Murai Kazuhisa 村居和寿

Researcher Number	10828099
Other IDs
Affiliation (Current)	2026: 金沢大学, 保健学系, 助教
Affiliation (based on the past Project Information) *help	2019 – 2024: 金沢大学, 保健学系, 助教
Review Section/Research Field	Principal Investigator Basic Section 53010:Gastroenterology-related / Basic Section 49060:Virology-related Except Principal Investigator Basic Section 53010:Gastroenterology-related / Medium-sized Section 49:Pathology, infection/immunology, and related fields
Keywords	Principal Investigator B型肝炎ウイルス / 腫瘍免疫 / がん微小環境 / 免疫チェックポイント阻害剤 / 肝がん / 肝臓 / ウイルス感染 / 肝炎ウイルス / B型肝炎 / C型肝炎 / 感染症 / 自然免疫 / C型肝炎ウイルス … More Except Principal Investigator … More B型肝炎ウイルス / 抗ウイルス薬 / D型肝炎ウイルス / 肝硬変 / 肝がん / ウイルス性肝炎 Less

新規モニタリング法の確立によるB型肝炎ウイルスを完全駆除する薬物の探索と同定
- Principal Investigator
  
  島上哲朗
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University
Functional analysis of host factors that regulate hepatitis B virus RNAPrincipal Investigator
- Principal Investigator
  
  村居和寿
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 49060:Virology-related
- Research Institution
  Kanazawa University
Elucidation of liver tumor microenvironment by single-cell multi-omics analysisPrincipal Investigator
- Principal Investigator
  
  Murai Kazuhisa
- Project Period (FY)
  2022 – 2023
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University
Investigation on Molecular Mechanisms of Liver Diseases Caused by Hepatitis B and D Viruses Coinfection
- Principal Investigator
  
  Shimakami Tetsuro
- Project Period (FY)
  2020 – 2024
- Research Category
  
  Fund for the Promotion of Joint International Research (Fostering Joint International Research (B))
- Review Section
  
  Medium-sized Section 49:Pathology, infection/immunology, and related fields
- Research Institution
  Kanazawa University
Identification of a host RNA decoy to RIG-I using RIP-Seq method and application to oligonucleotide therapeuticsPrincipal Investigator
- Principal Investigator
  
  Murai Kazuhisa
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53010:Gastroenterology-related
- Research Institution
  Kanazawa University

All 2025 2024 2023 2022 2019

All Journal Article Presentation

[Journal Article] Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection2025
- Author(s)
  Ide Mayuko、Tabata Noriko、Murai Kazuhisa、Yonemura Yuko、Wang Ying、Ishida Atsuya、Shirasaki Takayoshi、Kaneko Shuichi、Ito Satoru、Honda Masao、Yanagawa Hiroshi
- Journal Title
  
  FEBS Letters
  
  Volume: - Issue: 9 Pages: 1285-1298
- DOI
  10.1002/1873-3468.15101
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K10244
[Journal Article] Roles Played by DOCK11, a Guanine Nucleotide Exchange Factor, in HBV Entry and Persistence in Hepatocytes2024
- Author(s)
  Li Ying-Yi、Murai Kazuhisa、Lyu Junyan、Honda Masao
- Journal Title
  
  Viruses
  
  Volume: 16 Issue: 5 Pages: 745-745
- DOI
  10.3390/v16050745
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-24K10244, KAKENHI-PROJECT-24K11086
[Journal Article] Nucleos(t)ide analogs for hepatitis B virus infection differentially regulate the growth factor signaling in hepatocytes2024
- Author(s)
  Shimizu Ryogo、Murai Kazuhisa、Tanaka Kensuke、Sato Yuga、Takeda Naho、Nakasyo Saki、Shirasaki Takayoshi、Kawaguchi Kazunori、Shimakami Tetsuro、Nio Kouki、Nakaya Yuki、Kagiwada Harumi、Horimoto Katsuhisa、Mizokami Masashi、Kaneko Shuichi、Murata Kazumoto、Yamashita Taro、Honda Masao
- Journal Title
  
  Hepatology Communications
  
  Volume: 8 Issue: 1 Pages: 0351-0351
- DOI
  10.1097/hc9.0000000000000351
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-21H04823, KAKENHI-PROJECT-20KK0178, KAKENHI-PROJECT-23K27581
[Journal Article] High-Throughput Screening of Antiviral Compounds Using a Recombinant Hepatitis B Virus and Identification of a Possible Infection Inhibitor, Skimmianine2024
- Author(s)
  (1)Yoshita M, Funaki M, Shimakami T, Kakuya M, Murai K, Sugimoto S, Kawase S, Matsumori K, Kawane T, Nishikawa T, Nakamura A, Suzuki R, Ishida A, Kawasaki N, Sato Y, Li YY, Sumiyadorj A, Nio K, Takatori H, Kawaguchi K, Kuroki K, Kato T, Honda M, Yamashita T.
- Journal Title
  
  Viruses
  
  Volume: 16 Issue: 8 Pages: 1346-1346
- DOI
  10.3390/v16081346
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-20KK0178, KAKENHI-PROJECT-23K27581, KAKENHI-PROJECT-24K10244, KAKENHI-PROJECT-24K18968
[Journal Article] A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes2022
- Author(s)
  Sumiyadorj Ariunaa、Murai Kazuhisa、Shimakami Tetsuro、Kuroki Kazuyuki、Nishikawa Tomoki、Kakuya Masaki、Yamada Atsumu、Wang Ying、Ishida Atsuya、Shirasaki Takayoshi、Kawase Shotaro、Li Ying‐Yi、Okada Hikari、Nio Kouki、Kawaguchi Kazunori、Honda Masao、Kaneko Shuichi
- Journal Title
  
