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Hara Yasumasa  原 康雅

… Alternative Names

Yasumasa Hara  原 康雅

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Researcher Number 10824625
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0451-8731
Affiliation (Current) 2025: 香川大学, 農学部, 助教
Affiliation (based on the past Project Information) *help 2023: 香川大学, 農学部, 助教
2019 – 2022: 千葉大学, 大学院薬学研究院, 助教
2018: 千葉大学, 大学院薬学研究院, 特任助教
Review Section/Research Field
Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related / 0801:Pharmaceutical sciences and related fields
Except Principal Investigator
Basic Section 47050:Environmental and natural pharmaceutical resources-related / Natural medicines
Keywords
Principal Investigator
微生物資源 / 共培養 / 放線菌Nocardia属 / 培養抽出物ライブラリー / 放線菌 / 培養抽出物ライブラリー構築 / 天然物 / 共培養抽出物ライブラリー構築 / 放線菌Nocardia / 土壌由来放線菌 / 培養抽出ライブラリー構築 / ミコール酸含有細菌 / 海洋由来真菌 … More
Except Principal Investigator
… More 薬学 / 有機化学 / 生体分子 / シグナル伝達 / 生理活性 Less
  • Research Projects

    (5 results)
  • Research Products

    (81 results)
  • Co-Researchers

    (9 People)
  •  環境模倣型微生物培養法を用いた新規天然物探索とその機能解明Principal Investigator

    • Principal Investigator
      原 康雅
    • Project Period (FY)
      2023 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Kagawa University
  •  Search for new drug seeds by co-culture method that mimics the growth environment of microorganismsPrincipal Investigator

    • Principal Investigator
      Hara Yasumasa
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Chiba University
  •  Search for bioactive natural products with overcoming effects on cancer-heterogeneity

    • Principal Investigator
      Masami Ishibashi
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Chiba University
  •  Advancement of resources for drug discovery seeds utilizing microbial interactions and elucidation of activation mechanism of microbial dormant gene clustersPrincipal Investigator

    • Principal Investigator
      Yasumasa Hara
    • Project Period (FY)
      2018 – 2019
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Chiba University
  •  Search and function elucidation of highly active natural products targeting cancer microenvironmental signals

    • Principal Investigator
      Ishibashi Masami
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Natural medicines
    • Research Institution
      Chiba University

All 2024 2023 2022 2021 2020 2019 2018 2016

All Journal Article Presentation

  • [Journal Article] Isolation of bioactive phytochemicals from Crinum asiaticum L. along with their cytotoxic and TRAIL-resistance abrogating prospect assessment2024

    • Author(s)
      Rakhi Sharmin Ahmed、Hara Yasumasa、Islam Md. Saiful、Manome Teruhisa、Alam Safaet、Emon Nazim Uddin、Al-Mansur Muhammad Abdullah、Kuddus Md. Ruhul、Sarkar Md. Raihan、Ishibashi Masami、Ahmed Firoj
    • Journal Title

      Heliyon

      Volume: 10 Issue: 3 Pages: e25049-e25049

    • DOI

      10.1016/j.heliyon.2024.e25049

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Journal Article] A new 1,2-diketone physalin isolated from Physalis minima and TRAIL-resistance overcoming activity of physalins2023

    • Author(s)
      Teruhisa Manome, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      Journal of Natural Medicines

      Volume: 77 Issue: 2 Pages: 370-378

    • DOI

      10.1007/s11418-022-01670-x

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Journal Article] Isolation of two new trichorzin PA derivatives, trichorzin PA X and XI, from the terrestrial fungus Trichoderma harzianum IFM 667362023

    • Author(s)
      Hara Yasumasa、Manome Teruhisa、Suehiro Wataru、Harada Shinji、Yamagishi Yoshikazu、Takaya Akiko、Ogra Yasumitsu、Ishibashi Masami
    • Journal Title

      Tetrahedron Letters

      Volume: 121 Pages: 154488-154488

    • DOI

      10.1016/j.tetlet.2023.154488

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-22K06496, KAKENHI-PROJECT-23K14369
  • [Journal Article] Resveratrol tetramer vaticanol N with a tribenzobicyclo[3.3.2]decatriene skeleton isolated from the leaves of Vatica bantamensis2023

