section/Research Field	Principal Investigator Basic Section 90110:Biomedical engineering-related Except Principal Investigator Basic Section 42010:Animal production science-related / Basic Section 41050:Environmental agriculture-related / Medium-sized Section 90:Biomedical engineering and related fields / Basic Section 55040:Respiratory surgery-related
Keywords	Principal Investigator マイクロミニブタ / ミニブタ / 免疫不全 / ブタ / ゲノム編集 Except Principal Investigator ブタ / ゲノム編集 / PRRS / 遺伝子改変動物 / トランスフェクション … More / 一時養鹿 / 食品安全リスク / 健康危害化学物質 / ジビエ / 野生鳥獣 / キメラ / SALL1 / TP53 / モデル動物 / 肺オルガノイド / p53遺伝子改変ブタ / 肺の修復・再生 / 急性肺障害 Less

野生鳥獣の残留危害化学物質と一時養鹿の効果検証
- Principal Investigator
  
  森松文毅
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 41050:Environmental agriculture-related
- Research Institution
  The University of Tokushima
Development of animal model for kidney-specific spontaneous tumours
- Principal Investigator
  
  音井威重
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 90:Biomedical engineering and related fields
- Research Institution
  The University of Tokushima
Production of virus infection-resistant animals by a simple genome editing procedure
- Principal Investigator
  
  音井威重
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 42010:Animal production science-related
- Research Institution
  The University of Tokushima
Production of immunodeficient micro-mini pig using genome editing technology.Principal Investigator
- Principal Investigator
  
  HIRATA Maki
- Project Period (FY)
  2018 – 2020
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 90110:Biomedical engineering-related
- Research Institution
  The University of Tokushima
The role of p53 during airway and lung injury, repair and regeneration using TP53-mutant porcine
- Principal Investigator
  
  TOBA Hiroaki
- Project Period (FY)
  2018 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 55040:Respiratory surgery-related
- Research Institution
  The University of Tokushima

All 2024 2023 2022 2021 2020 2019 2018

All Journal Article Presentation

[Journal Article] Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN2023
- Author(s)
  Tanihara Fuminori、Hirata Maki、Namula Zhao、Do Lanh Thi Kim、Yoshimura Naoaki、Lin Qingyi、Takebayashi Koki、Sakuma Tetsushi、Yamamoto Takashi、Otoi Takeshige
- Journal Title
  
  Frontiers in Cell and Developmental Biology
  
  Volume: 11 Pages: 884340-884340
- DOI
  10.3389/fcell.2023.884340
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K06137, KAKENHI-PROJECT-22K19896
[Journal Article] Comparison of chemically mediated CRISPR/Cas9 gene editing systems using different nonviral vectors in porcine embryos2023
- Author(s)
  Lin Qingyi、Takebayashi Koki、Torigoe Nanaka、Liu Bin、Namula Zhao、Hirata Maki、Tanihara Fuminori、Nagahara Megumi、Otoi Takeshige
- Journal Title
  
  Animal Science Journal
  
  Volume: 94 Issue: 1
- DOI
  10.1111/asj.13878
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] Efficiency of genetic modification in gene‐knockout sperm‐derived zygotes followed by electroporation of guide RNA targeting the same gene2023
- Author(s)
  Takebayashi Koki、Wittayarat Manita、Lin Qingyi、Torigoe Nanaka、Liu Bin、Hirata Maki、Nagahara Megumi、Tanihara Fuminori、Otoi Takeshige
- Journal Title
  
  Animal Science Journal
  
  Volume: 94 Issue: 1
- DOI
  10.1111/asj.13842
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system2023
- Author(s)
  Tanihara Fuminori、Hirata Maki、Namula Zhao、Wittayarat Manita、Do Lanh Thi Kim、Lin Qingyi、Takebayashi Koki、Hara Hiromasa、Nagahara Megumi、Otoi Takeshige
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 50 Issue: 6 Pages: 5049-5057
- DOI
  10.1007/s11033-023-08388-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study2023
- Author(s)
  Thongkittidilok Chommanart、Hirata Maki、Lin Qingyi、Torigoe Nanaka、Liu Bin、Sato Yoko、Nagahara Megumi、Tanihara Fuminori、Otoi Takeshige
- Journal Title
  
  Veterinary Medicine International
  
  Volume: 2023 Issue: 1 Pages: 1-6
- DOI
  10.1155/2023/7000858
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature2022
- Author(s)
  Lin Qingyi、Le Quynh Anh、Takebayashi Koki、Hirata Maki、Tanihara Fuminori、Thongkittidilok Chommanart、Sawamoto Osamu、Kikuchi Takeshi、Otoi Takeshige
- Journal Title
  