  Hepatology Communications
  
  Volume: 6 Issue: 9 Pages: 2441-2454
- DOI
  10.1002/hep4.2018
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-21K07940, KAKENHI-PROJECT-20KK0178
[Journal Article] Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.2019
- Author(s)
  Murai K, Honda M, Shirasaki T, Shimakami T, Omura H, Misu H, Kita Y, Takeshita Y, Ishii KA, Takamura T, Urabe T, Shimizu R, Okada H, Yamashita T, Sakai Y, Kaneko S.
- Journal Title
  
  Cell Host Microbe
  
  Volume: 10;25(4) Issue: 4 Pages: 588-601
- DOI
  10.1016/j.chom.2019.02.015
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K15933, KAKENHI-PROJECT-18K08507, KAKENHI-PROJECT-19K08975, KAKENHI-PROJECT-18K19560, KAKENHI-PROJECT-19K17427, KAKENHI-PLANNED-17H06393, KAKENHI-PROJECT-17H04199, KAKENHI-PROJECT-18H02793, KAKENHI-PROJECT-16K09739, KAKENHI-PROJECT-16K09740, KAKENHI-PROJECT-17K09413
[Presentation] Identification of the Netrin-1 as a gene that regulates HBV entry2024
- Author(s)
  Kazuhisa Murai, Ying Wang, Atsuya Ishida, Ying-Yi Li, Mayuko Ide, Noriko Tabata, Satoru Ito, Hiroshi Yanagawa, Suemizu Hiroshi, Tetsuro Shimakami, Taro Yamashita, Masao Honda
- Organizer
  International HBV Meeting 2024
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-24K10244
[Presentation] HBV細胞内侵入を制御する宿主因子の同定とその機能解析2024
- Author(s)
  村居和寿、山下太郎、本多政夫
- Organizer
  第60回　日本肝臓学会総会
- Data Source
  KAKENHI-PROJECT-24K10244
[Presentation] 肝がん細胞代謝制御因子による腫瘍免疫抑制機序の解析2023
- Author(s)
  村居和寿、山下太郎、本多政夫
- Organizer
  JDDW2023
- Data Source
  KAKENHI-PROJECT-22K16037
[Presentation] Induction of selenoprotein P mRNA during hepatitis C virus infection inhibits RIG-I-mediated antiviral immunity2019
- Author(s)
  Kazuhisa Murai, Masao Honda, Tetsuro Shimakami, Takayoshi Shirasaki, Hirofumi Misu, Toshinari Takamura, Seishi Murakami, Shuichi Kaneko
- Organizer
  AASLD2019
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K17427

1. Shimakami Tetsuro (50436820)

# of Collaborated Projects: 2 results

# of Collaborated Products: 1 results
2. 善岡克次 (60200937)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
3. 山下太郎 (90377432)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results
4. KAWAGUCHI Kazunori

# of Collaborated Projects: 0 results

# of Collaborated Products: 2 results
5. 本多政夫

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results
6. 岡田光

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Murai Kazuhisa 村居 和寿

Research Projects

Research Products

Co-Researchers

新規モニタリング法の確立によるB型肝炎ウイルスを完全駆除する薬物の探索と同定

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Functional analysis of host factors that regulate hepatitis B virus RNAPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of liver tumor microenvironment by single-cell multi-omics analysisPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation on Molecular Mechanisms of Liver Diseases Caused by Hepatitis B and D Viruses Coinfection

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Identification of a host RNA decoy to RIG-I using RIP-Seq method and application to oligonucleotide therapeuticsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Endothelial lipase‐binding peptides similar to netrin‐1 inhibit hepatitis B virus infection2025

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Roles Played by DOCK11, a Guanine Nucleotide Exchange Factor, in HBV Entry and Persistence in Hepatocytes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Nucleos(t)ide analogs for hepatitis B virus infection differentially regulate the growth factor signaling in hepatocytes2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] High-Throughput Screening of Antiviral Compounds Using a Recombinant Hepatitis B Virus and Identification of a Possible Infection Inhibitor, Skimmianine2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A single hepatitis B virus genome with a reporter allows the entire viral life cycle to be monitored in primary human hepatocytes2022

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Induction of Selenoprotein P mRNA during Hepatitis C Virus Infection Inhibits RIG-I-Mediated Antiviral Immunity.2019

Author(s)

Journal Title

DOI

Data Source

[Presentation] Identification of the Netrin-1 as a gene that regulates HBV entry2024

Author(s)

Organizer

Data Source

[Presentation] HBV細胞内侵入を制御する宿主因子の同定とその機能解析2024

Author(s)

Organizer

Data Source

[Presentation] 肝がん細胞代謝制御因子による腫瘍免疫抑制機序の解析2023

Author(s)

Organizer

Data Source

[Presentation] Induction of selenoprotein P mRNA during hepatitis C virus infection inhibits RIG-I-mediated antiviral immunity2019

Author(s)

Organizer

Data Source

Murai Kazuhisa 村居和寿