Hara Makoto 原誠

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HARA Makoto 原誠

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Researcher Number	10817224
Other IDs
Affiliation (Current)	2025: 日本大学, 医学部, 准教授
Affiliation (based on the past Project Information) *help	2020 – 2024: 日本大学, 医学部, 准教授
Review Section/Research Field	Principal Investigator Basic Section 52020:Neurology-related Except Principal Investigator Basic Section 56030:Urology-related / Medium-sized Section 52:General internal medicine and related fields
Keywords	Principal Investigator 自己免疫性脳炎 / パスウェイ解析 / RNAシークエンス / 抗神経細胞表面抗体 / 単純ヘルペス脳炎 / 自己免疫 / 神経表面抗体 / 免疫沈降法 / 創薬 / マイクロアレイ … More / 抗体精製 / 免疫染色 / qPT PCR / 初代培養神経細胞 / 抗体作用 / 培養海馬神経細胞 / 神経細胞表面抗体 … More Except Principal Investigator 前立腺癌 / OCT1 / アンドロゲン受容体 / 神経細胞表面抗体群 / 神経内分泌腫瘍 / ホフマイスターイオン / シーディング / 異常型タンパク質 / 早期発見 / 血液診断 / 筋萎縮性側索硬化症 Less

Immune Responses in Neuroendocrine Prostate Cancer: Pathomechanism Insights and Applications
- Principal Investigator
  
  大日方大亮
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nihon University
molecular approach for autoimmunity triggered by herpes simplex encephalitisPrincipal Investigator
- Principal Investigator
  
  原誠
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nihon University
Epigenome-based investigation of the mechanism of therapeutic resistance in refractory prostate cancer and its application to the therapy
- Principal Investigator
  
  高橋悟
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 56030:Urology-related
- Research Institution
  Nihon University
Development of a hemodiagnosis for ALS based on the seeding reaction induced by misfolded proteins
- Principal Investigator
  
  TOKUDA Eiichi
- Project Period (FY)
  2021 – 2022
- Research Category
  
  Grant-in-Aid for Challenging Research (Exploratory)
- Review Section
  
  Medium-sized Section 52:General internal medicine and related fields
- Research Institution
  Nihon University
Molecular approaches to identify the novel therapeutic targets for the encephalitis associated with neuronal surface antibodiesPrincipal Investigator
- Principal Investigator
  
  HARA Makoto
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 52020:Neurology-related
- Research Institution
  Nihon University

All 2024 2023 2022 2021 2020

All Journal Article Presentation

[Journal Article] Brain metastasis in a patient with BRCA2-mutated treatment-related neuroendocrine prostate carcinoma and long-term response to radiotherapy and Olaparib: A case report and literature review2024
- Author(s)
  Uehara Rio、Obinata Daisuke、Hashimoto Sho、Nakahara Ken、Uchida Hideaki、Yoshizawa Tsuyoshi、Mochida Junichi、Yamaguchi Kenya、Sakaguchi Masakuni、Ozawa Yoshinari、Mori Fumi、Miura Katsuhiro、Ishige Toshiyuki、Masuda Shinobu、Nakayama Tomohiro、Takahashi Satoru
- Journal Title
  
  Medicine
  
  Volume: 103 Issue: 9 Pages: e37371-e37371
- DOI
  10.1097/md.0000000000037371
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08789
[Journal Article] Clinical characteristics of patients with metastatic castration-resistant prostate cancer after treatment with combined androgen blockade2023
- Author(s)
  Obinata Daisuke、Hashimoto Sho、Uchida Hideaki、Nakahara Ken、Yoshizawa Tsuyoshi、Mochida Junichi、Yamaguchi Kenya、Takahashi Satoru
- Journal Title
  
  BMC Urology
  
  Volume: 23 Issue: 1
- DOI
  10.1186/s12894-023-01233-6
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08789
[Journal Article] Rezum water vapor thermal therapy in patients with benign prostatic hyperplasia: Initial real-world data from Japan2023
- Author(s)
  Obinata Daisuke、Mochida Junichi、Uehara Rio、Osawa Miyu、Hashimoto Sho、Nakahara Ken、Yoshizawa Tsuyoshi、Yamaguchi Kenya、Takahashi Satoru
- Journal Title
  
  Medicine
  
  Volume: 102 Issue: 46 Pages: e36055-e36055
- DOI
  10.1097/md.0000000000036055
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08789
[Journal Article] Initial experience with prostatic urethral lift versus enucleation of the prostate: a retrospective comparative study2023
- Author(s)
  Obinata Daisuke、Uehara Rio、Hashimoto Sho、Nakahara Ken、Yoshizawa Tsuyoshi、Mochida Junichi、Yamaguchi Kenya、Takahashi Satoru
- Journal Title
  
