Goto Sawako 後藤佐和子

Researcher Number	10832884
Other IDs
Affiliation (Current)	2026: 東北大学, 医学イノベーション研究所, 講師 2026: 東北大学, 大学病院, 助教
Affiliation (based on the past Project Information) *help	2025: 東北大学, 大学病院, 非常勤講師 2024: 東北大学, 大学病院, 助教 2019 – 2023: 新潟大学, 医歯学総合研究科, 特任助教
Review Section/Research Field	Principal Investigator Basic Section 53040:Nephrology-related Except Principal Investigator Basic Section 53040:Nephrology-related
Keywords	Principal Investigator メガリン / レニン-アンジオテンシン系 / 腎毒性リガンド / 立体構造解析 / クライオ電子顕微鏡 / ミトコンドリア / 性差 / 腎臓病 / 近位尿細管 / LC/MS / レニン・アンジオテンシン系 / 質量分析法 / アンジオテンシンペプチド … More Except Principal Investigator … More 糖尿病性腎臓病 / 急性腎障害 / 慢性腎臓病 / バイオマーカー / SGLT2阻害薬 / in silicoスクリーニング / クライオ電子顕微鏡 / 創薬 / メガリン Less

Sex differences in the renin-angiotensin system and mitochondria in the kidney.Principal Investigator
- Principal Investigator
  
  後藤佐和子
- Project Period (FY)
  2025 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
Structural Analysis of the Binding Interaction Between Megalin and Nephrotoxic Ligands, and the Pharmacological Mechanism of Megalin AntagonistsPrincipal Investigator
- Principal Investigator
  
  Sawako Goto
- Project Period (FY)
  2022 – 2024
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Tohoku University
  Niigata University
Elucidation of kidney disease pathogenesis and development of new diagnostics and therapeutics based on detailed analysis of megalin structure and functio
- Principal Investigator
  
  Saito Akihiko
- Project Period (FY)
  2021 – 2024
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Niigata University
Investigation of the role of megalin in the renal renin-angiotensin systemPrincipal Investigator
- Principal Investigator
  
  Goto Sawako
- Project Period (FY)
  2019 – 2021
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 53040:Nephrology-related
- Research Institution
  Niigata University

All 2024 2023 2022 2020

All Journal Article Presentation Patent

[Journal Article] Cryo-EM structures elucidate the multiligand receptor nature of megalin2024
- Author(s)
  Goto Sawako、Tsutsumi Akihisa、Lee Yongchan、Hosojima Michihiro、Kabasawa Hideyuki、Komochi Koichi、Nagatoishi Satoru、Takemoto Kazuya、Tsumoto Kouhei、Nishizawa Tomohiro、Kikkawa Masahide、Saito Akihiko
- Journal Title
  
  Proceedings of the National Academy of Sciences
  
  Volume: 121 Issue: 22
- DOI
  10.1073/pnas.2318859121
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PLANNED-21H05248, KAKENHI-PROJECT-22K16213
[Journal Article] The endocytosis receptor megalin: From bench to bedside2023
- Author(s)
  Goto S, Hosojima M, Kabasawa H, Saito A
- Journal Title
  
  International Journal of Biochemistry and Cell Biology
  
  Volume: 15 Pages: 106393-106393
- DOI
  10.1016/j.biocel.2023.106393
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-23K21436
[Journal Article] Urinary A- and C-megalin predict progression of diabetic kidney disease : an exploratory retrospective cohort study2022
- Author(s)
  Iida Tomomichi、Hosojima Michihiro、Kabasawa Hideyuki、Yamamoto-Kabasawa Keiko、Goto Sawako、Tanaka Takahiro、Kitamura Nobutaka、Nakada Mitsutaka、Itoh Shino、Ogasawara Shinya、Kaseda Ryohei、Suzuki Yoshiki、Narita Ichiei、Saito Akihiko
- Journal Title
  
