kimishima aoi 君嶋葵

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Kimishima Aoi 君嶋葵

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Researcher Number	10832404
Other IDs
Affiliation (Current)	2025: 北里大学, 感染制御科学府, 講師
Affiliation (based on the past Project Information) *help	2025: 北里大学, 感染制御科学府, 講師 2020 – 2024: 北里大学, 感染制御科学府, 助教 2023: 北里大学, 感染制御科学府, 講師
Review Section/Research Field	Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related / Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related Except Principal Investigator Basic Section 47050:Environmental and natural pharmaceutical resources-related
Keywords	Principal Investigator マクロライド / 薬剤耐性 / グラム陰性菌 / 天然物 / 抗感染症薬 / 三型分泌機構 / グラム陰性細菌 / 化合物ライブラリー構築 / 構造活性相関研究 / エバーメクチン / 創薬化学 / ケミカルライブラリー / 全合成 … More Except Principal Investigator … More 天然化合物 / 増強活性物質 / マクロライド / 多剤耐性菌 / 緑膿菌 / 微生物由来 / MRSA / 生物活性物質 / 薬剤耐性因子 Less

16員環マクロライドを基盤とした広域抗グラム陰性細菌剤の創製研究Principal Investigator
- Principal Investigator
  
  君嶋葵
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
緑膿菌感染症治療に有効な5-o-mycaminosyltylonolide (OMT) 増強活性物質の創製
- Principal Investigator
  
  本庄雅子
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
新規作用機序を有する抗感染症薬創製に向けたグラム陰性細菌三型分泌機構阻害剤の開発Principal Investigator
- Principal Investigator
  
  君嶋葵
- Project Period (FY)
  2023 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
Discovery of microorganism-derived anti-MRSA therapeutic seed compounds that inhibit drug resistance factors
- Principal Investigator
  
  Asami Yukihiro
- Project Period (FY)
  2021 – 2023
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 47050:Environmental and natural pharmaceutical resources-related
- Research Institution
  Kitasato University
Establishment of a Convergent Synthesis of Omura Natural Products Evermectins with Novel Structures and Biological ActivitiesPrincipal Investigator
- Principal Investigator
  
  Kimishima Aoi
- Project Period (FY)
  2020 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47010:Pharmaceutical chemistry and drug development sciences-related
- Research Institution
  Kitasato University

All 2024 2023

All Journal Article Presentation

[Journal Article] The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus2024
- Author(s)
  Honsho Masako、Kimishima Aoi、Ikeda Akari、Iwatsuki Masato、Nonaka Kenichi、Matsui Hidehito、Hanaki Hideaki、Asami Yukihiro、Sunazuka Toshiaki
- Journal Title
  
  The Journal of Antibiotics
  
  Volume: 77 Issue: 3 Pages: 185-188
- DOI
  10.1038/s41429-023-00691-2
- Data Source
  KAKENHI-PROJECT-21K06616
[Journal Article] A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria2024
- Author(s)
  Kimishima Aoi、Tsuruoka Iori、Tsutsumi Hayama、Honsho Masako、Honma Sota、Matsui Hidehito、Sugamata Miho、Wasuwanich Paul、Inahashi Yuki、Hanaki Hideaki、Asami Yukihiro
- Journal Title
  
  Chemistry & Biodiversity
  
  Volume: 21 Issue: 2
- DOI
  10.1002/cbdv.202301834
- Data Source
  KAKENHI-PROJECT-22K15305, KAKENHI-PROJECT-21K06616
[Journal Article] Rediscovery of tetronomycin as a broad-spectrum and potent antibiotic against drug-resistant Gram-positive bacteria2023
- Author(s)
  Aoi Kimishima, Iori Tsuruoka, Hiroki Kanto, Hayama Tsutsumi, Naoaki Arima, Kazunari Sakai, Miho Sugamata, Hidehito Matsui, Yoshihiro Watanabe, Masato Iwatsuki, Masako Honsho, Kamrun Naher, Yuki Inahashi, Hideaki Hanaki, Yukihiro Asami
- Journal Title
  
  ACS Omega
  
  Volume: 8 Issue: 12 Pages: 11556-11563
- DOI
  10.1021/acsomega.3c00651
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-21K06616, KAKENHI-PROJECT-22K15305
[Presentation] 薬剤耐性グラム陽性細菌に対する広域かつ強力な抗菌活性を示すテトロノマイシンの再発見2023
- Author(s)
  鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 稲橋佑起, 花木秀明, 浅見行弘
- Organizer
  日本農芸化学会2023年度大会 2023年3月15日
- Data Source
  KAKENHI-PROJECT-21K06616
[Presentation] 抗薬剤耐性グラム陽性細菌物質テトロノマイシンの再発見とその作用機序解析2023
- Author(s)
  鶴岡伊織, 君嶋葵, 菅藤裕貴, 堤隼馬, 有馬直明, 酒井一成, 菅又美穂, 松井秀仁, 渡邊善洋, 岩月正人, 本庄雅子, Naher Kamrun, 本間颯太, 稲橋佑起, 花木秀明, 浅見行弘
- Organizer
  第65回天然有機化合物討論会　2023年9月4日
- Data Source
  KAKENHI-PROJECT-21K06616

1. 本庄雅子 (50870581)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
2. 松井秀仁 (80503797)

# of Collaborated Projects: 2 results

# of Collaborated Products: 0 results
3. Asami Yukihiro (70391844)

# of Collaborated Projects: 1 results

# of Collaborated Products: 4 results
4. 堤隼馬

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

kimishima aoi 君嶋 葵

Kimishima Aoi 君嶋 葵

Research Projects

Research Products

Co-Researchers

16員環マクロライドを基盤とした広域抗グラム陰性細菌剤の創製研究Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

緑膿菌感染症治療に有効な5-o-mycaminosyltylonolide (OMT) 増強活性物質の創製

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

新規作用機序を有する抗感染症薬創製に向けたグラム陰性細菌三型分泌機構阻害剤の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Discovery of microorganism-derived anti-MRSA therapeutic seed compounds that inhibit drug resistance factors

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Establishment of a Convergent Synthesis of Omura Natural Products Evermectins with Novel Structures and Biological ActivitiesPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] The potentiation activity of β-lactam by phomoidrides and oxasetin against methicillin-resistant Staphylococcus aureus2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] A new tetronomycin analog, broad‐spectrum and potent antibiotic against drug‐resistant Gram‐positive bacteria2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Rediscovery of tetronomycin as a broad-spectrum and potent antibiotic against drug-resistant Gram-positive bacteria2023

Author(s)

Journal Title

DOI

Data Source

[Presentation] 薬剤耐性グラム陽性細菌に対する広域かつ強力な抗菌活性を示すテトロノマイシンの再発見2023

Author(s)

Organizer

Data Source

[Presentation] 抗薬剤耐性グラム陽性細菌物質テトロノマイシンの再発見とその作用機序解析2023

Author(s)

Organizer

Data Source

kimishima aoi 君嶋葵

Kimishima Aoi 君嶋葵