  BMC Urology
  
  Volume: 23 Issue: 1
- DOI
  10.1186/s12894-023-01366-8
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K08789
[Journal Article] Anillin actin-binding protein expression correlates with poor prognosis for prostate cancer patients2023
- Author(s)
  Yamamoto Shinichiro、Obinata Daisuke、Takayama Kenichi、Funakoshi Daigo、Fujiwara Kyoko、Hara Makoto、Takahashi Satoru、Inoue Satoshi
- Journal Title
  
  Asian Journal of Urology
  
  Volume: in press Issue: 4 Pages: 569-574
- DOI
  10.1016/j.ajur.2023.07.002
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K06408, KAKENHI-PROJECT-23K08789
[Journal Article] Novel qEEG Biomarker to Distinguish Anti-NMDAR Encephalitis From Other Types of Autoimmune Encephalitis.2022
- Author(s)
  Mizoguchi Tomotaka, Hara Makoto, Hirose Satoshi, Nakajima Hideto
- Journal Title
  
  Frontiers in Immunology
  
  Volume: 13
- DOI
  10.3389/fimmu.2022.845272
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20K07875
[Journal Article] Practical approach for the diagnosis of disorders associated with antibodies against neuronal surface proteins2020
- Author(s)
  Hara Makoto、Nakajima Hideto、Kamei Satoshi
- Journal Title
  
  Neurology and Clinical Neuroscience
  
  Volume: 9 Issue: 1 Pages: 56-62
- DOI
  10.1111/ncn3.12462
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K07875
[Presentation] AUTOANTIBODY SCREENING USING ASSAYS WITH RAT BRAIN TISSUE AND CULTURED NEURONS FACILITATES PROMPT INDUCTION OF IMMUNOTHERAPY FOR AUTOIMMUNE ENCEPHALITIS2021
- Author(s)
  Makoto Hara、Yuki Yokota、Satoko Ninomiya、Satoshi Kamei、Hideto Nakajima
- Organizer
  第17回アジア・オセアニア神経学会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07875
[Presentation] Autoantibody screening using an in-house tissue-based assay facilitates prompt induction of immunotherapy for autoimmune encephalitis2021
- Author(s)
  Makoto Hara、Yuki Yokota、Satoko Ninomiya、Satoshi Kamei、Hideto Nakajima
- Organizer
  American Academy of Neurology Annual Meeting 2021
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07875
[Presentation] Analyses of immunolabeling patterns using a tissue-based assay can predict anti-NMDAR encephalitis2020
- Author(s)
  Hara Makoto
- Organizer
  第61回日本神経学会学術大会
- Data Source
  KAKENHI-PROJECT-20K07875

1. 大日方大亮 (20624886)

# of Collaborated Projects: 4 results

# of Collaborated Products: 4 results
2. 中嶋秀人 (20330095)

# of Collaborated Projects: 3 results

# of Collaborated Products: 4 results
3. 藤原恭子 (40595708)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
4. 井上聡 (40251251)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
5. 高橋悟 (50197141)

# of Collaborated Projects: 2 results

# of Collaborated Products: 4 results
6. TOKUDA Eiichi (00757510)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
7. 高山賢一 (50508075)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Hara Makoto 原 誠

HARA Makoto 原 誠

Research Projects

Research Products

Co-Researchers

Immune Responses in Neuroendocrine Prostate Cancer: Pathomechanism Insights and Applications

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

molecular approach for autoimmunity triggered by herpes simplex encephalitisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Epigenome-based investigation of the mechanism of therapeutic resistance in refractory prostate cancer and its application to the therapy

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of a hemodiagnosis for ALS based on the seeding reaction induced by misfolded proteins

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Molecular approaches to identify the novel therapeutic targets for the encephalitis associated with neuronal surface antibodiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Brain metastasis in a patient with BRCA2-mutated treatment-related neuroendocrine prostate carcinoma and long-term response to radiotherapy and Olaparib: A case report and literature review2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Clinical characteristics of patients with metastatic castration-resistant prostate cancer after treatment with combined androgen blockade2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rezum water vapor thermal therapy in patients with benign prostatic hyperplasia: Initial real-world data from Japan2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Initial experience with prostatic urethral lift versus enucleation of the prostate: a retrospective comparative study2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Anillin actin-binding protein expression correlates with poor prognosis for prostate cancer patients2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Novel qEEG Biomarker to Distinguish Anti-NMDAR Encephalitis From Other Types of Autoimmune Encephalitis.2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Practical approach for the diagnosis of disorders associated with antibodies against neuronal surface proteins2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] AUTOANTIBODY SCREENING USING ASSAYS WITH RAT BRAIN TISSUE AND CULTURED NEURONS FACILITATES PROMPT INDUCTION OF IMMUNOTHERAPY FOR AUTOIMMUNE ENCEPHALITIS2021

Author(s)

Organizer

Data Source

[Presentation] Autoantibody screening using an in-house tissue-based assay facilitates prompt induction of immunotherapy for autoimmune encephalitis2021

Author(s)

Organizer

Data Source

[Presentation] Analyses of immunolabeling patterns using a tissue-based assay can predict anti-NMDAR encephalitis2020

Author(s)

Hara Makoto 原誠

HARA Makoto 原誠