  Journal of Diabetes and its Complications
  
  Volume: 36 Issue: 11 Pages: 108312-108312
- DOI
  10.1016/j.jdiacomp.2022.108312
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-17K09690, KAKENHI-PROJECT-23K21436
[Patent] シクロデキストリン誘発腎障害の抑制2022
- Inventor(s)
  斎藤亮彦，後藤佐和子，細島康宏，蒲澤秀門，平山吉朗
- Industrial Property Rights Holder
  斎藤亮彦，後藤佐和子，細島康宏，蒲澤秀門，平山吉朗
- Industrial Property Rights Type
  特許
- Industrial Property Number
  2022-194619
- Filing Date
  2022
- Data Source
  KAKENHI-PROJECT-23K21436
[Presentation] 溶血関連腎症におけるメガリンの役割とその治療戦略2022
- Author(s)
  後藤佐和子，細島康宏，蒲澤秀門，成田一衛，斎藤亮彦
- Organizer
  第65回日本腎臓学会年次学術総会
- Data Source
  KAKENHI-PROJECT-23K21436
[Presentation] SGLT2阻害薬使用時における尿中メガリンおよびメガリンリガンド分子の動態2022
- Author(s)
  細島康宏、蒲澤秀門、後藤佐和子、鈴木芳樹、成田一衛、斎藤亮彦
- Organizer
  第37回日本糖尿病合併症学会
- Data Source
  KAKENHI-PROJECT-23K21436
[Presentation] 2型糖尿病患者における尿中メガリン測定による腎予後予測2022
- Author(s)
  飯田倫理，細島康宏，蒲澤秀門，蒲澤佳子，後藤佐和子，田中崇裕，北村信隆，忰田亮平，鈴木芳樹，成田一衛，斎藤亮彦
- Organizer
  第65回日本腎臓学会年次学術総会
- Data Source
  KAKENHI-PROJECT-23K21436
[Presentation] 2型糖尿病患者における尿中メガリンの腎予後予測能の検討2022
- Author(s)
  飯田倫理，細島康宏，蒲澤秀門，蒲澤佳子，後藤佐和子，田中崇裕，北村信隆，忰田亮平，鈴木芳樹，成田一衛，斎藤亮彦
- Organizer
  第65回日本糖尿病学会年次学術集会
- Data Source
  KAKENHI-PROJECT-23K21436
[Presentation] メガリンを介する腎内レニン-アンジオテンシン（Ang）系（RAS）の動的均衡化制御機構2020
- Author(s)
  後藤　佐和子，吉田　豊，細島　康宏，蒲澤　秀門，忰田　亮平，成田　一衛，斎藤　亮彦
- Organizer
  第63回（令和2年度）日本腎臓学会学術総会
- Data Source
  KAKENHI-PROJECT-19K17734

1. Saito Akihiko (80293207)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
2. 細島康宏 (50464003)

# of Collaborated Projects: 1 results

# of Collaborated Products: 6 results
3. 吉川雅英

# of Collaborated Projects: 0 results

# of Collaborated Products: 1 results

Goto Sawako 後藤 佐和子

Research Projects

Research Products

Co-Researchers

Sex differences in the renin-angiotensin system and mitochondria in the kidney.Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Structural Analysis of the Binding Interaction Between Megalin and Nephrotoxic Ligands, and the Pharmacological Mechanism of Megalin AntagonistsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of kidney disease pathogenesis and development of new diagnostics and therapeutics based on detailed analysis of megalin structure and functio

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Investigation of the role of megalin in the renal renin-angiotensin systemPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Cryo-EM structures elucidate the multiligand receptor nature of megalin2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] The endocytosis receptor megalin: From bench to bedside2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Urinary A- and C-megalin predict progression of diabetic kidney disease : an exploratory retrospective cohort study2022

Author(s)

Journal Title

DOI

Data Source

[Patent] シクロデキストリン誘発腎障害の抑制2022

Inventor(s)

Industrial Property Rights Holder

Industrial Property Rights Type

Industrial Property Number

Filing Date

Data Source

[Presentation] 溶血関連腎症におけるメガリンの役割とその治療戦略2022

Author(s)

Organizer

Data Source

[Presentation] SGLT2阻害薬使用時における尿中メガリンおよびメガリンリガンド分子の動態2022

Author(s)

Organizer

Data Source

[Presentation] 2型糖尿病患者における尿中メガリン測定による腎予後予測2022

Author(s)

Organizer

Data Source

[Presentation] 2型糖尿病患者における尿中メガリンの腎予後予測能の検討2022

Author(s)

Organizer

Data Source

[Presentation] メガリンを介する腎内レニン-アンジオテンシン（Ang）系（RAS）の動的均衡化制御機構2020

Author(s)

Organizer

Data Source

Goto Sawako 後藤佐和子