    • Author(s)
      Ito Tetsuro、Hara Yasumasa、Fukaya Masashi、Ryu Kaori、Iinuma Munekazu
    • Journal Title

      Phytochemistry Letters

      Volume: 57 Pages: 16-21

    • DOI

      10.1016/j.phytol.2023.06.007

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Journal Article] Two bioactive compounds, uniformides A and B, isolated from a culture of Nocardia uniformis IFM0856T in the presence of animal cells2022

    • Author(s)
      Hara, Y.; Watanabe, K.; Takaya, A.; Ebihara, I.; Manome, T.; Arai, M. A.; Yaguchi, T.; Ishibashi, M.
    • Journal Title

      Org. Lett.

      Volume: 24 Issue: 27 Pages: 4998-5002

    • DOI

      10.1021/acs.orglett.2c02092

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-21H02639, KAKENHI-PROJECT-20K16024
  • [Journal Article] Two bioactive compounds, uniformides A and B, isolated from a culture of Nocardia uniformis IFM0856T in the presence of animal cells2022

    • Author(s)
      Yasumasa Hara, Keiichiro Watanabe, Akiko Takaya, Itsuki Ebihara, Teruhisa Manome, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Organic Letters

      Volume: 24 Pages: 4998-5002

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Journal Article] New polyoxygenated cyclohexenes isolated from Uvaria rufa and cinnamtannin B1 isolated from Nephelium hypoleucum with TRAIL-resistance-overcoming activity2022

    • Author(s)
      Jitrangsri Kritamorn、Hara Yasumasa、Takaya Akiko、Ishibashi Masami
    • Journal Title

      Phytochemistry Letters

      Volume: 52 Pages: 7-9

    • DOI

      10.1016/j.phytol.2022.08.010

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-20K16024
  • [Journal Article] Corrrection to “Two Bioactive Compounds, Uniformides A and B, Isolated from a Culture of Nocardia uniformis IFM0856T in the Presence of Animal Cells”2022

    • Author(s)
      Yasumasa Hara, Keiichiro Watanabe, Akiko Takaya, Itsuki Ebihara, Teruhisa Manome, Midori A.Arai, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Organic Letters

      Volume: 24 Issue: 31 Pages: 5867-5867

    • DOI

      10.1021/acs.orglett.2c02441

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Journal Article] Natural Compounds with BMI1 Promoter Inhibitory Activity from <i>Mammea siamensis</i> and <i>Andrographis paniculata</i>2022

    • Author(s)
      Fujii Kazuki、Hara Yasumasa、Arai Midori A.、Sadhu Samir K.、Ahmed Firoj、Ishibashi Masami
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 70 Issue: 12 Pages: 885-891

    • DOI

      10.1248/cpb.c22-00556

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2022-12-01
    • Language
      English
    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-20K16024
  • [Journal Article] Thannilignan glucoside and 2-(β-glucopyranosyl)-3-isoxazolin-5-one derivative, two new compounds isolated from Terminalia bellirica2022

    • Author(s)
      Manome Teruhisa、Hara Yasumasa、Ahmed Firoj、Sadhu Samir K.、Ishibashi Masami
    • Journal Title

      Journal of Natural Medicines

      Volume: 76 Issue: 2 Pages: 482-489

    • DOI

      10.1007/s11418-021-01593-z

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Journal Article] Isolation of Ikahonone, 4-Methyl-2,4-dihydroxy-3-pentanone from Bacillus cereus IFM122352022

    • Author(s)
      Ishibashi Masami、Hara Yasumasa、Chiba Mareno、Watanabe Keiichiro
    • Journal Title

      HETEROCYCLES

      Volume: 105 Issue: 1 Pages: 523-523

    • DOI

      10.3987/com-21-s(r)4

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-20K16024
  • [Journal Article] Isolation of peptidolipin NA derivatives from the culture of Nocardia arthritidis IFM10035T in the presence of mouse macrophage cells2022

    • Author(s)
      Yasumasa Hara, Daiki Tanimura, Teruhisa Manome, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Heterocycles

      Volume: 104 Issue: 1 Pages: 185-190

    • DOI

      10.3987/com-21-14567

    • NAID

      40022782818

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-20K16024
  • [Journal Article] Isolation of various flavonoids with TRAIL resistance-overcoming activity from Blumea lacera2022

