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Zhang Xinjian  張 心健

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… Alternative Names

張 心健  チョウ シンケン

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Researcher Number 10850430
Affiliation (Current) 2026: 藤田医科大学, 精神・神経病態解明センター, 助教
Affiliation (based on the past Project Information) *help 2026: 藤田医科大学, 精神・神経病態解明センター, 助教
2024: 藤田医科大学, 精神・神経病態解明センター, 助教
2020: 藤田医科大学, その他部局等, 助教
2019: 名古屋大学, 医学系研究科, 研究員
Review Section/Research Field
Principal Investigator
Basic Section 47040:Pharmacology-related / 0704:Neuroscience, brain sciences, and related fields
Except Principal Investigator
Basic Section 48030:Pharmacology-related
Keywords
Principal Investigator
medium spiny neurons / nucleus accumbens / potassium channels / drug addiction / neuronal excitability / medium spiny neuron / potassium channel / cocaine / addcition / 脳神経回路 … More / 細胞内シグナル伝達 / RhoA/Rho-kinase / 行動解析 / ノックアウトマウス / リン酸化 / 脳機能 / Rho-kinase / Rho … More
Except Principal Investigator
意思決定 / 副作用 / パーキンソン病 Less
  • Research Projects

    (4 results)
  • Research Products

    (7 results)
  • Co-Researchers

    (3 People)
  •  Dissecting schizophrenia mechanisms via GEF-H1 using mouse modelsPrincipal Investigator

    • Principal Investigator
      張 心健
    • Project Period (FY)
      2026 – 2028
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Fujita Health University
  •  パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発

    • Principal Investigator
      永井 拓
    • Project Period (FY)
      2024 – 2026
    • Research Category
      Grant-in-Aid for Scientific Research (B)
    • Review Section
      Basic Section 48030:Pharmacology-related
    • Research Institution
      Fujita Health University
  •  Development of new therapeutic drugs for drug addiction targeting potassium channelsPrincipal Investigator

    • Principal Investigator
      張 心健
    • Project Period (FY)
      2024 – 2025
    • Research Category
      Grant-in-Aid for Early-Career Scientists
    • Review Section
      Basic Section 47040:Pharmacology-related
    • Research Institution
      Fujita Health University
  •  Elucidation of the brain function and the molecular mechanisms of RhoA/Rho-kinase signaling in neural circuitsPrincipal Investigator

    • Principal Investigator
      Zhang Xinjian
    • Project Period (FY)
      2019 – 2020
    • Research Category
      Grant-in-Aid for Research Activity Start-up
    • Review Section
      0704:Neuroscience, brain sciences, and related fields
    • Research Institution
      Fujita Health University
      Nagoya University

All 2024 2020 2019

All Journal Article Presentation

  • [Journal Article] リン酸化シグナル解析を基盤とした薬物依存症の分子機序の解明2024

    • Author(s)
      張 心健、貝淵 弘三、永井 拓
    • Journal Title

      Farumashia

      Volume: 60 Issue: 11 Pages: 1030-1034

    • DOI

      10.14894/faruawpsj.60.11_1030

    • ISSN
      0014-8601, 2189-7026
    • Language
      Japanese
    • Peer Reviewed
    • Data Source
      KAKENHI-PROJECT-24K18291
  • [Journal Article] Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson’s Disease2024

    • Author(s)
      Kubota Hisayoshi、Zhou Xinzhu、Zhang Xinjian、Watanabe Hirohisa、Nagai Taku
    • Journal Title

      International Journal of Molecular Sciences

      Volume: 25 Issue: 16 Pages: 8849-8849

    • DOI

      10.3390/ijms25168849

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-24K02218, KAKENHI-PROJECT-24K18223, KAKENHI-PROJECT-24K18291
  • [Journal Article] Signal flow in the NMDA receptor?dependent phosphoproteome regulates postsynaptic plasticity for aversive learning2024

    • Author(s)
      Funahashi Y, Ahammad RU, Zhang X, Hossen E, Kawatani M, Nakamuta S, Yoshimi A, Wu M, Wang H, Wu M, Li X, Faruk MO, Shohag MH, Lin YH, Tsuboi D, Nishioka T, Kuroda K, Amano M, Noda Y, Yamada K, Sakimura K, Nagai T, Yamashita T, Uchino S, Kaibuchi K.
    • Journal Title

      Science Signaling

      Volume: 17 Issue: 853

    • DOI

      10.1126/scisignal.ado9852

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-21K06427, KAKENHI-PROJECT-21K06428, KAKENHI-PROJECT-23K27360, KAKENHI-PROJECT-24K02138, KAKENHI-PROJECT-24K02218, KAKENHI-PROJECT-22K06755, KAKENHI-PROJECT-24K09854, KAKENHI-PROJECT-24K18291
  • [Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020

    • Author(s)
      Lin, Y-H., Yamahashi, Y., Kuroda, K., Faruk M. O., Zhang, X., Yamada, K., Yamanaka, A., Nagai, T., Kaibuchi, K.
    • Journal Title

      Neurocham. Int.

      Volume: 143 Pages: 104935-104935

    • DOI

      10.1016/j.neuint.2020.104935

    • Peer Reviewed / Open Access / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05016, KAKENHI-PUBLICLY-19H05209, KAKENHI-PUBLICLY-20H05061, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K23774
  • [Presentation] ドーパミンの細胞内シグナル解析から新規依存症治療薬の開発2024

    • Author(s)
      張心健、周昕竹、窪田悠力、永井拓
    • Organizer
      情動研究会 2024
    • Data Source
      KAKENHI-PROJECT-24K18291
  • [Presentation] Pharmacological study on the effects of opioid receptor antagonist-containing abuse-deterrent formulations2024

    • Author(s)
      Xinjian Zhang, Kiyoyuki Kitaichi, Kiyofumi Yamada, Taku Nagai
    • Organizer
      NEURO2024
    • Data Source
      KAKENHI-PROJECT-24K18291
  • [Presentation] Dopamine and adenosine signaling pathways are analyzed in striatal medium spiny neurons using kinase-associated neural phospho-signaling (KANPHOS) database2019

    • Author(s)
      Xinjian Zhang, Taku Nagai, Keisuke Kuroda, Kozo Kaibuchi
    • Organizer
      SfN 2019 第49回ニューロサイエンス会議
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K23774
  • 1.  永井 拓 (10377426)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 2 results
  • 2.  窪田 悠力 (00853227)
    # of Collaborated Projects: 1 results
    # of Collaborated Products: 1 results
  • 3.  黒田 啓介
    # of Collaborated Projects: 0 results
    # of Collaborated Products: 1 results

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