  Reproduction in Domestic Animals
  
  Volume: 57 Issue: 5 Pages: 556-563
- DOI
  10.1111/rda.14095
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-22K19896
[Journal Article] Short‐term preservation of porcine zygotes at ambient temperature using a chemically defined medium2022
- Author(s)
  Lin Qingyi、Le Quynh Anh、Takebayashi Koki、Hirata Maki、Tanihara Fuminori、Sawamoto Osamu、Kikuchi Takeshi、Otoi Takeshige
- Journal Title
  
  Animal Science Journal
  
  Volume: 93 Issue: 1
- DOI
  10.1111/asj.13711
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] Effects of the timing of electroporation during in vitro maturation on triple gene editing in porcine embryos using CRISPR/Cas9 system2022
- Author(s)
  Namula Zhao、Wittayarat Manita、Do Lanh Thi Kim、Van Nguyen Thanh、Lin Qingyi、Takebayashi Koki、Hirata Maki、Tanihara Fuminori、Otoi Takeshige
- Journal Title
  
  Veterinary and Animal Science
  
  Volume: 16 Pages: 100241-100241
- DOI
  10.1016/j.vas.2022.100241
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] Multiple gene editing in porcine embryos using a combination of microinjection, electroporation, and transfection methods2022
- Author(s)
  Le Quynh Anh、Wittayarat Manita、Namula Zhao、Lin Qingyi、Takebayashi Koki、Hirata Maki、Tanihara Fuminori、Do Lanh Thi Kim、Otoi Takeshige
- Journal Title
  
  Veterinary World
  
  Volume: 15 Pages: 2210-2216
- DOI
  10.14202/vetworld.2022.2210-2216
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] Gene editing in porcine embryos using a combination of electroporation and transfection methods2022
- Author(s)
  Takebayashi Koki、Wittayarat Manita、Lin Qingyi、Hirata Maki、Yoshimura Naoaki、Torigoe Nanaka、Nagahara Megumi、Do Lanh Thi Kim、Tanihara Fuminori、Otoi Takeshige
- Journal Title
  
  Reproduction in Domestic Animals
  
  Volume: 57 Issue: 10 Pages: 1136-1142
- DOI
  10.1111/rda.14184
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Journal Article] Introduction of a point mutation in the KRAS gene of in vitro fertilized porcine zygotes via electroporation of the CRISPR/Cas9 system with single-stranded oligodeoxynucleotides.2021
- Author(s)
  Wittayarat M., Hirata M., Namula Z., Sato Y., Nguyen TN., Le AQ., Lin Q., Takebayashi K., Tanihara F., Otoi T.
- Journal Title
  
  Animal Science Journal,
  
  Volume: 92 Issue: 1
- DOI
  10.1111/asj.13534
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Lipofection-Mediated Introduction of CRISPR/Cas9 System into Porcine Oocytes and Embryos2021
- Author(s)
  Hirata M., Wittayarat M., Namula Z., Le AQ., Lin Q., Takebayashi K., Thongkittidilok C., Tanihara F., Otoi T.
- Journal Title
  
  Animals
  
  Volume: 11 Issue: 2 Pages: 578-578
- DOI
  10.3390/ani11020578
- NAID
  120007147677
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Comparison of the effects of introducing the CRISPR/Cas9 system by microinjection and electroporation into porcine embryos at different stages2021
- Author(s)
  Le AQ., Tanihara F., Wittayarat M., Namula Z., Sato Y., Lin Q., Takebayashi K., Hirata M., Otoi T.
- Journal Title
  
  BMC Research Notes
  
  Volume: 14 Issue: 1 Pages: 7-7
- DOI
  10.1186/s13104-020-05412-8
- NAID
  120007147670
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] One-Step Generation of Multiple Gene-Edited Pigs by Electroporation of the CRISPR/Cas9 System into Zygotes to Reduce Xenoantigen Biosynthesis2021
- Author(s)
  Tanihara F., Hirata M., Nguyen TN., Sawamoto O., Kikuchi T., Otoi T.
- Journal Title
  
  International journal of molecular sciences
  
  Volume: 22 Issue: 5 Pages: 2249-2249
- DOI
  10.3390/ijms22052249
- NAID
  120007164926
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Evaluation of multiple gene targeting in porcine embryos by the CRISPR/Cas9 system using electroporation2020
- Author(s)
  Hirata M., Wittayarat M., Namula Z., Le AQ., Lin Q., Nguyen TN., Takebayashi K., Sato Y., Tanihara F., Otoi T.
- Journal Title
  