    • Author(s)
      Manome Teruhisa、Hara Yasumasa、Ishibashi Masami
    • Journal Title

      Molecules

      Volume: 28 Issue: 1 Pages: 264-264

    • DOI

      10.3390/molecules28010264

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-20K16024
  • [Journal Article] Acacienone, a terpenoid-like natural product having an unprecedented C20 framework isolated from Acacia mangium leaves2021

    • Author(s)
      Yasumasa Hara, Yuichi Totsugi, Hiroshi Ichikawa, Shinji Harada, Kazuki Fujii, Firoj Ahmed, Samir K. Sadhu, Midori A. Arai, Masami Ishibashi
    • Journal Title

      Journal of Natural Medicines

      Volume: 75 Issue: 1 Pages: 99-104

    • DOI

      10.1007/s11418-020-01457-y

    • NAID

      40022463001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-18H02582, KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-21H02639
  • [Journal Article] Bioactivity-guided isolation of TRAIL-resistance overcoming activity compounds from the leaves of Murraya exotica2021

    • Author(s)
      Kritamorn Jitrangsri, Akiko Takaya, Yasumasa Hara, Samir K. Sadhu, Firoj Ahmed, Masami Ishibashi
    • Journal Title

      Natural Product Communications

      Volume: 16 Issue: 12 Pages: 1-6

    • DOI

      10.1177/1934578x211065843

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Journal Article] Isolation of adenosine and cordysinin B from Anredera cordifolia that stimulates CRE-mediated transcription in PC12 cells2021

    • Author(s)
      Yasushi Ohizumi, Michi Kawada, Maki Kamada, Akira Nakajima, Koji Kajima, Nobuyuki Uozumi, Yasumasa Hara, Yuanqiang Guo, Masami Ishibashi
    • Journal Title

      Planta Medica International Open

      Volume: 8 Issue: 01 Pages: e19-e24

    • DOI

      10.1055/a-1395-6510

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Journal Article] Evaluation of naturally occurring HIF-1 inhibitors for pulmonary arterial hypertension2021

    • Author(s)
      Midori A. Arai, Kota Sakuraba, Yoshinori Makita, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      ChemBioChem

      Volume: 22 Issue: 18 Pages: 2799-2804

    • DOI

      10.1002/cbic.202100223

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-20H03394, KAKENHI-PROJECT-21H02639
  • [Journal Article] Cadinane sesquiterpenoids isolated from Santalum album using a screening program for Wnt signal inhibitory activity2020

    • Author(s)
      Tomoyuki Sato, Midori A. Arai, Yixizhuoma, Yasumasa Hara, Takashi Koyano, Thaworn Kowithayakorn, Masami Ishibashi
    • Journal Title

      Journal of Natural Medicines

      Volume: 74 Issue: 2 Pages: 476-481

    • DOI

      10.1007/s11418-019-01380-x

    • NAID

      40022183696

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03992, KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-20H03394
  • [Journal Article] Nonactic acid derivatives isolated from Streptomyces werraensis IFM12104 in a screening program for BMI1 promoter inhibitory activity2019

    • Author(s)
      Yusuke Yokoyama, Midori A. Arai, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      Natural Products Communications

      Volume: 14 Issue: 7 Pages: 1-5

    • DOI

      10.1177/1934578x19866583

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-17H03992
  • [Journal Article] Mycobacterium smegmatis alters the production of secondary metabolites by marine-derived Aspergillus niger2019

    • Author(s)
      Jomori Takahiro、Hara Yasumasa、Sasaoka Miho、Harada Kazuo、Setiawan Andi、Hirata Kazumasa、Kimishima Atsushi、Arai Masayoshi
    • Journal Title

      Journal of Natural Medicines

      Volume: 74 Issue: 1 Pages: 76-82

    • DOI

      10.1007/s11418-019-01345-0

    • NAID

      40022130030

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H04645, KAKENHI-PROJECT-19K21222
  • [Journal Article] Identification of BMI1 promoter inhibitors from Streptomyces sp. IFM-119582019

    • Author(s)
      Yusuke Yokoyama, Midori A. Arai, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      Bioorganic and Medicinal Chemistry

