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Takahashi Chihiro  野崎 千尋

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Nozaki Chihiro  野崎 千尋

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Researcher Number 10867295
Affiliation (Current) 2026: 早稲田大学, 理工学術院, 准教授(任期付)
Affiliation (based on the past Project Information) *help 2020 – 2025: 早稲田大学, 理工学術院, 准教授(任期付)
Review Section/Research Field
Principal Investigator
Basic Section 59040:Nutrition science and health science-related / Biological Sciences
Keywords
Principal Investigator
末梢神経障害 / CB2受容体欠損マウス / カンナビノイド / 高脂肪食 / 内因性カンナビノイド / 自然免疫応答 / ケモカイン受容体 / 肥満 / 慢性炎症 / CB2受容体
  • Research Projects

    (2 results)
  • Research Products

    (35 results)
  •  CB2受容体がもつ炎症「促進」と「抑制」の二面性を骨髄細胞分化から解明するPrincipal Investigator

    • Principal Investigator
      野崎 千尋
    • Project Period (FY)
      2025 – 2027
    • Research Category
      Grant-in-Aid for Scientific Research (C)
    • Review Section
      Basic Section 59040:Nutrition science and health science-related
    • Research Institution
      Waseda University
  •  Unraveling novel molecular, neural, and immune mechanisms related to chronic inflammation induced by obesityPrincipal Investigator

    • Principal Investigator
      Nozaki Chihiro
    • Project Period (FY)
      2020 – 2024
    • Research Category
      Fund for the Promotion of Joint International Research (Home-Returning Researcher Development Research)
    • Review Section
      Biological Sciences
    • Research Institution
      Waseda University

All 2024 2023 2022 2020

All Journal Article Presentation

  • [Journal Article] A Cellulose-Rich Diet Disrupts Gut Homeostasis and Leads to Anxiety through the Gut-Brain Axis2024

    • Author(s)
      Ito Kaede、Hosoki Haruka、Kasai Yuya、Sasaki Hiroyuki、Haraguchi Atsushi、Shibata Shigenobu、Nozaki Chihiro
    • Journal Title

      ACS Pharmacology & Translational Science

      Volume: 7 Issue: 10 Pages: 3071-3085

    • DOI

      10.1021/acsptsci.4c00270

    • Peer Reviewed / Open Access
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Cannabinoid CB2 receptors enhance high-fat diet evoked peripheral neuroinflammation2024

    • Author(s)
      Hosoki Haruka、Asahi Toru、Nozaki Chihiro
    • Journal Title

      Life Sciences

      Volume: 355 Pages: 123002-123002

    • DOI

      10.1016/j.lfs.2024.123002

    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] “Inhibitory” Cannabinoid CB2 receptors have “Excitatory” role to high-fat diet evoked systemic inflammatory response2023

    • Author(s)
      Nozaki Chihiro、Hosoki Haruka、Zimmer Andreas
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 97 Issue: 0 Pages: 3-B-O09-5

    • DOI

      10.1254/jpssuppl.97.0_3-B-O09-5

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Potential of Beta Caryophyllene (BCP) as the treatment for allergic responses through CB2 receptor activation2023

    • Author(s)
      Haruka Hosoki、Nozaki Chihiro、Asahi Toru
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 97 Issue: 0 Pages: 1-B-SS05-3

    • DOI

      10.1254/jpssuppl.97.0_1-B-SS05-3

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Primary culture of neurons derived from lactating mice to elucidate the contribution of the endocannabinoid system to neurodevelopment during lactation2023

    • Author(s)
      Yuya Kasai、Nozaki Chihiro
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 97 Issue: 0 Pages: 2-B-P-103

    • DOI

      10.1254/jpssuppl.97.0_2-B-P-103

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Cellulose rich food induces intestinal disturbance that leads anxiety-like behavior and amygdalar dopaminergic hyperactivity.2023

    • Author(s)
      Kaede Ito、Shibata Shigenobu、Nozaki Chihiro
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 97 Issue: 0 Pages: 3-B-P-079

    • DOI

      10.1254/jpssuppl.97.0_3-B-P-079

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] FROUNT-mediated pain control of Anti-alcoholism drug disulfiram2023

