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Hara Yasumasa  原 康雅

… Alternative Names

Yasumasa Hara  原 康雅

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Researcher Number 10824625
Other IDs
  • ORCIDhttps://orcid.org/0000-0003-0451-8731
Affiliation (Current) 2022: 千葉大学, 大学院薬学研究院, 助教
Affiliation (based on the past Project Information) *help 2019 – 2022: 千葉大学, 大学院薬学研究院, 助教
2018: 千葉大学, 大学院薬学研究院, 特任助教
Review Section/Research Field
Principal Investigator
0801:Pharmaceutical sciences and related fields / Basic Section 47050:Environmental and natural pharmaceutical resources-related
Except Principal Investigator
Natural medicines / Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords
Principal Investigator
共培養 / 微生物資源 / 放線菌 / 培養抽出物ライブラリー / 培養抽出物ライブラリー構築 / 海洋由来真菌 / ミコール酸含有細菌 / 培養抽出ライブラリー構築 / 土壌由来放線菌 / 放線菌Nocardia属 / 共培養抽出物ライブラリー構築 … More
Except Principal Investigator
… More 生理活性 / シグナル伝達 / 生体分子 / 有機化学 / 薬学 Less
  • Research Projects

    (4 results)
  • Research Products

    (17 results)
  • Co-Researchers

    (5 People)
  •  Search for bioactive natural products with overcoming effects on cancer-heterogeneity

    • Principal Investigator
      石橋 正己
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Chiba University
  •  微生物の生育環境を模倣した共培養法による新規医薬シーズ探索とその産生機構解明Principal Investigator

    • Principal Investigator
      原 康雅
    • Project Period (FY)
      2020 – 2022
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47050:Environmental and natural pharmaceutical resources-related
    • Research Institution
      Chiba University
  •  Advancement of resources for drug discovery seeds utilizing microbial interactions and elucidation of activation mechanism of microbial dormant gene clustersPrincipal Investigator

    • Principal Investigator
      Yasumasa Hara
    • Project Period (FY)
      2019
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0801:Pharmaceutical sciences and related fields
    • Research Institution
      Chiba University
  •  Search and function elucidation of highly active natural products targeting cancer microenvironmental signals

    • Principal Investigator
      Ishibashi Masami
    • Project Period (FY)
      2017 – 2019
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Research Field
      Natural medicines
    • Research Institution
      Chiba University

All 2021 2020 2019 2018 2017

All Journal Article Presentation

  • [Journal Article] Acacienone, a terpenoid-like natural product having an unprecedented C20 framework isolated from Acacia mangium leaves2021

    • Author(s)
      Yasumasa Hara, Yuichi Totsugi, Hiroshi Ichikawa, Shinji Harada, Kazuki Fujii, Firoj Ahmed, Samir K. Sadhu, Midori A. Arai, Masami Ishibashi
    • Journal Title

      Journal of Natural Medicines

      Volume: 75 Pages: 99-104

    • DOI

      10.1007/s11418-020-01457-y

    • NAID

      40022463001

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-18H02582, KAKENHI-PROJECT-20H03394
  • [Journal Article] Dehydropropylpantothenamide isolated by a co-culture of Nocardia tenerifensis IFM 10554T in the presence of animal cells2020

    • Author(s)
      Tomoyuki Sato, Midori A. Arai, Yixizhuoma, Yasumasa Hara, Takashi Koyano, Thaworn Kowithayakorn, Masami Ishibashi
    • Journal Title

      Journal of Natural Medicines

      Volume: 74 Pages: 280-289

    • DOI

      10.1007/s11418-019-01380-x

    • NAID

      40022183696

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-17H03992, KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-20H03394
  • [Journal Article] Nonactic acid derivatives isolated from Streptomyces werraensis IFM12104 in a screening program for BMI1 promoter inhibitory activity2019

    • Author(s)
      Yusuke Yokoyama, Midori A. Arai, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      Natural Products Communications

      Volume: 14 Pages: 1-5

    • DOI

      10.1177/1934578x19866583

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-17H03992
  • [Journal Article] Identification of BMI1 promoter inhibitors from Streptomyces sp. IFM-119582019

    • Author(s)
      Yusuke Yokoyama, Midori A. Arai, Yasumasa Hara, Masami Ishibashi
    • Journal Title

      Bioorganic & Medicinal Chemistry

      Volume: 27 Pages: 2998-3003

    • DOI

      10.1016/j.bmc.2019.05.002

    • Peer Reviewed
    • Data Source
      KAKENHI-PUBLICLY-19H04640, KAKENHI-PROJECT-17H03992, KAKENHI-PROJECT-18H02582
  • [Journal Article] Coculture of a pathogenic actinomycete and animal cells to produce nocarjamide, a cyclic nonapeptide with Wnt signal-activating effect2018