      Volume: 27 Issue: 13 Pages: 2998-3003

    • DOI

      10.1016/j.bmc.2019.05.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-17H03992, KAKENHI-PROJECT-18H02582
  • [Journal Article] Sucupiranins M-Q, five new furanocassane-type diterpenoids from the seeds of Bowdichia virgilioides2019

    • Author(s)
      Endo Yuta, Kasahara Taku, Asakura Kenta, Mori Ayana, Funasaki Mariko, Akisue Gokithi, Etoh Tadahiro, Harada Kenichi, Fukuyama Yoshiyasu, Matsuzaki Keiichi, Ishibashi Masami, Ohsaki Ayumi
    • Journal Title

      Tetrahedron

      Volume: 75 Issue: 37 Pages: 130511-130511

    • DOI

      10.1016/j.tet.2019.130511

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K01921, KAKENHI-PROJECT-19K05488, KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-17H03992
  • [Journal Article] Isolation of Nabscessin C from <i>Nocardia abscessus</i> IFM 10029<sup>T</sup> and a Study on Biosynthetic Pathway for Nabscessins2018

    • Author(s)
      Shoko Hara, Yasumasa Hara, Midori A. Arai, Yoko Kusuya, Hiroki Takahashi, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Chemical and Pharmaceutical Bulletin

      Volume: 66 Issue: 10 Pages: 976-982

    • DOI

      10.1248/cpb.c18-00430

    • NAID

      130007492854

    • ISSN
      0009-2363, 1347-5223
    • Year and Date
      2018-10-01
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Journal Article] Coculture of a pathogenic actinomycete and animal cells to produce nocarjamide, a cyclic nonapeptide with Wnt signal-activating effect2018

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Kazufumi Toume, Hyuma Masu, Tomoyuki Sato, Katsuko Komatsu, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Organic Letters

      Volume: 20 Pages: 5831-5834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Journal Article] Nabscessins A and B, new aminocyclitol derivatives from Nocardia abscessus IFM 10029T2016

    • Author(s)
      Shoko Hara, Naoki Ishikawa, Yasumasa Hara, Tatsuo Nehira, Kanae Sakai, Tohru Gonoi, Masami Ishibashi
    • Journal Title

      Journal of Natural Products

      Volume: 80 Issue: 2 Pages: 565-568

    • DOI

      10.1021/acs.jnatprod.6b00935

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K05696, KAKENHI-PROJECT-16K14910, KAKENHI-PROJECT-17H03992
  • [Presentation] Analysis of ClpP activation and antibacterial activity of Koetjapic acid derived from Sandricum indicum2024

    • Author(s)
      Takumi Segawa, Keisuke Sugimoto, Junpei Yamaguchi, Yasumasa Hara, Takahito Kuribara, Tetsuro Nemoto, Akiko Takaya
    • Organizer
      10th Global Network Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 動物細胞存在下Nocardia pseudobrasiliensis IFM 0624T等の培養による新規天然物の探索2024

    • Author(s)
      瀬戸 陽介, 原 康雅, 高屋 明子, 海老原 樹, 荒井 緑, 矢口 貴志, 石橋 正己
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] ハマゴウに含まれるジテルペン類の単離,構造決定ならびに生物活性評価2024

    • Author(s)
      花木祐輔,安部凛太郎,岩瀬二千翔,杉山康憲,原康雅,柳田亮
    • Organizer
      日本農芸化学会2024年度大会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 熱帯植物Xylia kerriiからの関節リウマチ滑膜線維芽細胞の細胞死誘導作用を有する新規天然物の探索2024

    • Author(s)
      原 康雅, 藤井 一樹, 高屋 明子, 石橋 正己
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 細菌に対するSandricum indicum由来Koetjapic acidの薬理作用2024

    • Author(s)
      瀬川 卓弥, 杉本 佳祐, 山口 隼平, 原 康雅, 栗原 崇人, 根本 哲宏, 高屋 明子
    • Organizer
      日本薬学会第144年会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] Anti-staphylococcus aureus compound was found in genus Nocardia2024

    • Author(s)
      Yu Lu, Yosuke Seto, Yasumasa Hara, Akiko Takaya, Hiroki Takahashi
    • Organizer
      10th Global Network Forum on Infection and Immunity
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 休眠遺伝子活性化を目指した病原真菌と免疫細胞の共培養2024