    • Author(s)
      Matsuura Kota、Terashima Yuya、Fujizuka Ryoji、Hayashi Tasuku、Ohta Arisa、Nagai Kosei、Yamada Daisuke、Makino Kosho、Takahashi Hideyo、Nozaki Chihiro、Matsushima Koji、Saitoh Akiyoshi
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 97 Issue: 0 Pages: 2-B-SS07-4

    • DOI

      10.1254/jpssuppl.97.0_2-B-SS07-4

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Bipolar effect of cannabinoid CB2 receptors to peripheral neuroinflammation2022

    • Author(s)
      Nozaki Chihiro、Zimmer Andreas、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 3-B-O11-2

    • DOI

      10.1254/jpssuppl.96.0_3-B-O11-2

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Establishment of the novel method to culture primary neurons from aged rodent brain2022

    • Author(s)
      Yuya Kasai、Nozaki Chihiro、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 2-B-P-115

    • DOI

      10.1254/jpssuppl.96.0_2-B-P-115

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] カンナビノイド受容体が無くなると、我々の身体は一体どうなってしまうのか?2022

    • Author(s)
      野崎 千尋、アンドレアス ジマー、柴田 重信
    • Journal Title

      Annual Scientific Meeting of The Japanese Society of Clinical Pharmacology and Therapeutics

      Volume: 43 Issue: 0 Pages: 3-C-S31-2

    • DOI

      10.50993/jsptsuppl.43.0_3-C-S31-2

    • ISSN
      2436-5580
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Involvement of cannabinoid receptor type 2 (CB2) to dendritic cell population on inflammatory and allergic response2022

    • Author(s)
      Hosoki Haruka、Nozaki Chihiro、Furutani Akiko、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 1-B-SS06-5

    • DOI

      10.1254/jpssuppl.96.0_1-B-SS06-5

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] The Use of an Amyloid beta Intracerebroventricular Model to Investigate the Interaction between Alzheimer‘s Disease and Circadian Dysfunction2022

    • Author(s)
      Lovell Lyndah、Nozaki Chihiro、Tahara Yu、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 3-B-SS14-2

    • DOI

      10.1254/jpssuppl.96.0_3-B-SS14-2

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Can Cannabidiol affect the peripheral circadian clockin PER2::LUC mice?2022

    • Author(s)
      Wang Hsiao Hsieh、Nozaki Chihiro、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 1-B-SS03-2

    • DOI

      10.1254/jpssuppl.96.0_1-B-SS03-2

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Cellulose rich food induces intestinal disturbance, anxiety-like behavior and amygdalar dopaminergic hyperactivity in mice.2022

    • Author(s)
      Kaede Ito、Haraguchi Atsushi、Nozaki Chihiro、Shibata Shigenobu
    • Journal Title

      Proceedings for Annual Meeting of The Japanese Pharmacological Society

      Volume: 96 Issue: 0 Pages: 3-B-SS13-5

    • DOI

      10.1254/jpssuppl.96.0_3-B-SS13-5

    • ISSN
      2435-4953
    • Language
      Japanese
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Journal Article] Age-dependent Alteration in Mitochondrial Dynamics and Autophagy in Hippocampal Neuron of Cannabinoid CB1 Receptor-deficient Mice2020

    • Author(s)
      Kosuke Kataoka, Andras Bilkei-Gorzo, Chihiro Nozaki, Akinobu Togo, Keiichiro Nakamura, Keisuke Ohta, Andreas Zimmer, Toru Asahi
    • Journal Title

      Brain Research Bulletin

      Volume: 160 Pages: 40-49

    • Peer Reviewed / Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Role of Cannabinoid CB2 Receptor Signaling on the Immune Cell Differentiation2024

    • Author(s)
      Nuzat Tabassum Islam, Toru Asahi, Chihiro Nozaki
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 高セルロース食は脳腸相関を介して不安を惹起する2024

    • Author(s)
      野崎 千尋、伊東 楓、細木 春花、笠井 悠哉、佐々木 裕之、原口 敦嗣、柴田 重信
    • Organizer
      第151回薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Effect of Cannabidiol on Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblast2024