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Kazufumi Toume, Hyuma Masu, Tomoyuki Sato, Katsuko Komatsu, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      Organic Letters

      Volume: 20 Pages: 5831-5834

    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Journal Article] Isolation of Nabscessin C from <i>Nocardia abscessus</i> IFM 10029<sup>T</sup> and a Study on Biosynthetic Pathway for Nabscessins2018

    • Author(s)
      Shoko Hara, Yasumasa Hara, Midori A. Arai, Yoko Kusuya, Hiroki Takahashi, Takashi Yaguchi, Masami Ishibashi
    • Journal Title

      CHEMICAL & PHARMACEUTICAL BULLETIN

      Volume: 66 Issue: 10 Pages: 976-982

    • DOI

      10.1248/cpb.c18-00430

    • NAID

      130007492854

    • ISSN
      0009-2363, 1347-5223
    • Language
      English
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Journal Article] Nabscessins A and B, aminocyclitol derivatives from Nocardia abscessus IFM 10029T2017

    • Author(s)
      Shoko Hara, Naoki Ishikawa, Yasumasa Hara, Tatsuo Nehira, Kanae Sakai, Tohru Gonoi, Masami Ishibashi
    • Journal Title

      Journal of Natural Products

      Volume: 80 Pages: 565-568

    • DOI

      10.1021/acs.jnatprod.6b00935

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-16K05696, KAKENHI-PROJECT-16K14910, KAKENHI-PROJECT-17H03992
  • [Presentation] 動物細胞との共培養法による病原性放線菌Nocardia属由来新規生物活性天然物の探索 (2)2021

    • Author(s)
      原 康雅,矢口 貴志,石橋 正己
    • Organizer
      日本薬学会第141年会
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] Andrographis paniculataからの BMI1 プロモーター阻害作用を示す天然物の探索2020

    • Author(s)
      藤井一樹,荒井緑,原康雅,S. K. Sadhu,F. Ahmed,石橋正己
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] 微生物の生育環境を模倣した共培養法による新規天然物の探索2020

    • Author(s)
      千葉 まれの, 原 康雅, 石橋 正己
    • Organizer
      日本薬学会140年会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2020

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      2nd German-Japanese Joint Symposium on the Biosynthesis of Natural Products
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K16024
  • [Presentation] 関節リウマチ由来滑膜細胞に選択的にアポトーシス経路を誘導する天然物の探索2020

    • Author(s)
      山崎秀太,原康雅,小谷野喬,T. Kowithayakorn,石橋正己
    • Organizer
      第64回日本薬学会関東支部大会
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Search for new natural products from pathogenic actinomycetes of the genus Nocardia by co-culture with animal cells2020

    • Author(s)
      Yasumasa Hara, Midori A. Arai, Takashi Yaguchi, Masami Ishibashi
    • Organizer
      2nd German-Japanese Symposium on Natural Product Biosynthesis
    • Data Source
      KAKENHI-PROJECT-20H03394
  • [Presentation] Santalum album からのWnt シグナル阻害作用をもつ天然物の探索2019

    • Author(s)
      佐藤知幸,荒井緑,原康雅,益西卓瑪,小谷野喬,Thaworn Kowithayakorn,石橋正己
    • Organizer
      日本生薬学会第66回年会
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Presentation] 放線菌からのBMI1 プロモーター阻害作用をもつ天然物の探索2019

    • Author(s)
      横山夕将, 荒井緑, 原康雅, 石橋正己
    • Organizer
      第8回食品薬学シンポジウム
    • Data Source
      KAKENHI-PROJECT-17H03992
  • [Presentation] 微生物共培養法を利用した活性天然物の探索2018

    • Author(s)
      城森 啓宏, 笹岡 美歩,原 康雅,Andi Setiawan,荒井 雅吉
    • Organizer
      日本生薬学会第65回年会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • [Presentation] 微生物共培養法を利用した活性天然物の探索2018

    • Author(s)
      城森 啓宏, 原 康雅, 笹岡 美歩, Andi Setiawan, 荒井 雅吉
    • Organizer
      第68回日本薬学会近畿支部総会・大会
    • Data Source
      KAKENHI-PROJECT-19K21222
  • 1.  Ishibashi Masami (90212927)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 12 results
  • 2.  荒井 緑 (40373261)
    # of Collaborated Projects: 2 results
    # of Collaborated Products: 10 results
  • 3.  石川 直樹 (20748826)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 4.  高屋 明子 (80334217)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 0 results
  • 5.  根平 達夫
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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