    • Author(s)
      氏江 優希子, 齋藤 駿, 桑原 るり, 原 康雅, 深谷 圭介, 占部 大介, 矢口 貴志, 石橋 正己, 荒井 緑
    • Organizer
      日本農芸化学会2024年度大会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] フェノキサジン環を持たない新規Actinomycin誘導体の合成及び生物活性評価2024

    • Author(s)
      山上 健太, 花木 祐輔, 原 康雅, 柳田 亮
    • Organizer
      日本農芸化学会2024年度大会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 放線菌Nocardia carnea IFM 12324からの新規天然物の探索と生合成遺伝子解析2023

    • Author(s)
      馬目 照久, 中村 文香, 原 康雅, 高屋 明子, 伴 さやか, 高橋 弘喜, 矢口 貴志, 石橋 正己
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 同一土壌分離放線菌の共培養等からの抗真菌活性を指標とした天然物の探索2023

    • Author(s)
      浅沼 朋花, 原 康雅, 千葉 まれの, 高屋 明子, 石橋 正己
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 熱帯植物Xylia kerri等からの関節リウマチ滑膜線維芽細胞の細胞死誘導作用を有する天然物探索2023

    • Author(s)
      原 康雅, 岩田 樹, 藤井 一樹, 松岡 優輝, 高屋 明子, 石橋 正己
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Co-culture of pathogenic fungi and immune cells for activating silent genes2023

    • Author(s)
      Yukiko Ujiie, Shun Saito, Ruri Kuwahara, Yasumasa Hara, Keisuke Fukaya, Daisuke Urabe, Takashi Yaguchi, Masami Ishibashi, Midori A. Arai
    • Organizer
      13th International Symposium on Bioorganic Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] Search for natural products from actinomycetes with anti-fungal activity2023

    • Author(s)
      Tomoka Asanuma, Yasumasa Hara, Mareno Chiba, Akiko Takaya, Masami Ishibashi
    • Organizer
      The 3rd CRI-CGI-Chiba Symposium in Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Nocardia属放線菌からの抗炎症天然物の探索2023

    • Author(s)
      三宅 真未, 原 康雅, 渡邊 圭一郎, 高屋 明子, 矢口 貴志, 石橋 正己
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] フタバガキ科Vatica bantamensis 由来レスベラトロール六量体の構造決定2023

    • Author(s)
      伊藤 哲朗, 原 康雅, 澤 竜一, 久保田 由美子, 林 京子, 河原 敏男, 飯沼 宗和
    • Organizer
      第65回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] Molecular mechanism of Physalin H to suppress the Agr-quorum sensing system of methicillin-resistant Staphylococcus aureus2023

    • Author(s)
      Junpei Yamaguchi, Teruhisa Manome, Yasumasa Hara, Yuriko Yamazaki, Yuumi Matsuoka, Masami Ishibashi, Akiko Takaya
    • Organizer
      The 3rd CRI-CGI-Chiba Symposium in Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 病原性放線菌Nocardiaからの新規天然物の探索2023

    • Author(s)
      原康雅
    • Organizer
      日本生薬学会第69回年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] 熱帯植物や病原性放線菌等からの新規天然物の探索2023

    • Author(s)
      原康雅
    • Organizer
      第24回天然薬物の開発と応用シンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] Search for new natural products from actinomycetes of the genus Nocardia in the presence of animal cells2023

    • Author(s)
      Yasumasa Hara
    • Organizer
      The 3rd CRI-CGI-Chiba Symposium in Chemistry
    • Invited / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for natural products with BMI1 promoter inhibitory effect from Andrographis paniculata and Mammea siamensis2023

    • Author(s)
      Kazuki Fujii, Yasumasa Hara, Masami Ishibashi
    • Organizer
      The 3rd CRI-CGI-Chiba Symposium in Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 非カルバペネマーゼ産生クレブシエラにおけるメロペネム寛容性機構2023

    • Author(s)
      山中 夏樹, 山口 隼平, 高橋 弘喜, 原 康雅, 石橋 正己, 高屋 明子
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Physalin Hによる黄色ブドウ球菌agrクオラムセンシングシステム抑制機構2023

