Kikuchi Osamu 菊池理

Researcher Number	10869366
Other IDs	https://orcid.org/0000-0001-5012-5897
Affiliation (Current)	2026: 京都大学, 医学研究科, 准教授
Affiliation (based on the past Project Information) *help	2026: 京都大学, 医学研究科, 准教授 2024: 京都大学, 医学研究科, 准教授 2020 – 2023: 京都大学, 医学研究科, 助教
Review Section/Research Field	Principal Investigator Basic Section 50020:Tumor diagnostics and therapeutics-related Except Principal Investigator Basic Section 58060:Clinical nursing-related
Keywords	Principal Investigator 胃癌 / フェロトーシス / MAPK / 脂質過酸化物 / KRAS / 分子標的療法 Except Principal Investigator 効果発現メカニズム / 予防 / 化学療法に関連した認知機能障害 / がん … More / バイオマーカー / 認知トレーニング / 乳がん / 化学療法 / 認知機能障害 Less

KRAS過剰活性化が誘導するがん細胞ストレス応答と脆弱性の解明Principal Investigator
- Principal Investigator
  
  菊池理
- Project Period (FY)
  2026 – 2028
- Research Category
  
  Grant-in-Aid for Scientific Research (C)
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
Verifying the effectiveness and exploring the mechanism of cognitive training during chemotherapy for prevention of CRCI
- Principal Investigator
  
  宮下美香
- Project Period (FY)
  2024 – 2027
- Research Category
  
  Grant-in-Aid for Scientific Research (B)
- Review Section
  
  Basic Section 58060:Clinical nursing-related
- Research Institution
  Kyoto University
KRAS増幅胃癌におけるSprouty経路の機序解明と分子標的療法の開発Principal Investigator
- Principal Investigator
  
  菊池理
- Project Period (FY)
  2023 – 2025
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University
Development of ferroptosis induction therapy against KRAS altered gastric cancerPrincipal Investigator
- Principal Investigator
  
  Kikuchi Osamu
- Project Period (FY)
  2020 – 2022
- Research Category
  
  Grant-in-Aid for Early-Career Scientists
- Review Section
  
  Basic Section 50020:Tumor diagnostics and therapeutics-related
- Research Institution
  Kyoto University

All 2023 2022

All Journal Article Presentation

[Journal Article] Developing SHP2-based combination therapy for KRAS-amplified cancer2023
- Author(s)
  Tianxia Li, Osamu Kikuchi, Jin Zhou, Yichen Wang, Babita Pokharel, Klavdija Bastl, Prafulla Gokhale, Aine Knott, Yanxi Zhang, John G. Doench, Zandra V. Ho, Daniel V.T. Catenacci, and Adam J. Bass
- Journal Title
  
  JCI Insight
  
  Volume: - Issue: 3 Pages: 152714-152714
- DOI
  10.1172/jci.insight.152714
- Peer Reviewed / Open Access / Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16413
[Journal Article] Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study2022
- Author(s)
  Mori Yukiko、Kikuchi Osamu、Horimatsu Takahiro、Hara Hiroki、Hironaka Shuichi、Kojima Takashi、Kato Ken、Tsushima Takahiro、Ishihara Ryu、Mukai Kumi、Uozumi Ryuji、Tada Harue、Kasai Hiroi、Kawaguchi Atsushi、Muto Manabu
- Journal Title
  
  Esophagus
  
  Volume: Online Issue: 3 Pages: 444-451
- DOI
  10.1007/s10388-021-00905-2
- Peer Reviewed
- Data Source
  KAKENHI-PROJECT-20K16413
[Presentation] Developing combination therapy with SHP2 inhibition for CIN-type gastroesophageal adenocarcinoma with KRAS amplification2022
- Author(s)
  Osamu Kikuchi, Tianxia Li, and Adam Bass
- Organizer
  AACR Annual Meeting 2022
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16413
[Presentation] Developing combination therapy with SHP2 inhibition for CIN-type gastroesophageal adenocarcinoma with KRAS amplification2022
- Author(s)
  Osamu Kikuchi, Tianxia Li, Adam, Bass
- Organizer
  米国AACR Annual Meeting 2022 | April 8-13, 2022（発表確定） | New Orleans
- Int'l Joint Research
- Data Source
  KAKENHI-PROJECT-20K16413

1. 宮下美香 (60347424)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results
2. 木村貴子 (40990122)

# of Collaborated Projects: 1 results

# of Collaborated Products: 0 results

Kikuchi Osamu 菊池 理

Research Projects

Research Products

Co-Researchers

KRAS過剰活性化が誘導するがん細胞ストレス応答と脆弱性の解明Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Verifying the effectiveness and exploring the mechanism of cognitive training during chemotherapy for prevention of CRCI

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

KRAS増幅胃癌におけるSprouty経路の機序解明と分子標的療法の開発Principal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

Development of ferroptosis induction therapy against KRAS altered gastric cancerPrincipal Investigator

Principal Investigator

Project Period (FY)

Research Category

Review Section

Research Institution

[Journal Article] Developing SHP2-based combination therapy for KRAS-amplified cancer2023

Author(s)

Journal Title

DOI

Data Source

[Journal Article] Multicenter phase II study of trifluridine/tipiracil for esophageal squamous carcinoma refractory/intolerant to 5-fluorouracil, platinum compounds, and taxanes: the ECTAS study2022

Author(s)

Journal Title

DOI

Data Source

[Presentation] Developing combination therapy with SHP2 inhibition for CIN-type gastroesophageal adenocarcinoma with KRAS amplification2022

Author(s)

Organizer

Data Source

[Presentation] Developing combination therapy with SHP2 inhibition for CIN-type gastroesophageal adenocarcinoma with KRAS amplification2022

Author(s)

Organizer

Data Source

Kikuchi Osamu 菊池理