  Molecular Biology Reports
  
  Volume: 47 Issue: 7 Pages: 5073-5079
- DOI
  10.1007/s11033-020-05576-3
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Efficient generation of GGTA1-deficient pigs by electroporation of the CRISPR/Cas9 system into in vitro-fertilized zygotes2020
- Author(s)
  Tanihara F., Hirata M., Nguyen TN., Sawamoto O., Kikuchi T., Masako Doi., Otoi T.
- Journal Title
  
  BMC biotechnology
  
  Volume: 20 Issue: 1 Pages: 40-40
- DOI
  10.1186/s12896-020-00638-7
- NAID
  120007045051
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] One-step genome editing of porcine zygotes through the electroporation of a CRISPR/Cas9 system with two guide RNAs2020
- Author(s)
  Hirata M., Wittayarat M., Tanihara F., Sato Y., Namula Z., Le AQ., Lin Q., Takebayashi K., Otoi T.
- Journal Title
  
  In Vitro Cellular & Developmental Biology - Animal
  
  Volume: 56 Issue: 8 Pages: 614-621
- DOI
  10.1007/s11626-020-00507-9
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014
[Journal Article] Generation of CD163-edited pig via electroporation of the CRISPR/Cas9 system into porcine in vitro-fertilized zygotes2020
- Author(s)
  Tanihara, F., Hirata, M., Nguyen, TN., Le, AQ., Wittayarat, M., Fahrudin, M., Hirano, T., Otoi, T.
- Journal Title
  
  Animal Biotechnology
  
  Volume: - Issue: 2 Pages: 147-154
- DOI
  10.1080/10495398.2019.1668801
- Peer Reviewed / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-19K16014, KAKENHI-PROJECT-17H03938
[Journal Article] The relationship between embryonic development and the efficiency of target mutations in porcine endogenous retroviruses (PERVs) pol genes in porcine embryos2019
- Author(s)
  Hirata, M., Wittayarat, M., Hirano, T., Nguyen, TN., Le, AQ., Namula, Z., Fahrudin, M., Tanihara, F., Otoi, T.
- Journal Title
  
  Animals
  
  Volume: 9 Issue: 9 Pages: 593-593
- DOI
  10.3390/ani9090593
- NAID
  120006877872
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062, KAKENHI-PROJECT-17H03938
[Journal Article] Relationship among ovarian follicular status, developmental competence of oocytes, and anti-Müllerian hormone levels: A comparative study in Japanese wild boar crossbred gilts and Large White gilts.2019
- Author(s)
  Tanihara F, Hirata M, Iizuka S, Sairiki S, Nii M, Nguyen NT, Le QA, Hirano T, Otoi T.
- Journal Title
  
  Anim Sci J.
  
  Volume: 印刷中 Issue: 6 Pages: 712-718
- DOI
  10.1111/asj.13200
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-17K19325, KAKENHI-PROJECT-18K12062
[Journal Article] Effects of concentration of CRISPR/Cas9 components on genetic mosaicism in cytoplasmic microinjected porcine embryos2019
- Author(s)
  Tanihara F, Hirata M, Nguyen NT, LE QA, Hirano T, Otoi T.
- Journal Title
  