    • Author(s)
      Hsiao-Hsieh Wang, Toru Asahi, Chihiro Nozaki
    • Organizer
      第151回薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 好酸球性副鼻腔炎におけるCB2作動薬βカリオフィレンの薬理作用2024

    • Author(s)
      細木春花、朝日透、野崎千尋
    • Organizer
      第151回薬理学会関東部会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] “Anti-inflammatory” cannabinoid CB2 receptors enhanced high-fat diet evoked neuroinflammation in mice2024

    • Author(s)
      Chihiro Nozaki, Haruka Hosoki
    • Organizer
      55th International Narcotic Research Conference (INRC)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Do the endocannabinoid systems contribute to maternal infection-induced psychiatric disorders?2024

    • Author(s)
      Isha Hemant Visal, Toru Asahi, Chihiro Nozaki
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Cannabinoid type 2 (CB2) receptor could be the key to solving the immune function decline at maturity age2024

    • Author(s)
      Haruka Hosoki, Toru Asahi, Chihiro Nozaki
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Effect of Cannabidiol on Circadian Clock Rhythm in PER2::LUCIFERASE Mouse Embryonic Fibroblast2024

    • Author(s)
      Hsiao-Hsieh Wang, Toru Asahi, Chihiro Nozaki
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] CB2 受容体の炎症調節機構の二面性に対する年齢の影響2024

    • Author(s)
      細木春花、朝日透、野崎千尋
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 高セルロース食は脳腸相関を介して不安を惹起する2024

    • Author(s)
      野崎千尋
    • Organizer
      APPW2025
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Cellulose rich food induces intestinal disturbance that leads anxiety-like behavior and amygdalar dopaminergic hyperactivity2024

    • Author(s)
      Ito Kaede、Hosoki Haruka、Kasai Yuya、Sasaki Hiroyuki、Haraguchi Atsushi、Shibata Shigenobu、Nozaki Chihiro
    • Organizer
      35th World Congress Collegium Internationale Neuro-Psychopharmacologium (CINP2024)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] "Inhibitory" CB2 receptors have "Exitatory" role to HFD-evoked inflammatory response2024

    • Author(s)
      Chihiro Nozaki
    • Organizer
      35th World Congress Collegium Internationale Neuro-Psychopharmacologium (CINP2024)
    • Int'l Joint Research
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] “Immunosuppressive” Cannabinoid CB2 receptors take “Immunoactive” role in high-fat diet evoked systemic inflammatory response2024

    • Author(s)
      Chihiro Nozaki, Haruka Hosoki, Andreas Zimmer
    • Organizer
      第52回日本免疫学会学術集会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 2型カンナビノイド(CB2)受容体:本当に「炎症に抗う」のか?2023

    • Author(s)
      野崎千尋
    • Organizer
      第42回日本オピオイドペプチドシンポジウム
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 2型カンナビノイド(CB2)受容体:本当に「炎症に抗う」のか?2023

    • Author(s)
      野崎千尋
    • Organizer
      日本臨床カンナビノイド学会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] How do sleep cycles affect Cannabidiol users? ~生活スタイルはCBDの用途や効果にどう影響するか?2023

    • Author(s)
      野崎千尋、Pan Chenyu
    • Organizer
      日本臨床カンナビノイド学会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] 基礎研究からみたCBDの臨床応用の可能性2023

    • Author(s)
      野崎千尋
    • Organizer
      第44回日本臨床薬理学会
    • Invited
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] CB2受容体は加齢による免疫機構変動の調節因子である2023

    • Author(s)
      細木春花、朝日透、野崎千尋
    • Organizer
      第42回日本オピオイドペプチドシンポジウム
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] Cannabinoid CB2 receptors have double-side role to peripheral neuroinflammation: What makes such a difference?2022

    • Author(s)
      野崎千尋
    • Organizer
      BPCNPNPPP4学会合同年会
    • Data Source
      KAKENHI-PROJECT-19K24693
  • [Presentation] カンナビノイドCB2受容体の持つ二面性:レプチンシグナリングを介した末梢神経炎症調節機構に対する影響を中心に2022

    • Author(s)
      野崎千尋、Andreas Zimmer、柴田重信
    • Organizer
      NEURO2022
    • Data Source
      KAKENHI-PROJECT-19K24693

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