Zhang Xinjian 張心健

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張心健チョウシンケン

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Researcher Number	10850430
Affiliation (Current)	2026: 藤田医科大学, 精神・神経病態解明センター, 助教
Affiliation (based on the past Project Information) *help	2026: 藤田医科大学, 精神・神経病態解明センター, 助教 2024: 藤田医科大学, 精神・神経病態解明センター, 助教 2020: 藤田医科大学, その他部局等, 助教 2019: 名古屋大学, 医学系研究科, 研究員
Review Section/Research Field	Principal Investigator Basic Section 47040:Pharmacology-related / 0704:Neuroscience, brain sciences, and related fields Except Principal Investigator Basic Section 48030:Pharmacology-related
Keywords	Principal Investigator knockout mice / behavior tests / GEF-H1 / schizophrenia / medium spiny neurons / nucleus accumbens / potassium channels / drug addiction / neuronal excitability / medium spiny neuron … More / potassium channel / cocaine / addcition / 脳神経回路 / 細胞内シグナル伝達 / RhoA/Rho-kinase / 行動解析 / ノックアウトマウス / リン酸化 / 脳機能 / Rho-kinase / Rho … More Except Principal Investigator 意思決定 / 副作用 / パーキンソン病 Less

Dissecting schizophrenia mechanisms via GEF-H1 using mouse modelsPrincipal Investigator
- Principal Investigator
  
  張心健
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fujita Health University
パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発
- Principal Investigator
  
  永井拓
- Project Period (FY)
  2024 – 2026
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 48030:Pharmacology-related
- Research Institution
  Fujita Health University
Development of new therapeutic drugs for drug addiction targeting potassium channelsPrincipal Investigator
- Principal Investigator
  
  張心健
- Project Period (FY)
  2024 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 47040:Pharmacology-related
- Research Institution
  Fujita Health University
Elucidation of the brain function and the molecular mechanisms of RhoA/Rho-kinase signaling in neural circuitsPrincipal Investigator
- Principal Investigator
  
  Zhang Xinjian
- Project Period (FY)
  2019 – 2020
- Research Category
  
  Grant-in-Aid for Research Activity Start-up
- Review Section
  
  0704:Neuroscience, brain sciences, and related fields
- Research Institution
  Fujita Health University
  Nagoya University

All 2024 2020 2019 Other

All Journal Article Presentation Other

[Journal Article] リン酸化シグナル解析を基盤とした薬物依存症の分子機序の解明2024
- Author(s)
  張心健、貝淵弘三、永井拓
- Journal Title
  
  Farumashia
  
  Volume: 60 Issue: 11 Pages: 1030-1034
- DOI
  10.14894/faruawpsj.60.11_1030
- ISSN
  0014-8601, 2189-7026
- Language
  Japanese
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-24K18291
[Journal Article] Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson’s Disease2024
- Author(s)
  Kubota Hisayoshi、Zhou Xinzhu、Zhang Xinjian、Watanabe Hirohisa、Nagai Taku
- Journal Title
  
  International Journal of Molecular Sciences
  
  Volume: 25 Issue: 16 Pages: 8849-8849
- DOI
  10.3390/ijms25168849
- Peer Reviewed / Open Access
- Data Source
  KAKENHI-PROJECT-24K02218, KAKENHI-PROJECT-24K18223, KAKENHI-PROJECT-24K18291
[Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020
- Author(s)
  Lin, Y-H., Yamahashi, Y., Kuroda, K., Faruk M. O., Zhang, X., Yamada, K., Yamanaka, A., Nagai, T., Kaibuchi, K.
- Journal Title
  
  Neurocham. Int.
  
  Volume: 143 Pages: 104935-104935
- DOI
  10.1016/j.neuint.2020.104935
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K07082, KAKENHI-PROJECT-20K07965, KAKENHI-PROJECT-18K14816, KAKENHI-PROJECT-19K16370, KAKENHI-PROJECT-18KK0223, KAKENHI-PUBLICLY-19H05016, KAKENHI-PUBLICLY-19H05209, KAKENHI-PUBLICLY-20H05061, KAKENHI-PROJECT-17H01380, KAKENHI-PROJECT-18H02523, KAKENHI-PROJECT-19K23774
[Presentation] ドーパミンの細胞内シグナル解析から新規依存症治療薬の開発2024
- Author(s)
  張心健、周昕竹、窪田悠力、永井拓
- Organizer
  情動研究会 2024
- Data Source
  KAKENHI-PROJECT-24K18291
[Presentation] Pharmacological study on the effects of opioid receptor antagonist-containing abuse-deterrent formulations2024
- Author(s)
  Xinjian Zhang, Kiyoyuki Kitaichi, Kiyofumi Yamada, Taku Nagai
- Organizer
  NEURO2024
- Data Source
  KAKENHI-PROJECT-24K18291
[Presentation] Dopamine and adenosine signaling pathways are analyzed in striatal medium spiny neurons using kinase-associated neural phospho-signaling (KANPHOS) database2019
- Author(s)
  Xinjian Zhang, Taku Nagai, Keisuke Kuroda, Kozo Kaibuchi
- Organizer
  SfN 2019　第49回ニューロサイエンス会議
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-19K23774
[]

1. 永井拓 (10377426)

# of Collaborated Projects: 1 results

# of Collaborated Products: 2 results
2. 窪田悠力 (00853227)

# of Collaborated Projects: 1 results

# of Collaborated Products: 1 results

Zhang Xinjian 張 心健

張 心健 チョウ シンケン

Research Projects

Research Products

Co-Researchers

Dissecting schizophrenia mechanisms via GEF-H1 using mouse modelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

パーキンソン病における意思決定障害の分子・神経メカニズム解明と新規治療薬開発

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of new therapeutic drugs for drug addiction targeting potassium channelsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Elucidation of the brain function and the molecular mechanisms of RhoA/Rho-kinase signaling in neural circuitsPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] リン酸化シグナル解析を基盤とした薬物依存症の分子機序の解明2024

Author(s)

Journal Title

DOI

ISSN

Language

Data Source

[Journal Article] Pramipexole Hyperactivates the External Globus Pallidus and Impairs Decision-Making in a Mouse Model of Parkinson’s Disease2024

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Accumbal D2R-medium spiny neurons regulate aversive behaviors through PKA-Rap1 pathway.2020

Author(s)

Journal Title

DOI

Data Source

[Presentation] ドーパミンの細胞内シグナル解析から新規依存症治療薬の開発2024

Author(s)

Organizer

Data Source

[Presentation] Pharmacological study on the effects of opioid receptor antagonist-containing abuse-deterrent formulations2024

Author(s)

Organizer

Data Source

[Presentation] Dopamine and adenosine signaling pathways are analyzed in striatal medium spiny neurons using kinase-associated neural phospho-signaling (KANPHOS) database2019

Author(s)

Organizer

Data Source

[]

Zhang Xinjian 張心健

張心健チョウシンケン