    • Author(s)
      山口 隼平, 馬目 照久, 原 康雅, 山崎 由里子, 松岡 悠美, 石橋 正己, 高屋 明子
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Caesalpinia digyna からの BMI1プロモーター阻害作用を示す天然物の探索2023

    • Author(s)
      藤井 一樹, 原 康雅, 高屋 明子, Firoj Ahmed, Samir K. Sadhu, 石橋 正己
    • Organizer
      日本薬学会第143年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 休眠遺伝子活性化を目指した病原真菌Aspergillus 属と免疫細胞の共培養2023

    • Author(s)
      氏江 優希子, 齋藤 駿, 桑原 るり, 原 康雅, 深谷 圭介, 占部 大介, 岸本 真治, 渡辺 賢二, 後藤 芳邦, 小川 健司, 楠屋 陽子, 高橋 弘喜, 矢口 貴志, 石橋 正己, 荒井 緑
    • Organizer
      第65回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-23K14369
  • [Presentation] BMI1プロモーター阻害作用をもつ植物成分の探索研究2022

    • Author(s)
      藤井 一樹,原 康雅,Firoj Amed, Samir K. Sadhu, 石橋 正己
    • Organizer
      第64回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 動物細胞存在下Nocardia uniformisの培養を用いた生物活性天然物の探索2022

    • Author(s)
      原 康雅,渡邊 圭一郎,高屋 明子,海老原 樹, 馬目 照久,荒井 緑, 矢口 貴志,石橋 正己
    • Organizer
      日本生薬学会第68回年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] BMI1プロモーター阻害作用をもつ植物成分の探索研究2022

    • Author(s)
      藤井一樹,原康雅,石橋正己
    • Organizer
      第64回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 動物細胞存在下Nocardia uniformisの培養を用いた生物活性天然物の探索2022

    • Author(s)
      原康雅,渡邊圭一郎,高屋明子,馬目照久,矢口貴志,石橋正己
    • Organizer
      日本生薬学会第68年会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 真菌Trichoderma harzianum IFM 66736等からのがん細胞死を誘導する天然物の探索2022

    • Author(s)
      馬目 照久,末広 航,原 康雅,原田 真至,石橋 正己
    • Organizer
      第9回食品薬学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 真菌Trichoderma harzianum IFM66736等からのがん細胞死を誘導する天然物の探索2022

    • Author(s)
      馬目照久,末広航,原田真至,原康雅,石橋正己
    • Organizer
      第9回食品薬学シンポジウム
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Physalis minimaからの新規 physalin 探索とその TRAIL 耐性克服作用の作用機序解析2022

    • Author(s)
      馬目 照久,原 康雅,石橋 正己
    • Organizer
      日本生薬学会第68回年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Physalis minimaからの新規 physalin 探索とその TRAIL 耐性克服作用の作用機序解析2022

    • Author(s)
      馬目照久,原康雅,石橋正己
    • Organizer
      日本生薬学会第68年会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 動物細胞との共培養法による病原性放線菌Nocardia属からの新規天然物の探索2021

    • Author(s)
      原 康雅,矢口 貴志,石橋 正己
    • Organizer
      第63回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for natural products from Terminalia bellirica with AGS cytotoxicity2021

    • Author(s)
      Teruhisa Manome, Yasumasa Hara, Firoj Ahmed, Samir K. Sadhu, Masami Ishibashi
    • Organizer
      The 11th JSP-CSP-KSP Joint Symposium on Pharmacognosy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 真菌Clonostachys rogersoniana IFM66735 からの大腸がん細胞死を誘導する天然物の探索2021

    • Author(s)
      末広航,原康雅,石橋正己
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Search for natural products from Terminalia bellirica and Blumea lacera2021

    • Author(s)
      Teruhisa Manome, Yasumasa Hara, Firoj Ahmed, Samir K. Sadhu, Masami Ishibashi
    • Organizer
      The 2nd CRI-CGI-Chiba Symposium in Chemistry
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 病原性放線菌Nocardia属からの新規天然物の探索2021

    • Author(s)
      原康雅
    • Organizer
      日本生薬学会第67年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 動物細胞との共培養法による病原性放線菌Nocardia属からの新規天然物の探索2021