  J. Reprod. Dev.
  
  Volume: 65 Issue: 3 Pages: 209-214
- DOI
  10.1262/jrd.2018-116
- NAID
  130007662977
- ISSN
  0916-8818, 1348-4400
- Language
  English
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17H03938, KAKENHI-PROJECT-18K12062
[Presentation] Genome editing of porcine zygotes through the lipofection of a CRISPR/Cas9 system with two guide RNAs.2024
- Author(s)
  Lin Qingyi, Takebayashi Koki, Torigoe Nanaka, Liu Bin, Hirata, M., Tanihara, F., Nagahara Megumi and Otoi Takeshige.
- Organizer
  第50回国際胚移植学会
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Presentation] ブタ胚における細胞質内脂肪滴の偏在化がゲノム編集効率に及ぼす影響.2023
- Author(s)
  鳥越菜々花、Lin Qingyi、Liu, Bin、平田真樹、長原恵、音井威重
- Organizer
  第8回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-22K19896
[Presentation] Culture method and transfection reagent combinations in genome editing by lipofection in pig zygotes.2023
- Author(s)
  Lin Qingyi, Takebayashi Koki, Torigoe Nanaka, Liu Bin, Hirata Maki, Nagahara Megumi, Otoi Takeshige.
- Organizer
  第8回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-23K23764
[Presentation] Triple gene editing in porcine embryos using a combination of microinjection, electroporation, and transfection methods.2022
- Author(s)
  Lin Q, Le Q.A., Wittayarat M, Namula Z, Takebayashi K, Hirata M, Tanihara F, Do LTK, Otoi T.
- Organizer
  第7回ゲノム編集学会
- Data Source
  KAKENHI-PROJECT-23K23764
[Presentation] Comparison of chemically mediated CRISPR/Cas9 gene-editing systems using different transfection mechanisms on the mutation of porcine embryos.2022
- Author(s)
  Lin Q, Hirata M, Takebayashi K, Torigoe, N., Nagahara, M., Otoi T.
- Organizer
  The 17th Transgenic Technology Meeting
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-23K23764
[Presentation] ブタ体外受精卵におけるCRISPR/Cas9システムを用いた複数遺伝子の同時改変2019
- Author(s)
  1.平田真樹、谷原史倫、Nhien Thi Nguyen、Quynh Anh Le、平野隆之、音井威重
- Organizer
  第7回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] Effects of CRISPR/Cas9-mediated gene targeting of porcine endogenous retrovirus on the developmental competence of porcine embryos2019
- Author(s)
  Hirata, M., Tanihara, F., Nguyen, TN., Le, AQ., Hirano, T., Otoi, T.
- Organizer
  The 15th Transgenic Technology Meeting (TT2019)
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] ブタにおけるCrispr/Cas9システムを使用したゲノム編集効率化についての検討2018
- Author(s)
  平田真樹、谷原史倫、Nhien Thi Nguyen、Zhao Namula、音井威重
- Organizer
  日本ゲノム編集学会第3回大会
- Data Source
  KAKENHI-PROJECT-18K12062
[Presentation] ブタにおける成熟卵および1細胞期胚段階でのゲノム編集が胚盤胞の変異導入効率に及ぼす影響2018
- Author(s)
  平田真樹、谷原史倫、Manita Wittayarat、Nhien Thi Nguyen、 Le Anh Quynh、Zhao Namula、新居雅宏、音井威重
- Organizer
  第6回日本先進医工学ブタ研究会
- Data Source
  KAKENHI-PROJECT-18K12062

1. 音井威重 (30311814)

# of Collaborated Projects: 3 results

# of Collaborated Products: 28 results
2. 谷原史倫 (90754680)

# of Collaborated Projects: 3 results

# of Collaborated Products: 17 results
3. TOBA Hiroaki (40403745)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
4. 川上行奎 (00596249)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
5. 河北直也 (60522266)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
6. 森本雅美 (90563817)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 森松文毅 (10422510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
8. 福本晋也 (50376422)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
9. 西垣一男 (20401333)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
10. 佐久間哲史

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Hirata Maki 平田 真樹

HIRATA Maki 平田 真樹

Research Projects

Research Products

Co-Researchers

野生鳥獣の残留危害化学物質と一時養鹿の効果検証

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of animal model for kidney-specific spontaneous tumours

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production of virus infection-resistant animals by a simple genome editing procedure

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Production of immunodeficient micro-mini pig using genome editing technology.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

The role of p53 during airway and lung injury, repair and regeneration using TP53-mutant porcine

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Pigs with an INS point mutation derived from zygotes electroporated with CRISPR/Cas9 and ssODN2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Comparison of chemically mediated CRISPR/Cas9 gene editing systems using different nonviral vectors in porcine embryos2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Efficiency of genetic modification in gene‐knockout sperm‐derived zygotes followed by electroporation of guide RNA targeting the same gene2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] GHR-mutant pig derived from domestic pig and microminipig hybrid zygotes using CRISPR/Cas9 system2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Mosaic TP53 Mutation on Tumour Development in Pigs: A Case Study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Viability and developmental potential of porcine blastocysts preserved for short term in a chemically defined medium at ambient temperature2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Short‐term preservation of porcine zygotes at ambient temperature using a chemically defined medium2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Effects of the timing of electroporation during in vitro maturation on triple gene editing in porcine embryos using CRISPR/Cas9 system2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multiple gene editing in porcine embryos using a combination of microinjection, electroporation, and transfection methods2022

Author(s)

Journal Title

DOI

Data Source

Hirata Maki 平田真樹

HIRATA Maki 平田真樹

[Journal Article] Relationship among ovarian follicular status, developmental competence of oocytes, and anti-Müllerian hormone levels: A comparative study in Japanese wild boar crossbred gilts and Large White gilts.2019