    • Author(s)
      原康雅,矢口貴志,石橋正己
    • Organizer
      第63回天然有機化合物討論会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 病原性放線菌Nocardia arthritidis等と動物細胞との共培養法を用いた天然物の探索2021

    • Author(s)
      原 康雅, 谷村 大樹, 荒井 緑, 矢口 貴志, 石橋 正己
    • Organizer
      第23回天然薬物の開発と応用シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2021

    • Author(s)
      Yasumasa Hara, Midori Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      Pacifichem 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 抗菌活性を指標とした微生物由来生物活性天然物の探索2021

    • Author(s)
      原 康雅,千葉 まれの,石橋 正己
    • Organizer
      第65回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 動物細胞との共培養法による病原性放線菌Nocardia属由来新規生物活性天然物の探索 (2)2021

    • Author(s)
      原 康雅,矢口 貴志,石橋 正己
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for natural products with BMI1 promoter inhibitory effect from Andrographis paniculata2021

    • Author(s)
      Kazuki Fujii, Yasumasa Hara, Midori A. Arai, Samir K. Sadhu, Firoj Ahmed, Masami Ishibashi
    • Organizer
      Pacifichem 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Bioactive compounds with TRAIL-resistance overcoming activity from Murraya exotica2021

    • Author(s)
      Kritamorn Jitrangsri, Yasumasa Hara, Akiko Takaya, and Masami Ishibashi
    • Organizer
      The 11th JSP-CSP-KSP Joint Symposium on Pharmacognosy
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 病原性放線菌Nocardia属からの新規天然物の探索2021

    • Author(s)
      原 康雅
    • Organizer
      日本生薬学会第67年会
    • Invited
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2021

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      Pacifichem 2021
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 病原真菌Aspergillus fumigatusと免疫細胞の共培養法を用いた新規天然物の探索2021

    • Author(s)
      桑原 るり, 原 康雅, 荒井 緑, 矢口 貴志, 石橋 正己
    • Organizer
      第23回天然薬物の開発と応用シンポジウム
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2020

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      2nd German-Japanese Symposium on Natural Product Biosynthesis
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Andrographis paniculataからの BMI1 プロモーター阻害作用を示す天然物の探索2020

    • Author(s)
      藤井一樹,荒井緑,原康雅,S. K. Sadhu,F. Ahmed,石橋正己
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 微生物の生育環境を模倣した共培養法による新規天然物の探索2020

    • Author(s)
      千葉 まれの, 原 康雅, 石橋 正己
    • Organizer
      日本薬学会140年会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2020

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      2nd German-Japanese Joint Symposium on the Biosynthesis of Natural Products
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 関節リウマチ由来滑膜細胞に選択的にアポトーシス経路を誘導する天然物の探索2020

    • Author(s)
      山崎秀太,原康雅,小谷野喬,T. Kowithayakorn,石橋正己
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Santalum album からのWnt シグナル阻害作用をもつ天然物の探索2019

    • Author(s)
      佐藤知幸,荒井緑,原康雅,益西卓瑪,小谷野喬,Thaworn Kowithayakorn,石橋正己
    • Organizer
      日本生薬学会第66回年会
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Presentation] 放線菌からのBMI1 プロモーター阻害作用をもつ天然物の探索2019

    • Author(s)
      横山夕将, 荒井緑, 原康雅, 石橋正己
    • Organizer
      第8回食品薬学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Presentation] 微生物共培養法を利用した活性天然物の探索2018

    • Author(s)
      城森 啓宏, 原 康雅, 笹岡 美歩, Andi Setiawan, 荒井 雅吉
    • Organizer
      第68回日本薬学会近畿支部総会・大会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • [Presentation] 微生物共培養法を利用した活性天然物の探索2018

    • Author(s)
      城森 啓宏, 笹岡 美歩,原 康雅,Andi Setiawan,荒井 雅吉
    • Organizer
      日本生薬学会第65回年会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • 1.  Ishibashi Masami (90212927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 30 results
  • 2.  荒井 緑 (40373261)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 3.  石川 直樹 (20748826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 4.  高屋 明子 (80334217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 5 results
  • 5.  HARADA Shinji
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 6.  荒井 雅吉
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 7.  大崎 愛弓
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 8.  福山 愛保
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results
  • 9.  根平 達夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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